1.Related factors associated with pelvic adhesion and its influence on fallopian tube recanalization in infertile patients
Haiyan HOU ; Yaqiong CHEN ; Xiao CHEN ; Chunxiu HU ; Zhenhua YANG ; Jun CHEN ; Xiangling KONG
Chinese Journal of Obstetrics and Gynecology 2012;(11):823-828
Objective To investigate factors with pelvic adhesions and the effect of different degrees pelvic adhesions on fallopian tube recanalization in infertile patients.Methods Total of 527 infertile patients undergoing hysteroscopy and laparoscopic surgery in Affiliated Hospital of Chinese People's Armed Police Forccs Logistics College were studied retrospectively.According to the extent of pelvic adhesions,tubal umbrella adhesions and atresia,377 cases were classified into adhesion groups,including 73 cases in grade Ⅰ,221 cases in grade Ⅱ,75 cases in grade Ⅲ and 8 cases in grade Ⅳ based on adhesion score.The 150 cases with no obvious pelvic adhesion were matched as control group.Among 8 cases with grade Ⅳ ahesion were exluded from ahesion group the relationship between pelvic adhesions and related history,abdominal lesions,tubal patency and the prognosis were studied.Results(1)Related factors:the frequency of pelvic adhesion and more than 7 years of infertility of 23.9%(88/369)in adhesion group were significantly higher than 12.0%(18/150)in control groups.(2)History:compared with the control group(12.7 %,19/150;28.7%,43/150;11.3%,17/150;12.0%,18/150;17.3%,26/150),patients with pelvic adhesions present more incidence abortion(23.6%,87/369),uterine cavity operation(38.2%,141/369),ectopic pregnancy(20.9%,77/369),pelvic inflammatory disease(25.5%,94/369)and abdominopelvic surgery (31.4%,116/369).(3)Endoscopy exploration:the incidence of hydrosalpinx(24.7%,91/369),tube distorted(15.7%,58/369)and salpingostomy(72.9%,269/369)in adhesion group were higher than those in control group(2.0%,3/150;4.0%,6/150;12.0%,18/150),but relatively lower incidence of pelvic endometriosis lesions(5.7%,21/369)and mesosalpinx cysts(16.3%,60/369)than those in control group(16.0%,24/150;30.0%,45/150).The rate of proximal tubal recanalization(59.5%,91/153)in adhesion group was lower than 75.4%(52/69)in control group.However,the rate of distant tubal recanalization of 84.4%,(281/333)in adhesion group and;13/15 in control group didn't show statistical difference.(4)Prognosis:the rate of ectopic pregnancy of 9.7%(29/299)in adhesion group was significantly higher than 3.1%(4/128)in control group.Among cases with grade Ⅲ adhesion exhibited the highest rate of ectopic pregnancy(13.0%,7/54;OR =4.62,95% CI:1.29-16.50).(5)Multivariate analysis:it was found that more than two drug abortions(OR =3.29,95% CI:1.34-8.07),pelvic and (or)abdominal surgery history(OR =2.20,95% CI:1.35-3.57)and pelvic inflammatory disease history (OR =1.54,95% CI:1.21-1.97)were risk factors with pelvic adhesions.Conclusion More than or equal to two drug abortion history,pelvic inflammatory disease and pelvic and abdominal surgery damage were important factors for pelvic adhesions of infertility patients,which may decrease the possibility of proximal tubal recanalization and increase ectopic pregnancy risk.
2. Changes in quality of life and acceptance of disability of burn patients in rehabilitation treatment stage and the influencing factors
Liumei CHEN ; Lin LI ; Xiaolei WU ; Chunxiu XIAO ; Zhaohong CHEN
Chinese Journal of Burns 2019;35(11):804-810
Objective:
To explore the development trajectories of quality of life and acceptance of disability of burn patients in the rehabilitation treatment stage and the influencing factors.
Methods:
Totally 207 burn patients, including 157 males and 50 females, aged (40±13) years, who were in the rehabilitation treatment stage were selected by convenient sampling method from October 2016 to July 2017 in the Department of Burns of Fujian Medical University Union Hospital for this longitudinal study. At discharge and 1, 3, and 6 months after discharge, the patient′s quality of life and acceptance of disability were scored using the Burn Specific Health Scale-Brief and Chinese Version of Acceptance of Disability Scale-Revised respectively. Taking the intercept, the slope, and the curve slope as latent variables, the latent second growth curve model was constructed for the quality of life and the acceptance of disability. The robust maximum likelihood estimation (MLR) method was used to estimate the mean, the variance, and the covariance, so as to analyze the discharge level, the growth rate, the acceleration, and the correlation among them. Taking the acceptance of disability, the gender, the cause of burn, the severity of burn, the existence of complications, the payment way, and the education level as covariates, the latent second growth curve model was constructed for the quality of life. The MLR method was used to estimate the influence of covariates on the discharge level, the growth rate, and the acceleration of the quality of life.
Results:
At discharge and 1, 3, and 6 months after discharge, the quality of life scores of patients were (102±36), (111±36), (118±37), and (122±37) points respectively, and the acceptance of disability scores were (73±17), (75±17), (77±17), and (78±18) points respectively. The estimated mean intercept of the quality of life and the acceptance of disability were 101.680 and 72.993 respectively at discharge, both of which showed a curve increasing trend in 1, 3, and 6 months after discharge (estimated mean slope=11.024, 3.086,