Tuberous sclerosis is a complex neurocutaneous disease inherited as an autosomal dominant pattern, which is characterized by facial angio-fibroma, mental retardation and seizures. Many cases have been reported in the literatures, but familial cases are relatively rare. We present 9 cases of tuberous sclerois occuring througb 3 generations, which are 3 cases of angiofibroma, mental retardation and seizures, 2 cases of facial angiofibroma and seizures, 1 case of mental retardation and seizures and 3 cases who showed facial angiofibroma only. Two brothers in this family reveald icthyosis vulgaris without tuberous sclerosis.
Angiofibroma ; Family Characteristics* ; Humans ; Intellectual Disability ; Seizures ; Siblings ; Tuberous Sclerosis*

Trochanteric fractures frequently occur in the elderly patients and complications such as pneumonia, thromboembolic disease, decubitus ulcer, and urinary tract infection are common. The principle in the treatment of an elderly patient wlth trochanteric fractures have swung from traction to internal fixation due to such complications. Since the introduction of the Smith-Petersen nail, numerous internal fixation devices such as I-beam nail, Thornton plate, Jewett nail, and Holt nail have been developed. Recently compression hip screw is popular because of rigid internal fixation. Also many surgeons such as Evans, Dimon and Hughston, Sarmiento, and Boyd and Anderson have attempted to provide stable fixation of fracture by altering the position of fracture fragments. This report is based on 104 cases of trochanteric fractures who were seen and treated at our orthopedic department during the 13 years period from January, 1965 to December, 1978. The study includes clinical and radiologic observation on our series of trochanteric fractures. The results were summarized as follows: 1. Of 104 cases of trochanteric fractures 79 cases occurred in man, 25 cases in woman and each mean age was 51 years in man, 62 years in woman. 2. The most common cause of fracture was due to traffic accident. 3. Among 104 cases, 73 were treated with open reduction and internal fixation, and 31 were treated conservatively. 4. Of fixation devices, Jewett nails were used in 40 cases, Temple University nails in 9 cases, Mclaughlin nail plates in 5 cases, Moore blade plates in 4 cases, Blount blade plates in 3 cases, Thornton nail plates in 2 cases, Neufeld nail plate in 1 case, Richard compression sliding screw plates in 2 cases, plate and screws in 3 cases, Kuntscher nail in 2 cases, and screws in 2 cases. 5. Of 92 cases of trochanterir fractures, 27 cases were stable fracture and 65 cases were unstable fracture. The method of medial displacement of proximal part of distal fragment in 2 cases with unstable fracture and anatomic reduction in 90 cases with stable and unstable fracture were achieved. 6. The average time to fracture union was 16.6 weeks roentgenologically. There was no significant difference in the union rate between the method of treatment. 7. The average time to weight bearing was 11.8 weeks in operative treatment and 18.3 weeks in conservative treatment. 8. Complicatlon after internal flxation were reduced by early ambulation. 9. The method of medial displacement of proximal part of distal fragment of fracture was achieved in 2 cases of unstable fractures, and obtained satisfactory fracture healing, but had disadvantages such as some limitation of motion of the affected hip, shortening of affected extremlty. 10. Satisfactory result was obtained in 95.5% out of operatlve treatment, and 84% out of non-operative treatment. 11. From a consideration of those series, it was concluded that operative treatment of trochanteric fractures offered the advantages of improved function, economy of hospital beds, less complication, and comfort and early ambulatlon of the patient.
Accidents, Traffic ; Aged ; Clinical Study ; Early Ambulation ; Female ; Femur ; Fracture Healing ; Hip ; Hip Fractures ; Humans ; Internal Fixators ; Methods ; Orthopedics ; Pneumonia ; Pressure Ulcer ; Surgeons ; Traction ; Urinary Tract Infections ; Weight-Bearing

Osteosarcoma is the most common primary malignant tumor in the orthopaedic field. Recently, the management of osteosarcoma was evolved in many aspects and the improved results were reported in many articles. The purpose of this study is to evaluate the changes of clinical findings and management modalities in osteosarcoma since 1980. We reviewed 127 osteosarcomas managed from 1980 to 1992. The Enneking surgical stage was as follows; stage I 12 cases, stage II 98 cases and stage III 17 cases. They were subclassified into classic(97 cases), parosteal(12 cases), telangiectatic(5 cases), secondary(4 cases), periosteal(2 cases), gnathic(2 cases), high grade surface(1 cases) and undetermined(4 cases). The disease-free survival rate was evaluated for the patients of stage II classic osteosarcomas treated with amputation(27 cases) or limb-salvage operation(23 cases), and average follow up period of them was 49 months. In 27 cases of amputation adjuvant chemotherapy was administered in 23 cases. And in 23 patients treated with limb-salvage operation, neoadjuvant and adjuvant chemotherapy were done in 19 cases and only adjuvant chemotherapy in 2 cases. The clinical changes since 1980 were as follows: (1) The mean duration from symptom onset to diagnosis was decreased gradually from 6.5 months(1980) to 3.1 months(1992). (2) The proportion of curative surgery was increased from 40%(1980) to 87%(1992) in stage I and II. (3) The proportion of limb-salvage operation was rapidly increased upto 88% since 1985. The 5 year disease-free survival rate of stage II classic osteosarcoma was 36% with amputation and 67% with limb-salvage operation.
Amputation ; Chemotherapy, Adjuvant ; Diagnosis ; Disease-Free Survival ; Follow-Up Studies ; Humans ; Osteosarcoma

No abstract available.
Aorta, Thoracic* ; Blood Flow Velocity* ; Female ; Hypertension, Pregnancy-Induced* ; Pregnancy ; Umbilical Arteries*

No abstract available.
External Fixators* ; Foot Deformities* ; Foot*

No abstract available.

