Cleft Lip ; surgery ; Cleft Palate ; surgery ; Humans ; Maxillofacial Development ; physiology

The Department of Plastic Surgery of the Yonsei University College of Medicine in Korea studied 2422 cases of cleft lip and cleft palate patients for 20 years An analysis of the date resulted in the following: 1) of the 33,130 live births in our hospital in 20 years (Jan. 1962-Dec. 1981), 44 of the birth certificates specified cleft lip or palate. This is a ratio of 1.33 cases per 1000 live births. 2) The ratios for left to right to bilateral cleft was 3.4:1.9:1.0. Higher percentage of males than females had cleft lip-palate combined, than cleft lip only. A higher percentage of females had cleft palate only. 3) A positive family history was noted in 151 out of 2422 cases; (6.3%). 4) 45% of the patients had an associated congenital malforation of which heart anomaly was the most common. 5) Lip closure was scheduled to be done within 3 months of age; palate closure was scheduled between 12 to 18 months. 6) The triangular flap method was used for the lip repair. The palate was repaired by the KilnerWardill method in all cases. The operative results were satisfactory m both lip controur and speech. Noting the lack of published reports about this topic, especially among the oricental population, we believe this paper will serve to enhance the knowledge of the field of cleft lip and cleft palate patients in Asia.
Cleft Lip/epidemiology* ; Cleft Lip/genetics ; Cleft Lip/surgery ; Cleft Palate/epidemiology* ; Cleft Palate/genetics ; Cleft Palate/surgery ; Female ; Human ; Infant ; Infant, Newborn ; Korea ; Male

Cleft Palate ; surgery ; Humans ; Models, Theoretical

No abstract available.
Cleft Lip ; Humans ; Orthognathic Surgery ; Palate

OBJECTIVETo investigate the mechanism of new bone formation in the distraction osteogenesis (DO) for correction of cleft palate (CP) in rhesus.

METHODSCP was created by operation in 23 rhesus. The CP was corrected with DO in 21 animals as experimental group. The distraction rate was 0.8 mm per day, two times a day. The bone fragments were fixed after cleft closure, every 3 animals were sacrificed to get specimen after 1, 2, 4, 6, 8, 12, 24 weeks of fixation. 6 days before sacrifice, tetracycline was administrated for labeling (30 mg/kg).

RESULTSThe hard and soft tissue def of fixation. At the same time, the bone volume and calcification between the distraction gap increased. The cleft in the control group could not b ect was successfully closed with DO by intramembrane osteogenesis. The new formed bone was remodeling and became maturation during the period e corrected spontaneously.

CONCLUSIONSThe DO can successfully correct both the soft and hard tissue defect in CP by intramembrane osteogenesis. The fixation is important for remodeling and maturation of the new formed bone.

Animals ; Biomarkers ; Cleft Palate ; pathology ; surgery ; Macaca ; Osteogenesis, Distraction ; Palate, Hard ; pathology ; Palate, Soft ; pathology

OBJECTIVETo compare results of the growth and development of the upper dental arch and the velopharyngeal closure of the cleft patients treated by two methods.

METHODSThe dental cast of patient and X-ray films were measured and the statistical medical records were analyzed.

RESULTSThe transverse distance of upper dental arch was found to be wider in group A than in group B. The anterior-posterior distance of the dental arch in bilateral cleft group was shorter in group A than in group B. The difference of the two groups were gradually lessened as age increases. Bony bridge in alveolar gap was 63% and 83.3% in unilateral and bilateral cleft group respectively. 15% of cases in group A and 35.2% in group B needed pharyngeal flap.

CONCLUSIONSThe stable upper dental arch in group A can opposes the pressure from the lip muscles, this maintains the width of the arch. But A-P distance of upper dental arch in BCLP in group A should be followed up after the age of 9 years. Pharyngeal flap is needed less in group A than in group B.

Alveolar Process ; growth & development ; Child ; Child, Preschool ; Cleft Lip ; surgery ; Cleft Palate ; surgery ; Humans ; Infant ; Orthodontics, Corrective ; Palate, Soft ; surgery

OBJECTIVEThe purpose of this study was to retrospect the prognosis of simultaneous repair of cleft lip and closure of cleft hard palate with vomer flaps in patients with unilateral complete cleft lip and palate.

METHODSA retrospective study was carried out in 47 patients with unilateral complete cleft lip and palate and, simultaneously received repair of cleft lip and closure of cleft hard palate with vomer flaps. The duration of operation, as well as the blood loss during the operation was recorded, and compared with those patients who only received cleft lip repair.

RESULTSAll the operations were successful, and the wound healed well. The procedure of simultaneous repair of cleft lip and closure of cleft hard palate with vomer flaps did not prolong the operating time, compared with simple cleft lip repair. No blood transfusion was needed due to closure of cleft hard palates with vomer flaps.

CONCLUSIONSimultaneous repairs of cleft lip and closure of cleft hard palate with vomer flaps are safe for patients with unilateral complete cleft lip and palate.

Abnormalities, Multiple ; surgery ; Cleft Lip ; surgery ; Cleft Palate ; surgery ; Female ; Humans ; Infant ; Male ; Maxillofacial Development ; Palate, Hard ; surgery ; Palate, Soft ; surgery ; Reconstructive Surgical Procedures ; methods ; Surgical Flaps

Animals ; Cleft Palate ; surgery ; Humans ; Reconstructive Surgical Procedures ; methods

Patients with complete unilateral cleft lip and palate present difficulty in maxillary growth problems, necessitating orthognathic surgery in 25%. The aims of this study were; (1) to delineate diagnostic measures in borderline surgical cases of unilateral cleft lip and palate, (2) to verify the significance of negative overjet as a measure of anteroposterior discrepancy, and (3) to compare these diagnostic measures with those of borderline surgical cases of noncleft Class III malocclusion. The sample consisted of 29 patients with unilateral cleft lip and palate and 25 noncleft Class III patients; all had crossbites of all four incisors. Each of pretreatment study casts and cephalograms were analyzed. The Cleft group showed smaller SNA and SNB angles than the noncleft Class III group, but the ANB angles and the amount of anterior crossbites showed no statistical difference. For borderline surgical Class III unilateral cleft lip and palate cases, ANB angles, Wits appraisal, and ABGoGn angle were critical diagnostic parameters. On the other hand, the magnitude of anterior crossbite, the negative overjet, was shown not to be a significant measure of anteroposterior discrepancy.
Cleft Lip* ; Hand ; Humans ; Incisor ; Malocclusion* ; Orthognathic Surgery ; Palate*

OBJECTIVETo explore an effective method to diagnose and treat the congenital recessive cleft palate.

METHODSFor the treatment of congenital recessive cleft palate, an operation was designed to recover the anatomic length and function mobility of the soft palate. The operation procedure includes incising vertically the midline mucous membrane of the soft palate, creating and pushing back the mucosal flap of the hard palate, making Z-plasty on the nasal mucosa, reconstructing the sling of the levator veli palatini muscle and repairing the palatal defects with the buccinator muscularis mucosae flap. 12 cases of congenital recessive cleft palate have treated with this method.

RESULTSAll of the 12 cases obtained good results. Their pronunciation improved obviously.

CONCLUSIONThe method is effective for diagnosis and treatment of congenital recessive palate, which is worthy of further application.

Adolescent ; Child ; Cleft Palate ; diagnosis ; surgery ; Female ; Humans ; Male