1.Influencing Factors for Preoperative Anxiety Level of Elderly Patients with Prostatic Hyperplasia
Renjie LIU ; Huamao JIANG ; Chunxiu HE
Journal of China Medical University 2015;(12):1098-1101
Objective to investigate the current status of preoperative anxiety level and explore the influencing factors in elderly patients with pros-tatic hyperplasia. Methods A total of 124 patients with prostatic hyperplasia were selected for the study,and the State-trait Anxiety Inventory (StAI)was analyzed using the convenience sampling method. Results the score were 55.54±4.81 for SAI,34.60±2.09 for tAI,and 90.14±5.91 for StAI. the preoperative anxiety level of patients with prostatic hyperplasia varied in different demography(P < 0.05). According to multiple lin-ear stepwise regression equation,age,cultural level,place of residence,and the medical burden are the influence factors. Conclusion the preoper-ative anxiety level of elderly patients with prostatic hyperplasia is high,and more health education is needed. It is necessary to use different psycholog-ical persuasion according to their specific situation,so as to promote their physical and mental health,and to promote the effect of postoperative recov-ery.
2.Dust mite drops by improving immune function in treating allergic rhinitis
Chunxiu WEN ; Xiaojuan XIE ; Jinmei GAN ; Yuhua MO ; Mingjing JIANG
Chinese Journal of Immunology 2016;(2):244-246
Objective:To analyze the immune function regulation and clinical effect of dust mite drops desensitization treatment on children with allergic rhinitis.Methods:80 patients with allergic rhinitis and adenoid hypertrophy treated in our department from January 2012 to June 2014 were selected and randomly divided into experimental group and control group.Control group was treated with ebastine and levocabastine treatment, the experimental group was treated with sublingual containing Dermatophagoides Farinae Drops on the basis of control group.The level of IL-2,IL-6,house dust mite specific IgE (sIgE),dust mite IgE (T-IgE),house dust mite specific IgG4 ( sIgE in) ,blood addicted eosinophile cells ( EOS) ,and induced sputum EOS level were compared between the two groups before treatment and after 2 years treatment.Results:The level of IL-2 in the two groups was significantly higher than that before treatment,the level of IL-6 was significantly lower than that before treatment ( P<0.05 ) .After treatment, the level of IL-2 in the experimental group was significantly higher than that in the control group, the level of IL-6 was significantly lower than that in the control group( P<0.05 ).After treatment, the level of sIgE, T-IgE, blood EOS and induced sputum EOS in the two groups were significantly lower than before treatment,the level of sIgG4 were significantly higher than those before treatment (P<0.05).After the treatment,the level of sIgE, T-IgE, blood EOS and induced sputum EOS in experimental group were significantly lower than control group,and the level of sIgG4 was significantly higher than that in control group ( P<0.05).After treatment,the asthma symptom scores and nasal symptom scores of the two groups were significantly lower than before treatment (P<0.05),and those index of experimental group after treatment were significantly lower than control group ( P<0.05 ).Conclusion: Combine the basis of conventional therapy plus with Dermatophagoides Farinae Drops in the treatment of allergic rhinitis and adenoid hypertrophy children can effectively regulate the immune function of the patients,has good clinical efficacy.
3.Application of Planar Microelectrode Array Modified by Nano-structure Titanium Nitride on Dual Mode Neural Information Recording
Tingjun JIANG ; Chunxiu LIU ; Yilin SONG ; Shengwei XU ; Wenjing WEI ; Xinxia CAI
Chinese Journal of Analytical Chemistry 2014;(8):1071-1076
The nano-structure TiN was modified on the laboratory self-made planar microelectrode array pMEA by magnetron sputtering method. The performance of modified pMEA was investigated. Research on neuroelectrical and neurochemical recording was studied in vitro. The impedance of the modified pMEA was decreased almost one order of magnitude, and the background noise level was reduced to ±6 μV. In the same testing environment, the signal-to-noise ratio (SNR) of modified electrodes was 1. 7 times of bare electrodes. The SNR of neuroelectrical recording on the brain slice of SD rats reached 10:1 , and the weak signal such as ±12 μV was separated easily. For neuroelectrical recordings, the detection limit of dopamine ( DA) solution reached 50 nmol/L with the 2:1 (S/N). During the concentration range of 0. 05-100 μmol/L, the linearly correlation coefficient of the DA oxidation currents was 0 . 998 . The modification of nano-structure TiN on pMEA reduced pMEA impedance and background noise level, meanwhile the SNR was increased. The weak signals of neuroelectrical and neurochemical recording were successfully recorded.
