1.Lymph Node Stations of Pancreas Which Are Identified in Real Color Sectioned Images of a Cadaver With Pancreatic Cancer
Chung Yoh KIM ; Yongwook JUNG ; Jin Seo PARK
Journal of Korean Medical Science 2023;38(46):e392-
Background:
In pancreatic cancer surgery, anatomical understanding of lymph node metastases is required. Distinguishing lymph nodes in computed tomography or magnetic resonance imaging is challenging for novice doctors and medical students because of their small size and similar color to surrounding tissues. This study aimed to enhance our understanding of the clinical anatomy of lymph node stations relevant to pancreatic cancer using newly sectioned images of a cadaver with true color and high resolution and their three-dimensional (3D) models.
Methods:
An 88-year-old female cadaver who died of pancreatic cancer was serially sectioned.Among the sectioned images of the whole body (0.05 mm-sized pixel, 48 bits color), images of the abdomen were selected, and examined to identify lymph nodes and nearby structures.34 structures (9 in digestive system; 1 in urinary system; 2 in cardiovascular system; 22 in lymphatic system) were segmented on the sectioned images. Based on the sectioned and segmented images, volume and surface models were produced.
Results:
Among the known 28 lymph node stations, 21 stations were identified through location, size, and color of normal and abnormal structures in the sectioned images and 3D models. Two near the splenic artery could not be separated from the cancer tissue, and the remaining five were not clearly identified. In the surface models, the shape and location of lymph node stations could be confirmed with nearby structures.
Conclusion
The lymph node stations relevant to pancreatic cancer can be anatomically understood by using the sectioned images and 3D models which contain true color and high resolution.
2.Identification of cranial nerve ganglia using sectioned images and three-dimensional models of a cadaver
Chung Yoh KIM ; Jin Seo PARK ; Beom Sun CHUNG
The Korean Journal of Pain 2022;35(3):250-260
Background:
Cranial nerve ganglia, which are prone to viral infections and tumors, are located deep in the head, so their detailed anatomy is difficult to understand using conventional cadaver dissection. For locating the small ganglia in medical images, their sectional anatomy should be learned by medical students and doctors.The purpose of this study is to elucidate cranial ganglia anatomy using sectioned images and three-dimensional (3D) models of a cadaver.
Methods:
One thousand two hundred and forty-six sectioned images of a male cadaver were examined to identify the cranial nerve ganglia. Using the real color sectioned images, real color volume model having a voxel size of 0.4 × 0.4 × 0.4 mm was produced.
Results:
The sectioned images and 3D models can be downloaded for free from a webpage, anatomy.dongguk.ac.kr/ganglia. On the images and model, all the cranial nerve ganglia and their whole course were identified. In case of the facial nerve, the geniculate, pterygopalatine, and submandibular ganglia were clearly identified.In case of the glossopharyngeal nerve, the superior, inferior, and otic ganglia were found. Thanks to the high resolution and real color of the sectioned images and volume models, detailed observation of the ganglia was possible. Since the volume models can be cut both in orthogonal planes and oblique planes, advanced sectional anatomy of the ganglia can be explained concretely.
Conclusions
The sectioned images and 3D models will be helpful resources for understanding cranial nerve ganglia anatomy, for performing related surgical procedures.
3.Dawn of the Visible Monkey: Segmentation of the Rhesus Monkey for 2D and 3D Applications
Chung Yoh KIM ; Ae-Kyoung LEE ; Hyung-Do CHOI ; Jin Seo PARK
Journal of Korean Medical Science 2020;35(15):e100-
Background:
To properly utilize the sectioned images in a Visible Monkey dataset, it is essential to segment the images into distinct structures. This segmentation allows the sectioned images to be compiled into two-dimensional or three-dimensional software packages to facilitate anatomy and radiology education, and allows them to be used in experiments involving electromagnetic radiation. The purpose of the present study was to demonstrate the potential of the sectioned images using the segmented images.
Methods:
Using sectioned images of a monkey's entire body, 167 structures were segmented using Adobe Photoshop. The segmented images and sectioned images were packaged into the browsing software. Surface models were made from the segmented images using Mimics. Volume models were made from the sectioned images and segmented images using MRIcroGL.
Results:
In total, 839 segmented images of 167 structures in the entire body of a monkey were produced at 0.5-mm intervals (pixel size, 0.024 mm; resolution, 8,688 × 5,792; color depth, 24-bit color; BMP format). Using the browsing software, the sectioned images and segmented images were able to be observed continuously and magnified along with the names of the structures. The surface models of PDF file were able to be handled freely using Adobe Reader. In the surface models, the space information of all segmented structures was able to be identified using Sim4Life. On MRIcroGL, the volume model was able to be browsed and sectioned at any angle with real color.
Conclusion
Browsing software, surface models, and volume models are able to be produced based on the segmentation of the sectioned images. These will be helpful for students and researchers studying monkey anatomy and radiology, as well as for biophysicists examining the effects of electromagnetic radiation.
