PURPOSE: To evaluate the anatomic and functional change in acutely obstructed kidneys, and the probability of functional recovery after resolving the obstruciton. MATERIALS AND METHODS: There were 5 animal groups(6 rabbits in each group)-normal control group, 4 acute ureteral obstruction group. Each of the latter group was imaged with Gd-DTPA enhanced dynamic MR 2, 6, 24, and 48 hours after ligation of the left proximal urter, respectively. We compared the findings of dynamic MR imaging and histopathological findings. RESULTS: We could observe centripetal movement of dark band pattern which could be defined as 3 phasesrenal cortex, outer medulla, and inner medulla in normal rabbits. The appearance of the dark band pattern was delayed or absent in ureteral obstruction group with a linear relationship to the duration of the obstruction. CONCLUSION: Gd-DTPA enhanced MR can be used to differentiate acute obstructive nephropathy from other causes of nephropathy and foretell the prognosis of the obstruction.
Animals ; Gadolinium DTPA* ; Kidney ; Ligation ; Magnetic Resonance Imaging* ; Prognosis ; Rabbits* ; Ureter* ; Ureteral Obstruction*

Authors attempted to examine the development of keratinocyte in the human fetal epiderrnis in term of the appearance of principal product of differentiation, the keratins. Immunohistochemical study (ABC method) using anti-prekeratin antibodies and anti-keratin antibodies was carried out on sampled skin from 9 human fetuses ranging in estirnated gestational age from 12 weeks to 27 weeks. As early as 12 weeks of embryonic life, the epidermis contained cytokeratin. At this stage of development, the embryonic epidermis consists of three-cell layer .' basal layer, intermediate layer, and periderm, all of them staining for prekeratin and keratin. A thick cornified layer developed at 24 weeks but was not stained for prekeratin and keratin. Hair germ of 12 week-fetus was recognized as bulges of basal cells that were stained for prekeratin and keratin. At 18 weeks of estimated gestational age, development has advanced to the bulbous hair peg stage at which point the primordia of nearly all the final structural components of follicles were established. In the final structureal cornponents of the follicles, outer root sheath and sebaceous gland were stained for prekeratin and keratin, whereas cortical and cuticular elements and inner root sheath were negative. There was no difference between immunostaining results for prekeratin and keratin except for the staining intensity. The appearance of these proteins early in development suggests their potential value in utero in the recognition of keratinization disorders.
Antibodies ; Epidermis* ; Fetus* ; Gestational Age ; Hair Follicle* ; Hair* ; Humans* ; Keratinocytes ; Keratins ; Sebaceous Glands ; Skin

No abstract available.
Agar* ; Diffusion* ; Phenol* ; Vibrio vulnificus* ; Vibrio*

The spine can be divided into two structural columns; an anterior column consisting of vertebral bodies, discs and ligaments and a posterior column consisting of the neural arch, facet joints and interconnecting ligaments. Disruption of both anterior and posterior columns results in spinal instability. Laminectomy may produce greater spinal instability and will convert a stable injury into a unstable one. The compression that exists in these injury is anterior and therefore posterior laminectomy do little more than produce spinal instability. The technique of open reduction and Harrington rod fixation of unstable fractures improved nursing care, shortened rehabilitation and was effective in maintaining fracture reduction and promoting bony healing. Between 1978 and 1980, thirteen consecutive patient with unstable fractures and fracture-dislocations of thoracolumbar spine were treated by open reduction and spinal fusion with Harrington rod fixation at the Department of Orthopaedic Surgery of the Han Gang and Kang Nam Sacred Heart Hospitals. The following results were obtained from analysis of the cases. 1. The reduction and stability after reduction with Hsrrington instrumentation was excellent. 2. Laminectomy produced greater spinal instability. 3. Early ambulation was possible and the period of hospitalization was shortened. 4. Neurological recovery from incomplete neural deficit was good but from complete paraplegia was less effective.
Dislocations ; Early Ambulation ; Heart ; Hospitalization ; Humans ; Laminectomy ; Ligaments ; Nursing Care ; Paraplegia ; Rehabilitation ; Spinal Fusion ; Spine ; Zygapophyseal Joint

