1.Analysis of metastatic adrenal carcinomas missed diagnosis.
Xiaodong XIE ; Chunjing XING ; Fulin SONG
Chinese Journal of Practical Internal Medicine 2001;0(10):-
Objective To improve the diagnosis of metastatic adrenal carcinomas. Methods 123 cases of primary canc-er which had been proved by autopsy in recent 10 years were reviewed. 23 cases of metastatic adrenal carcinomas werefound in all cases,the metastatic being unilateral in 20 and bilateral in 3. Results All the 23 cases of metastatic adrenal-carcinomas had been found missed diagnosis. Conclusion 16 cases are from lung cancer,among which 8 cases are smallcell lung cancer. It is important to prevent metastatic adrenal carcinomas from small cell lung cancer.
2.Preparation and characterization of multi-functional targeting nano-carrier based on pH-redox tumor microenvironment
Jingfang SUN ; Chunjing GUO ; Yunduan ZHANG ; Xiaoyan SONG ; Jiantao LYU ; Jungang YIN ; Daquan CHEN
Journal of China Pharmaceutical University 2017;48(3):305-310
In order to construct a novel multifunctional targeting nano-carrier based on pH-redox characteristics of tumor microenvironment,ketone bonds and disulfide bonds were bonded to the oligomeric hyaluronic acid (oHA) being sensitive to pH and the reduction environment.The chemical structure of oligomeric hyaluronic acid-8-mercaptomenthone 1,2-glycerolketal (oHMST) was characterized by 1H NMR,IR and ESI-MS.Curcuminloaded micelles were prepared by dialysis.The single factor investigation was carried out on the dosage form.Some properties,including particle size zeta potential,the morphology of micelles,and pH-sensitivity were studied.The materials were synthesized successfully.The micelles were spheric with a diameter of about 100 nm.The Zeta potential of the micelles was-(21.97 ± 1.08) mV.The in vitro test showed that oHMST carriers have good pH-sensitivity and redox-sensitivity.
3.Microwave thermoacoustic signal analysis of biological tissues based on the coupling of multifield.
Chunjing TAO ; Tao SONG ; Guoqiang LIU ; Jing YAN
Journal of Biomedical Engineering 2008;25(1):44-48
According to the coupling relationship of electromagnetic field, thermal field and acoustic field during the time that microwave irradiates the biological tissues, we conducted a study on the microwave-induced thermoacoustic tomography forward problem. In the study, we started from the thermoacoustic wave propagation that incorporated the spatial inhomogeneities of thermal and acoustic properties, and we used a method based on the finite element to solve the thermoacoustic equation. As the penetration depth and the specific absorption rate changed with the microwave frequency in biological tissue, the hotspot position and value altered, so the pressure wave propagation and the detecting value would be influenced. By analyzing the simulation results, we found that different detection point has different information content. Because the microwave-induced acoustic waves contain abundant information about the structural, electromagnetic and acoustic properties of phantom, they can reflect information on the tissue composition and structure of the phantom effectively.
Acoustics
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instrumentation
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Adipose Tissue
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anatomy & histology
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Biophysical Phenomena
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Humans
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Microwaves
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Muscle, Skeletal
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anatomy & histology
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Signal Processing, Computer-Assisted
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Thermography
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methods
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Tomography
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instrumentation
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methods
4.Experiment and analyse on the effect of magnetic nanoparticles upon relaxation time of proton in molecular recognition by MRI.
Lili HU ; Tao SONG ; Wenhui YANG ; Ming WANG ; Fang ZHANG ; Chunjing TAO
Journal of Biomedical Engineering 2007;24(3):590-614
To research on the effect of three different magnetic nanoparticles upon relaxation time of proton. The detection by magnetic resonance imaging (MRI) indicates that there is the effect of marked difference to right control experiment and to analyze the difference from theory. The result discloses that will be able to perform the experiment of molecular recognition using magnetic nanoparticles later.
Ferric Compounds
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chemistry
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Humans
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Magnetic Resonance Imaging
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instrumentation
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methods
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Magnetic Resonance Spectroscopy
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methods
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Magnetics
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Nanoparticles
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Protons
5.Effect of rehabilitation bridging mode on postoperative functional exercise in patients with breast cancer
Xiaoming FANG ; Ping SONG ; Sheng LI ; Chunjing LYU ; Fuyun ZHAO
Chinese Journal of Practical Nursing 2023;39(36):2815-2819
Objective:To explore the effect of functional exercise rehabilitation bridging mode on the functional exercise and self-management ability of patients after breast cancer surgery, so as to provide reference for guiding patients to achieve full process management and self-management and rehabilitation.Methods:Using a non randomized grouping quasi experimental design, 202 patients with breast cancer undergoing surgical treatment were selected from the breast surgery department of Yuhuangding Hospital in Yantai from March to July 2021 through convenient sampling. The control group received routine nursing and rehabilitation guidance. The intervention group adopted a rehabilitation bridging mode for postoperative functional exercise on the basis of routine nursing care. The functional exercise compliance rate and self management ability of the two groups of patients after the intervention were evaluated.Results:In the intervention group, the rate of functional exercise reaching the standard, the rate of functional exercise knowledge awareness, correctness and compliance in self-management ability of breast cancer patients were as follows: 93.1%(95/102), 71.6%(73/102), 80.4%(82/102), 73.5%(75/102), which were higher than the control group 84.0%(84/100), 46.0%(46/100), 52.0%(52/100), 17.0%(17/100). The differences were statistically significant ( χ2 values were 4.18-65.06, all P<0.05). Conclusions:The rehabilitation bridging mode could connect the functional exercise needs of patients at different stages of rehabilitation, provide personalized, continuous, and standardized functional exercise guidance for patients, help them improve the effect of functional exercise, and improve their self management ability.
6.On the making and application of animations for medical teaching
Chunshen LI ; Qing CAI ; Junzhen TAN ; Tao ZHOU ; Chunjing SONG ; Pengjuan XU ; Jingbo LIU
Chinese Journal of Medical Education Research 2019;18(7):687-691
This study explores the application of animation in medical teaching. On the one hand, the status quo of the application of animation in medical teaching was analyzed by conducting questionnaire survey for the effect of animation-enhanced teaching of the biology course; on the other hand, new animations were made by the researchers to analyze its effect on the students' self-study. The results showed that the scores of the students receiving text and teaching animation resources were significantly higher than that of students receiving only textual information in the learning process (P<0.01), and the same goes for the number of the students that complete the >75% of the learning content. The results showed that the teaching animation can improve the students' self-study performance and raise their interest in self-study.