Objective To observe the effect of different doses of simvastatin in the treat-ment of acute myocardial infarction,and to explore the nursing countermeasures.Methods A total of 86 patients with acute myocardial infarction in our hospital were as the research objects,and were randomly divided into 2 groups,and all the patients used simvastatin on the basis of conventional treatment.A group with 43 cases was given simvastatin dosage for 20 mg,B group with 43 cases was given simvastatin dosage for 40 mg.Both 2 groups during the treatment were given comprehen-sive nursing intervention.The treatment effect of 2 groups was compared.Results After treat-ment,the total efficiency in A group was 95.4% and 81.4% in B group,the difference in the total efficiency between 2 groups was significant (P <0.05).Before treatment,there was no significant difference in TC,TG,LDL-C and CRP (P >0.05)and the index of group B after the treatment was better that that in the A group (P < 0 .0 5 ).The incidence rate of cardiovascular events was 25.6% in A group and 9.3% in B group,and the incidence rate of cardiovascular events in B group was significantly less than that that in A group (P <0.05).Adverse reaction rate was 11.6% in A group and 16.3% in B group,there was no significant difference between 2 groups (P >0.05). Conclusion The curative effect of higher dose simvastatin in adjuvant treatment of acute myocar-dial infarction is better and it can reduce cardiovascular adverse events,so it is worthy of applica-tion.

Objective To observe the effect of different doses of simvastatin in the treat-ment of acute myocardial infarction,and to explore the nursing countermeasures.Methods A total of 86 patients with acute myocardial infarction in our hospital were as the research objects,and were randomly divided into 2 groups,and all the patients used simvastatin on the basis of conventional treatment.A group with 43 cases was given simvastatin dosage for 20 mg,B group with 43 cases was given simvastatin dosage for 40 mg.Both 2 groups during the treatment were given comprehen-sive nursing intervention.The treatment effect of 2 groups was compared.Results After treat-ment,the total efficiency in A group was 95.4% and 81.4% in B group,the difference in the total efficiency between 2 groups was significant (P <0.05).Before treatment,there was no significant difference in TC,TG,LDL-C and CRP (P >0.05)and the index of group B after the treatment was better that that in the A group (P < 0 .0 5 ).The incidence rate of cardiovascular events was 25.6% in A group and 9.3% in B group,and the incidence rate of cardiovascular events in B group was significantly less than that that in A group (P <0.05).Adverse reaction rate was 11.6% in A group and 16.3% in B group,there was no significant difference between 2 groups (P >0.05). Conclusion The curative effect of higher dose simvastatin in adjuvant treatment of acute myocar-dial infarction is better and it can reduce cardiovascular adverse events,so it is worthy of applica-tion.