No abstract available.
Temporomandibular Joint Disorders*

Aplasia cutie congenita is a rare congenital disease showing focal abscence of skin. In the msjority of instances it is limited ta the scalp especially on the vertex although other areas of the body may also be involved. Other congenital malformation have been reported to ccur with ACC odcasionally. Diagnosis depends on primarily clinical findings. The histologic finding virious from an absence of appendages to the involvement of varying layers of skin, occasionally extending to the bane or dura. Healed lesions often demonstrate a flattened epidermis, a proliferation of fibrobasts in a loose connective tissue stroma, newly formed capillaries, and a complete absence of adnexa stuctures. We observed a newborn infant with aplssia cutis congenita. The akir, defect was found on the posterior fontanelle. No associating cangenital anomalies were found in this case.
Capillaries ; Connective Tissue ; Cranial Fontanelles ; Diagnosis ; Ectodermal Dysplasia* ; Epidermis ; Humans ; Infant, Newborn ; Scalp ; Skin

Phakomatosis pigmentovascularis is characterized by the coexistence of pigmentary nevus and hemangioma. Since the term was first described by Ota et al in 1947, about 80 cases have been reported in the literature. In 1979, Hasegawa et al subclsssified the disorder into eight types : type I, nevus flammeus and nevus pigmentosus et verrucosus, type II, nevus flamme is and dermal melanocytosis, type III nevus flammeus and nev.us spilus, type IV, nevus flammeus, dermal melanocytosis and nevus spilus. Each type is subdivided into localized(a) and systemic(b) types, A 25-year-old male had brown papules on the left knee and thigh and purple patches on the left leg that had been present for approximately 7 years. He had no concon ittant systemic disease. The histopathologic findings on brown papules and purple patches are compatible with epidermal nevus and nevus flammeus respectively. We herein report a case of phakomatosis pigmentovascularis type I a.
Adult ; Down Syndrome ; Hemangioma ; Humans ; Knee ; Leg ; Male ; Neurocutaneous Syndromes* ; Nevus ; Port-Wine Stain ; Thigh

Intraspinal tumors in children are of especially interest to orthopaedic surgeons for two reasons; First, musculoskeletal abnormalities, are often treated for long periods before the correct diagnosls is suspected; Second, important orthopaedic problems are encountered in almost everychild treated for intraspinal tumor, not only during the immediate postoperative management but all through subsequent growth. We report a case presentation of the intraspinai tumor, dermoid cyst, successfully treated with operation.
Child ; Dermoid Cyst ; Humans ; Musculoskeletal Abnormalities ; Surgeons

We report herein a case of the coexistence of linear and placue porokeratosis in a 20-year-old female patient. The patient showed the typical clinical picures of linear and plaque porokeratosis on the right wrist, dorsum of the hand, dorsolater; I aspect of the fingers and axilla, respectively. Histopathologically, these lesions showed the typical cornoid lamella. We tried to remove the lesions with 75 100% trichloroacctic acid but could not gain a sat.isfact.ory effect.
Axilla ; Female ; Fingers ; Hand ; Humans ; Porokeratosis* ; Wrist ; Young Adult

A case of multiple trichilemmal cysts (TC) is presented. TC is known to be a kind of keratinous cyst with lining cells showing trichilemmal keratiniration. A 63-year-old female patient presented with a 30 year duration of increasing in size and number of twenty five nodular lesions on the scalp. All twenty five TC on the scalp were totally excised and examined microscopically. However, the evidence of proliferation or malignant change like the previous case reports was not found in our case.
Female ; Humans ; Middle Aged ; Scalp

Electrocorticograms were recorded in cases with cases with epilepsies following procainization and eletrocoagulation of limited areas of cerebral cortex. Procainizaion of preoccipital cortical area, Brodmann's area 19, causes suppression of epileptiform discharge in the rest or ipsilateral cerebral hemisphere, motor, sensory and temporal areas. Conversely no suppression of electrical activity was observed in preoccipital leads following procainization of motor, senory or temporal areas. Electrocoagulation of preoccipital area also produced a regression of the abnormal cortical activities in the motor, sensory and temporal areas, which was the phenomenon identical with that following procainization of preoccipital area, and lasted weeks and months along with clinical improvement in symptomatology of epilepsy. Fifty-one cases of intractable epilepsy were treated surgically by the coagulation of preoccipital areas which were exposed through skull trephine hole with perforator in D'Errico trephine. It was noteworthty to emphasize that progressive normalization of electroencephalographic records of patients was obtained in months or years after the preoccipital coagulation. The surgical treatment of epilepsy in fifty-one cases was associated with freedom from seizures in three cases and clinical improvement in thirty-none cases. The purpose of surgical intervention upon preoccipital area was mainly based on blocking and suppressing the abnormal excessive neuronal discharge passing or spreading through the preoccipital cortical area over the rest of ipsilateral cerebral hemisphere.
Cerebral Cortex ; Cerebrum ; Electrocoagulation ; Epilepsy* ; Freedom ; Humans ; Neurons ; Seizures ; Skull