Screw fixation of the tibial component offers advantages in initial fixation in cementless total knee replacement. But the high incidence of screw related osteolysis was reported. The purpose of this study is to evaluate clinical results of cementless total knee replacement and to look for radiographic changes at the screw-bone interface. From January 1988 to December 1991, primary cementless total knee replacements with Miller Galante I (Zimmer, Warsaw. IN) were performed to 53 knees at Kyung Hee university hospital. Among them, 21 cases which could be followed-up for more than 4 years were studied retrospectively about the clinical and radiographic results. The mean follow-up period was 5.5 years(ranged from 4.2 years to 8 years). At the last follow-up period, knee scores of Hospital for Special Surgery were improved from mean 56 points to 90 points and the range of motion from 72 degrees to 110 degrees. In the last follow-up radiographs, osteolysis around screw was classified as linear(type I ), cystic(type II ) and cavitary(type III ) according to the width of the lucency around screws. Among 21 cases, radiographic findings of osteolysis around screw were detected in 10 cases but not in 11 cases. But clinical results were similar between these two groups. Among the total 84 screws(4 screws in each case), 21 screws(25%) showed screw related osteolysis typed as I in 13 screws(15.4%), II in 4 screws(4.8%) and III in 4 screws(4.8%). Among the 13 cases that followed-up more than 6 years, 20 screws(38%) showed screw related osteolysis typed as in 11 screws(21.2%), I in 5 screws(9.6%) and II in 4 screws(7.8%). The most frequently involved site of screw was anteromedial(33.3%). In conclusion, after mean 5.5 year follow-up, the clinical results were satisfactory but the development of osteolysis around screw might be an indicator of the implant failure.
Arthroplasty, Replacement, Knee* ; Follow-Up Studies ; Incidence ; Knee ; Osteolysis* ; Range of Motion, Articular ; Retrospective Studies

No abstract available.
Cerebral Palsy*

STUDY DESIGN: This is a retrospective study evaluating the efficacy of new surgical technique for treatment of fixed lumbosacral kyphosis. OBJECTIVES: To report a new method of vertebral column resection and to determine its efficacy in the treatment of fixed lumbosacral kyphosis. SUMMARY OF BACKGROUND DATA: The treatment of fixed severe spinal deformity is very difficult and only a few surgical methods are reported. The vertebral column resection from anterior and posterior is a radical method to treat the severe deformity but it has many problems with anterior and posterior approachs. MATERIALS AND METHODS: A new surgical method of vertebral column resection from posterior approach only(PVCR) was carried out in 5 patients of fixed lumbosacral Tb kyphosis from October 1997 to March 1998. The mean age was 43.4 years(range 35-61 years), and four were female and one male. The average postoperative follow-up period was 5.5 months(ranged from 2 months to 12 months). An average of 2.6 vertebrae was resected. The degree of sagittal curves was measured using the Cobb technique preoperatively and postoperatively. the rejional lumbosacral kyphotic angle and compensatory thoracic curvature from 74 to 712. The sagittal imbalance was measured by distance from C7 plumb line to postero-superior corner of 51 using 14 x 36 inch standing lateral radiograph. RESULTS: The sagittal deformities were corrected from an average of kyphosis 37.4 to lodosis 8.4 at lumbosacral level and from an average of lodosis 31.6 to lodosis 8.2 at thoracic level. The sagittal imbalance was improved from an average of +11.7cm to +2.2cm, for a posterior immigration of 9.5cm. The mean operating time was 334 minutes and with an average blood loss of 4338m1. Complication comprised of motor weakness with deep wound infection in one case and superficial wound infection in another case. The transient hip flexor weakness was seen in all the patients. The hip flexor power recovered in 3-4 weeks. The patient of motor weakness and deep infection showed partial motor improvement and complete wound healing at last 2 month follow-up. CONCLUSION: one-stage posterior vertebral column resection is a promising technique for treatment of the severe fixed lumbosacral kyphosis.
Congenital Abnormalities ; Emigration and Immigration ; Female ; Follow-Up Studies ; Hip ; Humans ; Kyphosis* ; Male ; Retrospective Studies ; Spine* ; Wound Healing ; Wound Infection

In this study, 47 cases of tuberculous osteitis treated at Severance Hospital from March 1968 to February 1978 were analysed clinically and the following results were obtained.: 1) The sexual incidence was 23 ma1e and 24 female patients. 2) There were 18 cases in the pediatric group and 29 cases in the adult group. 3) The most frequent site was rib (36%), followed by the trochanter of femur (21%) and the proximal portion of humerus (15%). 4) Thirty-seven percent of the cases showed some form of pulmonary tuberculous infiltration. 5) Erythrocyte sedimention rate was increased in 33 cases (70%). 6) The condition was managed medically with triple antituberculosis drugs and surgically with curettage, curettage with bone graft, and partial resection of ribs, etc.
Adolescent ; Adult ; Child ; Child, Preschool ; Female ; Human ; Infant ; Infant, Newborn ; Korea ; Male ; Middle Age ; Osteitis/epidemiology* ; Tuberculosis, Osteoarticular/epidemiology*