1.Lymph Node Stations of Pancreas Which Are Identified in Real Color Sectioned Images of a Cadaver With Pancreatic Cancer
Chung Yoh KIM ; Yongwook JUNG ; Jin Seo PARK
Journal of Korean Medical Science 2023;38(46):e392-
Background:
In pancreatic cancer surgery, anatomical understanding of lymph node metastases is required. Distinguishing lymph nodes in computed tomography or magnetic resonance imaging is challenging for novice doctors and medical students because of their small size and similar color to surrounding tissues. This study aimed to enhance our understanding of the clinical anatomy of lymph node stations relevant to pancreatic cancer using newly sectioned images of a cadaver with true color and high resolution and their three-dimensional (3D) models.
Methods:
An 88-year-old female cadaver who died of pancreatic cancer was serially sectioned.Among the sectioned images of the whole body (0.05 mm-sized pixel, 48 bits color), images of the abdomen were selected, and examined to identify lymph nodes and nearby structures.34 structures (9 in digestive system; 1 in urinary system; 2 in cardiovascular system; 22 in lymphatic system) were segmented on the sectioned images. Based on the sectioned and segmented images, volume and surface models were produced.
Results:
Among the known 28 lymph node stations, 21 stations were identified through location, size, and color of normal and abnormal structures in the sectioned images and 3D models. Two near the splenic artery could not be separated from the cancer tissue, and the remaining five were not clearly identified. In the surface models, the shape and location of lymph node stations could be confirmed with nearby structures.
Conclusion
The lymph node stations relevant to pancreatic cancer can be anatomically understood by using the sectioned images and 3D models which contain true color and high resolution.
2.Identification of cranial nerve ganglia using sectioned images and three-dimensional models of a cadaver
Chung Yoh KIM ; Jin Seo PARK ; Beom Sun CHUNG
The Korean Journal of Pain 2022;35(3):250-260
Background:
Cranial nerve ganglia, which are prone to viral infections and tumors, are located deep in the head, so their detailed anatomy is difficult to understand using conventional cadaver dissection. For locating the small ganglia in medical images, their sectional anatomy should be learned by medical students and doctors.The purpose of this study is to elucidate cranial ganglia anatomy using sectioned images and three-dimensional (3D) models of a cadaver.
Methods:
One thousand two hundred and forty-six sectioned images of a male cadaver were examined to identify the cranial nerve ganglia. Using the real color sectioned images, real color volume model having a voxel size of 0.4 × 0.4 × 0.4 mm was produced.
Results:
The sectioned images and 3D models can be downloaded for free from a webpage, anatomy.dongguk.ac.kr/ganglia. On the images and model, all the cranial nerve ganglia and their whole course were identified. In case of the facial nerve, the geniculate, pterygopalatine, and submandibular ganglia were clearly identified.In case of the glossopharyngeal nerve, the superior, inferior, and otic ganglia were found. Thanks to the high resolution and real color of the sectioned images and volume models, detailed observation of the ganglia was possible. Since the volume models can be cut both in orthogonal planes and oblique planes, advanced sectional anatomy of the ganglia can be explained concretely.
Conclusions
The sectioned images and 3D models will be helpful resources for understanding cranial nerve ganglia anatomy, for performing related surgical procedures.
3.Dawn of the Visible Monkey: Segmentation of the Rhesus Monkey for 2D and 3D Applications
Chung Yoh KIM ; Ae-Kyoung LEE ; Hyung-Do CHOI ; Jin Seo PARK
Journal of Korean Medical Science 2020;35(15):e100-
Background:
To properly utilize the sectioned images in a Visible Monkey dataset, it is essential to segment the images into distinct structures. This segmentation allows the sectioned images to be compiled into two-dimensional or three-dimensional software packages to facilitate anatomy and radiology education, and allows them to be used in experiments involving electromagnetic radiation. The purpose of the present study was to demonstrate the potential of the sectioned images using the segmented images.
Methods:
Using sectioned images of a monkey's entire body, 167 structures were segmented using Adobe Photoshop. The segmented images and sectioned images were packaged into the browsing software. Surface models were made from the segmented images using Mimics. Volume models were made from the sectioned images and segmented images using MRIcroGL.
