A 28-year-old male patient is described who developed multiple erythematous nodules and papules on the face, upper chest, back, upper and lower extrimities, leading to extensive ia.filtration of the skin and lymph nodes. Histology from the involved lymph node and skin nodule revealed widely scattered patchy infiltration of abnormal. hyperchromatic polymorphous histiocytes in the dermis. The patient died at about 8 months after onset of the disease, in spite of antineoplastic treatment.
Adult ; Dermis ; Histiocytes ; Humans ; Lymph Nodes ; Lymphoma* ; Male ; Skin ; Thorax

An asymptomatic 26-year-old man was initially admitted with a suspicious mediastinal mass. On the basis of the contrast-enhanced chest CT findings, aneurysm formation involving the left cervical aortic arch associated with subaortic left innominate vein was diagnosed. The aneurysm was confirmed by MR angiography and DSA. The arch aneurysm was surgically removed. We describe this case, and review the literature.
Adult ; Aneurysm* ; Angiography ; Aorta, Thoracic* ; Brachiocephalic Veins* ; Humans ; Tomography, X-Ray Computed

No abstract available.
Female ; Humans ; Pregnancy ; Pregnancy Trimester, Second*

PURPOSE: To compare the decentration, tilt and anterior chamber depth between aspheric AcrySof(R) IQ IOL (SN60WF) and spheric AcrySof(R) Natural IOL (SN60AT). METHODS: The subjects of this study consisted of 22 patients (26 eyes) using an aspheric AcrySof(R) IQ IOL and 26 patients (31 eyes) using spheric AcrySof(R) Natural IOL. All lenses were inserted into the capsular bag after 5 mm continuous curvilinear capsulorhexis and phacoemulsification. The decentration, tilt and anterior chamber depth of both IOLs were measured on the 1st, 30th and 60th postoperative day using an anterior eye segment analysis system (Scheimpflug camera, EAS-1000, Nidek, Japan). RESULTS: There was no statistically significant difference in the decentration between the IQ IOL and Natural IOL on the 1st (p=0.05), 30th (p=0.09) and 60th (p=0.06) postoperative day. There was a statistically significant difference in tilt between IQ IOL and Natural IOL on the 1st (p=0.000053) and 30th (p=0.018) postoperative day. However, there was no statistically significant difference in tilt on the 60th postoperative day (p=0.05). The anterior chamber depth of IQ IOL was decreased, but was not statistically significant on the 1st (p=0.10), 30th (p=0.07) or 60th (p=0.06) postoperative day. CONCLUSIONS: There were no significant differences between AcrySof(R) IQ IOL and AcrySof(R) Natural IOL in decentration, tilt or anterior chamber depth, showing that posterior aspheric surface causes little effect on the IOL stability.
Anterior Chamber ; Anterior Eye Segment ; Capsulorhexis ; Humans ; Lenses, Intraocular ; Phacoemulsification

Human papillomavirus (HPV) 16/18 is a causative agent of uterine cervical carcinoma. HPV 16/18 can alter cell cycle regulation through apoptosis. Bcl-2 is an important regulatory gene of apoptosis. A study was done to evaluate the relation between HPV 16/18 and bcl-2 and apoptosis in 21 cases of carcinoma in-situ (CIS), 5 cases of microinvasive carcinoma and 23 cases of invasive squamous cell carcinoma. HPV 16/18 was detected by hybrid capture system (HCS), bcl-2 protein by immunohistochemical method and apoptosis by using the hematoxylin-eosin stained slide. The results were as follows: Expression of the bcl-2 protein was 43% (9/21) in CIS and 26% (6/23) in invasive carcinoma. Expression of the bcl-2 protein was 42% (5/12) in CIS with HPV 16/18 infection, 44% in CIS without HPV 16/18 infection, 20% (2/10) in invasive carcinoma with HPV 16/18 infection and 31% (4/13) in invasive carcinoma without HPV 16/18 infection. Mean apoptotic index (mAI) was 3.36 in CIS, 5.23 in microinvasive and 6.25 in invasive carcinoma. mAI was 3.66 in CIS with HPV 16/18 infection, 2.86 in CIS without HPV 16/18 infection, 6.18 in invasive carcinoma with HPV 16/18 infection and 6.30 in invasive carcinoma without HPV 16/18 infection. Based on these results, we conclude that there are no correlation between HPV infection and bcl-2, and between HPV infection and apoptosis in invasive and in situ carcinoma of the uterine cervix, and apoptosis is increased according to tumor progression.
Apoptosis* ; Carcinoma, Squamous Cell* ; Cell Cycle ; Cervix Uteri* ; Female ; Genes, Regulator ; Humans

