Objective:To explore the predictive efficiency of the timed "up and go" test (TUGT) on the frailty of elderly inpatients with cardiovascular disease and to provide an objective reference for clinical assessment of frailty.Methods:According to the convenience sampling method, a total of 156 elderly patients who were hospitalized in Cardiovascular Department in the Second Affiliated Hospital of Shantou University Medical College from May to July 2019 were selected as research objects. Frailty Phenotype Scale was used to evaluate their frailty, TUGT was used to record their walking function and ROC was used to analyze the predictive efficiency of TUGT on the frailty of elderly inpatients with cardiovascular disease.Results:ROC curve analysis showed that the optimal critical value of TUGT for predicting frailty of patients aged 60 to 69 years was 15.17 s, area under curve ( AUC) was 0.827, 95% CI was 0.727 to 0.902, the sensitivity was 66.67% and the specificity was 98.04%. The optimal critical value of TUGT for predicting frailty of patients aged equal or over to 70 years was 15.26 s, AUC was 0.829, 95% CI was 0.724 to 0.906, the sensitivity was 77.50% and the specificity was 82.86%. Conclusions:TUGT has moderate predictive efficacy in assessment of frailty in elderly inpatients, but it can provide an objective and effective reference for clinical data. Moreover, the test is fast, simple and clinically easy to operate, which can be used as a preliminary screening for frailty in elderly inpatients with cardiovascular diseases.