Objective To explore the application value of dynamic vascular patterns(DVP) curve and parameter figure in the focal liver lesions by contrast-enhanced ultrasound(CEUS).Methods 83 cases of focal liver lesions diagnosed by pathologically or clinically that had undergone CEUS were analyzed by SonoLiver software.Then DVP parametric images were constructed and the time-intensity curve (TIC) parameters were calculated by TIC and DVP curve.Results Rise time(RT),time to peak(TTP),maximum intensity(IMAX),mean transit (mTT),slope of rise,and the absolute value for slope of half down between malignant and benign lesions groups indicated statistically significant difference (P ＜0.05).94.9％ of type Ⅰ was malignant lesions and 100％ Ⅳ type was benign lesions.The four types of DVP curve(Ⅰ,Ⅱ,Ⅲ,Ⅳ)in malignant and benign lesions were 72.5％,13.7％,13.7％,0 and 6.2％,43.8％,31.2％,18.8％,respectively.The proportion and characteristic of DVP parametric images and DVP curves in malignant and benign lesions groups were consistent.Conclusions DVP curve and parametric images of CEUS can demonstrate the difference of flow perfusion static between lesions area and surrounding liver parenchyma dynamically and directly.These are new qualitative indexes of the differential diagnosis in focal liver lesions.

Objective To describe body mass index (BMI) changes in migrant children with overweight and obesity in Beijing treated by the exercise and dietary intervention programme.Methods BMI was assessed at before and after the intervention in 30 migrant obesity and overweight children aged 9 ～ 12 in two schools from March,2010.Results BMI reduced significantly one week after the intervention ( P ＜ 0.05 ),but from two months to six months after the intervention BMI increased again to the pretreatment level( P ＜ 0.05 ).Conclusion The intervention was successful in decreasing BMI,however maintenance of BMI after treatment was not easy.The controlling of obesity and overweight is a long term process which needs the cooperation and supervision of their parents.

AIM:To study the influence of angiotensin Ⅱ(AngⅡ) on ATP-binding cassette transporter A1 in THP-1 derived foam cells.The variance of the expression of ABCA1,the content and the effluent rate of cholesterol were also investigated.METHODS: The regulatory effect of AngⅡ on the expression of ABCA1 mRNA and protein in THP-1 derived form cells were measured by RT-PCR and Western blotting.The effect of variance of cholesterol content was measured by zymochemistry via-fluorospectrophotometer,cholesterol effluent was measured by liquid scintillator.RESULTS: A positive facilitative effect of Ang Ⅱon form cells was observed.Total cholesterol content were increased significantly by Ang Ⅱ treatment(P

Objective To explore the best approach to treatment of cesarean scar pregnancy (CSP). Methods A total of 138 patients with CSP treated between January and December, 2013 were retrospectively analyzed. The patients were treated with conservative drug therapy, direct curettage, uterine curettage after embolization, or open or transvaginal surgery. The amount of blood loss, proportion of patients with blooding loss greater than 50 mL, hospitalization days, and hospitalization expenses were compared among the groups. Results The median volume of blood loss was 370 mL in the conservative treatment group, 59 mL in direct curettage group, 67 mL in interventional therapy group, and 1425 mL in the surgical group, and the proportion of patients with blood loss over 50 mL was 76.9%, 38.8%, 27.5%, and 100%in the 4 groups, respectively. The midian hospital stay of the 4 groups was 9.0, 4.0, 6.0 and 10.0 days, with median hospitalization expenses of 12281.0, 3843.5, 14805.0, and 17202.2 RMB Yuan, respectively. All these data were significantly different among the 4 groups (P<0.05). Conclusions Direct curettage surgery should be encouraged for treatment of CSP. Embolization therapy can reduce the risk of bleeding but is associated with potential complications and more costly, and should be performed with caution. Open or trasnvaginal surgery can be considered in difficult cases of CSP, and its combination with interventional therapy is an option to better preserving the uterus.