To investigate the relationship of the density change of lens nucleus and cortex with anterior chamber depth and lens thickness, we measured the anterior chamber depth, density and length of lens nucleus and cortex of 312 eyes with a Scheimpflug camera. The mean values of density of lens nucleus and cortex were 108.45+/-46.33CCT and 27.74+/-13.76CCT, respectively. The mean values of the thickness for both were 2.85+/-0.54mm and 1.29+/-0.46mm, respectively. The mean value of anterior chamber depth was 2.93+/-0.49mm. The densities of lens nucleus and cortex were increased significantly with aging, but lens thickness and anterior chamber depth were decreased. The value of anterior chamber depth changes and lens thickness changes were more rapid especially in the 5th and 7th decades compared with other groups(P<0.01), and more rapaid in the density group(100~150CCT) than other group in changing densities(P<0.05), and they were highly correlated with anterior cortex, posterior cortex, nucleus in order at each portion of lens. Both anterior chamber depth changes and lens thickness changes were more rapid in the lens cortex than those in the lens nucleus.
Aging ; Anterior Chamber*

To study the frequency of the most common organisms according to culture sites, age, antibiotic sensitivity and resistance, we researched the medical records of the patients for the past 5 years who had ever been treated for infectious ocular disease. Total 19 strains and 226 bacterial organisms were cultured in 207 eyes. Most common organism was staphylococcus(37.6%). The overall percentage of gram-positive organisms showed 61.9% and that of gram-negative 38.1%. According to age, the most common organism was staphylococcus in neonatal period, streptococcus in the age from 1 to 10 and over 60, pseudomonas in the age from 21 to 30 and 41 to 50. The common organisms according to the culture site were staphylococcus in conjunctiva, staphylococcus and streptococcus in punctum, staphylococcus and pseudomonas in cornea, and staphylococcus in vitreous. The antibiotic sensitivity test of gram-positive organisms showed sensitivity more than 90% and rare resistance to ofloxacin and vancomycin. Gramneganisms showed sensitivity more than 80% to ofloxacin and resistance less than 30% to tobramycin. Ofloxacin showed high sensitivity and low resistance to all of the gram-positive and negative organisms. According to culture sites, it was vancomycin in conjunctiva and punctum, ofloxacin in cornea, and ciprofloxacin in vitreous that showed relatively high sensitivity and low resistance. Though it is necessary to culture and test antibiotic sensitivity in treating the ocular disease, it seemed effective as primary therapeutic agents to use appropriate antibiotics based on the clinical findings before the test results are reported. Periodic culturing of causative organisms and testing the antibiotic sensitivities would be helpful in selecting the effective antibiotics for treatment and reducing abuse of antibiotics.
Anti-Bacterial Agents ; Bacterial Infections* ; Ciprofloxacin ; Conjunctiva ; Cornea ; Drug Resistance, Microbial ; Humans ; Medical Records ; Ofloxacin ; Pseudomonas ; Staphylococcus ; Streptococcus ; Tobramycin ; Vancomycin