4.Comparative study of clinical and MRI features between intracranial solitary fibrous tumor/hemangiopericytoma and meningioma
Chunxiu JIANG ; Jianbin ZHU ; Tianyu ZOU ; Xianlong WANG ; Hao YU ; Yunyan REN ; Pei GUO ; Zhibo WEN
Chinese Journal of Medical Imaging Technology 2017;33(6):848-852
Objective To investigate the MRI features of intracranial solitary fibrous tumors/hemangiopericytomas (SFT/HPC),and to compare these findings with those of intracranial meningiomas.Methods The clinical features and MRI findings in 28 patients of intracranial SFT/HPC (SFT/HPC group)and 68 patients of meningiomas (meningiomas group) confirmed by operation and pathology were retrospectively analyzed.The indicators of two groups were compared.Results Shape of tumor,signal homogeneous,signal voids of vessel in tumor,hypointense signal nodules on T2WI and enhanded,cystic or necrosis in tumor,meningeal tail sign,changes of the nearby bone,sex,Ki-67% level,blood lose in surgery had significant differences between SFT/HPC group and meningiomas group (all P<0.05).Conclusion There are some differences between intracranial SFT/HPC and meningiomas.It is helpful in diagnosis and differential diagnosis through the comparative analysis of the imaging signs.
5.Analysis in 13 315 newborns hearing screening.
Yue HUANG ; Rongjun LIANG ; Chunxiu WEN ; Jinmei GAN ; Qun LV ; Xiaoling LAN ; Mingjing JIANG ; Yuhua MO ; Xiaojuan XIE ; Xiong ZOU
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(15):1165-1167
OBJECTIVE:
Explore the model of universal NICU newborns' hearing screening in high-risk neonates, preliminary understanding factor of hearing damage.
METHOD:
Transient evoked otoacoustic emissions (TEOAE) and automatic auditory brainstem response (AABR) were used to detect newborns' hearing in 13 315 objects, that is newborns' hearing screening in NICU with TEOAE test who not pass, 42 days after will use AABR rescreening. Children's Hearing Center of Guangxi Child Health Hospital will diagnose the newborns that did not pass in 3 months.
RESULT:
In these 13 315 newborns, 5 151 subjects who did not pass the initial screening, 1910 subjects who also did not pass after 42 days, 1167 subjects cannot pass the rescreening after 3 months, 642 subjects were diagnosed congenital hearing impairment by Brainstem Auditory Evoked Potential Test, the rate is 4.82%.
CONCLUSION
TEOAE and AABR are the suitable model of universal newborns' hearing screening in high-risk neonates.
Evoked Potentials, Auditory, Brain Stem
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Female
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Follow-Up Studies
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Hearing Tests
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Humans
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Infant, Newborn
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Intensive Care Units, Neonatal
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Male
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Neonatal Screening
6.CT and MR imaging diagnosis of intracranial teratomas
Jingwen WU ; Xianlong WANG ; Yanhong LIN ; Lyujin FENG ; Chunxiu JIANG ; Zhibo WEN
Chinese Journal of Neuromedicine 2015;14(9):890-893
Objective To analyze the CT and MR imaging features of intracranial teratomas to improve the diagnostic accuracy.Methods Twenty patients with intracranial teratomas,admitted to and performed surgery in our hospital from January 2010 and January 2014,were chosen;the teratoma was confirmed by histopathology.The CT and MR imaging features,clinical and pathology materials of these patients were retrospectively analyzed.Results Twelve immature teratomas,7 mature teratomas and one teratoma with malignant transformation were noted;18 patients were in the central line area and 2 were not.In the 9 patients performed CT scan,7 showed heterogeneous mass;peritumoral calcification was more common than intratumoral calcification,and it turned out to be round with diameter less than 1 cm,while intratumoral calcification was multifocally strip and patchy.In the 17 patients performed MR imaging,14 showed heterogeneous signal and fatty signal was detected in 3;enhanced MR imaging showed that 6 presented nodular enhancement,3 presented multilocular enhancement markedly,patchy enhancement showed in 2,and one showed marked enhancement in mural nodule and cystic wall.In 8 patients performed diffusion-weighted imaging,7 displayed hypointense to isointense and one demonstrated isointense to hyperintense.Conclusions Intracranial teratoma has some characteristic imaging features,so by combining clinical materials,it should be considered when fatty component is detected in a heterogeneous intensity tumor with multiple cystic change,calcification and a hypointense to isointense signal on DWI;however,pathology is needed to make a definite diagnosis.