Purpose of this study is to find out proper means of estimating the urinary mercury excretion the normal individuals. Whole void volume was collected every 2 hours beginning from 6 o'clock in the morning until 6 o'clock next morning. Mercury excretion in each urine specimen was measured by NIOSH recommended dithizone colorimetric method (Method No. : P & CAM 145). Urinary concentration of mercury was adjusted by two means : specific gravity of 1.024 and a gram of creatinine excretion per liter of urine comparing the data with the unadjusted ones. Mercury excretion in 24-hour urine specimen was calculated by adding the amounts measured with the hourly collected specimens of each individual. Statistical analysis of the urinary mercury excretion revealed the following results : 1. Frequency distribution curve of mercury excreted in urine of hourly specimens was best fitted to power function expressed in the form of y=ax(b), Adjustment of the urinary mercury concentration by creatinine excretion was shown to be superior (y=1674x(-1.52)), r(2)=0.95) over nonadjustment(y=2702x(-1.57)), r(2)=0.92) and adjustment by specific gravity of 1.024(y=4535x(-1.66), r(2)=0.93). 2. Both log-transformed mercury excretion in hourly voided specimens and mercury excretion itself in 24 hour specimens showed the normal distributions. 3. The frequency distribution of mercury adjusting the urinary concentration of mercury by creatinine excretion was best fitted to a theoretical normal distribution with the sample means and excretion was best fitted to a theoretical normal distribution with the sample means and standard deviation than those unadjusted or adjusted with specific gravity of 1,024. 4. Average urinary mercury excretions in 24-hour urine specimen in an individual were as follows : a) Unadjusted urinary mercury excretions. mean and standard deviation :18.6+/-13.68 microgramHg/liter. median : 16.0 microgramHg/liter. range : 0.0-55.10 microgramHg/liter. b) Adjusted with specific gravity. mean : 20.7+/-11.76 microgramHg/liter x 0.024/(S.G.-1.000). median : 20.7 microgramHg/liter x 0.024/(S.G.-1.000). range : 0.0-52.9 microgramHg/liter x 0.024/(S.G.-1.000). c) Adjuested with creatinine excretion. mean and standard deviation : 10.5+/-6.98 microgramHg/g creatinine/liter. median : 9.4 microgramHg/g creatinine/liter. range : 0.0-26.7 microgramHg/g creatinine/liter. 5. No statistically significant differences were found between means calculated from 24-hour urine specimens and those from hourly specimens transformed into logarithmic values. (P<0.05).
Creatinine ; Dithizone ; Gravitation ; National Institute for Occupational Safety and Health (U.S.) ; Specific Gravity

No abstract available.
Mastocytoma* ; RNA, Antisense*

An aberrant right subclavian artery, the most common congenital anomaly of the aortc arch, is rarely symptomatic during the infancy, if an anomalous origin of a right common carotid artery is also associateda varient of innomiate artery compression syndrome. We experienced a case of an aberrent right subclavian artery associated with an anomalous origin of the right common carotid artery in a female newborn, who showed severe respiratory distress soon after birth. The diagnosis was confirmed by aortogram and operative findings. the ligature and section of the aberrent right subclavian artery resulted in improvement of respiratory distress. A brief review of the related literature is also presented.
Arteries ; Brachiocephalic Trunk* ; Carotid Artery, Common ; Diagnosis ; Female ; Humans ; Infant, Newborn ; Ligation ; Parturition ; Subclavian Artery*

No abstract available.
Enterococcus*

No abstract available.
Histiocytosis*

No abstract available.
Busan* ; Cytogenetics*

A total of 200 cases of metastatic bone tumors was treated at the Yonsei Medical Center during the 5 years period from January 1976 to December 1980. The results of clinical radiological and pathologic analysis are as followings. 1. Among 200 cases of metastatic bone tumors, common site of cancer comprised the lung (30.5%), breast (15.0%), uterus (8.5%), stomach (6.4%), thyroid (3.5%), liver (3.5%), kidney (3.5%), nasopharynx (3.0%), and prostate (2.0%). In male, common primary sites of cancer were lung, stomach, kidney, oropharynx in decreasing order of incidence and in female, breast, uterus and lung. 2. In metastatic bone tumors, 75.5% were observed in the age group between 41 and 70 year of age, and average age was 53.1 years. 3. The sex distribution was 107 males (53.1%) and 93 females (46.5%). 4. The bones affected most frequently in this series were as followings; In only 9 cases (4.5%), metastasis to bone distal to the elbows and knees occurred. 5. Clinical features in this series were classified according to various conditions. Bone pain noticed on 163 cases (81.5%), fatigue on 152 cases (76.0%) and weight loss on 128 cases (64.0%). 6. Pathologic fractures occurred on 22 cases (11.0%); among them, 13 cases on the femur, 5 cases on the vertebrae, and 1 case on the acetabulum, humerus, rib and clavicle respectively. 7. Hematologically, serum calcium and phosphorus was noticed within normal limits. Serum alkaline phosphatase was slightly elevated and serum acid phosphatase was elevated in all cases of prostatic carcinoma. Serum albumin/ globuline ratio was slightly reversed (3.4/3.5mg%). 8. Radiologically, 86 cases were osteolytic, 10 cases were osteoblastic and 44 cases were mixed type. False negative on X-ray examination with positive finding of scan with 99mTc-MDP were found in 17 cases (27.4%). 9. All cases was treated by various methods; among this series, radiation and chemotherapy performed in 57 cases, radiation in 49 cases, chemotherapy in 14 cases, hormone therapy in 16 cases and radioisotope therapy in 5 cases. For 22 pathologic fractures, conservative treatment was performed in 9 cases, open reduction and internal fixation in 13 cases, open reduction and internal fixation with acrylic cement in 5 cases.
Acetabulum ; Acid Phosphatase ; Alkaline Phosphatase ; Breast ; Calcium ; Clavicle ; Drug Therapy ; Elbow ; Fatigue ; Female ; Femur ; Fractures, Spontaneous ; Humans ; Humerus ; Incidence ; Kidney ; Knee ; Liver ; Lung ; Male ; Nasopharynx ; Neoplasm Metastasis ; Oropharynx ; Osteoblasts ; Phosphorus ; Prostate ; Ribs ; Sex Distribution ; Spine ; Stomach ; Technetium Tc 99m Medronate ; Thyroid Gland ; Uterus ; Weight Loss

