1.Treatment of Steroid Refractory Ulcerative Colitis.
The Korean Journal of Gastroenterology 2006;48(4):290-291
No abstract availble.
Colitis, Ulcerative/complications/*diagnosis/pathology
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Colonoscopy
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Female
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Humans
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Intestinal Obstruction/*diagnosis/etiology/pathology
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Middle Aged
2.A Case of Pulmonary Thromboembolism in Active Ulcerative Colitis.
Byoung Do PARK ; Hyung Gil KIM ; Hyun Jung JUNG ; Yong Jun CHOI ; Sang Gu KIM ; Soo Han KIM ; Gye Sug KWON ; Yong Woon SHIN
The Korean Journal of Gastroenterology 2009;53(1):48-52
Inflammatory bowel disease often involves extra-intestinal organs. Cerebral thrombosis, portal vein thrombosis and pulmonary thrombosis have been reported. Deep vein thrombosis and pulmonary thromboembolism are significant causes of mortality in patients with inflammatory bowel disease. A 48-year-old woman was diagnosed as inflammatory bowel disease on colonoscopy and histology. We used hydrocortisone and mesalazine for the treatment of disease. Nineteen days later, she complained of abrupt dyspnea. Pulmonary CT angiography revealed a thromboembolism in right pulmonary arteries. After the treatment of heparin therapy, follow-up pulmonary CT angiography showed significant improvement of previously thrombosed pulmonary arteries.
Acute Disease
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Colitis, Ulcerative/complications/*diagnosis
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Colonoscopy
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Female
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Humans
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Middle Aged
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Pulmonary Embolism/*diagnosis/etiology/pathology
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Tomography, X-Ray Computed
3.Atypical clinical manifestations of amebic colitis.
Jung Hwan YOON ; Ji Gon RYU ; Jong Kyun LEE ; Sae Jin YOON ; Hyun Chae JUNG ; In Sung SONG ; Kyoo Wan CHOI ; Chung Yong KIM
Journal of Korean Medical Science 1991;6(3):260-266
Amebic colitis is a disease revealing diverse clinical manifestations and endoscopic gross features and often confused with other types of colitis. In case of misdiagnosis as an idiopathic inflammatory bowel disease or delayed recognition of intestinal amebiasis, an undesirable outcome may occur resulting from erroneous administration of steroids or delayed antiamebic treatment. To demonstrate the pitfalls in the diagnosis and treatment of intestinal amebiasis, 3 cases of amebic colitis with atypical clinical manifestations are presented in this paper. In conclusion, despite the low sensitivities of routine stool examination for parasite and histopathologic confirmation in biopsy specimen, every effort must be made to find amebic trophozoites either in fresh stool or biopsy specimens for prompt and correct diagnosis of amebic colitis when we manage patients with chronic intestinal ulcerations, even though their clinical course and endoscopic findings are not typical of amebiasis. Moreover, following initial successful anti-amebic therapy, more careful clinical, endoscopical, and parasitological follow-up should be done for the early detection of recurrence.
Adult
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Aged
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Aged, 80 and over
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Colitis, Ulcerative/diagnosis
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Diagnosis, Differential
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Diarrhea/etiology
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Dysentery, Amebic/complications/drug therapy/*pathology
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Female
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Humans
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Inflammatory Bowel Diseases/diagnosis
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Male
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Middle Aged
5.A Case of Steroid Resistant Autoimmune Hemolytic Anemia in Ulcerative Colitis.
Hyun Jong CHOI ; Su Jin HONG ; Young Jee KIM ; Bong Min KO ; Moon Sung LEE ; Chan Sup SHIM ; Hyun Jung KIM ; Dae Sik HONG
The Korean Journal of Gastroenterology 2008;51(2):137-141
Autoimmunity is thought to play a central role in the pathogenesis of inflammatory bowel disease and associated extraintestinal manifestations. Autoimmune hemolytic anemia associated with ulcerative colitis is a rare occurrence. No more than 50 cases have been described in the international literatures, and only 2 cases reported in Korea. A 29-year-old woman who was diagnosed as ulcerative colitis two years ago was complicated with autoimmune hemolytic anemia, and did not respond to steroid therapy. Ultimately, total colectomy and splenectomy were carried out for the treatment of ulcerative colitis and hemolytic anemia. After the operation, anemia was resolved. We present the case with a review of literature.
Adult
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Anemia, Hemolytic, Autoimmune/*diagnosis/drug therapy/etiology
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Colectomy
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Colitis, Ulcerative/complications/*diagnosis/pathology
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Drug Resistance
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Female
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Humans
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Splenectomy
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Steroids/therapeutic use
6.A Case of Renal Vein Thrombosis in a Patient with Ulcerative Colitis.
