No abstract available.
Leprosy*

No abstract available.
Carcinogenesis* ; Oenothera biennis*

PURPOSE: To evaluate the clinical effect of amniotic membrane (AM) graft and drainage valve implantation for the treatment of bullous keratopathy combined with intractable glaucoma. METHODS: Total 15 patients (15 eyes) were analyzed who underwent the operation for bullous keratopathy combined with intractable glaucoma, from Feb. 2002 to Aug. 2003. Under retrobulbar anesthesia, Ahmed valve was implanted under the supratemporal conjunctiva and exposed valve was covered with AM. And then, AM graft was performed after lamellar keratectomy for treatment of keratopathy. Serial check of IOP, corneal status and complications were performed after operation and during follow up. RESULTS: Mean IOP at last follow up was 11 mmHg. Corneal epithelium was stabilized within 10days. No serious complication was found and the drainage tube was well positioned. Especially, there is no pain in all cases. CONCLUSIONS: AM graft and valve implantation was clinically effective method for treatment of bullous keratopathy, combined with intractable glaucoma.
Amnion* ; Anesthesia ; Conjunctiva ; Drainage ; Epithelium, Corneal ; Follow-Up Studies ; Glaucoma* ; Humans ; Transplants*

PURPOSE: Mycobacterium tuberculosis usually affects the lungs, although it may involve various segments of the eye and cause severe visual loss if not treated properly. We report the case of Mycobacterium tuberculosis keratitis treated successfully with antituberculous medication and amniotic membrane transplantation. METHODS: A 48-year-old male patient diagnosed as cervical tuberculous lymphadenitis about 20 years ago was referred from other hospital. He complained about painless corneal opacity on right eye. And other systemic evaluation other than cervical lymphadenitis was not remarkable. On biomicrosopy, peripheral multiple corneal opacity and neovascularization were observed. Fortified tobramycin eyedrops and oral antituberculous medication were used preoperatively. Under local anesthesia, the lesion was removed, and lamellar keratoplasty with lyophilized cornea and amniotic membrane transplantation was performed. Amikacin eyedrops was used postoperatively. RESULTS: From postoperative day 15, corneal opacity was decreased gradually. CONCLUSIONS: Mycobacterium tuberculosis should be considered as one of the causes of keratitis manifesting painless corneal opacity concomitant with cervical tuberculous lymphadenitis. Proper examination and management are necessary.
Amikacin ; Amnion ; Anesthesia, Local ; Cornea ; Corneal Opacity ; Corneal Transplantation ; Humans ; Keratitis* ; Lung ; Lymphadenitis ; Male ; Middle Aged ; Mycobacterium tuberculosis* ; Mycobacterium* ; Ophthalmic Solutions ; Tobramycin ; Tuberculosis, Lymph Node

BACKGROUND AND OBJECTIVES: Herpes zoster(HZ) is a well known viral infection of the nervous system. HZ is associated with the neurologic complication. It may have been expected a change in the cerebrospinal fluid(CSF) of patients with HZ. The purpose of this paper is to present the correlation between CSF findings and neurologic complications in HZ. METHOD: The patients(n=75) with HZ were 31 male and 26 females, who were ranged in age from 15 to 79years(mean 53.4 years) admitted to department of Neurology of Chung Ang Gil General Hospital from June 1992 to May 1995. The patients were evaluated for the etiology, lesion distribution, and complications. CSF study was performed in 32 patients(male/female=20/12), whose age ranged from 16 to 79 years(means 51years) during 5 days to 10days after initial symptom onset. CSF findings were analyzed for their etiology, lesion distribution and complication. RESULTS: The CSF of 25 patients(78.1%) showed pleocytosis(5 to 49/mm3 in 10 patients, means, 62.1/mm3). 7 patients(12.3%) had meningitis symptoms, whose cell counts of CSF were more than 50/mm3(means 128.4/mm3) postherapeutic neuralgia was more common in elder patient than younger patients(p=0.005). Complications tended to correlate with the cell counts of CSF. There was no difference in CSF finding between cranial segmental involvements. CONCLUSION: We confirmed the pleocytosis in CSF of patients with HZ and suggest the development of complications in patients in patients with HZ tend to correlate with the cell counts of CSF.
Cell Count ; Female ; Herpes Zoster* ; Hospitals, General ; Humans ; Leukocytosis ; Male ; Meningitis ; Nervous System ; Neuralgia ; Neurology

