1.Clinical observation of persimmon leaf extract on secondary prevention of ischemic cerebrovascular disease
Xuecai ZHOU ; Chunqin PAN ; Mei GAO
Chinese Journal of Biochemical Pharmaceutics 2015;37(4):112-115
Objective To investigate persimmon leaf extract on secondary prevention of ischemic cerebrovascular disease, and the impact on blood pressure, blood sugar, blood lipid, hemorheology, blood rheology indexes and blood homocysteine levels in patients with ischemic cerebrovascular disease.Methods 200 cases of patients with ischemic cerebral vascular disease were chosen, which were randomly divided into observation group and control group with 100 cases in each group.Both of the groups were given conventional therapy.And the observation group received persimmon leaf extract intervention.Then the rate of recurrence of ischemic cerebrovascular disease was observed after 3 months and 6 months.At the same time, the indexes of blood pressure and blood sugar, blood lipid, hemorheology, blood flow and blood homocysteine were recorded and compared in the second morning after being selected and after 3 months and 6 months treatment.Results After treatment for 3 months, the recurrence rate of observation group was 4.40%, 3.70% of control group; after treatment for 6 months, 8.24% of observation group, 13.75% of control group, and there were no significant differences between two groups of recurrence of ischemic cerebrovascular disease.After 6 months, systolic and diastolic blood pressure in both groups were lower than before treatment.and they were lower in observation group than control group (all P<0.05).After 3, 6 months, TC, TG, LDLC levels decreased and HDLC increased compared with before treatment, and the above indexes improved more in observation group than control group (all P<0.05).After 3, 6 months, FBG, 2hPG, HbA1C levels decreased compared with before treatment, and the above indexes decreased more at the same time point in observation group than control group (all P<0.05).After 3, 6 months, HCY levels decreased compared with before treatment, and HCY decreased more at the same time point in observation group than control group ( all P<0.05 ).After 6 months, blood rheology indexes levels improved more compared with before treatment, and they improved more at the same time point in observation group than control group (all P<0.05).After 6 months, main artery blood flow velocity levels increased compared with before treatment, and they increased more at the same time point in observation group than control group ( all P<0.05 ) .Conclusion Persimmon leaf extract intervention therapy can effectively improve blood pressure , sugar, lipid, hemorheology, homocysteine and prevent platelet aggregation and thrombosis.
2.A Research on the Social Support and the Quality of Life of Renal Transplant Patients
Chunqin ZHOU ; Ni WANG ; Yuhong LIU
Chinese Medical Ethics 1996;0(01):-
Objective: To explore the effect of social support in increasing the quality of life of renal transplant patients by investigating social support and quality of life of renal transplant patients in our hospital.Methods: The patients after renal transplantation more than 3 months were questioned randomly in clinic using the rating scales of SSRS and WHOQOL ~BREF.Results: It showed high social support in patients after renal transplantation,but there was dangerous of low social support in young female.The score of quality of life and physiological domain was lower than routine model.There were not significant differences in the psychological,social and surrounding domains of renal transplant patients compared with the routine model.There was a significantly positive relationship between social support and quality of life of renal transplant patients(P
3.The Study About Carrying ISO9000series Standard out and Improving the Work Quality in Oprating Room
Ni WANG ; Chunqin ZHOU ; Pinli LI
Chinese Medical Ethics 1995;0(02):-
Objective:to detect the effect of working qulity in operating room before and after apply ISO9000 series standard.Methods:the questionnaire of the satisfaction comes from the patients to the nurses of the operating room,the examine score chart to the instrumental nurses in the operating room,the examine score chart to the circulating nurse of operating room as the 3 measuring scale to be investigated as the comparation about the effect of the application of the ISO9000 standard.Results:①The degree of the patients satisfation is improved to such an extent after the ISO9000 standards applied.②The checking result of the instrumental nurses and the circulating nurses is also of the obvious difference;what is more,once the nursing matron published the specific checking standards and the checking result,it is liable to the nurses to realize their own faults.③Through this period of the investigation and the research,the application of the ISO9000 quality managing architecture better formalize the nurses work than before,everything is equipped with foundation and standard,thus the working quality is improved.
4.Study on the Quality Standard for Fufang Ningshen Granule
Yang HUANG ; Wenyi ZANG ; Chunqin MAO ; Tulin LU ; Yaping ZHOU
China Pharmacy 2016;27(30):4285-4287
OBJECTIVE:To establish the quality standards for Fufang ningshen granule. METHODS:TLC was used for the qualitative identification of Radix angelicae and White paenoy;HPLC was adopted for the contents determination of spinosin and verbascoside:the column was Kromasil C18 with the mobile phase of acetonitrile-0.1% acetic acid(16∶84,V/V)at a flow rate of 1.0 ml/min,detection wavelength was 330 nm,column temerpature was 30 ℃. RESULTS:The TLC spots of R. angelicae and W. pae-noy were clear with good separation,negative control without interference. The linear range was 0.055 44-0.277 2μg for spinosin(r=0.999 4)and 0.055 98-0.279 9 μg for verbascoside(r=0.999 5);RSDs of precision,stability and reproducibility tests were lower than 3.0%;recoveries were 95.62%-100.53%(RSD=1.77%,n=9) and 95.63%-102.57%(RSD=2.74%,n=9). CONCLU-SIONS:The standard can be used for the quality control of Fufang ningshen granule.