Results:
In total, 839 segmented images of 167 structures in the entire body of a monkey were produced at 0.5-mm intervals (pixel size, 0.024 mm; resolution, 8,688 × 5,792; color depth, 24-bit color; BMP format). Using the browsing software, the sectioned images and segmented images were able to be observed continuously and magnified along with the names of the structures. The surface models of PDF file were able to be handled freely using Adobe Reader. In the surface models, the space information of all segmented structures was able to be identified using Sim4Life. On MRIcroGL, the volume model was able to be browsed and sectioned at any angle with real color.
Conclusion
Browsing software, surface models, and volume models are able to be produced based on the segmentation of the sectioned images. These will be helpful for students and researchers studying monkey anatomy and radiology, as well as for biophysicists examining the effects of electromagnetic radiation.
4.A comprehensive review of the mental spine
Ross CHAMPAGNE ; Rithvik VUTUKURI ; Chung Yoh KIM ; R. Shane TUBBS ; Joe IWANAGA
Anatomy & Cell Biology 2024;57(1):1-6
Clinical case reports and research regarding the mental spines and their associated structures create a detailed picture of the floor of the mouth for assessment during clinical treatment. This compilation of information covers the mental spines, the attached geniohyoid and genioglossus muscles, the lingual foramina, and the veins and arteries of the jaw and floor of the mouth. It is important to consider the variations in the mental spines for oral and maxillofacial treatment involving the mandible. Differences in anatomy of the mental spine, including their number, location, and size, can impact diagnosis and treatment approaches.
5.A comprehensive review of the mental spine
Ross CHAMPAGNE ; Rithvik VUTUKURI ; Chung Yoh KIM ; R. Shane TUBBS ; Joe IWANAGA
Anatomy & Cell Biology 2024;57(1):1-6
Clinical case reports and research regarding the mental spines and their associated structures create a detailed picture of the floor of the mouth for assessment during clinical treatment. This compilation of information covers the mental spines, the attached geniohyoid and genioglossus muscles, the lingual foramina, and the veins and arteries of the jaw and floor of the mouth. It is important to consider the variations in the mental spines for oral and maxillofacial treatment involving the mandible. Differences in anatomy of the mental spine, including their number, location, and size, can impact diagnosis and treatment approaches.
6.A comprehensive review of the mental spine
Ross CHAMPAGNE ; Rithvik VUTUKURI ; Chung Yoh KIM ; R. Shane TUBBS ; Joe IWANAGA
Anatomy & Cell Biology 2024;57(1):1-6
Clinical case reports and research regarding the mental spines and their associated structures create a detailed picture of the floor of the mouth for assessment during clinical treatment. This compilation of information covers the mental spines, the attached geniohyoid and genioglossus muscles, the lingual foramina, and the veins and arteries of the jaw and floor of the mouth. It is important to consider the variations in the mental spines for oral and maxillofacial treatment involving the mandible. Differences in anatomy of the mental spine, including their number, location, and size, can impact diagnosis and treatment approaches.
7.CT Diagnosis of Intestinal Obstruction: Findings and Usefulness.
Mi Young KIM ; Chan Sup PARK ; Kyung Rae KIM ; Yong Woon SHIN ; Sung Tae OH ; Chang Hae SUH ; Won Kyun CHUNG ; Soon Gu CHO ; Won Jae CHUNG ; Kyu Tong YOH ; Cheol Su OK
Journal of the Korean Radiological Society 1994;30(5):875-880
PURPOSE: To present the findings of intestinal obstruction and evaluate the value of CT in the diagnosis of intestinal obstruction. MATERIALS AND METHODS: We prospectively analyzed CT scans of twenty-two patients who were suspected to have intestinal obstruction. All 22 patients were confirmed with surgery:10 patients with adhesion, four with primary intestinal tumor, one with metastatic intestinal tumor, two with inflammatory bowel disease, two with intussusception, two with extrinsic compression by ovarian tumor, and one with inguinal hernia. The CT scans were evaluated with special attention to their causes, locations, and CT findings of intestinal obstruction. CT diagnosis and findings were compared with surgical results. RESULTS: Their causes were diagnosed correctly on CT scans in seventeen of 22 cases(77.3%). Locations of the intestinal obstruction were diagnosed correctly in 16 cases(72.7% ). The CT findings of intestinal obstruction were categorized into dilated proximal bowel loops with normal distal loops, thickening of the affected bowel wall, presence of the transitional zone, and no detectable abnormalities. The associated extraluminal findings were fat infiltration around the dilated bowel loops, ascites, and mesenteric lymphnodes enlargement. There were two limitations of CT in our study:first, no detectable differences between jejunum and ileum on CT scans, and second, difficulty in differential diagnosis between thickened bowel wall mimicking normal non-dilated segment and mechanical obstruction from tumors or inflammatory bowel diseases. CONCLUSION: We conclude that CT is useful method in the evaluation of causes and locations of intestinal obstruction and the demonstration of the associated extraluminal abnormalities.
