Objective To compare the effects of no-rinse skin cleanser and warm water with paraffin oil in first brush bath of the new-born. Methods About 42 newborns who were born from January to March 2016 were set as control group and used warm water with paraffin oil in first brush bath. About 43 newborns who were born from April to June 2016 were set as observation group and used no-rinse skin cleanser in first brush bath. The cleaning time and effect ,the rectal temperature before and after sponge and dermatitis were compared. Results Both groups did not develop dermatitis. But the observation group had better cleaning satisfaction , less cleaning time, faster rewarming than those of the control group with statistical significance (all p<0.05). Conclusion No-rinse skin cleanser used in the first brush for the new-born can reduce cleaning time and difference of temperature, which is safe for clinical application.

Objective To explore the application effect of early warning scoring system in condition evaluation of high risk neonates. Methods 120 high-risk neonates born in our hospital were selected as observation group and 150 normal newborns in the same period as control group. Early warning scoring system and children′s early warning score system were conducted to both groups, and the results were compared.Results In the early warning scoring system, frequency of breath, cardiac rhythm, respiratory distress, and lethargy/coma in the observation group was significantly higher than that in the control group ( P<0.05);but body temperature showed no apparent change in both groups (P>0.05); early warning scores of 105 neonates in the observation group were not lower than 2 points, with the most going to respiratory diseases, sepsis, congenital heart disease and unexplained seizures;in the two scoring systems, scores of sensitivity, Youden index, negative predictive value and positive predictive value were significantly different ( P<0.05); specificity of the two groups showed no obvious contrast (P>0.05); area under the curve showed obvious difference between the two groups (P<0. 05) . Conclusions Early warning scoring system can evaluate effectively condition changes of high-risk neonates, reflect accurately their severity, and has fine flexibility and operability. It is worth promoting in clinic.

We report a critically ill pregnant woman in the third trimester with severe pneumonia due to COVID-19 who presented to Xiaolan People's Hospital of Zhongshan in February 2020. The 32-year-old patient was admitted at 35 +2 gestational weeks with a 4-day history of a sore throat and a fever for three hours. The patient had been to Xiaogan City, Hubei Province, and the symptoms occurred during a period of self-isolation after back home. The condition of the patient deteriorated rapidly, with left-sided chest and back pain, shortness of breath, dizziness, progressing to respiratory failure and septic shock 7 hours after her admission. In view of her critical condition and a history of two previous cesarean sections, an emergency cesarean section was performed. Blood gas analysis of the mother before the operation suggested respiratory failure, respiratory acidosis, and metabolic acidosis. During the operation, a baby boy was born. The Apgar score of the boy, birth weight of 2 700 g, was one at 1, 5 and 10 minutes despite the resuscitation efforts. The neonate died after withdrawing treatment. The patient was treated with tracheal intubation ventilator and other supportive treatments after the operation. The result of the new coronavirus nucleic acid test, taken on admission, but which was reported after delivery, was positive. The patient was transferred to the designated hospital for further treatment and was recovering with the withdrawal of extracorporeal membrane oxygenation and ventilation support at 26 and 36 days after surgery, respectively.