Blood Glucose ; metabolism ; Female ; Glycogen Storage Disease ; diagnosis ; Humans ; Infant, Newborn ; Liver ; pathology

No abstract available.
Alopecia*

Objective To explore clinical characteristics of severe pre-eclampsia and eclampsia complicated with reversible posterior leukoencephalopathy syndrome(RPLS).Methods Clinical data of 31 cases of severe pre-eclampsia and eclampsia complicated with RPLS were studied retrospectively.ResulIs These 31 cases with RPLS accounted for 48% of those with eclampsia,.and all presented with hypertension,headache and disturbalice of vision,24 cases with seizure episodes,19 cases with nausea and vomiting and 13 with continuous dysphoria after seizure.Neuroradiologic findings showed edema predominantly in the bilateral posterior cerebral white matter,especially in occipital-parietal lobe,with low density lesions in CT and long T1 and T2 signals in brain MRI. Conclusions Severe pre-eclampsia and eclampsia tended to complicate with RPLS,presenting severe hypertension,headache,disturbance of vision and recurrent seizure as major clinical manifestations.

No abstract available.
Olecranon Process* ; Ulna*

Objective To explore the treatment of hemangioma associated with thrombopenia(Kasabach-Merritte syndrome,KMS) in infant.Methods The clinical manifestation and the therapy of 14 cases patients with KMS in hospital from 2003 to 2006 were collected ang analyzed,the 400 g/L urea(manufactured by ourself)combined with methylprednisolone local injection were used and followed 0.5 to 1.0 year.Results Two in 14 cases were emergency exairesis,7 cases were recurred for several times,12 cases were cured,1 case was improved,1 case was loss the connection.Conclusions It is an ideal therapy method to use the urea combined with glucocorticoid to treat infancy KMS,little trauma,definite effective,low side effect,high cure rate.

Objective: To explore the effects of Polygonatum odoratum on body based on metabonomics. Methods: The ultra performance liquid chromatography coupled with mass spectrometry (UPLC-MS) and principle component analysis(PCA) and orthogonal partial least squares discriminant analysis(OPLS-DA) were used to evaluate the changes of endogenous substances in rats after intragastric administration of Polygonatum odoratum. Results: Significant differences between the control group and administration group were observed in PCA and OPLS-DA model. Five potential biomarkers between control group and administration group were identified. The relative content of Alpha-Tocotrienol, PC(14:1(9Z)/14:1(9Z)), Stearic acid, Theasapogenol A, Docosahexaenoic acid increased. Conclusion: The biomarkers had many beneficial activities, so the Mongolian medicine Polygonatum odoratum had the function of health care. Key words: Mongolian drug; Polygonatum odoratum; Biomarkers; UPLC-MS

No abstract available.
Animals ; Humans ; Infant, Newborn* ; Intestines* ; Rats*

OBJECTIVES: To investigate the correlation of the initial Computerized Tomography(CT) findings of the brain and the functional outcome, and to suggest the initial CT findings as a functional outcome predictor in the traumatic brain injured(TBI) patients. METHODS: Thirty-nine TBI patients were included in this study. Subjects were divided into groups of non-focal or focal TBI, and with or without a depressed skull fracture according to their initial brain CT findings. RESULTS: The non-focal TBI patients were not significantly different from focal TBI patients in the days from onset to rehabilitation, rehabilitation stay, and initial FIM score. However their outcome in FIM gain and FIM efficiency significantly worse than focal TBI patients. The TBI patients with a depressed skull fracture were not significantly different from the patients without a depressed skull fracture in the days from onset to rehabilitation, rehabilitation stay, and intial FIM score. However their outcomes were significantly worse than patients without a depressed skull fractrue in FIM efficiency. CONCLUSION: The initial brain CT findings were generally useful for the prediction of functional outcomes in TBI patients.
Brain Injuries ; Brain* ; Humans ; Rehabilitation ; Skull ; Skull Fracture, Depressed

BACKGROUND: Alopecia areata, especially when severe, often profoundly affect the lives of those afflicted. Unfortunately, the clinical features and therapeutic results of alopecia areata are variable and unpredictable. OBJECTIVE: The authors performed a study on alopecia areata in order to evaluate the clinical manifestations and the effects of treatment with intralesional injections of triamcinolone acetonide suspension, immunotherapy with diphenylcyclopropenone(DPCP) and combination therapy of intralesional injections of triamcinolone acetonide suspension and immunotherapy with DPCP. METHODS: A clinical study of 357 patients with alopecia areata was performed fram March l994 to February l996 at the Department of Dermatology, Yongsan Hospital, College of Medicine, Chung- Ang University. RESULTS: 1) The age distribution showed a peak incidence in the third decade(36.1%) and the average age was 27.6 years. 2) The most common site of predilection was the occipiital region in both male and female, which were 127 cases(73.0%), 89 cases(64.5%) respectively. 3) The relapse rate was 26.1%. 4) The farnily histories were significant in 37 cases(10.4%). 5) Associated diseases with alopecia areata were seborrheic dermatitis, atopic dermatitis, hepatitis, diabetes mellitus, urticaria, allergic dermatitis, etc in 117 cases(32.8%). 6) The therapeutic effect in cases of bald areas treated with intralesional injections of triamcinolone acetonide, immunotherapy with DPCP and combination therapy revealed no difference based on increases in the size and number of bald areas. CONCLUSION: These findings suggest that alopecia areata prominently develops in the third decade, when the severity of alopecia areata increases and the therapeutic effect decrenses. There was no difference in the therapeutic effect on the size & number of balded areas.
Age Distribution ; Alopecia Areata* ; Alopecia* ; Dermatitis ; Dermatitis, Atopic ; Dermatitis, Seborrheic ; Dermatology ; Diabetes Mellitus ; Female ; Hepatitis ; Humans ; Immunotherapy ; Incidence ; Injections, Intralesional ; Male ; Recurrence ; Triamcinolone Acetonide ; Urticaria

BACKGROUND: Female diffuse hair loss is a common baldness with a multifactorial origin. In recent studies, it has been suggested that reduced or depleted iron stores are a cause of female diffuse hair loss. OBJECTIVE: We performed this study in order to elucidate the pathogenesis of female diffuse hair loss and to evaluate the differences in serurn iron levels between normal females and those with diffuse hair loss in Korea. METHODS: Blood levels of hemoglobin, iron, TIBC, ferritin, testosterone, thyroid function, ANA and Zn were examined in 30 patients with female diffuse hair loss and 20 normal females. RESULTS: 1) Serum Zn, testosterone, T4, TSH of the patient group were not statistically significant compared to those of the control group (p>0.05). 2) TIBC values were significantly increased, but serum ferritin levels were signifieantly decreased in the patient group (p<0.05). There were no significant differences in hemoglobin, serum iron in both groups (p>0.05). 3) No significant differences between clinical severity and the values of serum Zn, testosterone, T4, TSH, TIBC, serum femtin, hemoglobin and serum iron were observed (p>0.05). CONCLUSION: These findings suggested that the variations of TIBC, serum femtin levels may play a role in the pathogenesis of female diffuse hair loss, but further studies will be needed for evaluation of this condition.
Alopecia ; Female* ; Ferritins ; Hair* ; Humans ; Iron* ; Korea ; Testosterone ; Thyroid Gland