1.Experimental study on the effect of phenobarbital on Na+, K+-activated adenosine triphosphatase in microsome fractions of mouse brain.
Seo Kyu KIM ; Sa Jun CHUNG ; Chang Il AHN
Journal of the Korean Pediatric Society 1991;34(7):959-970
No abstract available.
Adenosine Triphosphatases*
;
Adenosine*
;
Animals
;
Brain*
;
Mice*
;
Microsomes*
;
Phenobarbital*
2.A study on Purification of Water Works by Multi-filter Bed Method with Aeration: Application of Biological Oxidation by Aerobic Microorganism.
Yo Han CHUNG ; Jae Kyu MOON ; Heung Kyu JOO ; Hwa Jung SEO
Korean Journal of Preventive Medicine 1972;5(1):43-48
5 bed sand filter, applying biological oxidation, was designed and studied on the treatment of water works. Never using any coagulant agent (drugs), which may cause water pollution in pre-treatment of head water, the author attempt a high rate filtration by the microorganism (nitrofication bacteria) end plant which populate in multi layer sand beds. The result are as follows ; In order to evaluate the oxygen effect on filtration, oxygen was injected in aeration tank attached to each filter tank while filtration, and NH3 was tested as a representative ingredient. It was found out that the aeration method was more effective, with over 33% of NH3 removal capacity, than the anerobic and this 5 bed filter showed double removal capacity of NH3 by comparing with conventional sand bed (2 stage bed). According to the examination of two kind of head water, pre-treated with coagulant agent and activated carben, the filtration capacity was affected by the polluted condition of head water, resulting that lower value of pollution and slower velocity of filtration showed more efficiency of NH3 removal. In this experiment NH3 content tested in treated water had a fairly good correlation with others.
Filtration
;
Head
;
Oxygen
;
Plants
;
Silicon Dioxide
;
Water Pollution
;
Water*
3.A study on Purification of Water Works by Multi-filter Bed Method with Aeration: Application of Biological Oxidation by Aerobic Microorganism.
Yo Han CHUNG ; Jae Kyu MOON ; Heung Kyu JOO ; Hwa Jung SEO
Korean Journal of Preventive Medicine 1972;5(1):43-48
5 bed sand filter, applying biological oxidation, was designed and studied on the treatment of water works. Never using any coagulant agent (drugs), which may cause water pollution in pre-treatment of head water, the author attempt a high rate filtration by the microorganism (nitrofication bacteria) end plant which populate in multi layer sand beds. The result are as follows ; In order to evaluate the oxygen effect on filtration, oxygen was injected in aeration tank attached to each filter tank while filtration, and NH3 was tested as a representative ingredient. It was found out that the aeration method was more effective, with over 33% of NH3 removal capacity, than the anerobic and this 5 bed filter showed double removal capacity of NH3 by comparing with conventional sand bed (2 stage bed). According to the examination of two kind of head water, pre-treated with coagulant agent and activated carben, the filtration capacity was affected by the polluted condition of head water, resulting that lower value of pollution and slower velocity of filtration showed more efficiency of NH3 removal. In this experiment NH3 content tested in treated water had a fairly good correlation with others.
Filtration
;
Head
;
Oxygen
;
Plants
;
Silicon Dioxide
;
Water Pollution
;
Water*
4.Revascularization of occlusive arterial disease in the lower extremity with the transluminal endarterectomy catheter(TEC).
Jae Kyu KIM ; Jeong Jin SEO ; Byung Kwan KOH ; Hyun De CHUNG
Journal of the Korean Radiological Society 1992;28(2):211-214
Revascularizations of 14 occlusive arterial diseases in the lower extremities with the Transluminal Endarterectomy Catheter was done successfully. The causes of occlusions were atherosclerosis in 9 cases and cardiogenic thromboembolism in 5 cases. The site of lesions were at the common femoral artery in 1 case, the superficial femoral artery in 6 cases and the popliteal artery in 7 cases. The length of the lesion were below 5cm(n=3), 5-10cm(n=2), 11-20cm(n=6) and 21-30cm(n=3). Complications were distal embolism(n=1) and hematoma at the puncture site(n=1). No symptoms recurred in any cases during 2 months -15 months followup. Endarterectomy with Transluminal Endarterectomy Catheter was found to be an effective method for revasculizations of occlusive arterial disease in the lower extremity, especially in long segmental occlusion.
