OBJECTIVES: Intra-individual variability of cognitive performance across different tests or domains has been reported as an important index of cognitive function. The aim of the current study is to examine the intra-individual variability across different cognitive domains and tests in patients with schizophrenia, their unaffected siblings, and normal controls. We also compared the variability among three patient sub-groups divided according to the duration of illness. METHODS: Comprehensive neurocognitive tests were administered in order to stabilize patients with schizophrenia (n=129), healthy siblings (n=38) of the patients, and normal controls (n=110). Intra-individual variability was computed from the variance of the scores of six cognitive domains of the Measurement and Treatment Research to Improve Cognition in Schizophrenia consensus battery. We examined intra-individual variability across six factor-based cognitive scores and individual test scores of each cognitive domain. RESULTS: Compared to the normal control and sibling groups, patients showed significantly increased intra-individual variability across six cognitive domains and individual cognitive tests of each domain. Compared to the normal control, siblings showed significantly increased intra-individual variability only across individual tests of the processing of speed domain. Among patient sub-groups, those with the longest duration of illness (> or =11 years) showed significantly higher intra- individual variability across six cognitive domains and across individual tests of the processing of speed domain compared to the other two groups. CONCLUSION: This study identified cognitive dissonances across six cognitive domain schizophrenia patients. These cognitive characteristics were not observed in the sibling groups and seemed to progress during the course of illness.
Cognition ; Cognitive Dissonance ; Consensus ; Humans ; Neuropsychological Tests* ; Schizophrenia* ; Siblings*

PURPOSE: The purpose of this study was to investigate cognitive function, leisure activities and depression in female elderly, to examine the relationships among those variables and to investigate leisure activities and depression according to cognitive function. METHODS: The subjects were 105 female elderly visiting two senior citizen centers in Seoul, Korea. Data were collected from November to December 2006. The participants were assured of anonymity and confidentiality. All information was collected through face-to-face interviews using questionnaires. RESULTS: 26.0% of the participants were cognitive impaired but not demented and 17.3% were demented. The level of depression was severe and 77.9% of the subjects were depressed. The subjects were not actively engaging in leisure activities. There were significant correlations between cognitive function, leisure activities and depression in female elderly. Demented or CIND subjects were more actively engaging in extra family fulfillment type leisure activities than normal subjects, CONCLUSION: These findings showed the need for a program for female elderly regarding leisure activities. When counseling the elderly, nurses must consider their cognitive function, leisure activities and depression.
Aged* ; Anonyms and Pseudonyms ; Cognitive Dissonance ; Confidentiality ; Counseling ; Depression* ; Female* ; Humans ; Korea ; Leisure Activities* ; Seoul ; Surveys and Questionnaires