4.A review of the ethmoidal foramina and their clinical application
Athena COHEN ; Chung Yoh KIM ; Kazzara RAEBURN ; Kathleen BUBB ; Yoko TABIRA ; Joe IWANAGA ; R. Shane TUBBS
Anatomy & Cell Biology 2025;58(1):1-7
The ethmoidal foramina (EF), located on the medial orbital wall along the frontoethmoidal sutures, are critical anatomical landmarks for surgeries involving the medial orbital wall. This review aimed to review the surgical anatomy of the EF, including their embryology and radiology. Although the frontoethmoidal sutures mostly have two foramina passing through them, there are reports of single foramen or multiple, up to six foramina. These foramina provide a passage for the ethmoidal arteries and nerves, branches of ophthalmic arteries and nerves. The surgical guideline “24-12-6” is based on the approximate distance between the anterior lacrimal crest, the anterior and posterior ethmoidal arteries, and the optic canal, commonly used to navigate this area. However, some studies from various populations defined different ratios.Embryologically, the EF were formed by the union of intramembranous ossified frontal bones and endochondral ossified ethmoid bones. EF and neurovascular structures can be identified in computed tomography even in the 3 mm sectional intervals. A comprehensive anatomical understanding of EF will help clinicians improve surgical guidelines and ultimately reduce the risk of complications.
5.A review of the ethmoidal foramina and their clinical application
Athena COHEN ; Chung Yoh KIM ; Kazzara RAEBURN ; Kathleen BUBB ; Yoko TABIRA ; Joe IWANAGA ; R. Shane TUBBS
Anatomy & Cell Biology 2025;58(1):1-7
The ethmoidal foramina (EF), located on the medial orbital wall along the frontoethmoidal sutures, are critical anatomical landmarks for surgeries involving the medial orbital wall. This review aimed to review the surgical anatomy of the EF, including their embryology and radiology. Although the frontoethmoidal sutures mostly have two foramina passing through them, there are reports of single foramen or multiple, up to six foramina. These foramina provide a passage for the ethmoidal arteries and nerves, branches of ophthalmic arteries and nerves. The surgical guideline “24-12-6” is based on the approximate distance between the anterior lacrimal crest, the anterior and posterior ethmoidal arteries, and the optic canal, commonly used to navigate this area. However, some studies from various populations defined different ratios.Embryologically, the EF were formed by the union of intramembranous ossified frontal bones and endochondral ossified ethmoid bones. EF and neurovascular structures can be identified in computed tomography even in the 3 mm sectional intervals. A comprehensive anatomical understanding of EF will help clinicians improve surgical guidelines and ultimately reduce the risk of complications.
6.A review of the ethmoidal foramina and their clinical application
Athena COHEN ; Chung Yoh KIM ; Kazzara RAEBURN ; Kathleen BUBB ; Yoko TABIRA ; Joe IWANAGA ; R. Shane TUBBS
Anatomy & Cell Biology 2025;58(1):1-7
The ethmoidal foramina (EF), located on the medial orbital wall along the frontoethmoidal sutures, are critical anatomical landmarks for surgeries involving the medial orbital wall. This review aimed to review the surgical anatomy of the EF, including their embryology and radiology. Although the frontoethmoidal sutures mostly have two foramina passing through them, there are reports of single foramen or multiple, up to six foramina. These foramina provide a passage for the ethmoidal arteries and nerves, branches of ophthalmic arteries and nerves. The surgical guideline “24-12-6” is based on the approximate distance between the anterior lacrimal crest, the anterior and posterior ethmoidal arteries, and the optic canal, commonly used to navigate this area. However, some studies from various populations defined different ratios.Embryologically, the EF were formed by the union of intramembranous ossified frontal bones and endochondral ossified ethmoid bones. EF and neurovascular structures can be identified in computed tomography even in the 3 mm sectional intervals. A comprehensive anatomical understanding of EF will help clinicians improve surgical guidelines and ultimately reduce the risk of complications.
7.A review of the ethmoidal foramina and their clinical application
Athena COHEN ; Chung Yoh KIM ; Kazzara RAEBURN ; Kathleen BUBB ; Yoko TABIRA ; Joe IWANAGA ; R. Shane TUBBS
Anatomy & Cell Biology 2025;58(1):1-7
The ethmoidal foramina (EF), located on the medial orbital wall along the frontoethmoidal sutures, are critical anatomical landmarks for surgeries involving the medial orbital wall. This review aimed to review the surgical anatomy of the EF, including their embryology and radiology. Although the frontoethmoidal sutures mostly have two foramina passing through them, there are reports of single foramen or multiple, up to six foramina. These foramina provide a passage for the ethmoidal arteries and nerves, branches of ophthalmic arteries and nerves. The surgical guideline “24-12-6” is based on the approximate distance between the anterior lacrimal crest, the anterior and posterior ethmoidal arteries, and the optic canal, commonly used to navigate this area. However, some studies from various populations defined different ratios.Embryologically, the EF were formed by the union of intramembranous ossified frontal bones and endochondral ossified ethmoid bones. EF and neurovascular structures can be identified in computed tomography even in the 3 mm sectional intervals. A comprehensive anatomical understanding of EF will help clinicians improve surgical guidelines and ultimately reduce the risk of complications.