Atherosclerosis
;
Catheters
;
Endarterectomy*
;
Femoral Artery
;
Follow-Up Studies
;
Hematoma
;
Lower Extremity*
;
Methods
;
Popliteal Artery
;
Punctures
;
Thromboembolism
5.Effect of Therasonic Lithotripter LT-1000 for Urinary Tract Calculi in Children.
Young Jin SEO ; Sung Kwang CHUNG ; Yoon Kyu PARK
Korean Journal of Urology 1996;37(10):1137-1141
The treatment of urolithiasis in children has been changed dramatically by extracorporeal shock wave lithotripsy (ESWL) and endourological procedure in recent years. Especially, the use of extracorporeal shock wave lithotripsy has changed the place of open surgery in the treatment of urinary stones in children. A total of 24 children with 25 renoureteral units underwent treatment with Therasonic Lithotrirter System for urinary tract stones between Feb. 1992 and March 1996. The patient age ranged from 3 months to 14 years with a mean of 4.7 years. The location of stones were renal in 9, upper ureter in 6, and lower ureter in 10 cases. The average stone length was 14mm with a range of 5mm to 50rnm. Developmental anomalies of the urinary tract were noted in 2 children, and there were the incomplete duplicated ureter and the ureterocele. The excreted stones in 5 children were analysed biochemically and calcium oxalate stones were present in 3 cases, calcium phosphate stone in 1 and cystine stone in 1. A complete stone free rate was achieved in 91.7%. Except for one case, no specific complication occurred during or after treatment, but perioperative antibiotic prophylaxis was done Therefore, the authors conclude that extracorporeal shock wave lithotripsy is a safe and effective method for the treatment of urinary stones in children.
Antibiotic Prophylaxis
;
Calcium
;
Calcium Oxalate
;
Calculi*
;
Child*
;
Cystine
;
Humans
;
Lithotripsy
;
Shock
;
Ureter
;
Ureterocele
;
Urinary Calculi
;
Urinary Tract*
;
Urolithiasis
6.Molecular Cloning of hSC2 Encoding 5α-reductase-like Protein.
Ho Chul SEO ; Do Won KIM ; Moon Kyu KIM ; Jung Chul KIM ; Sang Lip CHUNG
Annals of Dermatology 2000;12(4):252-258
BACKGROUND: The human homologue of the SC2 gene from a human dermal papilla cell cDNA library has been isolated and designated hSC2. HSC2 protein also shares similarity with 5 -reductase, a protein important in testosterone metabolism. OBJECTIVE: Prior to knowing the functions of hSC2 in dermal papilla, we cloned it and analyzed its relative expression levels in adult tissues and cancer cell lines. METHODS: hSC2 was isolated from low abundant clones in dermal papilla cDNA library using cDNA array hibridization method. Full-length clone was sequenced and we studied its expression in different tissues by Northern blot hybridization. RESULTS: Sequence data reveals a single open reading frame, encoding a putative hydrophobic protein with a calculated molecular weight of 36 kDa. Its deduced amino acid sequences are almost 97.4% identical to t4ose of rat protein. Northern blot hybridization shows that hSC2 cDNA recognizes a 1.35 kb transcript that was expressed in various epithelial and mesenchymal tissues including testis and liver. CONCLUSION: We have cloned and analysed tissue distributions of hSC2. It was interesting that it had homology with 5α-reductase isozymes. Further studies will be needed to understand the involvement of hSC2 in androgen hormone signaling.
Adult
;
Amino Acid Sequence
;
Animals
;
Blotting, Northern
;
Cell Line
;
Clone Cells
;
Cloning, Molecular*
;
DNA, Complementary
;
Gene Library
;
Humans
;
Isoenzymes
;
Liver
;
Metabolism
;
Molecular Weight
;
Oligonucleotide Array Sequence Analysis
;
Open Reading Frames
;
Rats
;
Testis
;
Testosterone
;
Tissue Distribution
7.Surgical Management of Ureteropelvic Junction Obstruction in Children.
