Objective To explore the influential factors of dangerous placenta previa pathogenesis,and to analyze their peri natal period outcomes.Methods The clinical data in 143 pregnant women and parturients of dangerous placenta previa(research group) and 286 pregnant women and parturients of non-dangerous placenta previa(control group) in our hospital from January 2011 to December 2015 were retrospectively analyzed.Results The average age of the research group was higher than that of the control group (t =2.92,P =0.004);the previous pregnancy frequency,previous parity,previous abortion frequency,previous cesarean delivery frequency and incidence of placenta previa in the research group were higher than those in the control group(P＜0.01);the incidence of placenta previa in the research group was higher than that in the control group(x2 =7.60,P=0.006);the prenatal gestational weeks of the research group were lower than those of the control group(t=-12.33,P＜0.01).The multi-factor analysis showed that the age,previous abortion frequency and previous cesarean delivery frequency were the influence factors of placenta previa occurrence.Among them,the previous cesarean delivery frequency was the main risk factor.The occurrence rates of antepartum hemorrhage,postpartum hemorrhage,uterine removal and premature infants in the research group were higher than those in the control group(P＜0.01);The intraoperative blood loss of the research group was higher than that of the control group(P＜0.05);the neonatal birth weight and the 1 min Apgar score of the research group were lower than those in the control group(P＜0.05).Conclusion The age,previous abortion frequency and previous cesarean section frequency are related to the occurrence of dangerous placenta previa.

Objective To investigate the effect of comprehensive treatment in the treatment of knee osteoar-thritis by taking orally and external Chinese medicine with ozone injected the joint cavity.Methods 834 patients with knee osteoarthritis(1 212 knee joints)were randomly selected,after two courses of the comprehensive treatment,with excellent,good,fair and bad four levels to evaluate the therapeutic effect.Results After two courses of comprehensive treatment,534 cases were excellent,461 cases were good,181 cases were fair,36 cases were bad,the fine rate was 82.1%.Conclusion The comprehensive treatment is an effective method in knee osteoarthritis by taking orally and external Chinese medicine with ozone injected the joint cavity.

Objective: To explore the peri-operative application of GLP-1 analogue and insulin on myocardial perfusion and clinical prognosis in patients of acute ST segment elevation myocardial infarction (STEMI) with stress-induced hyperglycemia. Methods: Our research was a prospective single center randomized control study. A total of 114 consecutive STEMI patients received percutaneous coronary intervention (PCI) within 12h of onset were enrolled, the patients had no diabetes while blood glucose ≥11.1mmol/L at immediate admission. Based on random number table, the patients were divided into 2 groups: Observation group, the patients received GLP-1 analogue, n=59 and Control group, the patients received insulin, n=55. The post-operative myocardial perfusion, indicators of myocardial damage and cardiac function, myocardial infarct area (MIA) and myocardial salvage index (MSI) were compared between 2 groups. The patients were followed-up for 6 months to record the incidence of major adverse cardiovascular events (MACE). Results: At peri-operative period, compared with Control group, Observation group had decreased peak values of creatine kinase isoenzyme (CK-MB) and troponin T (cTnT), P<0.05. At 6 months post-operation, compared with Control group, Observation group showed increased myocardial perfusion and left ventricular ejection fraction (LVEF), P<0.05, reduced MIA (15±12) g vs (20±14) g, P<0.05 and 12% elevated MSI as (0.64±0.13) vs (0.56±0.12), P<0.001. The MACE incidence was similar between 2 groups, P=0.217. Conclusion: In STEMI patients with stress-induced hyperglycemia, peri-operative application of GLP-1 analogue may safely regulate blood glucose, improve cardiac perfusion and function, reduce MIA; while it had no influence on myocardial perfusion at peri-operative period and no impact on MACE occurrence at 6 months post-operation.

Objective To investigate the relationship between serum PCT,CRP,BNP and cardiac troponin I (cTnI)and its clinical significance in patients with sepsis.Methods 112 patients with sepsis treated in our hospital were collected.Patients were divided into sepsis,severe sepsis and septic shock groups according to their degree of illness.The serum levels of cTnI and cTnI were measured in peripheral blood samples of pa-tients with sepsis,severe sepsis and sepsis shock.To analyze the correlation between serum cTnI and cTn I in patients with sepsis.The levels of BNP and cTnI were significantly higher in septic shock group than in severe sepsis group.The difference was statistically significant(P<0.01),and that in severe sepsis group was signif-icantly higher than that in sepsis group(P<0.01).The results of correlation analysis showed that there was a positive correlation between serum PCT,BNP,CRP and cTnI levels,but the correlation was PCT(r =0.831)>BNP(r=0.456)>CRP(r=0.287).Results Conclusion cTnI and serum PCT,CRP,BNP are in the serum of the patients.With the exacerbation of sepsis patients,there will be more significant myocardial injury symptoms.

Objective To explore key points of nursing in treatment of tibial bone defect by united Ilizarov technology and bone transport. Methods A total of 12 patients treated tibial bone defect with combined Ilizarov technology and bone transport were retrospectively analyzed and summarized. Results All 12 patients were followed up for 5 to 24 months. Their average bone healing time was (9. 4 ± 2. 6) months, and average external fixation removal time was (10. 6 ± 2. 6) months. In one case, a little infection happened to the nail trail; after removal of crusts, the local part was cleaned with 75% alcohol cotton swab and kept dry, then the infection became better 2 days later. In another case, nonunion happened between the bone transport segment and the distal segment, so bone graft was done again. 2 cases of limb pain became better after delaying bone transport. No patients had complications due to nursing care. Conclusions Application of Ilizarov technique combined with bone transport on the treatment of tibial bone defect has advantages like small trauma, quick bone healing, equal length of lower limbs, and flexible knee joints. To guarantee operation effect and to improve patients′satisfaction, what is needed is postoperative observation and nursing of complications, psychological nursing, nursing in bone transport period, functional exercise and discharge guidance.