8.A review of the ethmoidal foramina and their clinical application
Athena COHEN ; Chung Yoh KIM ; Kazzara RAEBURN ; Kathleen BUBB ; Yoko TABIRA ; Joe IWANAGA ; R. Shane TUBBS
Anatomy & Cell Biology 2025;58(1):1-7
The ethmoidal foramina (EF), located on the medial orbital wall along the frontoethmoidal sutures, are critical anatomical landmarks for surgeries involving the medial orbital wall. This review aimed to review the surgical anatomy of the EF, including their embryology and radiology. Although the frontoethmoidal sutures mostly have two foramina passing through them, there are reports of single foramen or multiple, up to six foramina. These foramina provide a passage for the ethmoidal arteries and nerves, branches of ophthalmic arteries and nerves. The surgical guideline “24-12-6” is based on the approximate distance between the anterior lacrimal crest, the anterior and posterior ethmoidal arteries, and the optic canal, commonly used to navigate this area. However, some studies from various populations defined different ratios.Embryologically, the EF were formed by the union of intramembranous ossified frontal bones and endochondral ossified ethmoid bones. EF and neurovascular structures can be identified in computed tomography even in the 3 mm sectional intervals. A comprehensive anatomical understanding of EF will help clinicians improve surgical guidelines and ultimately reduce the risk of complications.
9.A comprehensive review of the mental spine
Ross CHAMPAGNE ; Rithvik VUTUKURI ; Chung Yoh KIM ; R. Shane TUBBS ; Joe IWANAGA
Anatomy & Cell Biology 2024;57(1):1-6
Clinical case reports and research regarding the mental spines and their associated structures create a detailed picture of the floor of the mouth for assessment during clinical treatment. This compilation of information covers the mental spines, the attached geniohyoid and genioglossus muscles, the lingual foramina, and the veins and arteries of the jaw and floor of the mouth. It is important to consider the variations in the mental spines for oral and maxillofacial treatment involving the mandible. Differences in anatomy of the mental spine, including their number, location, and size, can impact diagnosis and treatment approaches.
10.CT Diagnosis of Intestinal Obstruction: Findings and Usefulness.
Mi Young KIM ; Chan Sup PARK ; Kyung Rae KIM ; Yong Woon SHIN ; Sung Tae OH ; Chang Hae SUH ; Won Kyun CHUNG ; Soon Gu CHO ; Won Jae CHUNG ; Kyu Tong YOH ; Cheol Su OK
Journal of the Korean Radiological Society 1994;30(5):875-880
PURPOSE: To present the findings of intestinal obstruction and evaluate the value of CT in the diagnosis of intestinal obstruction. MATERIALS AND METHODS: We prospectively analyzed CT scans of twenty-two patients who were suspected to have intestinal obstruction. All 22 patients were confirmed with surgery:10 patients with adhesion, four with primary intestinal tumor, one with metastatic intestinal tumor, two with inflammatory bowel disease, two with intussusception, two with extrinsic compression by ovarian tumor, and one with inguinal hernia. The CT scans were evaluated with special attention to their causes, locations, and CT findings of intestinal obstruction. CT diagnosis and findings were compared with surgical results. RESULTS: Their causes were diagnosed correctly on CT scans in seventeen of 22 cases(77.3%). Locations of the intestinal obstruction were diagnosed correctly in 16 cases(72.7% ). The CT findings of intestinal obstruction were categorized into dilated proximal bowel loops with normal distal loops, thickening of the affected bowel wall, presence of the transitional zone, and no detectable abnormalities. The associated extraluminal findings were fat infiltration around the dilated bowel loops, ascites, and mesenteric lymphnodes enlargement. There were two limitations of CT in our study:first, no detectable differences between jejunum and ileum on CT scans, and second, difficulty in differential diagnosis between thickened bowel wall mimicking normal non-dilated segment and mechanical obstruction from tumors or inflammatory bowel diseases. CONCLUSION: We conclude that CT is useful method in the evaluation of causes and locations of intestinal obstruction and the demonstration of the associated extraluminal abnormalities.
Ascites
;
Diagnosis*
;
Diagnosis, Differential
;
Hernia, Inguinal
;
Humans
;
Ileum
;
Inflammatory Bowel Diseases
;
Intestinal Obstruction*
;
Intussusception
;
Jejunum
;
Prospective Studies
;
Tomography, X-Ray Computed