1.Etiology of 96 syncope patients
Chinese Journal of Geriatric Heart Brain and Vessel Diseases 2017;19(9):971-973
Objective To study the diagnosis and treatment of syncope by analyzing its etiology.Methods Ninety-six syncope patients admitted to our hospital from 2014-01-01 to 2016-12-21were included in this study.The etiology of syncope was analyzed.Results Of the 96 syncope patients included in this study,50 (52.1 %) were diagnosed with nerve-mediated reflex syncope,31(32.3%) with orthostatic hypotensive syncope,10 (10.4%) with cardiogenic syncope due to arrhythmia,coronary atherosclerotic cardiopathy or pulmonary embolism,5 (5.2%) with other diseases.Conclusion Nerve-mediated reflex,orthostatic hypotension and cardiogenic factors are the causes of syncope.Attention should thus be paid to syncope caused by nervous system diseases.Clarification of the risk factors for syncope helps to reduce its potential risk.
2.Assessment of effectiveness of individual rehabilitation therapy in nonspecific low back pain
Kuo LI ; Chunyan ZHANG ; Yan LIU
Chinese Journal of Biochemical Pharmaceutics 2016;36(6):188-190
Objective To explore the effectiveness of individual rehabilitation therapy in patients with nonspecific low back pain.Methods A total of 50 patients with nonspecific low back pain ( NLBP) between January 2013 and January 2015 were enrolled in this study.Individual rehabilitation therapy was performed based on their different pathogenesis and risk factor of low back pain.Visual analogue score (VAS),Oswestry disability index ( ODI) and Japanese orthopaedic association ( JOA) were used for the assessment of effectiveness of individual rehabilitation therapy.Results Compared with pre-rehabilitation, VAS and ODI scores were significantly decreased at two-week after rehabilitation(P<0.05),and were further decreased at six-week after rehabilitation(P<0.01).The mean score of JOA of 50 patients before rehabilitation was (10.83 ±2.94) score,which was decreased to (24.37±7.55 )score at six-week after rehabilitation(P<0.05),with 12 patients were cured,32 were improved obviously,6 were improved moderately.The rate of efficacy was 100%.Conclusion Individual rehabilitation therapy was an effective option for NLBP,with significant decrease of pain.
3.Modifications of the hyperglycemia and stress response to open cholecystectomy following three different analgesic techniques
Chunyan YAN ; Jianguo XU ; Sihai ZHU
Chinese Journal of Anesthesiology 1996;0(09):-
Objective To compare the effect of three different analgesic techniques on hyperglycemia and stress response to cholecystotomy so as to select a more reasonable analgesic modelMethods Thirty patients after cholecystotomy ,were randomly divided into three groups using three different analgesic techniques:postoperative intravenous morphine patient-controlled analgesia(PCA)(group M),postopetative epidural PCA(group E),and pre-emptive clonidine combined with postoperative epidurral PCA(group P)Blood glucose,plasma levels of stress hormones such as cotisol,insulin,glucagon,epinephrine and norepinephrine were measured at various timesResults All three analgesic techniques produced satisfactory pain reliefHyperglycemiawas inhibited more efficiently in group E and P than in group MThe secretions of stress hormoneswere less suppressed in group M than in other two groupsThe epidural analgesics requirement in group P was lower than in group E(P
4.Diagnosis and therapy of dementia with Lewy bodies
Chunyan LIU ; Yan XING ; Yanfeng LI
Chinese Journal of Geriatrics 2017;36(4):367-370
5.Analysis on gene diagnosis results of α-thalassemia in Luzhou area
Hongying CHEN ; Chunyan LIU ; Yan ZOU
Chongqing Medicine 2014;(12):1434-1435,1438
Objective To analyze the genetic mutation patterns and the constituent ratio of α-thalassemia in Luzhou area and to investigate the clinical application value of the gene diagnosis .Methods The PCR method combined with DNA chip hybridization technique was adopted to conduct the gene detection and analysis on 116 cases of suspectedα-thalassemia .Results Among 116 sus-picious cases of α-thalassemia ,39 cases were found with genotypes of α-thalassemia ,the detection rate was 33 .62% .7 kinds of mu-tation genotypes were detected ,in which the deletion type of - -αSEA/ααaccounted for 41 .03% and the deletion type of -α3 .7/ααaccounted for 25 .64% .Conclusion The main gene mutation of α-thalassemia in Luzhou area is the deletion type of - -αSEA/αα. The gene diagnosis is an important criterion for definitely diagnosing α-thalassemia .
