1.Treatment of Fracture
Eun Woo LEE ; Jae Myeung CHUN ; Hyun LIM
The Journal of the Korean Orthopaedic Association 1989;24(2):636-640
Pain, traumatic arthritis, joint stiffness and joint subluxation are common sequelae of fracture dislocations of the proximal interphalangeal joints of the finger. Many kinds of methods were used to treat fracture dislocation of the proximal interphalangeal joint. The prognosis is greatly influenced by the method and the time of treatment. Authors treated 4 cases of fracture dislocations of the proximal interphalangeal joint with 3 different method. For a case with small bony fragment, we used the extension block splint of McElfresh. For a old case, we used the volar plate arthroplasty mothod of Eaton. And for two cases with large bony fragment, we used the force couple splint method of Agee after open reduction and internal fixation. The results were satisfactory.
Arthritis
;
Arthroplasty
;
Dislocations
;
Fingers
;
Joints
;
Methods
;
Prognosis
;
Splints
3.Replantation of 135 fingertip amputations.
Joon Hee LEE ; Jae Ho LIM ; Jong Moon LEE ; Woo Kyung KIM ; Chun Eun CHUNG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(5):1136-1144
No abstract available.
Amputation*
;
Replantation*
4.A study on reliability of the abdominal plain film diagnosis in pediatric patients with suspected intussusception
Young Jun SUH ; Kang Woo CHUN ; Jin Sook LIM ; Jong Sup YOON
Journal of the Korean Radiological Society 1982;18(3):549-553
1. The plain abdominal films of 246 cases of intussusception preceding hydrostatic barium enema were analysedin order to reassess the diagnostic reliability of the abdominal plain film examination. Then, these were comparedwith 42 cases in which the diagnosis had been rejected by means of barium enema. 2. It was found that diagnosis ofthe intussusception was possible in 80% of 246 cases on the basis of plain film findings alone. 3. The most commonand reliable findings of intussusception in plain film diagnosis are those of sparse faecoloid bowel content andsparse amount of intestinal gas. 4. The loops of distended small bowel in cecal or ascending colon area andintraabdominal soft tissue mass are considered to be relatively reliable findings. 5. In 42 cases in which thediagnosis had been rejected by means of barium enema, intussusception was excluded in 745 of the cases on thebasis of plain film findings alone.
Barium
;
Colon, Ascending
;
Diagnosis
;
Enema
;
Humans
;
Intussusception
5.The effect of granulocyte colony-stimulating factor in chemotherapy of acute myelogenous leukemia.
Byung Chun CHUNG ; Dong Suk KWAK ; Il Jung CHOI ; Woo Jong LIM ; Kyu Bo LEE
Korean Journal of Hematology 1993;28(1):21-30
No abstract available.
Drug Therapy*
;
Granulocyte Colony-Stimulating Factor*
;
Granulocytes*
;
Leukemia, Myeloid, Acute*
6.Effect of Oncostatin M on Proliferation and Matrix Synthesis of Dermal Fibroblasts.
Kyung Wook CHUN ; Hyung Woo LIM ; Seung Kyu HAN ; Woo Kyung KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2008;35(2):115-120
PURPOSE: Oncostatin M(OSM) is a multifunctional cytokine that belongs to the interleukin(IL)-6 family. Although there have been a number of studies that focused on the role and mechanism of OSM in various organs and tissues, there are few reports on its effect on wound healing. The final purpose of this project is to evaluate the effect of OSM on wound healing. This pilot study was designed to investigate the effect of OSM on proliferation and matrix synthesis of human dermal fibroblasts, which are the major components of the wound healing. METHODS: Excess skin that was obtained from patients who underwent skin grafts, was used for this study. From this material, fibroblasts were isolated and cultured. The cultured fibroblasts were treated with one of four concentrations of OSM. The OSM concentrations used were 0, 50, 100, and 200ng/ml, respectively. After the OSM treatment, cell proliferation was determined by the MTT assay, collagen synthesis by the C1CP method, GAG levels by the Blyscan Dye method. The parameter levels of each group were compared. RESULTS: OSM treatment increased all the components tested in the study. In particular, cell proliferation, GAG synthesis demonstrated statistically significant increases(p<0.05 in the Mann-Whitney U-test). The highest increase in all the components was obtained at a 100ng/ml concentration of OSM. CONCLUSION: The results of the present study indicate that OSM stimulates proliferation and matrix synthesis of human dermal fibroblast and the optimal concentration for wound healing is 100ng/mL.
Cell Proliferation
;
Collagen
;
Fibroblasts
;
Humans
;
Oncostatin M
;
Pilot Projects
;
Skin
;
Transplants
;
Wound Healing
7.A Case of Congenital Dislocation of the Knee.
Seung Geun LIM ; Woo Jin KWON ; Sun Ki LEE ; Jae Ho HYUN ; Jin PARK ; Chun Hee WON ; Young Woo KIM
Korean Journal of Perinatology 1998;9(2):175-179
Congenital dislocation of the knee is very rare skeletal deformity and was firstly described by Chatelaine in 1822. Since then there have been a few number of case reports and some series discussing the etiology and treatment. The tibia is displaced anteriorly in relation to the femur. It is generally subdassified as simple hyperextention, subluxation, and dislocation depending on the degree of the joint displacement and the severity of disease. Early gentle manipulation and serial splintage or plaster cast are recommended for treatment and were successful in the majority except the case of quadriceps contrarture or late correction. The authors experienced one case of congenital dislocation of the right knee and brief review of the related literatures was made.