We report a case of cerebriform intradermal nevus. a cause of cutis verticis gyrata that clinically they resembled neurofibroma and revealed histopathologic finding consistent with intradermal nevus. The patient was a 6 year-old boy, who had a 17x18cm, soft, convoluted. pigmented mass over the parietal and occipital regions. The lesion had been present since birth and had been slowly increasing in size with convolution.
Child ; Humans ; Male ; Neurofibroma ; Nevus, Intradermal* ; Parturition ; Rabeprazole

No abstract available.
Ischemia* ; Skin*

Ophthalmoplegic migraine is a syndrome characterized by the typical history of migrainous headache followed by ophthalmoplegia in the absence of demonstrable intracranial lesion. Until now, investigations of regional cerebral blood flow (CBF) in patient,; with migraine have been performed during prodromal and/or headache phases by brain SPECT with Tc-99m HMPAO. However, no such paper has described patients with ophthalmoplegic migraine. We present a 14-year-old girl with 4 episodes of paroxysmal migrainous headache on the right fronto-orbital area without aura followed by ptosis and diplopia, which were always gradually resolved without aberrant regeneration over 2 or 3 weeks period. Neurologic examination showed the right internal and external ophthalmoplegia. Diagnostic studies (including laboratory testis, Tensilon test, brain MRI, and cerebral angiography) were normal. Serial brain SPECT studies with Tc-99m HMPAO showed the presence of reversible ischemia in the branches of the posterior cerebral artery.
Adolescent ; Brain* ; Diplopia ; Edrophonium ; Epilepsy ; Female ; Headache ; Humans ; Ischemia* ; Magnetic Resonance Imaging ; Migraine Disorders ; Neurologic Examination ; Ophthalmoplegia ; Ophthalmoplegic Migraine* ; Posterior Cerebral Artery ; Regeneration ; Technetium Tc 99m Exametazime ; Testis ; Tomography, Emission-Computed, Single-Photon*

Malignant fibrous histiocytoma is the most common soft tissue sarcoma in adult life and shows a mixed proliferation of both fibroblsstic & histiocytic cells. We report a case of myxoid malignant fibrous histiocytoma involving right lower leg in a 68-year-old male patient, who presented with a childs palm-sized nodular mass of 3 years duration. Histoapthologically, the tumor had varying proportion of myxoid cellular components. The myxoid areas showed spindle and pleomorphic cells arranged in a vague storiform pattern, abrupt transition between a solidly cellular area and a myxoid area, and lipoblast-like cells. The cellular areas showed spindle cells arranged in a storiform pattern characteritic of the typical pleomorphic malignant fibrous histiocytorna.
Adult ; Aged ; Child ; Histiocytoma, Malignant Fibrous* ; Humans ; Leg ; Male ; Sarcoma

BACKGROUND: Since percutaneous mitral valvuloplasty(PMV) using balloon was introduced by Inoue in 1984, this procedure has been accepted as a new non-surgical therapeutic modality for the treatment of selected patients with mitral stenosis. Pregnant women with mitral stenosis has suffered from life threatening complication due to altered hemodynamic changes and heart failure. Surgical valvotomy has been performed after failure of medical therapy with high risk of fetal mortality and teratogenicity. PMV can be an adequate alternative to surgical valvotomy in pregnant women. METHODS: After precise echocardiographic examination of mitral valve and its surrounding structures including thrombi in left artrium was performed, antegrade transseptal procedure was done in all 3 cases with abdominal shield using Inoue balloon technique. RESULTS: Mitral valve area increased over 1.5cm2 and hemodynamic variables improved immediately after PMV. Symptoms subsided soon after PMV in all 3 cases. Healthy normal babies were delivered transvaginally without difficulties in all 3 patients. CONCLUSIONS: Percutaneous mitral valvuloplasty is a safe and effective therapeuteic alternative to surgical valvotomy in a pregnant women with mitral stenosis who failed medical therapy, in a high risk or symptomatic pregnant women.
Echocardiography ; Female ; Fetal Mortality ; Heart Failure ; Hemodynamics ; Humans ; Mitral Valve ; Mitral Valve Stenosis ; Pregnancy* ; Pregnant Women

No abstract available.
Dandy-Walker Syndrome*