Objective:To analyze the influence of cardiac rhythm on image quality in coronary angiography with 64-slice spiral CT and to investigate the value of ECG editing in improving the image quality of arrhythmias.Methods:A retrospective study was undertaken in 112 cases which had 64-spiral CT scan in coronary angiography.The 112 cases were divided into 4 groups according to the heart rate fluctuation.Group A 0～4 bpm,Group B 5～9 bpm,Group C 10～14 bpm,and Group D≥15 bpm.The image qualities of brands or segments of coronary arteries(total 1 118)were compared between different groups;26 patients with previously known arrhythmia or arrhythmia merely occurring during the examination,their coronary angiographies were obtained respectively using original synchronously record ECG or using the ECG after being edited with the ECG editing software.The image quality was compared before and after the editing.Results:There was no significant difference between group A、B and C except RCA2,but the difference between group D and A、B、C was obvious(P

Objective To investigate the role of losartan in AT2-R mediated renal protective effects in renovascular hypertension rat. Methods Male SD rats were divided into sham group and renovascular hypertension group in which Goldblatt methods were performed. The two groups were intragastically administered with losartan (respectively 0, 10, 20, 30 mg?kg-1?d-1) for 6 weeks. Then renal function was measured, the AT2-R expression in the non-ischemic kidney and the AngⅡ contents in non-ischemic kidney and plasma were determined. Results In renovascular hypertension rats, especially in the contralateral, non-ischemic kidney, the expression of AT2-R protein were up-regulated. Losartan increased the AngⅡ contents in non-ischemic kidney and plasma, mediated the natriuretic/diuretic effect and renal protective effect in renovascular hypertension rat and increased the expression of renal AT2-R. Conclusion In renovascular hypertension rat, losartan mediates renal natriuretic/diuretic effect and protects renal function through up-regulating AT2-R in kidney.

Objective To investigate the effect of simulated 400 m He-O2 saturation diving on the pulmonary oxidative-antioxidative system in rats.Methods SD rats were exposed to 4.1 MPa He-O2 mixture for 24 h in an animal chamber. Normal air pressure was used in the control group .The histopathology , contents of malondialdehyde ( MDA) , 8-hydroxy-2′-deoxyguanosine(8-OHdG),and glutathione(GSH) and activities of superoxide dismutase (SOD) and glutathione peroxi-dase( GSH-Px) in pulmonary tissues were determined .Results No difference was found during pathological examination or in MDA, 8-OHdG and SOD activity.GSH and GSH-Px activity were decreased significantly (P<0.05) after hyperbaric exposure.Conclusion Exposure to 4.1 MPa He-O2 for 24 h may promote oxidative stress and reduce antioxidative capacity rather than cause obvious oxidative damage in rat lungs .

Objective To investigate the preoperative evaluating accuracy of liver cancer using one-stop imaging quantification technique of 320 row CT and its clinical application value.Methods 42 patients with primary mass-forming liver cancers underwent one-stop imaging by 320 row CT,including enhancement imaging,perfusion quantification,liver volume quantification and angiogra-phy.After surgery,the volume of excised livers were measured.Liver function was also evaluated.Results After liver perfusion quantification,significant differences in hepatic artery flow,portal venous flow and hepatic artery perfusion index were found be-tween the 42 cases of mass-forming liver cancers and normal liver tissues (P <0.05).No significant difference was found between preoperative quantified liver volume and postoperative measured liver volume (P >0.05).The diagnostic accuracy by CT angiogra-phy was up to 40/42 cases (95.2%)through surgical verification.The diagnostic accuracy of large blood vessels and the first or sec-ond level branches were 100%.Conclusion The quantitative analysis of one-stop imaging technique by 320 rows CT can accurately evaluate the liver perfusion,angio-architecture and liver volume before surgery.

Objective To investigate the predisposing factors and clinical features of disseminated herpes zoster, and to explore factors influencing postherpetic neuralgia. Methods Clinical data were collected from 53 patients with disseminated herpes zoster and 809 patients with common herpes zoster between 2012 and 2015, and analyzed retrospectively. Logistic regression analysis was used to assess factors influencing the occurrence of and pain intensity in disseminated herpes zoster, as well as the occurrence of postherpetic neuralgia. Results No significant difference in patients′age was observed between the disseminated and common herpes zoster groups(56.66 ± 17.24 vs. 56.50 ± 15.51 years, t=0.071, P>0.05), but there was a significant difference in the gender ratio between the two groups(χ2 = 8.16, P = 0.004). The incidence rates of bullae, pustules and fever were all significantly higher in the disseminated herpes zoster group than in the common herpes zoster group(15.09%vs. 3.58%,χ2=16.04, P<0.01;47.17%vs. 26.82%,χ2=10.20, P<0.01;30.19%vs. 8.03%,χ2=28.68, P<0.01). The disseminated herpes zoster group also showed significantly higher pain scores at admission compared with the common herpes zoster group (Median[P25- P75]: 6[4- 7.5] vs. 5[3- 7], Z =-3.460, P = 0.001). Logistic regression analysis revealed that gender, age, fatigue and HIV infection were significantly associated with the occurrence of disseminated herpes zoster (all P<0.05). Additionally, HIV infection(OR=5.570, 95%CI:1.196-25.939, P=0.029), gender(OR=0.166, 95%CI:0.029-0.945, P=0.043), age(OR=1.064, 95%CI:1.010-1.119, P=0.019)and the number of days that antiviral therapy lasted(OR=0.669, 95%CI:0.505-0.885, P=0.005)were all factors influencing the occurrence of postherpetic neuralgia. Conclusion Male, old age, fatigue and especially HIV infection are risk factors for the occurrence of disseminated herpes zoster, and male, old age and antiviral therapy duration may be associated with the occurrence of postherpetic neuralgia.