Objective To explore the best approach to treatment of cesarean scar pregnancy (CSP). Methods A total of 138 patients with CSP treated between January and December, 2013 were retrospectively analyzed. The patients were treated with conservative drug therapy, direct curettage, uterine curettage after embolization, or open or transvaginal surgery. The amount of blood loss, proportion of patients with blooding loss greater than 50 mL, hospitalization days, and hospitalization expenses were compared among the groups. Results The median volume of blood loss was 370 mL in the conservative treatment group, 59 mL in direct curettage group, 67 mL in interventional therapy group, and 1425 mL in the surgical group, and the proportion of patients with blood loss over 50 mL was 76.9%, 38.8%, 27.5%, and 100%in the 4 groups, respectively. The midian hospital stay of the 4 groups was 9.0, 4.0, 6.0 and 10.0 days, with median hospitalization expenses of 12281.0, 3843.5, 14805.0, and 17202.2 RMB Yuan, respectively. All these data were significantly different among the 4 groups (P<0.05). Conclusions Direct curettage surgery should be encouraged for treatment of CSP. Embolization therapy can reduce the risk of bleeding but is associated with potential complications and more costly, and should be performed with caution. Open or trasnvaginal surgery can be considered in difficult cases of CSP, and its combination with interventional therapy is an option to better preserving the uterus.

OBJECTIVETo explore the best approach to treatment of cesarean scar pregnancy (CSP).

METHODSA total of 138 patients with CSP treated between January and December, 2013 were retrospectively analyzed. The patients were treated with conservative drug therapy, direct curettage, uterine curettage after embolization, or open or transvaginal surgery. The amount of blood loss, proportion of patients with blooding loss greater than 50 mL, hospitalization days, and hospitalization expenses were compared among the groups.

RESULTSThe median volume of blood loss was 370 mL in the conservative treatment group, 59 mL in direct curettage group, 67 mL in interventional therapy group, and 1425 mL in the surgical group, and the proportion of patients with blood loss over 50 mL was 76.9%, 38.8%, 27.5%, and 100% in the 4 groups, respectively. The midian hospital stay of the 4 groups was 9.0, 4.0, 6.0 and 10.0 days, with median hospitalization expenses of 12281.0, 3843.5, 14805.0, and 17202.2 RMB Yuan, respectively. All these data were significantly different among the 4 groups (P<0.05).

CONCLUSIONDirect curettage surgery should be encouraged for treatment of CSP. Embolization therapy can reduce the risk of bleeding but is associated with potential complications and more costly, and should be performed with caution. Open or trasnvaginal surgery can be considered in difficult cases of CSP, and its combination with interventional therapy is an option to better preserving the uterus.

Cesarean Section ; adverse effects ; Cicatrix ; complications ; Curettage ; Female ; Humans ; Length of Stay ; Pregnancy ; Pregnancy, Ectopic ; drug therapy ; etiology ; surgery ; Retrospective Studies ; Treatment Outcome ; Uterine Artery Embolization ; Uterus ; surgery

Objective:To investigate the status quo of patient privacy protection behavior of clinical nurses and analyze its influencing factors.Methods:Using the convenient sampling method, clinical nurses from tertiary hospitals in China were selected to conduct a questionnaire survey on from March to April 2018. The Chinese version of Patient Privacy Scale (PPS) were used to conduct an investigation through Questionnaire Star electronic questionnaire. A total of 1, 043 valid questionnaires were collected, and the effective response rate was 100%.Results:The PPS total score of 1 043 clinical nurses was (124.86±12.16) . The item with the highest score was "You would use screens, curtains and sheets to protect patients' privacy when necessary" (4.89±0.39) , while the item with the lowest score was "You would knock on the door before entering the patient's room and enter after asking for the patient's consent" (4.11±1.14) . The results of multiple regression analysis showed that education level and department had effects on patients' privacy protection behavior ( P<0.05) . Conclusions:The patient privacy protection behavior of clinical nurses is generally at a good level, but there is still room for improvement in individual behaviors. Teaching hospitals should strengthen education related to patient privacy protection for nurses with higher education degree who undertake teaching tasks and nurses in surgical monitoring departments and formulate specific relevant teaching procedures and detailed rules.

