1.Analysis of pneumoconiosis death cases in Yunnan province between 1950 and 2000.
Chun-mi LAI ; Yun GAO ; Ming-lin YANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2008;26(4):227-229
Adult
;
Aged
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Cause of Death
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China
;
epidemiology
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Female
;
Humans
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Male
;
Middle Aged
;
Pneumoconiosis
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mortality
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Retrospective Studies
;
Young Adult
2.Study on the health standard for phosphorus pentasulfide in the workshop air.
Chun-Mi LAI ; Shu-Bo LIU ; Shun TAO ; Jian-Yun DAI ; Yun GAO ; Wei-Jun LI ; Shu-Qiao CAO
Chinese Journal of Industrial Hygiene and Occupational Diseases 2004;22(4):310-311
Adult
;
Air Pollutants, Occupational
;
adverse effects
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Chemical Industry
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Female
;
Humans
;
Insecticides
;
adverse effects
;
Male
;
Maximum Allowable Concentration
;
Middle Aged
;
Occupational Diseases
;
chemically induced
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diagnosis
;
Organothiophosphorus Compounds
;
adverse effects
;
Phosphorus Compounds
;
adverse effects
;
Sulfides
;
adverse effects
3.The Awareness,Treatment and Control of Hypertension and Its Determinants in the Elderly Hypertensive Patients of Dean Nationality:A Multilevel Model Analysis
Cheng-Huan SUN ; Jia ZHOU ; Yong MAO ; Jia-Hong LUO ; Tian-Shu CHU ; Chun-Mi LAI ; Bing-Xian QI ; Qian ZHANG
Journal of Kunming Medical University 2018;39(1):39-44
Objective To determine the awareness, treatment and control of hypertension and its determinants in the elderly hypertensive patients of Dean nationality so as to explore the associated determinants. Methods This was a cross-sectional, population-based survey. A total of 939 persons aged 60 years and older sampled by stratified sampling method from the elderly population of Dean nationality were examined from July to September 2016. Meanwhile, the data of medical history and examination were collected. Results There were 353 elderly patients with hypertension in the 939 subjects. The awareness, treatment and control of hypertension in the elderly hypertensive patients (EHP), which was 47.3%, 36.5%and 22.1%respectively, were higher than the results of previous national study and had the upward trends with the increasing age (<0.05) . In comparison with the reference group, EHP living in middle economic level area had the higher awareness, treatment and control of hypertension (<0.05) . The results of covariate-adjusted multilevel logistic regression model indicated that there was a cross-level interaction effect between middle economic level area and dyslipidemia on the awareness and treatment of hypertension respectively, and a cross-level interaction effect between middle economic level area and low fat diet on the control of hypertension ( <0.05) . The individual level covariates, age (OR=1.3412, 1.3144, 95% CI 1.0217-1.7609, 1.0030-1.7225) and diabetes ( OR=2.6735, 2.3078, 95% CI 1.0721-6.6672, 1.0240-5.2007), had the positive association with the awareness and treatment of hypertension;age (OR=1.4740, 95%CI 1.0034-2.1654), non-drinking (OR=3.2056, 95%CI 1.5554-6.6066) and low salt diet (OR=3.6969, 95%CI 1.7996-7.5946) had the positive association with the control of hypertension. Conclusion The awareness, treatment and control of hypertension in the EHP of Dean nationality were higher than those of the national level, and the dominant factors were economic level, age, dyslipidemia, diabetes, non-drinking, low fat diet and low salt diet, etc.
4.Synergistic Mechanism of Interferon alpha-1b, Interleukin-2 and Thalidomide for Immune Regulation in Patients with Acute Myeloid Leukemia.
Rui-Hua MI ; Lin CHEN ; Ya-Lan ZHOU ; Dong-Bei LI ; Sha LIU ; Xiao-Jiao WANG ; Jia LIU ; Min-Fang WANG ; Xiao-Miao MA ; Zhi-Chun LI ; Hong-Mian ZHAO ; Yu-Lin XU ; Shu-Xia CHEN ; Hai-Ping YANG ; Zhi-Qiang GUO ; Chun-Lai LUAN ; Shu-Li GUO ; Qing-Lin SONG ; Xu-Dong WEI
Journal of Experimental Hematology 2021;29(1):26-31
OBJECTIVE:
To explore the synergistic immunomodulatory mechanism of interferon alpha-1b, interleukin-2 and thalidomide (ITI) regimen on patients with acute myeloid leukemia (AML).
METHODS:
Sixty eight untreated de novo or relapsed or refractory or maintenance therapy patients with AML admitted in the Affiliated Cancer Hospital of Zhengzhou University and the other 11 medical units from March 2016 to May 2019 were treated with ITI regimen. Peripheral blood specimen per patient was collected into EDTA-K3 anticoagulation vacuum tube before the administration of ITI and 3 months after the treatment; peripheral blood lymphocyte subsets and perforin and Granzyme B expression were analyzed by using flow cytometry; the levels of VEGF, IFN-γ, TNF-α and IL-6 in the plasma were detected by using a cytometric bead array. Thirty-five healthy subjects from the hospital physical examination centre were selected as normal controls.
RESULTS:
The ratio of CD4
CONCLUSION
The ITI regimen can raise the ratio of CD4
CD8-Positive T-Lymphocytes
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Humans
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Interferon-alpha
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Interleukin-2
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Leukemia, Myeloid, Acute/drug therapy*
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Perforin
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Thalidomide