India is home to large number of under-five deaths and underweight children in the world which is mainly because of improper breastfeeding practices. Hence the study was conducted to assess the breastfeeding practices in tribal settings so that proper interventions can be planned by the health system staff to reduce infant morbidity and mortality. Cross-sectional study of three months duration from June 2011 to August 2011was conducted in tribal area of Khardi in Thane district amongst women who had delivered within one year of the study. This study was conducted in Khardi Primary Health Centre (PHC) which comprises of eight sub-centres. Five sub-centres among these eight sub-centres were selected randomly using lottery method. All tribal women, with infants between six months to twelve months of age, registered with these five sub-centres during their antenatal period were included as subjects. 153 such women were identified using universal sampling with the help of Auxillary Nurse Midwives (ANM) and Anganwadi Workers (AWW). 21 women were excluded due to non availability. House to house visits were paid to these subjects & they were then interviewed face to face using a questionnaire after taking their informed consent. Dependent variable was breastfeeding practices including exclusive breastfeeding and independent variables were all the socio-demographic factors influencing breastfeeding. Analysis was done with SPSS version 16. More than half (67.4%) infants were exclusively breast fed (EBF) up to six months of age. Pre-lacteal feeds were given to 23.5% infants while colostrum was not given to 15.2% infants. Practice of EBF was found to be significantly associated with advice regarding EBF during antenatal period, education status, parity of mother and sex of child. 67.4% of the infants were exclusively breastfed till six months of age. Religion, education of the mother, number of children of study subjects, sex of the baby and knowledge about EBF was found to be significantly associated with exclusive breastfeeding.
Breast Feeding ; Colostrum ; India

No abstract available.
Colostrum* ; Gastrins* ; Humans* ; Immunoglobulins* ; Milk*

No abstract available.
Colostrum* ; Humans ; Lymphocyte Subsets* ; Lymphocytes* ; Milk* ; Mothers*

No abstract available.
Colostrum* ; Humans ; Irritable Bowel Syndrome* ; Permeability*

Background: Early administration of colostrum is beneficial because of the number of its immunologic components. The problem with very low birthweight (VLBW) patients is the establishment of early, tolerated, and sustained feeding. The study aimed to determine if early initiation of colostrum through oropharyngeal administration within the first hour of life reduces the risk of late-onset sepsis (LOS) among VLBW newborns. Methods: In this single-blinded randomized control trial, 84 VLBW infants with pediatric aging equal to greater than 28 weeks requiring oxygen support were enrolled. They were allocated to receive either pasteurized colostrum via oropharyngeal administration (treatment group) or none (control group). The occurrence of LOS, duration of ventilator use and oxygen support, time to reach full feeds, length of NICU stay, the occurrence of NEC, and mortality were documented. Results: A significantly greater proportion of patients who developed LOS were noted in the control group (n=38 (90.4%)) than in the treatment group (n=30 (71.4%)) (p=0.013). The use of colostrum, had a protective effect for LOS (RR=0.77; 95% CI=0.63-0.94). There were no significant differences in the secondary outcomes. Still, there was a trend towards a lower proportion of mortality (p=0.08), shorter duration of ventilator use (p=0.24) and oxygen support (p=0.17), shorter time to reach full feeds (p=0.30), and shorter NICU stay (p=0.33) in the treatment group. Conclusion Patients given pasteurized colostrum had significantly less occurrence of LOS. The treatment group had a lower mortality rate, shorter ventilator use and oxygen support duration, faster time to reach full feeds, and shorter NICU stay, but the differences were not statistically significant. Oropharyngeal administration of pasteurized colostrum within the first hour of life reduces the risk of LOS among VLBW infants admitted to the NICU.
Neonatal Sepsis ; Colostrum ; Infant, Very Low Birth Weight

PURPOSE: We conducted this study to assess the effect of oral application of bovine colostrum on the plasma endotoxin and TNF-alpha following the abdominal surgery. METHODS: 46 patients who underwent the abdominal surgery were evenly enrolled in a prospective, randomized, double blind and placebo-controlled study. The patients were preoperatively managed by oral application of 20 g of a bovine colostrums or placebo (nonfat dried milk) per a day for 3 days. In both groups, endotoxin was sequentially determined pre-, intra- and postoperatively by a modified limulus amebocyte lysate test. TNF-alpha and CRP were also measured. The clinical course was followed and compared in both groups. RESULTS: The colostrum group showed significantly lower level of endotoxin and TNF-alpha compared to the placebo group. CRP did not differ in both groups. Clinical event did not occur in both group until the discharge. Colostrum group tends to have a lower incidence of fever and leukocytosis without statistic significance. CONCLUSION: Prophylactic preoperative oral application of bovine colostrum lower the plasma level of perioperative endotoxin and TNF-alpha. Further studies were needed for the relation of clinical effect and preoperative oral application of bovine colostrum.
Colostrum* ; Endotoxemia* ; Fever ; Horseshoe Crabs ; Humans ; Incidence ; Leukocytosis ; Plasma ; Prospective Studies ; Tumor Necrosis Factor-alpha*

