A case of Peutz-Jeghers syndrome was experienced with melanin pigmentation in the oral cavity and lips associated small intestine polyposis. Diagnosis of Peutz-Jeghers syndrome was established by clinical characteristics of skin and X-ray studies of gastrointestinal tracts.
Diagnosis ; Gastrointestinal Tract ; Intestine, Small ; Lip ; Melanins ; Mouth ; Peutz-Jeghers Syndrome* ; Pigmentation ; Skin

A fistulous comunication between kidney and colon after trauma is rare and usually causes severe damage to kidney necessitating nephrectomy. Intrarenal aneruysm after trauma is also rare and its accurate diagnosis is important. Authors have experienced a reno-colic fistula and intrarenal aneruysm occured in a same patient afterpenetrating renal injury.
Aneurysm ; Colon ; Diagnosis ; Fistula ; Humans ; Kidney ; Nephrectomy

No abstract available.
Enterocolitis, Necrotizing*

The Pumping technique generally has been known as a diagnostic method that predicts intracapsular status and selects required evaluation and treatment. But, in addition to this indication, when it is followed by Lavage and Manipulation technique, this may be used as therapeutic method that is effective on Closed Lock with limited mouth opening and pain. Therefore, we examined results of this technique abut Closed Lock and would like to report therapeutic effects of Lavage and Manipulation technique. We selected 40 patients of 200 patients diagnosed as Closed Lock over 53 months from SEP. 1991 to PEB. 1996, who were possible follow-up and performed by Lavage and Manipulation technique. Appraisal between pre-procedure and post-procedure was performed just after procedure, in 1 month and in 3 months, and therapeutic effects were divided by marked, useful, a little useful and ineffective. As a result, Lavage and Manipulation technique had remarkable increase of maximum mouth opening(>5mm) in 39 persons(98%) just after proceure, 36 persons(90%) in 1 month, and 39 persons(98%) in 3 months, and subsided pain completely just after procedure and had remarkable decrease of pain in 30 persons(75%) in 1 month, 32 persons(80%) in 3 months. So we concluded that the Lavage and Manipulation technique is effective therapy of Closed Lock which can be used with ease.
Follow-Up Studies ; Humans ; Mouth ; Temporomandibular Joint* ; Therapeutic Irrigation*

The authors report the experience of twenty patients of transpedicular Zielke instrumentation after anatomical reduction of the spondylolisthesis. Anstomical reduction was done with the aid of temporary application of Harrington distraction rod, and the reduced segment was fixed with transpedicular Zielke instrumentation. And, anterior interbody fusion was supplemented in a single stage operation. Follow up period was between 13 to 25 months after operation with the average of 19 months. 1. The age of the patients was 38 years in average ranging from 11 to 61 years. 2. Types of the spondylolisthesis were spondylolytic type in 11 cases, degenerative type in 6 cases, dysplastic type in 1 case and pathologic type in 2 cases. 3. The level of the lesion were L5-Sl in 12 cases, L4-5 in 7 cases and L3-4 in 1 case. 4. Pre-operative clinical feature included low back pain in 95%, radiating pain in 65%, and neurological claudication in 45%. 5. The average percentage of slippage was changed from 24% preoperatively to 6% postoperatively and to 8% at the final follow up. The initial correction rate was 75% and the amount of correction loss during the follow up period was 11% in average. 6. Slip angle was changed from 3°preoperatively to −3°poetoperatively and to 0°at the end of follow up. In the 12 cases with local kyphosis, average slip angle of 14°preoperatively was improved to 2°postoperatively, and to 7°at the end of follow up. 7. Bony fusion was obtained in 19 cases within 4 to 6 months. 8. There were 2 cases of metal failure with considerable loss of reduction ; one patient with pathologic spondylolisthesie due to active tuberculous spondylitis required re-operation and another patient showed fusion eventually in the redisplaced position. Other complication included 1 transient dysuria, 1 ileus and 2 meralgia paresthetics. 9. Clinical symptoms were improved in 95%. Follow up result of the operation according to Gill's criteria were excellent 65%, good 25%, fair 5%, and poor 5%.
Dysuria ; Follow-Up Studies ; Humans ; Ileus ; Kyphosis ; Low Back Pain ; Spondylitis ; Spondylolisthesis

