1.Sebaceous Hyperplasia Treated with Isotretinoin.
Won Hyoung KANG ; Dong Hoon SONG ; Soo Il CHUN
Korean Journal of Dermatology 1986;24(1):133-135
We present herein a case of sebaceous hyperplasia in a 55-year-old male, who showed multiple asymptomatic yellowish papules on the forehead and the cheeks. Histopathologic examination of a papule revealed numerous sebaceous lobules grouped around several enlarged sebaceous ducts. Three weeks of oral administration. of isotretinoin 40 mg per day brought marked improvement.
Administration, Oral
;
Cheek
;
Forehead
;
Humans
;
Hyperplasia*
;
Isotretinoin*
;
Male
;
Middle Aged
2.Spotted Grouped Pigmented Nevi.
Soo Il CHUN ; Dong Hoon SONG ; Won Hyoung KANG
Korean Journal of Dermatology 1986;24(4):554-558
We experienced three cases of non-giant congenital nevus. They showed zosteriform or heart-shaped grouping of pigmented papules which were pierced by hairs. Histopathologic examination disclosed nevus cell infiltration in and around hair follicles and in the upper two thirds of reticular dermis. We would like to report these cases as follicle-centered spotted grouped pigmented nevi.
Dermis
;
Hair
;
Hair Follicle
;
Nevus
;
Nevus, Pigmented*
3.Matrix metalloproteinase-3 inhibitor I accelerates the early-stage repair of full-thickness articular cartilage defects in the knee of rats
Fu DONG ; Jinqi SONG ; Nan JIANG ; Chun LU
Chinese Journal of Tissue Engineering Research 2016;20(15):2156-2162
BACKGROUND:The biomechanical properties of naturaly regenerated damaged articular cartilage that belongs to the fibrovascular tissue are far worse than those of the normal cartilage so that they cannot meet the requirements for joint function, leading to traumatic arthritis and loss of joint function.
OBJECTIVE:To evaluate the effects of matrix metaloproteinase-3 (MMP-3) inhibitor I with different concentrations on the early-stage repair of ful-thickness articular cartilage defects in the knee of rats.
METHODS: Twenty-four Sprague Dawley rats were randomized into control, defect (DEF), and defect combined with low-(D+L) and high-dose inhibitor (D+H) groups (n=6 for each group), respectively. Full-thickness articular cartilage defects followed by intraarticular injection of low- and high-dose MMP-3 inhibitor I for 4 weeks was administered in the later two groups. Serum MMP-3 was detected using ELISA method before and after experiment, respectively. Femoral trochleas were collected to observe characteristics of repaired tissue by gross appearance scoring and O’Driscoll histological scoring with Safranine O-Fast Green staining, and to measure type II colagen by immunohistochemistry after experiment.
RESULTS AND CONCLUSION:Rats in the D+H group had obvious repair similarly to hyaline articular cartilage, while creamy white cartilage tissue and fibrous tissue repair were observed in D+L group and in DEF group. D+H group obtained the best repair results according to gross appearance scoring and O’Driscol histological scoring and the highest content of type II colagen (P< 0.05). MMP-3 concentration and the difference value before and after experiment were gradualy decreased in DEF, D+L, D+H, and control groups in sequence(P< 0.05). These findings demonstrate that MMP-3 inhibitor I accelerates the early-stage repair of ful-thickness articular cartilage defects in the knee of rats.
4.Clinical application of therapeutic plasma exchange.
Dong Seok JEON ; Bok Cheol HWANG ; Hyo Jin CHUN ; Jay Ryong KIM ; Dal Hyo SONG
Korean Journal of Blood Transfusion 1991;2(2):175-181
No abstract available.
Plasma Exchange*
;
Plasma*
5.The clinical observations in childhood asthma.
Kih Yeon SONG ; Yong Hyoun PARK ; Jin Gon JUN ; Young Hwan LEE ; Chun Dong KIM
Yeungnam University Journal of Medicine 1992;9(2):239-247
A clinical analysis was done on 134 cases with bronchial asthma who were admitted to the Department of Pediatrics Yeungnam University from May 1987 to October 1991. The results were as follows: 1) The peak age of bronchial asthma was under 2 years. The sex ratio of male to female was 2.9:1. 2) The outbreak of bronchial asthma was most common in fall, especially in September. 3) The past history of other allergic diseases were present in 22.4% of patients (30/134 cases), and the previous bronchiolitis in infancy were experienced in 12.7% of patients (17/134 cases). 4) According to the skin test for allergens done by RAST, the most common allergens were Mites and House dust. 5) Eosinophilia (T.E.C>250/min) was found in 29.1%t of patients, and elevated lgE level (>200 IU/ml) was found in 63.2% of patients. 6) No significant differences in the serum lgE level were found between male and female patients. No significant differences in the serum lgE level were found between asthma patients with and without other allergic diseases. 7) The serum lgE level of school aged patients was significant higher than that of preschool aged (p<0.01).
Allergens
;
Asthma*
;
Bronchiolitis
;
Dust
;
Eosinophilia
;
Female
;
Humans
;
Male
;
Mites
;
Pediatrics
;
Sex Ratio
;
Skin Tests
6.Analysis of blood transfused for past five years at Dongsan hospital.
Soo Jin PARK ; Dong Seok JEON ; Hyo Jin CHUN ; Jae Ryong KIM ; Dal Hyo SONG
Korean Journal of Blood Transfusion 1993;4(2):181-186
No abstract available.
7.Analysis of blood transfused for past five years at Dongsan hospital.
Soo Jin PARK ; Dong Seok JEON ; Hyo Jin CHUN ; Jae Ryong KIM ; Dal Hyo SONG
Korean Journal of Blood Transfusion 1993;4(2):181-186
No abstract available.
8.Changes of fibrinogen and coagulation factor NIII in cryoprecipitate according to storage temperature and time after thawing.
Young Jae KIM ; Hyo Jin CHUN ; Dong Seok JEON ; Jae Pyong KIM ; Dal Hyo SONG
Korean Journal of Clinical Pathology 1992;12(3):395-400
No abstract available.
Blood Coagulation Factors*
;
Fibrinogen*
9.Changes of fibrinogen and coagulation factor NIII in cryoprecipitate according to storage temperature and time after thawing.
Young Jae KIM ; Hyo Jin CHUN ; Dong Seok JEON ; Jae Pyong KIM ; Dal Hyo SONG
Korean Journal of Clinical Pathology 1992;12(3):395-400
No abstract available.
Blood Coagulation Factors*
;
Fibrinogen*
10.Review on Original Background of Multi-component Chinese Medicine and Its Future Expectation
Limei LIU ; Junhua ZHANG ; Guangxin YUE ; Dong BAI ; Zhenli LIU ; Chun WANG ; Ruihai WANG ; Zhiqian SONG
Chinese Journal of Information on Traditional Chinese Medicine 2016;23(5):1-4,5
“Multi-component Chinese medicine” (MCC Medicine) is a new TCM concept in recent ten years. It is a new formed TCM product accepted and approved by the new mode (component compatibility of medicines) for TCM research and development, which originated from TCM research and development and TCM pharmaceutics. MCC Medicine contains massive historical accumulation of TCM and distinctive characteristics of the times, which is closely connected with the TCM theory, current trend of the TCM development, clinical treatment requirements, and the development of modern science and technology. In order to promote the development of MCC Medicine, this article reviewed its original background and future trend, with a purpose to make clear the direction for the development of MCC Medicine.