6.Restudy on Accounting Method of Community Health Services Cost
Chunyan XIAN ; Yan JIANG ; Wei CHENG
Chinese Health Economics 2014;(1):60-62
In order to explore more reasonable and scientific accounting method of community health service costs, to improve the accounting method system of community health service cost. In the current existing community health services costing methods, based on the analysis of hospital cost accounting methods system, analyze and imitate the accounting method of hospital costs, establish a more scientific and implemented accounting method system of community health service costs: divide parts of clinics scientifically, redesign the center acollation method of indirect cost, confirm different cost accounting methods for different cost accounting objective and provide suggestion for the improvement of project cost accounting.
7.Comparison of disinfection effect of two disinfection methods on X-ray protective clothing
Guoxing YAN ; Lixia GAO ; Shufang GUO ; Chunyan NI ; Yinghui QIN
Chinese Journal of Infection Control 2016;15(7):508-510
Objective To compare the effect of GammaTM wet wipes and 75% alcohol on the disinfection of X-ray protective clothing,and provide reference for choosing rational disinfection methods.Methods 62 pieces of X-ray protective clothing were selected,30 were from operating rooms,32 from catheterization room.Protective clothing were randomly divided into trial group and control group,each had 31 pieces.Trial group disinfected clothing with GammaTM wet wipes,control group disinfected clothing with 75% alcohol,disinfection effect,drying time,and cost between both groups were compared.Results Average bacterial colony counts in trial group and control group before disinfection were 2.38 CFU/cm2 and 2.36 CFU/cm2 respectively,qualified rates were 80.64% and 83.87%respectively.Bacteria were not detected in both groups after disinfection.The average drying time in trial group was shorter than control group([352.35±9.93]s vs[676.13±10.62]s,t=123.98,P <0.01).The cost of disinfecting X-ray protective clothing in trial group was 29.60% less than control group.Conclusion Effect of GammaTM wet wipes and 75% alcohol on disinfecting X-ray protective clothing are both reliable,compared with 75% alcohol, GammaTM wet wipes are without corrosion,have shorter drying time,and save more cost.
8.Preliminary study on changes of expressive proteome in renal tissue of chronic intermittent hypoxia rats
Chunyan ZHANG ; Ye YANG ; Yan CHEN ; Hong LI ; Chunling ZHAO
Chinese Journal of Nephrology 2011;27(8):602-605
Objective To obtain two-dimensional gel electrophoresis maps of the renal tissue proteins of normal and chronic intermittent hypoxia(CIH) rats for identifying the diferentially expressed proteins in the CIH rats.MethodsCIH rat models were established, and the proteins in the renal tissue underwent two-dimensional gel electrophoresis with immobiline pH gradientisoeleclricfocusingasthefirstdimensionandverticalSDS-PAGEasthesecond dimension.Analysis of 2-DE maps was used to determine differential expression of proteins between the two groups by ImageMaster 2D Platinum 5.0, and four protein spots expressed differently were picked up for further identification by MALDI-TOF-MS.Results Matched and compared with those of control group, 112 protein spots were determined with differently expressive levels in CIH group.By MALDI-TOF-MS, three protein spots of them were identified as ATP synthase delta subunit of mitochondrial precursor, catechol O-methyltransferase, apurinic/apyrimidinic endonudease.Conclusions There is obvious difference in expressive proteomes in renal tissue between normal and chronic intermittent hypoxia rats.The functions of those identified proteins are involved in cellular energy metabolism, apoptosis, signal transduction, anti-cell injury and hormone metabolism,so that proteomics can serve as a new approach in the study of obstructive sleep apnea-hypopnea syndrome to discover new therapeutic targets.
9.Analysis on Plasma Concentration Monitoring Data of Ciclosporin in Renal Transplantation Patients Having Survived More than Seven Years
Sulan ZOU ; Yan JIANG ; Chunyan QIAN ; Aier QIAN
China Pharmacy 2005;0(18):-
0.05), but significant difference when compared the older-age group with the young & middle-age group(P
10.Comparison of Ultrasonic Method and Continuous Reflux Extraction Process of Total Flavonoids from Radix Astragali
Fansheng KONG ; Yongguang BI ; Aiqun SUN ; Chunyan YAN
China Pharmacy 2005;0(19):-
OBJECTIVE:To compare the ultrasound method and continuous reflux extraction process of total flavonoids from Radix Astragali.METHODS:The extraction technology was optimized by orthogonal test with the content of total flavonoids of Radix Astragali as index and with the concentration of ethanol,extraction time,solid-fluid ratio,extraction temperature as factors.RESULTS:Ultrasound extraction process was superior to continuous reflux extraction process.Optimal extraction technology was as follows:the concentration of ethanol of 75%,ultrasonic extraction time of 20 min,solid-liquid ratio of 1:10,ultrasonic extraction temperature of 25 ℃ and extraction rate of 0.325%.CONCLUSION:As compared with continuous reflux extraction process,ultrasonic extraction is fast to operate,solvent saving and high extraction.