Cubitus varus deformity caused usually by malunion in supracondylar fracture or epiphyseal injuries of the elbow joint, but the other causes of cubitus varus deformity have not been reported. 7 cases of cubitus varus deformity were found among the patients in Sam Yook Childrens Rehabilitation Center in Oct. 1981 all of whom used crutches in order to ambulate due to late sequele of poliomyelitis. The results were as follows. l. After long-term crutch walking, cubitus varus deformity and bowing around the proximal forearm were seen among the patients who mis-used the crutches. 2. Gross carrying angle was greater than radiographic carrying angle and it caused by hypertrophy of the extensor muscle group in forearm and bowing around the proximal forearm. 3. Etiologic factors of the cubitus varus deformity were considered to be improper measurement of the crutches, degree of paralysis of lower extremity and duration of the crutch walking, etc. 4. The mechanism of this deformity could be explained biomechanically by the abnormal axial loading onto the elbow following long-term crutch walking. 5. The correct measurement of the crutches and proper flexion of the elbow during crutch walking were stressed.
Child ; Congenital Abnormalities ; Crutches ; Elbow ; Elbow Joint ; Forearm ; Humans ; Hypertrophy ; Lower Extremity ; Paralysis ; Poliomyelitis ; Rehabilitation Centers ; Walking

Metastatic bone tumors can lead to development of pathological fractures which may cause incessant pain. Hypercalcemia and hypercalciuria may develop secondary to skeletal metastasis and recumbency, leading to death from cardiac and renal sequeale. The proper surgical treatments of the metastatic bone tumor offer many advantages in relief of pain, simplifying nursing care, restoring resonable mobility and prevent complications. The authors reviewed 24 cases of metastatic bone tumors which received surgical treatment at Severance Hospital from January 1976 to March 1982. The results were obtained as follows: 1. Twenty four among three hundred patients with metastatic bone tumors were treated surgically. 2. There was no sexual preference and 66.7% were observed in the age of 51 to 70 group. 3. The most common site of operation was the femur. 4. The methods of operation were as follows: Resectionoflesion.....................5 Replacement with prosthesis..........3 Open reduction and internal..........10 Spinal fusion..........................2 Laminectomy............................4 5. All cases had received various types of ancillary treatment: radiation in 8 cases, 131I radioactive isotope in 1 case, chemotherapy in 2 cases, hormone therapy in 1 case, radiation and chemotherapy in 3 cases and conservative pain control in 9 cases. 6. Among the 15 followed cases, nine survived more than 6 months and 3 cases longer than 1 year after surgery. The pain was relieved markedly in twenty-three patients, and ambulated well with brace support.
Braces ; Drug Therapy ; Femur ; Fractures, Spontaneous ; Humans ; Hypercalcemia ; Hypercalciuria ; Neoplasm Metastasis ; Nursing Care

These radiologic studies were carried out on 265 cases of silicosis which were diagnosed clinically atindustrial Accident Hospital affiliated with Catholic Medical Collage, suring the period of 3 years from 1974 to1976. 265 cases of silicosis consisted of 96 cases (35%) of coal miner, 91 cases (34%) of coal choicer and 82cases (31%) of others. The average age was 42.2 years and average working period was 9.2years. Qualitative andquantitative features in the analysis of roentgen findings were based on UICC/Cincinnati and KLO classification.The qualitative features showed 26% of "p" opacity, 46% of "q" opacity 4% of "r" opacity as rounded profusion and5% of "s" opacity, 11% of "t" opacity, 2% of "u" opacity as irregular profusion of small opacities.Large opacitiesshowed 3% of group A, 2% of group B and 1% of group C. Quantitative features revealed 25% of Type 1, 54% of Type2, 16% of Type 3 and 5% of Type 4. The qualitative and quantitative features showed significant differences as ageand working period increased with age and working period. Major complications were pulmonary emphysema,tuberculosis and pleural abnormalities.
Coal ; Miners ; Silicosis