BACKGROUND AND OBJECTIVES: Herpes zoster(HZ) is a well known viral infection of the nervous system. HZ is associated with the neurologic complication. It may have been expected a change in the cerebrospinal fluid(CSF) of patients with HZ. The purpose of this paper is to present the correlation between CSF findings and neurologic complications in HZ. METHOD: The patients(n=75) with HZ were 31 male and 26 females, who were ranged in age from 15 to 79years(mean 53.4 years) admitted to department of Neurology of Chung Ang Gil General Hospital from June 1992 to May 1995. The patients were evaluated for the etiology, lesion distribution, and complications. CSF study was performed in 32 patients(male/female=20/12), whose age ranged from 16 to 79 years(means 51years) during 5 days to 10days after initial symptom onset. CSF findings were analyzed for their etiology, lesion distribution and complication. RESULTS: The CSF of 25 patients(78.1%) showed pleocytosis(5 to 49/mm3 in 10 patients, means, 62.1/mm3). 7 patients(12.3%) had meningitis symptoms, whose cell counts of CSF were more than 50/mm3(means 128.4/mm3) postherapeutic neuralgia was more common in elder patient than younger patients(p=0.005). Complications tended to correlate with the cell counts of CSF. There was no difference in CSF finding between cranial segmental involvements. CONCLUSION: We confirmed the pleocytosis in CSF of patients with HZ and suggest the development of complications in patients in patients with HZ tend to correlate with the cell counts of CSF.
Cell Count ; Female ; Herpes Zoster* ; Hospitals, General ; Humans ; Leukocytosis ; Male ; Meningitis ; Nervous System ; Neuralgia ; Neurology

Ophthalmoplegic migraine is a syndrome characterized by the typical history of migrainous headache followed by ophthalmoplegia in the absence of demonstrable intracranial lesion. Until now, investigations of regional cerebral blood flow (CBF) in patient,; with migraine have been performed during prodromal and/or headache phases by brain SPECT with Tc-99m HMPAO. However, no such paper has described patients with ophthalmoplegic migraine. We present a 14-year-old girl with 4 episodes of paroxysmal migrainous headache on the right fronto-orbital area without aura followed by ptosis and diplopia, which were always gradually resolved without aberrant regeneration over 2 or 3 weeks period. Neurologic examination showed the right internal and external ophthalmoplegia. Diagnostic studies (including laboratory testis, Tensilon test, brain MRI, and cerebral angiography) were normal. Serial brain SPECT studies with Tc-99m HMPAO showed the presence of reversible ischemia in the branches of the posterior cerebral artery.
Adolescent ; Brain* ; Diplopia ; Edrophonium ; Epilepsy ; Female ; Headache ; Humans ; Ischemia* ; Magnetic Resonance Imaging ; Migraine Disorders ; Neurologic Examination ; Ophthalmoplegia ; Ophthalmoplegic Migraine* ; Posterior Cerebral Artery ; Regeneration ; Technetium Tc 99m Exametazime ; Testis ; Tomography, Emission-Computed, Single-Photon*

No abstract available.
Aneurysm, False*

PURPOSE: Ultraviolet rays, dust, and the human papilloma virus are well known as extrinsic risk factors in pterygium pathogenesis, but the intrinsic factors and nasal predominance related to the development of pterygium have not been fully ulucidated. Herein, we sought to determine whether the relative ischemic state of nasal bulbar conjunctiva affects the development of nasal predominance in pterygium pathogenesis. METHODS: Anterior segment fluorescein angiography was performed and the anterior bulbar conjunctival temperature was obtained to identify the presence of nasal ischemia. Tear samples were collected from both a normal and a patient group. The difference in SDF-1 (stromal cell-derived factor-1) was determined through ELISA and Western blot anyalyses. The excised pterygium tissues were immunohistochemically stained by antibodies for HIF-1 (hypoxia-inducible factor-1), SDF-1, and CXCR4. RESULTS: Results of the anterior segment fluorescein angiography showed that, the vascularity of the nasal limbus was lowest among each groups and the nasal filling time was significantly delayed in the patient group. The temperature of the nasal bulbar conjunctiva was lower than that of the temporal bulbar conjunctiva. The concentration of SDF-1 in tears was significantly higher in the patient group. In the immunohistochemical stain, HIF-1, SDF-1, and CXCR4 were revealed at epithelial basal cells or vascular endothelia in the stroma and the stained areas corresponded to each other. CONCLUSIONS: From the above results, we assumed that low nasal vascularity and temperature resulted in relative ischemic state and this hypoxic injury may be a major risk factor in pterygium development through the mobilization of endothelial progenitor cells by HIF-1 induced SDF-1 overexpression.
Antibodies ; Blotting, Western ; Conjunctiva ; Dust ; Enzyme-Linked Immunosorbent Assay ; Fluorescein Angiography ; Humans ; Intrinsic Factor ; Ischemia ; Papilloma ; Pterygium* ; Risk Factors ; Stem Cells ; Ultraviolet Rays

We report one case of renal vein thrombosis that was mimicking symptoms for urinary caculi.
Renal Veins* ; Thrombosis*