No abstract available.
Stomach Neoplasms*

PURPOSE: To evaluate the effect of orbital decompression surgery on quality of life in thyroid-associated ophthalmopathy (TAO) patients. METHODS: From August 2014 to December 2015, 80 patients diagnosed with TAO at our clinic were retrospectively analyzed. The patients were divided into 2 groups: 30 patients who underwent orbital decompression surgery and 50 patients who did not receive surgery. The Korean version of the Grave's ophthalmopathy specific quality of life (GO-QoL) questionnaire was completed by all patients. We compared questionnaire scores between groups and analyzed demographic and clinical factors affecting change in GO-QoL. RESULTS: The patients who underwent orbital decompression had lower mean GO-QoL score for appearance in comparison with patients without orbital decompression (p < 0.001). The mean GO-QoL score for appearance was increased from 28.8 ± 17.1 to 51.5 ± 18.8 after orbital decompression (p = 0.024). The mean GO-QoL score for visual function was not different between the patients who did not receive surgery and the orbital decompression group. The mean GO-QoL score for visual function was not changed after orbital decompression. There was a significant relation between postoperative proptosis degree and change in GO-QoL score for appearance after orbital decompression. CONCLUSIONS: GO-QoL score for appearance was significantly improved after orbital decompression surgery, and psychological interventions should be considered to enhance the quality of life outcomes.
Decompression* ; Exophthalmos ; Graves Ophthalmopathy* ; Humans ; Orbit* ; Quality of Life* ; Retrospective Studies ; Troleandomycin

The ocular manifestations of leukemic retinopathy can be divided into secondary manifestations due to hemorrhage and macular edema, and direct manifestations of leukemic infiltration. Case reports about leukemic infiltration of the optic nerve head are rare. We have experienced a case of leukemic retinopathy in a 16-year-old girl. She visited to our hospital due to sudden decrease of visual acutiy on both eyes and confirmed acute lymphocytic leukemia on bone marrow biopsy. In addition to macular edema and hemorrhage due to secondary manifestations of leukocytosis, there were sheathing noted about retinal arterioles, and disc edema were present on both eyes which seems to be the optic nerve head infiltration of leukemic cells.
Adolescent ; Arterioles ; Biopsy ; Bone Marrow ; Edema ; Female ; Hemorrhage ; Humans ; Leukemic Infiltration* ; Leukocytosis ; Macular Edema ; Optic Disk* ; Optic Nerve* ; Precursor Cell Lymphoblastic Leukemia-Lymphoma ; Retinaldehyde

No abstract available.
Mitral Valve Insufficiency*

BACKGROUND: CpG islands' methylation of p15 promoter region is associated with inactivation of the p15 gene, which negatively regulates the cell cycle. We investigated the prevalence and prog-nostic significance of p15 gene methylation in AML and ALL patients, and sequentially analyzed p15 methylation during the follow-up. METHODS: This study included 52 and 25 bone marrow aspirates from 33 AML and 22 ALL patients, respectively; p15 methylation was analyzed by methylation specific PCR. RESULTS: The methylation of the p15 gene was observed in 57% of newly diagnosed AML, 70% of relapsed AML, and 23% of newly diagnosed ALL patients. Moreover, p15 methylation was found in 65% of AML and 33% of ALL patients with a normal karyotype. No association was found between p15 methylation status and prognostic factors or clinical outcomes; however, p15 methylation status correlated well with the clinical and pathologic features of disease status during the follow-up. CONCLUSIONS: The methylation of the p15 gene may be of use as a marker for disease monitoring of acute myelogeneous leukemia, especially in patients with a normal karyotype, although p15 methy-lation doesn't seem to be associated with prognosis.
Bone Marrow ; Cell Cycle ; Follow-Up Studies ; Humans ; Karyotype ; Leukemia* ; Methylation* ; Polymerase Chain Reaction ; Prevalence* ; Prognosis ; Promoter Regions, Genetic