Objective To explore the role of probiotics in the prevention of diarrhea in critically ill patients.Methods The patients receiving enteral nutrition from May 2009 to September 2010 in the Respiratory Intensive Care Unit were divided into routine feeding group (control group,n =38) and probiotic yogurt feeding group (yogury group,n =42).The control group accepted routine enteral nutrition liquid (Nutrison),while the yogurt group accepted conventional feeding plus probiotic yogurt.The incidence of dianhea,length of hospital stay,and other indicators were compared between these two groups.Results The incidence of diarrhea was lower in the yogurt group on the 5th,6th,and 7th days (P＜0.05).The cases of positive stool bacterial and fungal culture results in the yogurt group were less than those in the control group (P ＜ 0.05).In addition,the hospital stay was shorter [(13.17±3.79) d vs.(15.18±4.39) d,P=0.031],the cost was lower [(6307±2358) yuan vs.(8253±3186) yuan,P =0.002],and the satisfaction of the patients were higher in the yogurt group.Conclusion Probiotics may reduce the occurrence of diarrhea associated with enteral nutrition in critically ill patients.

Chitosan-carboxymethyl-chitosan complex film was prepared by freeze drying. Some tests in vivo and in animal were employed, in order to evaluate it on biology. All results indicated that the film has not only good surface compatibility but also good structural compatibility. It can be more suitable for GTR technology.
Animals ; Biocompatible Materials ; chemical synthesis ; pharmacology ; Chitin ; analogs & derivatives ; Chitosan ; Materials Testing ; Membranes, Artificial ; Rabbits ; Rats ; Skin Irritancy Tests