1.Changes of TNF-alpha and C(3) complements in patients with silicosis.
Li-yan TIAN ; Jun JI ; Chun-xia YANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2007;25(9):572-572
Aged
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Aged, 80 and over
;
Complement C3
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metabolism
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Humans
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Immunoglobulin A
;
blood
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Male
;
Silicosis
;
blood
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Tumor Necrosis Factor-alpha
;
blood
2.Levels of interleukin-23 in asthmatic children before and after glucocorticosteroid treatment.
Yan-chun LI ; Ji-rong LU ; Shan-yu LI
Chinese Journal of Pediatrics 2007;45(3):218-219
Adolescent
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Anti-Asthmatic Agents
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therapeutic use
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Asthma
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blood
;
drug therapy
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Child
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Child, Preschool
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Female
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Glucocorticoids
;
therapeutic use
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Humans
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Infant
;
Interleukin-23
;
blood
;
Male
3.Lymphocyte study of mucosa of lacrimal drainage system.
Tao ZHANG ; Ji-qun WANG ; Yan-chun SHAN
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2005;40(10):786-787
Adult
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Female
;
Humans
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Lacrimal Apparatus
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immunology
;
Lymphocytes
;
immunology
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Male
;
Mucous Membrane
;
immunology
4.Model Case Design for Problem-based Learning in Medical Microbiology and Human Parasitology
Ji-Chun WANG ; Lan-Yan ZHENG ; Jun-Yan SHI ; En-Jie LUO ;
Microbiology 1992;0(01):-
Problem-based learning(PBL)is an important part of creative education in medical colleges.Choice and design of cases are of the vital importance to success or failure of PBL course.To enhance students' ability of independent,creative thinking,and their ability of analyzing and solving problems,the roles of primitive cases and model cases as well as interrelation between them were discussed respective- ly.Moreover,five basic principles to be followed in model case design for PBL in Medical Microbiology and Human Parasitology,i.e.objec- tivity,flexibility,consistency,illumination and relevance,were proposed in this study.
5.Identification and application of three anti-HCMVpp65 McAbs
Chun-Yan QIAN ; Sheng-Nian WANG ; Yue ZHANG ; Ying-Ying CHEN ; Yan SHI ; Yan HE ; Hao LU ; Yu-Hua JI ;
Chinese Journal of Laboratory Medicine 2001;0(02):-
0.05).Conclusion Three Hybridoma cell lines which secrete the target antibodies with satisfied affinities and specificities have been successfully raised,which provides a basis to produce a domestic-made HCMVpp65 antigen diagnosis kit.
6.Effect of Qi Benefiting Blood Activating Method on Plasma Fibrinogen and D-dimer in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease.
Sheng WANG ; Yue CHEN ; Wei REN ; Chun-dong ZHU ; Chun-ying LI ; Qun ZHOU ; Hong-yan JI
Chinese Journal of Integrated Traditional and Western Medicine 2015;35(5):537-540
OBJECTIVETo explore the therapeutic effect of qi benefiting blood activating method (QB-BAM) on acute exacerbation of chronic obstructive pulmonary disease (AECOPD) patients with blood stasis syndrome (BSS) by observing its effect on plasma fibrinogen (Fg) and D-dimer (D-D) levels.
METHODSSixty AECOPD patients with BSS were randomly assigned to the treated group and the control group, 30 in each group. All patients received conventional therapy for AECOPD. Those in the treated group were additionally injected with Shengmai Injection and Tanshinone IIA Injection. Clinical efficacy and indices including levels of Fg, D-D, PaO2, and PaCO2 were measured and compared before and after treatment.
RESULTSThe effective rate was 93.3% (28/30 cases) in the treated group, higher than that of the control group [73.3% (22/30 cases) , P < 0.05]. There was no significant difference in all indices between the treated group and the control group before treatment (P >0.05). After treatment all indices were significantly improved in the two groups (P < 0.01). But in the treated group levels of Fg and D-D decreased more and levels of PaO2 increased more (P < 0.01). Plasma levels of Fg and D-D levels were negatively correlated with PaO2 (r = -0.493, r = -0.438, P < 0.01) before treatment, and also negatively correlated with PaO2 (r = -0.452, r = -0.325, P < 0.01, P < 0.05) after treatment, but they were not significantly correlated with PaCO2 before and after treatment (P >0.05).