Dong Jin YANG ; Young Sook PARK ; Yeon Hwa YU ; Yun Ju JO ; Seong Hwan KIM ; Yoon Young JUNG ; Young Hwan HWANG ; Dae Won JUN
The Korean Journal of Gastroenterology 2009;54(4):248-251
Venous thrombosis and thromboembolism appear to occur more often in patient with inflammatory bowel disease (IBD). The cause of thrombotic complications in IBD is generally considered to be associated with hypercoagulable conditions. Its prevalence rate ranges from 1% to 8% in clinical studies and rises to 39% in autopsy, but the renal vein thrombosis is very rare complication in ulcerative colitis patient. A 24-year-old man presented with intermittent abdominal pain and hematochezia for 6 months and recently developed pitting edema for few weeks. He was diagnosed as severe ulcerative colitis involving whole colon combined with thrombosis in both renal veins by colonoscopy and computed tomography scan of abdomen. We used steroid for the treatment of ulcerative colitis and both intravenous lower molecular weight heparin and warfarin for renal vein thrombosis. His symptoms were improved after treatment and maintained with mesalazine and warfarin. Follow-up abdominal CT scan showed complete resolution of both renal vein thrombosis. Currently he has been followed up for 2 years with oral mesalazine.
Anticoagulants/therapeutic use
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Colitis, Ulcerative/complications/*diagnosis/pathology
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Colonoscopy
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Heparin/therapeutic use
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Humans
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Male
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Protein S/metabolism
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*Renal Veins
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Tomography, X-Ray Computed
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Venous Thrombosis/complications/*diagnosis/radiography
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Warfarin/therapeutic use
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Young Adult
7.Pulmonary Toxocariasis Mimicking Invasive Aspergillosis in a Patient with Ulcerative Colitis.
Eun Jin PARK ; Joon Young SONG ; Min Ju CHOI ; Ji Ho JEON ; Jah yeon CHOI ; Tae Un YANG ; Kyung Wook HONG ; Ji Yun NOH ; Hee Jin CHEONG ; Woo Joo KIM
The Korean Journal of Parasitology 2014;52(4):425-428
A 45-year-old-male who had underlying ulcerative colitis and presented with fever and dry cough. Initially, the patient was considered to have invasive aspergillosis due to a positive galactomannan assay. He was treated with amphotericin B followed by voriconazole. Nevertheless, the patient deteriorated clinically and radiographically. The lung biopsy revealed eosinophilic pneumonia, and ELISA for Toxocara antigen was positive, leading to a diagnosis of pulmonary toxocariasis. After a 10-day treatment course with albendazole and adjunctive steroids, the patient recovered completely without any sequelae. Pulmonary toxocariasis may be considered in patients with subacute or chronic pneumonia unresponsive to antibiotic agents, particularly in cases with eosinophilia.
Albendazole/therapeutic use
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Animals
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Anthelmintics/therapeutic use
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Anti-Inflammatory Agents/therapeutic use
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Antigens, Helminth/analysis
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Colitis, Ulcerative/*complications
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Diagnosis, Differential
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Enzyme-Linked Immunosorbent Assay
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Humans
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Lung/pathology
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Lung Diseases, Parasitic/*diagnosis/*pathology
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Male
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Middle Aged
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Pulmonary Aspergillosis/diagnosis/pathology
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Steroids/therapeutic use
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Toxocara/*isolation & purification
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Toxocariasis/*diagnosis/*pathology
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Treatment Outcome
8.A Case of Hemophagocytic Syndrome in an Ulcerative Colitis Patient.
Yong Cheol KIM ; Gun Min KIM ; Ho Sang LEE ; Seok In HONG ; Dae Young CHEUNG ; Jin Il KIM ; Soo Heon PARK ; Jae Kwang KIM
The Korean Journal of Gastroenterology 2010;56(1):45-48
A case of hemophagocytic syndrome associated with ulcerative colitis is very rare. A 32-year-old man visited the hospital complaining of fever and severe abdominal pain for 7 days. He was diagnosed to have ulcerative colitis 2 years ago and had been treated with sulfasalazine. Three months ago, he had abdominal pain, weight loss, and hematochezia, so prednisolone and mercaptopurine were added to the treatment. On admission, the physical examination showed splenomegaly. Peripheral blood counts revealed pancytopenia, and bone marrow aspirate smears showed many histiocytes with active hemophagocytosis. There was no evidence of viral and bacterial infections and other neoplasms, which were commonly associated with hemophagocytic syndrome. He was successfully treated with high dose steroid. We report this case along with a review of the related literatures.
6-Mercaptopurine/therapeutic use
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Adult
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Anti-Inflammatory Agents/therapeutic use
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Anti-Inflammatory Agents, Non-Steroidal/therapeutic use
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Bone Marrow Cells/pathology
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Colitis, Ulcerative/complications/*diagnosis/drug therapy
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Colonoscopy
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Dexamethasone/therapeutic use
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Humans
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Immunosuppressive Agents/therapeutic use
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Lymphohistiocytosis, Hemophagocytic/complications/*diagnosis/drug therapy
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Male
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Prednisolone/therapeutic use
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Sulfasalazine/therapeutic use
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Syndrome
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Tomography, X-Ray Computed