The expression of stretch-activated potassium channel TREK-1 mRNA and protein of hypertrophic myocardium was measured. Using a model of hypertrophy induced by coarctation of abdominal aorta in male Wistar rats, the expression of TREK-1 mRNA and protein was detected by using semi quantitative RT PCR and Western blot respectively. At 4th and 8th week after constriction of the abdominal aorta, rats developed significant left ventricular hypertrophy. As compared to sham operated group, stretch activated potassium channel TREK-1 mRNA was strongly expressed and protein was up regulated in operation groups (P＜0.05). It was concluded that the expression of TREK 1 was up regulated in hypertrophic myocardium induced by chronic pressure overload in Wistar rats.

Objective To investigate the effects of olanzapine combined with metacognitive training on social cognition and insight of schizophrenic patients.Methods One hundred twenty patients with schizophrenia were randomly divided into two groups. All patients received four week treatment. The study gr oup received olanzapine combined metacognitive training treatment and the control group only used olanzapine treatment. The positive and negative symptoms scale (PANSS), the Insight and Treatment Attitude Questionnaire (ITAQ), the Beck Cognitive Insight Scale (BCIS) and Faux Pas Recognition Task (FPRT) were assessed at baseline and after four weeks of treatment. Result There was no statistically significant difference in the scores of all battery between two groups before treatment (P>0.05). the scores of total PANSS and subscales, ITAQ, BCIS and FPRT were statistically significant between study and control groups (P<0.05).After 4 weeks of treatment,the total PANSS scores and subscales scores were significantly lower in the study group than in the control group (P<0.05). The ITAQ score, self-reflection factor of BCIS, composite index and FPRT scores were significantly higher in the study group than in the control group (P<0.05). The difference in self-certainty of BCIS difference was not statistically significant(P>0.05).Differences of the remaining scales were statistically significant(P<0.05). Conclusion Olanzapine combined with metacognitive training has a significant effect on the social cognitive dysfunction in schizophrenic patients,improving the patient's insight and enhancing the social function.

Objective To understand obstetrical nurses′awareness and attitude to breastfeeding in patients with hepatitis B in level three class A hospitals in Beijing,so as to provide references for scientific guidance and increase of breastfeeding rate in this special population in the future.Methods Using convenience sampling method,questionnaires were delivered in 1 86 obstetrical nurses from 7 level three class A hospitals in Beijing,in order to investigate their awareness on whether patients with hepatitis B could feed infants with breast milk,and their attitude toward breastfeeding of patients with hepatitis B.Results A total of 1 86 obstetrical nurses were surveyed,of whom only 64.6% could correctly answer breastfeeding-related problems about patients with hepatitis B.82.3% of the surveyed obstetrical nurses falsely thought that level of HBV DNA titer in breast milk would affect breastfeeding.Only 29.6% of the surveyed nurses were aware of Clinical Guideline on Prevention of Mother-to-child Transmission.When surveying about their willingness,only 45.2% of the nurses supported the breastfeeding of patients with hepatitis B.Differences were statistically significant among nurses on their awareness and attitude toward whether newborn infants could be fed by breast milk from patients with hepatitis B after receiving immune block,and on whether the nurses would encourage puerperas with hypatitis B to feed their infants by breast milk when they were consulted by these puerperas.Conclusions Hospital and department managers should pay increasing attention to learning and awareness of new knowledge and new technologies of obstetrical nursing staff,by implementing continuing education,enhancing their acceptance of self-worth and their confidence in self knowledge level,so as to provide more scientific,accurate and effective health education for maternal and child safety.