Objective: To investigate the clinical diagnosis value of serum precalcitonin(PCT) and early predictive significance of prealbumin (PA) and retinol-binding protein (RBP) in liver and renal injury for sepsis in children. Methods: One hundred and fifty sepsis children were enrolled from the ward of children in Taizhou Hospital of Zhejiang Province from January 2018 to August 2019. In the same period 150 children with common infection and 150 healthy children who underwent physical examination were included into the study. According to the test, basic data was collected, and biochemical examinations, including the concentrations of the liver function, renal function, PA and RBP were measured. Then the data in the three groups was analyzed. Results: The levels of PCT in sepsis group were significantly higher than those in the common infection group and the normal group: (7.02 ± 5.26) μg/L vs. (0.37 ± 0.28), (0.03 ± 0.01) μg/L; the levels of PA and RBP in sepsis group were significantly lower than those of the other two groups: (9.31 ± 4.36) mg/dl vs. (31.05 ± 5.05), (33.56 ± 4.59) mg/dl; (9.26 ± 3.58) mg/L vs. (31.2 ± 5.89), (33.83 ± 6.31) mg/L, and there were significant statistical differences (P < 0.05). The levels of PA and RBP in the common infection group and the normal group were normal and there was no difference between the two groups (P > 0.05). There were no significant statistical differences in other indicators such as alanine aminotransferase, asparagus cochinchinensis, albumin, urea nitrogen and creatinine (P > 0.05). Conclusions Combined detection of serum PCT, PA and RBP plays an important role in the early diagnosis of children′s sepsis.

Objective: To investigate the safety and efficacy of pingyangmycin (bleomycin A5) sclerotherapy for early peripheral arteriovenous malformations (AVM). Methods: Thirteen cases of early-stage [Schobinger clinical stage (Ⅰ/Ⅱ)] peripheral AVM patients (11 stage Ⅰ and 2 stage Ⅱ patients) aged between 3 months and 51 years were selected between January 2012 and May 2015. Pingyangmycin sclerotherapy injections were administered with B-scan ultrasonography or digital subtraction angiography positioning. All patients underwent relevant supplementary examinations before and after the procedure, and clinical evaluation was performed based on the improvement of the clinical symptoms of the patient and re-examination of lesion by imaging. Results: A total of 88 injections were administered to the 13 patients with an average of 6.7 injections per patient, 3-6 years of follow-up. Based on clinical evaluation, 7 patients were generally cured, 3 patients had significant improvement, 2 patients had partial improvement, and 1 patient had no improvement. Seven patients had different levels of postoperative swelling that resolved on its own. No serious complications occurred. Conclusions Pingyangmycin sclerotherapy for treatment of early peripheral AVM was effective and had few complications. It can control further progression of pathological changes.