The concentrations of Sodium and Potassium were measured by flame photometer in the human for milk obtained at clostral(1st 5days postpartum), early transitional (2nd 5days postpartum), late transitional (11th to 29th day postpartum) and mature milk period (1to 15 months postportum) from 92 healthy nursing mothers who delivered at term. The results were summerized as follows: 1) The concentrations of Na and K at different stages of lactation showed the highest value in colostrum, tended to decrease therafter and maintained the lowest and nearly constant value in mature milk(.01 2) Average Na and K concentrations(Mean+/-S.D., mEq/L) at different stages of lactation were colostrum : 20.8+/-4.47, 15.9+/-3.17, early transitional milk : 15.3+/-4.73, 14.2+/-3.03, late transitional milk : 11.7+/-4.28, 12.8+/-3.40, and mature milk : 8.1+/-3.59, 11.2+/-2.88 respectively. 3) The content of Na and K among primi-and multiparae showed the highest value in colostrum, also tended to decrease therafter, and maintained the lowest value in mature milk. No statistical significance was found between the concentrations of Na and K at different stages of lactation between primi-and multiparae(p>.05). 4) Definite inverse relationship could be established between Na and K concentrations and days of lactation(Na:r=-0.6, p<.001, K:r=0.4, p<.001). 5) The Mean Na and K concentration in late transitional milk showed the most consistent percentage decrease that in colostrum.
Colostrum ; Female ; Humans* ; Lactation* ; Milk ; Milk, Human* ; Mothers ; Nursing ; Potassium ; Sodium

This study was done to determine the trans fatty acid (tFA) composition of human milk from postpartum to sixth months after delivery, to investigate the tFA intake of lactating women, and to estimate the intakes of tFA by infants exclusively fed breast milk. A total of 27 lactating Korean women participated to this study voluntarily, gave their breast milk, and responded to an investigation of their diets. The lactating women consumed 2.3-2.8 g/d of tFAs over the period of the first, second, third, and sixth months postpartum, which was 3.4-4.9% of the total fat intake and 0.8%-1.2% of the total energy intake. The proportions of tFAs in the breast milk were 1.89% in colostrum, 1.78% in transitional milk, and 1.78-2.25 in mature milk of the first, second, third, and sixth months postpartum. The tFAs of the breast milk identified in this study were C16:1n9t, C18:1n9t, C18:2n6t12t, C18:2 n6t12c, C18:2n6c12t and C18:2n6t11t. Among them, C18:1n9t was predominant, which made up 59.26% of all tFAs in colostrum, 62.36% in transitional milk, and 64.42% in mature milk. The proportion of total tFA was unchanged with time, although some significant differences were noted for individual tFAs. The percentages of C18:2n6t12c and C18:2n6c12t decreased over the study period. Estimated tFA intake of the exclusively breast-fed infants was 0.18 g/d when fed colostrum, 0.29 g/d when fed transitional milk, and 0.53 g/d when fed mature milk until the sixth month of postpartum. Those were 0.5%, 0.8%, and 1.1% of the total energy intake. The results in this study indicate that lactating Korean women consume not a large quantity of tFAs, secrete breast milk not containing much tFA, and the estimated intake of tFAs by infants fed exclusively breast milk is not great.
Breast* ; Colostrum ; Diet ; Energy Intake ; Female ; Humans ; Infant ; Milk ; Milk, Human* ; Postpartum Period* ; Trans Fatty Acids*

Two 4-day-old Thoroughbred foals with acute clinical signs of depression, elevated pulse and respiratory rates, anemia, and jaundice were referred to the equine hospital of Korea Racing Authority. The foals were seemingly normal at birth, but showed clinical signs such as abnormal behavior, jaundice and anemia suddenly after ingestion of the mare's colostrum, followed by death at 4 days after birth. According to the results of the hematology, serum chemistry analysis, jaundice foal agglutination test, and blood groups test, the foals were diagnosed as neonatal isoerythrolysis (NI) caused by the mare's antibodies. These results suggested that the pregnant mares have a potential for NI.
Agglutination Tests ; Anemia ; Antibodies ; Blood Group Antigens ; Colostrum ; Continental Population Groups ; Depression ; Eating ; Hematology ; Humans ; Jaundice ; Korea ; Parturition ; Respiratory Rate

The study evaluated whether a transgenic carrot vaccine could induce a K88-specific immune response in sows and whether the resultant maternal antibody could protect piglets against enterotoxigenic Escherichia coli (ETEC) K88ac infection. Sows (n = 15) selected randomly from a farm in Korea were assigned to three groups (n = 5 per group: control [untreated]), group A (orally inoculated with a non-transgenic and transgenic carrot vaccines at 2 and 4 weeks ante partum, respectively), and group B (conventionally vaccinated according to the manufacturer's instructions). After 7 days of lactation, 5 piglets selected randomly from each group were challenged with 1 x 1010 colony forming units/mL ETEC K88ac. Group C had the lowest mean fecal consistency score on post-challenge days 1 and 7. Histiologically, On post-challenge day 7, group C showed an increased duodenum and ileum villus:crypt ratio, compared to group A in the duodenum, with group B displaying the highest ratio. Groups B and C had more increased villus width than group A in the jejunum. Group C displayed the greatest increase in villus width in the ileum. The colostrums and serum from groups B and C displayed higher concentrations of IgA and IgG against ETEC K88, compared to group A. Based on the results, it was concluded that the transgenic carrot vaccine in sow per oral may have an effect on preventing piglet diarrhea as good as commercial recombinant vaccine.
Ants ; Colostrum ; Daucus carota ; Diarrhea ; Duodenum ; Enterotoxigenic Escherichia coli ; Female ; Ileum ; Immunoglobulin A ; Immunoglobulin G ; Jejunum ; Korea ; Lactation ; Vaccines