We report two cases of hyalinizing trabecular carcinoma (HTC) of the thyroid gland. These two patients were euthyroid women aged 36 and 65 years of age. The tumors were encapsulated and measured 0.8 and 4.0 cm in diameter, respectively. Histologically, the tumors were composed of a compact proliferation of cells in a lobular and trabecular pattern with an intervening hyalinized, fibrotic vascular stroma. Occasionally the cells were arrayed in microfollicles. Multiple and serial sections showed cords of tumor cells invading into the capsule in both cases and vascular invasion in one case. These findings suggested that HTCs are a malignant counterpart of hyalinizing trabecular adenoma, similar to conventional follicular tumor. Positive immunostaining of tumor cells for thyroglobulin and negative staining for high molecular weight cytokeratin, cytokeratin 19, neuron specific enolase, chromogranin, and synaptophysin allowed distinction from medullary carcinoma. Even though HTCs are an heterogeneous group of tumors, the present two cases are probably variants of follicular carcinoma rather than papillary carcinoma.
Adenoma ; Carcinoma, Medullary ; Carcinoma, Papillary ; Female ; Humans ; Hyalin* ; Keratin-19 ; Keratins ; Molecular Weight ; Negative Staining ; Phosphopyruvate Hydratase ; Synaptophysin ; Thyroglobulin ; Thyroid Gland*

Although the incidence of tuberculosis in Korea in general has declined in recent years, it remains an importat health problem, especially in children. Inspite of the recent controversy over the necessity of tuberculin skin test prior to measles vaccination, this brief report shows 13.8% of positive skin test at 9 and 15 months of age at the time of measles vaccination. We feel, in Korea, practicing tuberculin skin test prior to measles vaccination is good way of detecting asymptomatic infection in young age who needs preventive therapy.
Asymptomatic Infections ; Child ; Humans ; Incidence ; Korea ; Measles* ; Skin Tests* ; Skin* ; Tuberculin* ; Tuberculosis ; Vaccination*

The purpose of this study was to compare the nutrient intake and diet quality of postmenopausal osteoporotic women to those of control subjects, and to investigate the relationship among diet quality and bone mineral density in postmenopausal women. In this study, we classified the subjects into the postmenopausal osteoporotic women (n = 38) and control (n = 43) according to their lumbar spine bone mineral density and age. Dietary intakes, anthropometric measurements and dietary quality indices were measured and evaluated. The average age of osteoporotic and control group were 60.4 yrs and 58.3 yrs, respectively and there was no significant difference. Body weight, body mass index of osteoporotic group were significantly lower than those of control group. The average energy intake of osteoporotic and control group were 1243.3 kcal and 1475.8 kcal, respectively and there was a significant difference. The osteoporotic group consumed significantly lower quantities of protein, plant protein, vitamin A, vitamin B1, vitamin B2, folate, vitamin C, calcium, animal calcium, plant calcium, iron and zinc compared to the control group. The osteoporotic group consumed significantly lower of food, vegetables, mushrooms, fruits intakes compared to the control group. In the diet quality, protein, vitamin A, vitamin B1, vitamin B2, folate, vitamin C, calcium, iron, Zinc nutrient adequacy ratio (NAR) of osteoporotic group were significantly lower than that of control group. Mean adequacy ratio (MAR) of osteoporotic and control group were 0.63 and 0.78, respectively and there was significant difference. To evaluate nutrient density, Index of nutritional quality (INQ) was calculated by dividing nutrient content per 1,000 kcal of diet with RDA per 1,000 kcal. The average dietary variety score (DVS) of osteoporotic and control group were 22.4 and 33.2, respectively and there was significant difference. DVSs of pulses (p < 0.01), seeds (p < 0.01) and vegetables (p < 0.05) in osteoporotic group were significantly lower than those of the control. In conclusion, postmenopausal osteoporotic women had lower protein, vitamin A, folate, vitamin C, calcium, iron zinc intake quality and vegetables, mushrooms, fruits DVSs than those of the control. Therefore, to promote skeletal health enough energy and food should be consumed, and the maintenance of vitamin and mineral balance by increasing of vitamin A, folate, vitamin C, calcium, iron of intakes are very important.
Agaricales ; Animals ; Ascorbic Acid ; Body Mass Index ; Body Weight ; Bone Density ; Calcium ; Diet* ; Energy Intake ; Female ; Folic Acid ; Fruit ; Humans ; Iron ; Nutritive Value ; Plants ; Riboflavin ; Spine ; Thiamine ; Vegetables ; Vitamin A ; Vitamins ; Zinc