CONCLUSIONSQBBAM could play a therapeutic role in improving prethrombotic states of AECOPD patients with BSS. Plasma levels of Fg and D-D were related to the severity of AECOPD.
Acute Disease ; Drugs, Chinese Herbal ; therapeutic use ; Fibrin Fibrinogen Degradation Products ; Fibrinogen ; Hemostatics ; Humans ; Plasma ; Pulmonary Disease, Chronic Obstructive ; drug therapy ; Qi
7.Echocaridiographic evaluation on early left ventricular remodeling after acute myocardial infarction: experimental study
Jian, WANG ; Chun-song, KANG ; Yan-ping, ZHENG ; Ji-ping, XUE ; Rui, ZHANG
Chinese Journal of Medical Ultrasound (Electronic Edition) 2008;5(2):229-234
Objective To investigate the onset of left ventricular remodeling (LVRM) after acute myocardium infarction (AMI) and its changes within 6 hours in dogs on echocardiography. Methods AMI was induced in 14 dogs by ligating the left anterior descending arteries. Eight myocardium infarcted models were successful and were sacrified for pathological study. The indices of LVRM: wall infarction thickness (WIT), the wall motion score index (WMSI), left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV) and left ventricular ejection fraction (LVEF) were evaluated before and 1 h, 2 h, 3 h, 4 h, 5 h and 6 h after operation. Results Compared with the pre-operation, WIT and LVEF were decreased (P<0.01), LVESV and WMSI were increased (P<0.01), and LVEDV was increased (P<0.05 or P<0.01) at every time point after operation. WIT had no significant difference at 1 h, 2 h, 3 h, 4 h, 5h and 6h after operation (P>0.05). LVEDV, LVESV were higher (P<0.05) and LVEF was lower (P<0.05 or P<0.01) at 4 h, 5 h, and 6 h than at 1 h, and 2 h after operation. WMSI was higher at 3 h, 4 h, 5 h, and 6 h than at 1h (P<0.05). Conclusions In our experiment, LVRM occurred at 1 h after AMI in dogs. Thus echocardiography may evaluate early LVRM.
8.Distortion Product Otoacoustic Emissions in Normal Infants Hearing Screening
bing, LIAN ; yan-chun, SHAN ; ji-qun, WANG ; li-xin, JIANG ; long, HE
Journal of Applied Clinical Pediatrics 1993;0(03):-
Objective To investigate the usage of distortion product otoacoustic emissions(DPOAE) in normal infants hearing screening.Methods One hundred infants(200 ears) without clinical condition of illness were checked in GSI 70 DPOAE screening.The pure tones were 2,3,4 kHz,the OAE screener scored the test result as a pass,when the responses were above the PASS/REFER line and the signal-to-noise was at least 10 dB.Results Ninty-four infants(188 ears) passed hearing screening. Four infants(8 ears) with ceruminous impaction didn′t pass screening;after extracting impacted cerumen from the external auditory meatus,the 4 infants(8 ears) passed screening.Two infants(2 ears) with secretory otitis media didn′t pass screening,but after medicine treatment for 1 week,they passed screening too.Conclusion DPOAE has advantages in infants hearing screening.J Appl Clin Pediatr,2006,21(3):168-169
10.Calcinosis cutis of bilateral knees: report of a case.
Hong-ji DING ; Chun-yan LIU ; Zhi-qiang LIU ; Jing LI ; Chuan-sen ZHANG
Chinese Journal of Pathology 2012;41(12):852-853
Calcinosis
;
pathology
;
surgery
;
Child
;
Diagnosis, Differential
;
Humans
;
Knee
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Male
;
Skin Diseases
;
pathology
;
surgery