1.The Successful Dissolution of 2 Cases of Fat Bezoars by Pancreatic Lipase.
Kyu Sik SHIM ; In Sik CHUNG ; Jin Min CHUNG ; Chang Don LEE ; Yong Suk LEE ; Hee Sik SUN ; Whan Kook CHUNG
Korean Journal of Gastrointestinal Endoscopy 1985;5(1):41-44
Gastric bezoars are large masses or concretions, composed with plant fiber, hair and miscellaneous foreign bodies, found in the stomach and occur usually as sequele of gastric surgery. We experienced 2 cases of fat bezoars which developed after drinking of melted beef fst. They had postprandial epigastric fullness and pain, those were relieved on supine and left recumbent position. Upper gastrointestinal series showed a large movable mass in the stomach in hoth cases. On gastrofibercopic examination, a large egg sized white bezoar was cordirmed in both cases and a gastrie ulcer at antrum associated in one case. In attempt to removal of the bezoars, we tried to break them, but failed because of its character. The patients were treated with pancreatic lipase containg digestives, Pancreon-F and Azintal. From one day after this treatment, symptoms were completely relieved. Five days later, we confirmed disappearance of bezoars by gastrofiberscopy. and upper gastrointestinal barium
Barium
;
Bezoars*
;
Drinking
;
Foreign Bodies
;
Hair
;
Humans
;
Lipase*
;
Ovum
;
Plants
;
Stomach
;
Ulcer
2.The Effect of Cimetidine in Treatment of Erosive Gastritis.
In Sik CHUNG ; Ho Sun LEE ; Chang Don LEE ; Kyu Won CHUNG ; Hee Sik SUN ; Whan Kook CHUNG
Korean Journal of Gastrointestinal Endoscopy 1985;5(1):17-22
In an attempt to evaluate the efficacy ef cimetidine in treatment of erosive gastritis, a praspective study wras done in 9 cases of heworrhagie gastritia, 4 cases yunctiform gastritis, 9 caees verrueous gastritia, and 9 caseis mixed type, Four hundred mg of cimetidine was given in the morning and at bedtime for 3 weeks. Evaluation ef the efficacy was assessed by clinical syinptoms acoring and by endoscopic findings of erosion before treatment, on the 8th day, on the 15th day, and on the 22th day of treatment in all patients. The results were as follows; 1) Clinical sytnptoms in patients with erosive gastritis were epigastric discamfortness(83. 9%), heart burn(80. 0%), indigestion(77, 6%), hunger pain(74.2%), belching(71.0%), anotexla (48.4%) and nausea(45.5%). There was no differenees of symptoms among the type of erosion. 2) Percent decrease in clinical eyxeptoms were; 45% on the 8th day, 68% on the 15th day, 81% on the 22th day of treatment. Ciinical symptoms in patients with punetiform gastritis lasted longer than other typea. 3) Disappearance of the gastric mucossl erosion was seen in 8 cases of hemorrhagic gastritis, 6 case of mixed type, 5 cases of verruceous gastritis, 2 cases of punctiform gastritis, and overall 21 Cases(67.7%) on the 22th day of treatment, endoscopieally. Faur eases af punctiform gastritis were transformed into verrueous gastritis during the treatment. 4) Disappearance of the erosion was observed more frequently in the mueosa of oxyntic area than that of antrum. This study suggests that cimetidine appears to be effective for relief of elinical symptoms in patients with erosive gastritis, and for treatment of hemorrhagic gastritis and erosions in the mucosa of oxyntic area,
Cimetidine*
;
Gastritis*
;
Heart
;
Humans
;
Hunger
;
Mucous Membrane
3.Solitary Bone Cyst of the Capitate: A Case Report
Yung Sik YANG ; Won Gap LEE ; Chung Surk LEE
The Journal of the Korean Orthopaedic Association 1980;15(2):366-369
Solitary bone cyst are usually found in the juxta-epiphyseal region of metaphysis of long bones of children. They are rarely seen in non-tubular bones. The following case describes what we believe to be a solitary cyst of the capitate. Cyst was treated by radical curettage and packing with autogenous iliac bone. The most recent evaluation 7 months after surgery showed no discomfort.