Objective To analyze the district differences of height among Chinese Han population aged 7 to 18 years,and to divide the levels of heights into several regions accordingly,to provide basis for evaluation the development of height in the above said population.Methods Standard Deviation was used to compare the relative lavels of height in different provinces and to divide them into several regions.The results were then showed in map through the Geographic Information System (GIS).Results All the 30 provinces in China were divided into three regions:high,medium and short regions according to the stature.Region with high stature was mainly located in northern,while medium stature was in central and northwest parts and short stature was in southwest parts of China.The differences of height appeared to be significant among regions in every age group.The differences of height were 1-3 cm between adjacent regions,and were even lager between the regions with high or short stature which appeared to be 4-5 cm.Conclusion Overall,heights among the Chinese Han children and adolescents were taller in the northern and shorter in the southern areas.The highest and lowest levels of heights were in the Northern and the Southwest areas respectively.It was observed that the levels of height in the coastal areas were higher than that of the inland.There were no absolute boundaries between different regions because of the gradual transition in the levels of heights in various districts.

Objective To develop the reference on height among children and adolescents aged 7 to 18 years of Chinese Han ethnicity in different administrative districts of China and to use this height reference for screening stunting.Results from the national screening program were compared with the WHO references.Methods Data from the Chinese National Survey on Students Constitution and Health in 2005 was used to develop the height references through LMS method.Results Differences among the references on height for children and adolescents in different districts ( Ⅰ - Ⅳ ) were remarkable.The highest was seen in the Second Districts while the lowest was seen in the First Districts among those at the age of 18,with differences as 3.18 cm for boys and 2.92 cm for girls.The heights from the inland were shorter than that of the WHO references,with the differences ranging from 0.31 cm to 5.07 cm for boys,and from 0.98 cm to 4.22 cm for girls.The prevalence rates of stunting were 2.22％,2.29％,5.25％,respectively according to local references,national references and the WHO references.Conclusion Universal height references from the whole nation could not discriminate the variations caused by geographic conditions and hereditory factors related to socio-economie situations.Height references should be developed locally,to evaluate height levels of the areas.

0.05).Compared with the CSS,GMFM and WV before treatment,there were statistically difference after 6 and 12 weeks treatment in two groups(Pa

Arthropods of medical importance such as mosquitoes, ticks and sandflies are one of the key drivers of arthropod-borne diseases outbreak, posing a great threat to global public health security. For further understanding the transmission mechanisms of arthropod-borne diseases and establishing the prevention and control measures, a series of experiments of arthropods infection need to be carried out under laboratory conditions. Besides the regular biosafety requirements, some specific considerations need to be taken into account when performing arthropod infection and the infected arthropod rearing. Except for the physical containment composed of biosafety facilities, a comprehensive assessment of the biosafety risks during operations and corresponding preventive measures are also critical to eliminate or mitigate the biosafety risks. In this paper, we introduce our practice in handling mosquito infection with Risk Group 2 pathogens in Arthropod Containment Level-2 (ACL-2) laboratory, with an aim to provide a reference for researchers in related fields.

Objective: To examine the association of long working hours and shift work with occupational stress among medical staff in level A tertiary hospitals, so as to provide insights into promotion of physical and mental health among medical personnel. Methods: One level A tertiary hospital was sampled using a stratified cluster sampling method from southern and northern Xinjiang Uygur Autonomous Region, and all medical personnel were recruited from these two hospitals. Participants' demographics, working duration, and working in shifts were collected using questionnaires, and occupational stress was measured using the Core Scale for Measurement of Occupational Stress proposed by National Institute for Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention. The associations of long working hours (weekly working duration of >40 hours) and shift work with occupational stress were examined using a multiple linear regression model. Results: A total of 2 529 questionnaires were allocated, and 2 262 were valid, with an effective rate of 89.44%. The respondents had a mean age of (35.12±8.71) years, and included 1 696 women (74.98%). Of all respondents, there were 722 doctors (31.92%), 1 033 nurses (45.67%), 361 medical or pharmaceutical technicians (15.96%), 1 808 with long working hours (79.93%) and 1 264 with shift work (55.88%). The score of occupational stress was (44.79±8.49) points, and the prevalence of occupational stress was 28.69% among respondents. Multiple linear regression analysis showed that after adjustment for age, marital status, length of service, position, smoking and physical exercise, long working hours (>40 h, β'=0.124; >48 h, β'=0.175; ≥55 h, β'=0.323) and shift work (β'=0.203) were influencing factors for occupational stress among medical personnel（P<0.05）; however, there was no interaction between long working hours and shift work (P>0.05). Conclusion Long working hours and shift work may increase the risk of occupational stress among medical personnel in level A tertiary hospitals.