5.Effects of labor analgesia on maternal and neonatal outcome by epidural low concentration of bupivacaine combined with anisodamine
Xiaoli YANG ; Chunqin ZHOU ; Xiaogang LI ; Xiaodong SHEN ; Yuliang ZOU
Journal of Pharmaceutical Analysis 2008;20(4):278-281
Objective To observe the effects of labor analgesia on maternal and neonatal outcome by epidural application of 0.125% bupivacaine combined with anisodamine on the labor stage, and modes of delivery and neonatal Apgar's score. Methods A total of 220 primiparaes with full-term pregnancy, monocyesis and fetal head presentation without any obstetrical or systematic complications were chosen and divided into analgesic group and control group (110 in each group). The mixture of bupivaeaine and anisodamine was injected into the epidural space of the parturients in the analgesic group while those patients in the control group did not receive any analgesics. Results The analgesic effect was satisfactory (91.8 %), and no side effects occurred in the second stage of labor. The instrument delivery rate was lower in the analgesic group, and there was no significant difference between the two groups in neonatal Apgar's score. Conclusion The method is feasible in clinic for labor pain relief without increasing the rate of dystocla and complications of delivery.
6.Effects of nurse-led discharge planning on discharge readiness and ostomy psychological adaptation in patients with enterostomy
Yanping DONG ; Ping ZHOU ; Lihong WU ; Yueqiu SHI ; Chunqin ZHU
Chinese Journal of Practical Nursing 2022;38(1):25-31
Objective:To investigate the intervention effects of nurse-led discharge planning on discharge readiness and ostomy psychological adaptation in patients with enterostomy.Methods:A total of 70 patients with enterostomy admitted from January 2019 to October 2020 in Jiangsu Province Hospital of Chinese Medicine were enrolled in the present study. They were assigned to experimental group and control group according to the admission time, there were 35 cases in each group. There was one case lost in the control group in the end. The control group received the routine care, while the experimental group implemented nurse-led discharge planning. The Chinese version of Readiness for Hospital Discharge Scale (RHDS) and Ostomy Adjustment Inventory (OAI) were adopted as indicators, the intervention effects was compared between the two groups.Results:On discharge, disease knowledge, coping ability, personal status and expected support dimension scores and total scores in RHDS were (58.06 ± 12.54) , (23.57 ± 3.73), (24.29 ± 3.48) , (30.40 ± 5.25), (136.31 ± 14.32) points in the experimental group, which were significantly higher than those in the control group (49.57 ± 13.28), (18.63 ± 4.97), (22.37 ± 4.28), (26.11 ± 5.66), (101.68 ± 13.04) points, and the differences were statistically significant ( t values were 2.05-4.91, all P<0.05) . On discharge and 1 month after discharge, the persistent worry, acceptance, positive attitude towards life dimension scores and total scores in OAI were (21.34 ± 2.72) , (13.29 ± 2.36), (15.26 ± 3.24), (49.89 ± 5.70) points and (22.03 ± 3.45), (12.49 ± 3.10), (15.09 ± 3.06), (49.60 ± 5.55) points in the experimental group, which were significantly higher than those in the control group (19.35 ± 2.98) , (11.56 ± 2.79), (13.26 ± 3.15), (44.18 ± 5.63) points and (19.91 ± 3.34), (10.76 ± 2.80), (12.24 ± 3.25), (42.91 ± 4.76) points, the differences were statistically significant ( t values were 2.42-5.36, all P<0.05). Conclusions:Nurse-led discharge planning can promote discharge readiness and ostomy psychological adaptation in patients with enterostomy.
7.Real emotional experience of subjective well-being of elderly people in nursing homes during the COVID-19 pandemic
Dongyi LUO ; Ying ZHOU ; Xiaofang ZOU ; Yao HUANG ; Gangna ZHANG ; Chunqin LIU ; Jiani CHEN ; Qiulin BI
Chinese Journal of Practical Nursing 2022;38(30):2361-2367
Objective:To describe the real experience of the elderly who has felt happy during the time they stayed at nursing homes, and discuss the meaning which is behind their experience during the COVID-19 pandemic, to provide scientific basis for improving their subjective well-being.Methods:Qualitative explanatory phenomenological analysis methods, and semi-structured in-depth interviews were used to interview 21 elderly people living in Guangzhou Songhe Nursing Home. Data analysis and subject extraction were carried out with reference to the Colaizzi 7-step analysis.Results:The real experience of subjective well-being of the elderly in nursing homes has six themes: be satisfied with the nursing home management service, be satisfied with harmonious interpersonal relationship, be satisfied with good health, be satisfied with family support, grateful and expectations for the social support system, be satisfied with and grateful for the epidemic prevention work during the COVID-19 epidemic.Conclusions:The elderly who live in a nursing home with perfect management and service, care for each other, are healthy, receive family and social support, are grateful, and understand family and social support will be more likely to feel happy. Improving the subjective well-being of the elderly in nursing homes requires the coordination and support of nursing homes, the elderly, families, society and other aspects.