Bone Cysts
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Child
;
Curettage
;
Humans
4.Endoscopic Examination in Patients following Gastrectomy.
Yong Taek CHUN ; In Sik CHUNG ; Ahn Kie LEE ; Kyu Won CHUNG ; Hee Sik SUN ; Boo Sung KIM ; Whan Kook CHUNG
Korean Journal of Gastrointestinal Endoscopy 1984;4(1):13-19
It had heen emphasized the necessity for upper gastrointestinal endoscopic examinations in patients. Who has had gastrectomy and presents persisting gastrointestinal symptoms. This study was conducted to evaluate endoscopic findings and clinical symptoms in patients following gastrectomy. (continue...)
Gastrectomy*
;
Humans
5.Immunofluorescent monoclonal antibody(AE1/AE3) detection of bone marrow micrometastasis with primary breast cancer.
Jun Sik CHUNG ; Soo Jung LEE ; Kwing Bo KWON
Journal of the Korean Cancer Association 1993;25(6):912-919
No abstract available.
Bone Marrow*
;
Breast Neoplasms*
;
Breast*
;
Neoplasm Micrometastasis*
6.Relationship between plasma homocysteine levels and cardiovascular risk factors in healthy men.
Yangsoo JANG ; Eun Young CHO ; Jong Ho LEE ; Sik CHUNG
Korean Circulation Journal 1999;29(2):135-145
BACKGROUND: The high concentration of plasma total homocysteine is recently considered an independent risk factor for atherosclerosis. The purpose of this study was to provide reference ranges for plasma homocysteine levels and to investigate the relationship between plasma homocysteine and cardiovascular risk factors in healthy Korean men. METHODS: Anthropometric parameters, alcohol intake, cigarette use and nutrient intake were determined in 166 healthy men within a wide age range(30-69 yr). Serum levels of lipids, glucose and insulin levels during oral glucose tolerance test(OGTT), plasma amino acid concentrations and levels of antioxidant nutrients and enzymes were also measured. Hyperhomocysteinemia was defined as plasma homocysteine levels above the 90th percentile(> or =15micromol/L) of respective plasma homocysteine distribution in study subjects. Characteristics of hyperhomocysteinemic men(n=16) were compared to normohomocys- teinemic men(n=16) matched for age and body mass index. RESULTS: Plasma total homocysteine values ranged from 2.4 to 38.1micromol/L, a skewed, right-tailed distribution. The homocysteine levels of 25th, 50th and 75th percentile were 7.02, 9.61 and 12.4micromol/L, respectively. The mean concentration of plasma total homocysteine was 10.7micromol/L. Plasma total homocysteine level was positively correlated to body mass index, serum cholesterol and triglyceride levels and alcohol intake, but negatively correlated to serum bata-carotene concentration. In multivariate analysis, serum triglyceride level was the strongest determinant of plasma total homocysteine concentration. There were no significant differences between two groups in waist to hip ratio, alcohol intake, cigarette use, blood pressure and serum levels of glucose and insulin during OGTT. Hyperhomocysteinemic men had significantly higher mean values of serum triglyceride(258mg/dl), total cholesterol(226mg/dl), and LDL-cholesterol(140mg/dl) than normohomocysteinemic men. Hyperhomocysteinemic men showed a decrease in lipid corrected values of serum bata-carotene and alpha-tocopherol and plasma concentrations of serine and taurine, when compared to normohomocysteinemic men. The mean intakes of vitamin B6, folate, vitamin B12 and bata-carotene tended to decline by 25-30% in hyper- homocysteinemic group, when compared to normohomocysteinemic group. CONCLUSION: Our results indicate that healthy Korean men with hyperhomocys- teinemia show signs of hyperlipidemia and decreased antioxidants nutrients and these factors increase risk for coronary artery disease. In addition, hyperhomocysteinemia may affect amino acid metabolism related to homocysteine.
alpha-Tocopherol
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Antioxidants
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Atherosclerosis
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Blood Pressure
;
Body Mass Index
;
Cholesterol
;
Coronary Artery Disease
;
Folic Acid
;
Glucose
;
Glucose Tolerance Test
;
Homocysteine*
;
Humans
;
Hyperhomocysteinemia
;
Hyperlipidemias
;
Insulin
;
Male
;
Metabolism
;
Multivariate Analysis
;
Plasma*
;
Reference Values
;
Risk Factors*
;
Serine
;
Taurine
;
Tobacco Products
;
Triglycerides
;
Vitamin B 12
;
Vitamin B 6
;
Waist-Hip Ratio
7.A Statistical Study of Dermatoses During the Last 5 Years (1976~1980).