Hyeok Jun SEO ; Sung Kwang CHUNG ; Yoon Kyu PARK
Korean Journal of Urology 1997;38(11):1190-1195
From January 1988 to January 1996, 42 infants and children (44 renal units) had undergone surgical management to correct ureteropelvic junction obstruction. Median patient age was 8.5 years (range from 2 months to 17 years) and 11 patients were less than 1 year old at operation. Of 44 renal units surgically managed, 30 were on the left side and 10 were right side. 2 patients had undergone bilateral surgical management. Presenting symptoms were febrile urinary tract infection in 14 cases, abdominal pain in 14 cases, abdominal mass in 5 cases, gross hematuria in 3 cases and 3 cases were detected prenatally. We used imaging antegrade pyelography (AGP) in 15 cases, additional retrograde pyelography (RGP) in 12 cases and both AGP and RGP were performed in 1 case. To correct ureteropelvic junction obstruction, we performed dismembered pyeloplasty in 33 renal units, ureterolysis in 2 renal units, ureterocalycostomy in 1 renal unit, endopyelotomy in 1 renal unit and nephrectomy in 7 renal units. To diverge the urinary flow, we used nephrostomy in 19 renal units, ureteral stenting in 6 renal units and both nephrostomy and ureteral stenting were used in 10 renal units. As postoperative complications, restenosis was developed in 5 renal units, delayed open in 5 renal units, urinary tract infection in 2 renal units and wound infection, prolonged urine leakage, ureteral stone in each 1 renal unit. Postoperative success rate in followed-up patients, who had undergone pyeloplasty, was 91.6%. The success rate in children, who was less than 1 year old, was 100% and in children, who was more than 1 year old, was 88.4%. Finally we suggest that the surgical correction is safe and proper method for ureteropelvic junction obstruction in children. Additionally early operation of ureteropelvic junction obstruction is recommendable.
Abdominal Pain
;
Child*
;
Hematuria
;
Humans
;
Infant
;
Nephrectomy
;
Postoperative Complications
;
Stents
;
Ureter
;
Urinary Tract Infections
;
Urography
;
Wound Infection
8.The Effect of Diphenylcyclopropenone Immunotherapy on Molluscum Contagiosum.
Kyu Han KIM ; Koo Il SEO ; Jin Ho CHUNG ; Kyung Chan PARK ; Hee Chul EUN
Annals of Dermatology 1993;5(2):79-82
BACKGROUND: Contact immunotherapy using diphenylcyclopropenone (DPCP) has been used in the treatment of alopecia and warts. DPCP seemed to be a promising agent for viral disease including molluscum contagiosum (MCI). OBJECTIVE: The purpose of this study was to evaluate the effect of DPCP immunotherapy on MC in children. METHODS: Twenty three patients with multiple lesion of MC were treated with DPCP immunotherapy. RESULTS: Twelve patients (52.2%) showed cure, and eleven patients (47.8%) showed treatment failure. No severe side effects were seen. CONCLUSION: DPCP immunotherapy may be an effective treatment in children with MC without serious side effects.
Alopecia
;
Child
;
Humans
;
Immunotherapy*
;
Molluscum Contagiosum*
;
Treatment Failure
;
Virus Diseases
;
Warts
9.A Case of Pulmonary Blastoma.
Kang Seo PARK ; Kyu Sun CHOI ; Kyong Nyong KIM ; Wan Soeb KIM ; Kwang Min LEE ; Dong Kyu CHUNG
Journal of the Korean Pediatric Society 1990;33(10):1447-1453
No abstract available.
Pulmonary Blastoma*
10.Antihypertensive Effect of Low-Dose Clonidine Monotherapy.
Jung Don SEO ; Jong Sung KIM ; Chung Kyun LEE ; Un Ho RYOO ; Ock Kyu PARK ; Soon Kyu SUH
Korean Circulation Journal 1985;15(4):639-644
The antihypertensive effect of clonidine was evaluated in 129 patients with essential hypertension of mild to moderate severity with a dosage of one tablet(0.075mg) a day for 71 patients of Group I and two tablets a day for 58 patients of Group II. The results were as follows : 1) Of 71 patients of Group I, 34 patients(47.9%)showed good antihypertensive effect(greater than 15 mmHg drop in mean diastolic pressure) and 11 patients(15.5%) showed fair effect(10-14 mmHg drop in mean diastolic pressure). 2) Of 58 patients of Group II, 39 patients(67.2%) showed good effect and 7 patients(12.1%) showed fair effect. 3) The side effect observed was transient and tolerable dry mouth, which developed in 5.6% of Group I patients and 13.6% of Group II patients.
Clonidine*
;
Humans
;
Hypertension
;
Mouth
;
Tablets