Objective To explore the effects of homogeneity management on the nursing quality in regional medical consortium. Methods A new nursing command system was established in the regional medical consortium. During October 2014 to October 2016, 45 union hospitals affiliated to Zhengzhou Central Hospital had carried out diversified training, unified culture construction and other measures to achieve homogeneity management, appling PDCA cycle management model all through. Ten nurses and ten patients were randomly selected from each department to conduct the regional medical consortium care status survey and patient satisfaction survey respectively. After two years intervention, the difference of nursing quality and patient satisfaction in the affiliated hospitals of the regional medical consortium were analyzed and compared. Results Compared with those who did not have homogeneity management, the qualified rate of first aid, the pass rate of ward management and patient satisfaction were significantly improved in the affiliated hospitals of the regional medical consortium, and the differences were statistically significant (P< 0.01). Conclusions Nursing homogeneity management can effectively improve the quality of nursing care in the affiliated hospitals of the regional medical consortium, ensure the safety of care and improve patient satisfaction.

Objective To observe the effect of quality nursing intervention on the compliance and pulmonary function of children with asthma.Methods A total of 50 patients with asthma were enrolled in our hospital and were randomly divided into observation group(n=25) and control group (n=25).All the children were treated with the same type of atomization, the control group implemented the traditional way of care, and the observation group additionally given quality care intervention.Asthma symptoms disappeared time, oxygen saturation, lung function [The first second forced expiratory volume (FEV1), forced vital capacity (FVC), peak expiratory flow rate (PEFR)], and medication compliance were observed.Results The symptoms of cough and asthma in the observation group were significantly shorter, and the oxygen saturation was higher than that of the control group (P<0.05).There was no significant difference in FEV1, FVC and PEFR between the two groups before and after nursing intervention (P>0.05).The levels of FEV1, FVC and PEFR in the two groups were significantly improved after treatment intervention, and the improvement of lung function in the observation group was better than that in the control group (P <0.05).The overall adherence rate of the observation group was higher than that of the control group, the difference was statistically significant (P<0.05).Conclusion The implementation of high-quality care intervention in children with asthma aerosol can significantly alleviate asthma, cough symptoms, shorten the treatment and hospital stay, improve children''s treatment compliance, improve lung function levels, the application effect is remarkable, so it is worth further application and promotion.

Objective To observe the effect of quality nursing intervention on the compliance and pulmonary function of children with asthma.Methods A total of 50 patients with asthma were enrolled in our hospital and were randomly divided into observation group(n=25) and control group (n=25).All the children were treated with the same type of atomization, the control group implemented the traditional way of care, and the observation group additionally given quality care intervention.Asthma symptoms disappeared time, oxygen saturation, lung function [The first second forced expiratory volume (FEV1), forced vital capacity (FVC), peak expiratory flow rate (PEFR)], and medication compliance were observed.Results The symptoms of cough and asthma in the observation group were significantly shorter, and the oxygen saturation was higher than that of the control group (P<0.05).There was no significant difference in FEV1, FVC and PEFR between the two groups before and after nursing intervention (P>0.05).The levels of FEV1, FVC and PEFR in the two groups were significantly improved after treatment intervention, and the improvement of lung function in the observation group was better than that in the control group (P <0.05).The overall adherence rate of the observation group was higher than that of the control group, the difference was statistically significant (P<0.05).Conclusion The implementation of high-quality care intervention in children with asthma aerosol can significantly alleviate asthma, cough symptoms, shorten the treatment and hospital stay, improve children''s treatment compliance, improve lung function levels, the application effect is remarkable, so it is worth further application and promotion.

Objective To assess the efficiency and safety of the bronchoscopic CO2cryotherapy to remove bronchial foreign body in children. Methods From Oct 2012 to Dec 2016, 8 cases diagnosed with the presence of bronchial foreign body were undergone the treatment with the bronchoscopic CO2cryotherapy. The clinical data about the efficiency and complication were collected and retrospectively analyzed. Results In the 8 cases, we successfully removed the bronchial foreign bodies without complications. In 2 cases, the foreign bodies were removed successfully, but cryotherapy partially damaged the airway mucosa, causing topical airway obstruction because of the newly developed granulation tissue. No serious adverse reactions or complications were observed after the treatment. Conclusions Removal of bronchial foreign bodies using bronchoscopic CO2 cryotherapy is an easy and effective method which can be used as a supplementary procedure for the bronchoscopic removal of foreign bodies in children's airways.

Objective To explore the value of low-dose multi-slice spiral computed tomography (MSCT) multi-stage scan and three-dimensional reconstruction in diagnosis of patients with gastric carcinoma.Methods A total of 40 patients with gastric carcinoma were selected.All the patients were conducted with low-dose MSCT scan,dynamic contrast scanning and three-dimensional reconstruction scan,and then were processed by multi-planar reconstruction,volume reconstruction and CT virtual endoscopy.Primary lesions in gastric cancer,peripheral infiltration and distant metastasis were observed.Results All the patients were satisfied with the low dose MSCT images,and all of them found primary gastric lesions and had satisfactory diagnosis rates of gastric peripheral infiltration,lymph node metastasis and distant metastasis.Conclusion Low-dose MSCT multi-stage scan and three-dimensional reconstruction can reduce the radiation dose and reveal the primary gastric lesions,gastric peripheral infiltration and distant metastasis.