1.Advances in UL7 gene of herpesvirus.
Jie HUANG ; An-Chun CHENG ; Ming-Shu WANG
Chinese Journal of Virology 2011;27(5):501-504
Animals
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Herpesviridae
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genetics
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metabolism
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Humans
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Viral Proteins
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chemistry
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genetics
;
metabolism
3.Effect of Valproate on Leptin and Serum Lipids in Children with Epilepsy
zhao-chun, WEN ; ru-ming, WANG
Journal of Applied Clinical Pediatrics 2004;0(12):-
Objective To explore the effect of valproate(VPA) on body mass index(BMI),leptin and serum lipids in children with epilepsy.Methods (Twenty-)four cases with epilepsy were selected.BMI and serum levels of leptin,total cholesterol(TC),(triacylgly)-cerol(TG),high density lipoprotein-cholesterin(HDL-C),low density hipoprotein-cholesterin(LDL-C) after treated with VPA for 3 months and 6 months were determined.Results The levels of BMI,leptin,TC,TG,LDL-C after treated 3 months were all significantly higher than those of initial(all P0.05).Those in treated 6 months were same as levels of treated 3 months.Only LDL-C level was lower than that of 3 months and same as level of before treatment.Conclusion VPA do have efficacy to cause obesity in children with epilepsy,and most of the cases occur in the first 3 months after VPA treatment.
4.Role and tasks of teachers in PBL
Chun-ming JIANG ; Zhu-ying WANG
Chinese Journal of Medical Education Research 2011;10(11):1348-1350
PBL tutoring is quite different from the traditional tutoring and emphasizes the importance of student-centred instead of teacher-centred education.In PBL,teachers guide students to find answers to their own questions and facilitate students' learning process.Therefore,the tutor role is complex and has a fundamental change.
5.Early diagnostic and prognostic value of procalcitonin in critical ill patients with sepsis
Ming-Gang WANG ; Chun-Sheng LI ; Jun YANG ; Shuo WANG ;
Chinese Journal of General Practitioners 2003;0(04):-
Objective To investigate the diagnostic value of procalcitonin(PCT)as an early indicator for sepsis.Methods Serum levels of PCT and C-creative protein(CRP)and white blood cell (WBC)count were measured in 30 patients in critical condition hospitalized at an intensive care unit(ICU) with diagnosis of systemic inflammatory response syndrome(SIRS).They were divided into two groups, sepsis and non-sepsis,based on their clinical manifestations and results of lab tests.Blood specimen was collected from each patient for measurement of PCT,CRP and WBC count on the 1~(st),3~(rd)and 7~(th)day after hospitalization and bacteriological culture for blood and sputum,and chest X-ray was performed,as well. Acute physiology,age and chronic health evaluation(APACHE Ⅱ)was made on the 1~(st),3~(rd)and 7~(th)day after hospitalization to assess their ill condition.Their prognosis were judged on the 28~(th)day of the follow-up. Results Serum level of PCT increased significantly in the sepsis group(with the highest of 10.13 ng/ml), as compared with that in the non-sepsis group.Sensitivity,specificity and predictive value of a positive test for a cut-off value of serum level of PCT at 0.5 ng/ml were 97.0%,91.7% and 82.1%,respectively, which were all better than those of serum level of CRP and WBC count.Serum level of PCT in the patients was significantly associated with their prognosis,and PCT in those died was significantly higher than that in those survived.Whereas,serum level of CRP and WBC count elevated in both groups,but the difference between the two groups did not reach a level of statistical significance.Conclusion Serum level of PCT can be used as an early indicator for judgment of sepsis for a patient with infection and reflection of severity of illness.
6.Study of gene expression of heat shock protein70 induced by lead.
Jing ZHANG ; Ke-Ming LIU ; Chun-Hua WANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2008;26(12):752-754
Animals
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Cells, Cultured
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Female
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HSP70 Heat-Shock Proteins
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genetics
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metabolism
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Humans
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Lead
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pharmacokinetics
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toxicity
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Liver
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metabolism
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Male
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RNA, Messenger
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genetics
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Rats
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Rats, Wistar
9.Cluster analysis of variables in liver syndrome of TCM.
Shi-jun ZHANG ; Ming-xiu SHEN ; Xian-chun WANG
Chinese Journal of Integrated Traditional and Western Medicine 2004;24(1):75-76
Adolescent
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Adult
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Aged
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Aged, 80 and over
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Cluster Analysis
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Diagnosis, Differential
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Female
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Humans
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Liver Diseases
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classification
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epidemiology
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Male
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Medicine, Chinese Traditional
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Middle Aged
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Yang Deficiency
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classification
;
epidemiology
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Yin Deficiency
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classification
;
epidemiology