BACKGROUND: Superoxide disrnutase(SOD) is an essential enzyme oi protective defense mechanism in cellular compartments against the potential cytotoxicity of superoxileinion. It seems SOD activity is increased in psoriasis because of an increase in oxygen intermediates dae to hyperoxia. However SOD activity is decreased paradoxically. OBJECTIVE: In order to understand the pathophysiology of psoriasis and to elucidate the significance of SOD aetivity in keratinocyte proliferution, we measured the SOD activities in psoriatic and in normal skin. METHODS: Authors assayed the level of SOD activities in 16 psoriatie and 16 normal skin specimens, which were obtained from face/neck (1and 4 speeimens), forearm(5 and 4 specimens), trunk(6 and 3 specimens), and lower extremiy(4 and 5 specimens). We also investiga.ed changes of SOD activity by age and regional differences of' SOD sctivities in the psoriatic and normarl skins. RESULT : First, activities of tot,al SOE Mn-SOD and Cu, Zn-SOD were L2.75+8.15, 4.28+ 3.62, 8.48+ 6.37 units/mg protein respect,ively in the psoriatic skin. Activities of toal SOD, Mn-SOD and Cu, Zn- SOD were 17.63+9.10, 3.38+ 1..85, 1.25+8.16 units/mg protein respec,ively in the normal skin. There was a significant differenc between psoriatic and normal skins in C-SOD activity(p<0.05). Second, the changes of total SOD, Mn-FOD and Cu, Zn-SOD activities showed no significant differences between the age groups. Third, in sun exposed area and unexposedire there were no significant differences between the psoriatic and normal skins in SOD activities. Elut in the normal skin, there were significant differences between sun exposed area and unexposed area in total SOD and Cu, Zn-SOD activities. CONCLUSION: There is a signiificant difference between psoriatic and normal skins in Cu, Zn-SOD activity. Namely, the Cu, Zn-SOD activity is significantly decreased in psoriasis.
Epidermal Cyst* ; Humans ; Hyperoxia ; Keratinocytes ; Oxygen ; Psoriasis ; Skin ; Solar System ; Superoxide Dismutase ; Superoxides

BACKGROUND: Androgens stimulate the growth of hair in various are of skin including the pubis, axilla and beard, whereas in the scalp androgens promote baldness in genitically predisposed individuals. Androgens bind to specific intracellular receptors, which modulate saecific gene expression and so affect hair loss. Androgenetic isldness is first apparent on the frontalegion, with recession of the hair line. As this progresses, aloperia also develops on the vertex. But the osterior and lateral scalp area is spared, even in the most advanced eases, and even in old age. OBJECTIVE: The purpose of our study is to find out the difference of androgen receptor expression in lesional and non lesional scailp of androgenetic alopecia patients by iminunohistochemical staining. METHODS: Biopsy specimens were taken from its lesion(vertex) and its non lesion(occiput) of 3 patients with androgenetic alopecia and 4 normal controls. The deteatic n of androgen receptor was performed by an immunohistochemical technique(streptavidin peroxidasc method) using monoclonal antibody against androgen receptor. RESULTS: Androgen receptors were strongly expressed in eccrine land and sebaceous gland, and weakly expressed in epidermal cells, hair infundibulum, hair bulb epith-lium and dermal hair papilla. CONCLUSION: There was no significant difference of the expression if androgen receptors in lesional and non lesional scalp of androgenetic alopecia.
Alopecia* ; Androgens ; Axilla ; Biopsy ; Gene Expression ; Hair ; Humans ; Receptors, Androgen* ; Scalp* ; Sebaceous Glands ; Skin

"Dual LAD" was defined as the early bifurcation of the proximal LAD into two vessels : a short LAD which remained in the anterior interventricular sulcus and does not reach the apex, and a long LAD which leaves the anterior interventricular sulcus only to return to the distal sulcus and continue to the apex. Recognition of "Dual LAD" is essential to prevent errors of interpretation of the coronary arteriogram and for planning of optimal surgical therapy. We report 2 cases of "Dual LAD" with the review of the literatures.
Coronary Vessels*