Ascites
;
Diagnosis*
;
Diagnosis, Differential
;
Hernia, Inguinal
;
Humans
;
Ileum
;
Inflammatory Bowel Diseases
;
Intestinal Obstruction*
;
Intussusception
;
Jejunum
;
Prospective Studies
;
Tomography, X-Ray Computed
8.Application of Ecklonia cava Kjellman by-product as a feed additive: enhancing weight gain, immunity and protection from Salmonella infection in chickens.
Soyeon PARK ; Chung Yoh KIM ; Bokyoung PARK ; Kiju KIM ; Keuntae PARK ; Jong Kwon HAN ; Tae Wook HAHN
Korean Journal of Veterinary Research 2016;56(4):255-260
The Ecklonia cava Kjellman by-product (ECBP) as a feed additive was evaluated in improvement of productivity and immune enhancement against Salmonella Gallinarum (SG). Lohmann Brown chickens proved SG-free were randomly divided into 3 groups of 8 chickens each. Chickens were fed with the experimental diet treatment: T0, Non treatment-commercial feed; T1, commercial feed with 0.5% ECBP; T2, commercial feed with 0.1% Lactobacillus plantarum. In this study, we evaluated the effect of T1 and T2 groups on the body weight and protective efficacy against SG in chickens. The results demonstrated that treatment of T1 group as a feed additive affected significantly body weight gaining in chickens. In addition, T1 group showed a significant different colonization of SG when compared to T2 and T0 groups. We also studied that serum IgG and interferon-γ levels were significantly different compared with other treatment groups. Therefore, we suggest that ECBP can be used as a good candidate of feed additives in chicken industry.
9.Hearing and Visual Loss with Renal Failure Due to Sodium Bromate Poisoning.
Jeong Jo JEONG ; Woo Chul CHUNG ; Yoon Hee CHOI ; Kyung Ah YOH ; Tak Yong KIM ; Kyung Su PARK ; Jong Min LEE ; Dong Chan JIN ; Yoon Sik CHANG ; Byung Kee BANG
Korean Journal of Nephrology 1997;16(4):824-827
Hair neutralizer in home permanent cold wave kits contains a 2% to 10% potassium or sodium bromate, which is colorless, odorless and tasteless solution. Bromate salts are extremely toxic oxidants. The reported toxic effects of bromates poisoning are vomiting, diarrhea, depression of central nervous system, oliguric acute renal failure, sensorineural hearing loss, peripheral neuropathy and hemolytic anemia. Deafness seems to be almost permanent. In many cases, the recovery of renal function is not complete and some of them are transformed to chronic renal failure and maintained on hemodialysis. Since the serious side effects of deafness and acute renal filure usually occur within 4-16 h after ingestion, prompt removal of the bromate from blood by peritoneal dialysis or hemodialysis, which are proven method of removal, should be performed immediately. Recently, we encountered a 37 year old female hairdresser who was admitted to St. Mary Hospital due to oligura, hearing loss and visual loss after ingestion of sodium bromate. The patient required regular hemodialysis therapy and no recovery of hearing and visual loss was evident up to 8 month follow up.
Acute Kidney Injury
;
Adult
;
Anemia, Hemolytic
;
Bromates
;
Central Nervous System
;
Deafness
;
Depression
;
Diarrhea
;
Eating
;
Female
;
Follow-Up Studies
;
Hair
;
Hearing Loss
;
Hearing Loss, Sensorineural
;
Hearing*
;
Humans
;
Kidney Failure, Chronic
;
Oxidants
;
Peripheral Nervous System Diseases
;
Peritoneal Dialysis
;
Poisoning*
;
Potassium
;
Renal Dialysis
;
Renal Insufficiency*
;
Salts
;
Sodium*
;
Vomiting