Casts, Surgical
;
Congenital Abnormalities
;
Dislocations*
;
Femur
;
Joints
;
Knee*
;
Tibia
8.Results of Arthroscopic Debridement of the Elbow Osteoarthritis.
Churl Hong CHUN ; Jung Woo KIM ; Jae Chang LIM
Journal of the Korean Shoulder and Elbow Society 2009;12(1):53-60
PURPOSE: Primary osteoarthritis on the elbow is the result of the growth of osteophytes and contracture of the capsule. It often causes disability on joint motion and pain while exercising. As arthroscopy has developed, the arthroscopic diagnosis and treatment of the elbow have recently become more generalized as well. Therefore, we like to report on arthroscopy for treating elbow arthritis and its results. MATERIALS AND METHODS: This study includes 23 cases of elbow arthritis that were seen between 2005 June to 2007 June and these patients didn't response to conservative treatment. From this we excluded 18 cases that underwent arthroscopic surgery and among these 18 cases, 6 cases underwent ulnar nerve transfer. The average observation time was 21.3 months and the average age was 48.4 years (range: 22-66 years). The pre and post operative pain was evaluated with using the Visual Analogue Scale (VAS) and functional evaluation was done with using the Mayo elbow Performance Score (MEPS) with the range of joint motion. RESULTS: The VAS score at the last follow up was significantly decreased from 3.4 to 1.9 compare to the preoperative score. The range of joint motion was improved by 25 (0-40) to 8.5 (0-20) in extension and 101.7 (80-140) to 125.2 (85-140) in flexion (p<0.05). The MEPS always showed significant improvement by showing an increase from 65.4 (40-85) to 87.9 (55-100). However, 3 cases showed a decreased range of motion after the operation. One case showed ulnar nerve symptoms after surgery. CONCLUSION: An arthroscopic procedure can treat the pathologic processes associated with arthritis of the elbow and it was safe and effective in this series.
Arthritis
;
Arthroscopy
;
Contracture
;
Debridement
;
Elbow
;
Follow-Up Studies
;
Humans
;
Joints
;
Osteoarthritis
;
Osteophyte
;
Pathologic Processes
;
Range of Motion, Articular
;
Ulnar Nerve
9.Leptin and adiponectin levels in girls with central precocious puberty before and during GnRH agonist treatment.
Jae Won YOO ; Chun Woo SONG ; Han Hyuk LIM
Annals of Pediatric Endocrinology & Metabolism 2016;21(4):199-205
PURPOSE: The effects of gonadotropin-releasing hormone agonist (GnRHa) treatment on the energy metabolism in girls with central precocious puberty (CPP) are controversial. We focused the changes and related factors of serum levels of leptin and adiponectin in girls with CPP before and during GnRHa treatment. METHODS: Thirty girls with idiopathic CPP were enrolled in the study. Their auxological data and fasting blood were collected at the baseline and after six months of GnRHa treatment. RESULTS: After treatment, height (P<0.001), weight (P<0.001), and serum leptin levels (P=0.033) were significantly increased, whereas body mass index (BMI), homeostasis model of assessment-insulin resistance, serum adiponectin levels, and adiponectin/leptin ratio exhibited no significant changes. A Pearson correlation analysis showed that height, weight, BMI, and their standard deviation scores (SDSs), but not basal LH, FSH, and estradiol, were significantly correlated with serum leptin levels before and after GnRHa treatment. After a multiple linear regression analysis, only BMI was associated with serum leptin levels. Moreover, leptin SDSs adjusted for BMI were not significantly different before and after GnRHa. The Δ leptin levels (r2=0.207, P=0.012), but not with Δ leptin SDS (r2=0.019, P=0.556), during GnRHa treatment were positively correlated with Δ BMI. CONCLUSION: These results suggest that GnRHa treatment in girls with CPP does not affect serum levels of leptin and adiponectin and insulin resistance. Serum leptin levels were depend on the changes in BMI during GnRHa treatment.
10.Leptin and adiponectin levels in girls with central precocious puberty before and during GnRH agonist treatment.
Jae Won YOO ; Chun Woo SONG ; Han Hyuk LIM
Annals of Pediatric Endocrinology & Metabolism 2016;21(4):199-205
PURPOSE: The effects of gonadotropin-releasing hormone agonist (GnRHa) treatment on the energy metabolism in girls with central precocious puberty (CPP) are controversial. We focused the changes and related factors of serum levels of leptin and adiponectin in girls with CPP before and during GnRHa treatment. METHODS: Thirty girls with idiopathic CPP were enrolled in the study. Their auxological data and fasting blood were collected at the baseline and after six months of GnRHa treatment. RESULTS: After treatment, height (P<0.001), weight (P<0.001), and serum leptin levels (P=0.033) were significantly increased, whereas body mass index (BMI), homeostasis model of assessment-insulin resistance, serum adiponectin levels, and adiponectin/leptin ratio exhibited no significant changes. A Pearson correlation analysis showed that height, weight, BMI, and their standard deviation scores (SDSs), but not basal LH, FSH, and estradiol, were significantly correlated with serum leptin levels before and after GnRHa treatment. After a multiple linear regression analysis, only BMI was associated with serum leptin levels. Moreover, leptin SDSs adjusted for BMI were not significantly different before and after GnRHa. The Δ leptin levels (r2=0.207, P=0.012), but not with Δ leptin SDS (r2=0.019, P=0.556), during GnRHa treatment were positively correlated with Δ BMI. CONCLUSION: These results suggest that GnRHa treatment in girls with CPP does not affect serum levels of leptin and adiponectin and insulin resistance. Serum leptin levels were depend on the changes in BMI during GnRHa treatment.