OBJECTIVETo investigate the chemical constituents in Cicuta virosa var. latisecta.
METHODMany kinds of column chromatography were used to isolate the compounds from the EtOH ext. of C. virosa var. latisecta. The chemical constituents of the plant were identified by means of IR, MS, 1H-NMR, 13C-NMR, respectively, in some case by direct comparison with authentic samples.
RESULTNine compounds were isolated from the aerial part and were identified as: 3beta-acetyloxy-16-hydroxy-olean-12-en-28-oic acid (1), 9 (11), 12-dieneoleana-3beta-ol (2), 9, 19-cyclolanaost-24-en-3-one (3), 9, 19-cycloergost-23-en-3, 25-diol (4), stigmasterol (5), falcarindiol (6), 1, 2-benzenedicarboxylic acid, his (2-ethylhexyl) ester (7), stigmast-5-en-3beta-ol (8), beta-daucosterol (9).
CONCLUSIONCompound 1 is a new natural product, and compounds 2 to 9 were firstly isolated from this plant.
Cicuta
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chemistry
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Organic Chemicals
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analysis
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isolation & purification
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Plant Components, Aerial
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chemistry