1.Antimicrobial and barrier repair properties of virgin coconut oil and mineral oil in pediatric atopic dermatitis patients, a randomized, double-blind, control trial.
Journal of the Philippine Medical Association 2020;99(1):1-9
BACKGROUND:
Atopic dermatitis (AD) is a chronic
relapsing skin disease in childhood, managed by
topical therapies. In the Philippines, use of
affordable, widely available and effective
alternative therapies such as mineral oil (MO) and
virgin coconut oil (VCO), are practical especially in
the far-flung areas.
OBJECTIVES:
This study compares the antimicrobial
and barrier repair properties of MO and VCO in mild
to moderate atopic dermatitis, using SCORAD
(SCORing for Atopic Dermatitis), bacterial culture,
tewameter, mexameter and corneometer.
METHODS:
This is a randomized controlled doubleblind
trial conducted in two tertiary hospitals.
Bacterial colonies, transepidermal water loss
(TEWL), level of hydration and erythema were
determined at baseline and after 4 weeks using
bacterial culture, tewameter, corneometer and
mexameter, respectively. SCORAD and adverse
effects were also determined at baseline, 2nd and
4th week of treatment.
RESULTS:
Baseline patient demographics were
similar for both treatment groups. The SCORAD,
TEWL and level of erythema were significantly
decreased throughout the 4-week duration for both
treatment groups, but much lower in the VCO group.
The hydration level was significantly increased
throughout the 4-week duration but much higher for
the VCO group. Lastly, there is more proportion of
cultures with "no growth" after the 4-week
treatment duration in VCO group.
CONCLUSION
The antimicrobial and barrier repair
properties of VCO are very important alternative
which is affordable, readily available, safe and
effective for children with mild to moderate AD.
Dermatitis, Atopic
;
Philippines
2.Disseminated zoster in an immunocompromised.
Journal of the Philippine Medical Association 2020;99(1):57-62
In an immunocompromised patient such as
HIV infection, disseminated herpes zoster is a
common cutaneous manifestation. It is very
important to have clinical suspicion of HIV,
whenever a patient presents with cutaneous
manifestation of HIV. This is a case of a 32 year old
male who came in at for consult at our institution
with a chief complaint of fluid filled bumps which
started on the left abdominal area progressing to
the trunk, upper and lower extremities with
associated pricking pain. Patient was diagnosed
with disseminated zoster and was given acyclovir
with noted complete resolution of lesions.
Laboratory tests were requested which revealed
that the patient also had concomitant HIV and
Hepatitis B. Patient was referred to the Center for
Tropical and Travel Medicine for proper
management.
HIV
;
Hepatitis B
;
Acyclovir