Dong Sik BANG ; Chung Koo CHO ; Sung Nack LEE
Korean Journal of Dermatology 1983;21(1):37-44
The incidence of skin diseases in the hospital practice cannot give a true picture of their prevalence in the population served. Nevertheless the hospital incidence figures usually offer the only available means of assessing prevalence, and therefore provide us with a potentially valuable source of information on the ecology of many skin disorders. (countinued..)
Ecology
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Incidence
;
Prevalence
;
Skin
;
Skin Diseases*
;
Statistics as Topic*
8.The efficacy of computed tomography in pretreatment evaluation of invasive cervical carcinoma.
In sik LEE ; Jae Hyun CHUNG ; Jung Eun MOK
Korean Journal of Obstetrics and Gynecology 1993;36(7):1808-1814
No abstract available.
9.Biochemical Analysis on Postmortem Specimens.
Nak Eun CHUNG ; Young Sik CHOI ; Han Young LEE
Korean Journal of Legal Medicine 2000;24(2):28-36
Because the postmortem changes rapidly distort values of many constituents in the body fluids, the determination of postmortem chemical changes and relation among body fluids is very important in medicolegal community. A laboratory result is not useful if appropriate data for comparison are lacking. The aim of this paper is to determine the reference ranges and the postmortem changes for chemical constituents in postmortem specimen. We examined 17 clinical laboratory parameters in cadaveric blood and vitreous humor obtained from 51 autopsy cases. The mean, standard error, standard deviation and confidence interval of all measured constituents were shown in Table 2 & Figure 1. The postmortem blood level of amylase, phosporus, LDH, ALT, AST and CPK are very higher than those of antemortem blood. The postmortem vitreous level of total bilirubin, triglyceride, GGT, alkaline phosphatase, albumin, total protein and cholesterol are very low and is not reliable. The ratio of vitreous/blood in calcium, BUN, creatine and uric acid are 0.74, 0.68, 0.29 and 0.23 in decreasing orders(Table 3,4). For the medical examiner or pathologist, routine chemical examinations of the vitreous humor can provide evidence of abnormality not apparent in gross or microscopic examination of the tissue. A more extensive study will be required, using a larger number of subjects, to establish the full range of variability.
Alkaline Phosphatase
;
Amylases
;
Autopsy
;
Bilirubin
;
Body Fluids
;
Cadaver
;
Calcium
;
Cholesterol
;
Confidence Intervals
;
Coroners and Medical Examiners
;
Creatine
;
Humans
;
Postmortem Changes
;
Reference Values
;
Triglycerides
;
Uric Acid
;
Vitreous Body
10.An experimental system on heart resistance by split dose hyperthermia
Myung Hee YOO ; Kyung Ja LEE ; Chung Sik RHEE
Journal of the Korean Radiological Society 1983;19(3):475-483
The study was undertaken to evaluate the heat resistance by split dose hyperthermia in various time intervaland temperature. For the experiments, 96 mice were divided into 2 groups: the first, 36 mice were used to evaluatethe skine reaction of mouse tail to single dose hyperathermia, the second, 60 mice were used to evaluate heatresistance by split dose hyperthermia in variuos time intervals. The results obtained are summarized as follows;1. The ND was 101 minutes at 43degrees centigrade(C) and 24 minutes at 45degrees C. 2. For a 1degrees C increasein temperature, a half in time was required to same degree of skin reaction. 3. Heat resistance was significantlydeveloped in split dose hyperthermia at 43degrees C and 45degrees C. 4. Development, maximum and decay of heatresistance were constant regardless of change in temperature. In summary, heat resistance in split dosehyperthermia is important in study and clinical application of heat therapy in malignant disease.
Animals
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Fever
;
Heart
;
Hot Temperature
;
Mice
;
Skin
;
Tail