No abstract available.
Humans ; Infant*

Congenital anomalies of the hand were reviewed, which were treated at Seoul National University Hospital from 1973 to 1982. The Conclusions are as follows. 1. Polydactyly is the most common congenital anomaly of the hand in this series. The next common congenital hand anomalies are trigger digit, syndactyly in that order. 2. Better results had been obtained with early reconstructive surgery within one year after birth. 3. Authors propose a new classification of polydactyly. In Joint type (type 1), the extradigit has its own epiphysis in its origin,and in Epiphyseal plate type (type 2) the extradigit do not have its own epiphyseal plate and seems to be derived from the physis of the more developed adjacent digit. We observed 22 cases of joint type and 10 cases of epiphyseal plate type. 4. 6 cases of macrodactyly had been observed. The complicated reconstructive surgery such as Tsuge and Barsky operation resulted in digital necrosis. So more simple and effective operation such as symphalangization would be attempted.
Classification ; Epiphyses ; Growth Plate ; Hand ; Joints ; Necrosis ; Parturition ; Polydactyly ; Seoul ; Syndactyly ; Trigger Finger Disorder

It had heen emphasized the necessity for upper gastrointestinal endoscopic examinations in patients. Who has had gastrectomy and presents persisting gastrointestinal symptoms. This study was conducted to evaluate endoscopic findings and clinical symptoms in patients following gastrectomy. (continue...)
Gastrectomy* ; Humans

No abstract available.
Bronchopulmonary Dysplasia* ; Humans ; Infant, Newborn

Craniofacial clefts are rare among facial anomalies with an incidence of 1.5 to 5 per 100,000 births, and 1 per 100 cases of cleft lip and palate. The Tessier No. 7 clefts are unusual lesions that result from failure of the embryonic mandibular and maxillary processes to properly fuse and form the corners of the mouth. We experienced a case of Tessier No. 7 craniofacial cleft in a 1 day-old female patient who presented with a macrostomia and auricular malformation. The diagnosis was established by clinical and radiographic findings. A brief review of literature was made.
Cleft Lip ; Diagnosis ; Female ; Humans ; Incidence ; Macrostomia ; Mouth ; Palate ; Parturition

The usual form of neurofibromatosis is characterized by cafe-au-Iait skin pigmentation and pedunculated fibrous skin tumors but in the severe form, malformations and tumors of the central nervous system may be associated with von Recklinghausen's disease. Schwannoma of the spinal sensory roots, of the vestibular part of 8th cranial nerve, and of the sensory root of the 5th cranial nerve are particularly common. Outside the central nervous system, other neuroectodermal tumors may develop including renal, pancreas, and suprarenal tumors. Recently, neurofibromatosis is subdivided into type 1 and 2, according to the site of involvement. Type 1 is classic von Recklinghausen's disease, and type 2 represents bilateral acoustic neurinomas. The authors experienced 2 cases neurofibromatosis type 1 and 1 case of neurofibromatosis type 2 in which neurofibromas involve both cerebello-pontine angles, multiple levels of spinal cord and cauda equina.
Cauda Equina ; Central Nervous System ; Cranial Nerves ; Neurilemmoma ; Neuroectodermal Tumors ; Neurofibroma ; Neurofibromatoses* ; Neurofibromatosis 1 ; Neurofibromatosis 2 ; Pancreas ; Skin ; Skin Pigmentation ; Spinal Cord

No abstract available.
Humans ; Infant, Newborn*

A patient had total occlusion of the left main coronary artery that was proved by coronary arteriography. Patients with total occlusion of the left main coronary artery have a varying clinical presentation and may have prolonged survival. In patients with good collaterals, left ventricular function may be preserved. This report reveiws the clinical and angiographic findings of a patient with occlusion of the left main coronary artery with symptoms of unstable angina pectoris but without congestive heart failure or EKG evidence of myocardial infarction.
Angina, Unstable ; Angiography ; Coronary Vessels* ; Electrocardiography ; Heart Failure ; Humans ; Myocardial Infarction ; Ventricular Function, Left

Death is not only a medical problem; it is also an ethical problem. When doctors face a dying neonate, their knowledge of bioethics and the opinions of ethical specialists and religious leaders are helpful for them and the family of the dying baby. In recent years, due to the increase of surviving babies who have suffered from severe illness, those born too small or too early, and those with severe anomalies in neonatal intensive care unit (NICU), we have met with complicated bioethical problems frequently. To lessen the burdens of doctors and the parents of the dying baby, I reviewed medical, ethical and religious articles about bioethics in adult death. My suggestions are listed as follows: 1) regular bioethical education and activation of bioethical committees in NICU, 2) a well-controlled nationwide database, 3) a hospice unit space and programs for dying baby in NICU, and 4) social support for pregnant women and financial support for the NICU.
Adult ; Bioethics ; Female ; Financial Support ; Hospices ; Humans ; Infant, Newborn ; Intensive Care, Neonatal ; Parents ; Pregnant Women ; Specialization

PURPOSE: We studied smooth muscle strips from rabbit gastric antrum and low esophageal sphincter (LES) to explore the difference between newborn and adult rabbit on erythromycin (EM)- induced contractions. Another aim of this study was to determine the mechanism of LES contractile activities induced by erythromycin (EM). METHODS: Muscle strips prepared from newborn and adult rabbits were stimulated with agonists such as KCl, motilin and EM, and the isometric tensions were measured. To study the underlying mechanism of EM-stimulated contraction of LES, the receptor antagonsts, including tetrodotoxin, hexamethonium, atropine, propranolol and phentholamine, were used. A high concentration of motilin (1 micrometer) was employed to provoke tachyphylaxis. RESULTS: Antral smooth muscle and LES from newborn rabbits developed less active force than those from adult rabbits when stimulated with KCl, motilin and erythromycin, however, the effective concentrations (EC50s) were similar in both age groups. Antral smooth muscle strips showed both tonic and phasic contractions but LES muscle strips showed only tonic contractions. These findings were observed in both newborn and adult rabbits. The contraction force of antral smooth muscle strips in response to agonists was greater than that of LES. The contractile response of LES to repeated motilin or EM administration was markedly decreased. EM- induced contractions of LES were markedly decreased by motilin tachyphylaxis but were unaffected by tetrodotoxin, hexamethonium, atropine or propranolol plus phentolamine. CONCLUSOIN: The data suggest that the contractilities of antrum and LES smooth muscle from newborn rabbit are less than those from adult ones, however, the effective concentratons of EM (EC50) are not different between the two age groups. The results also suggest that erythromycin induces the contraction of rabbit LES via motilin receptor in vitro.
Adult ; Atropine ; Erythromycin* ; Gastrointestinal Motility ; Hexamethonium ; Humans ; Infant, Newborn* ; Motilin ; Muscle, Smooth ; Phentolamine ; Propranolol ; Pyloric Antrum* ; Rabbits ; Tachyphylaxis ; Tetrodotoxin