No abstract available.
Adenoma, Pleomorphic*

There are several ELISA(enzyme linked immunosobent assay) kits to be highly sensitive and specific in the screening test for antibodies to HIV. However, these have several problems such as high false-positive rate, low reproducibility and complex test procedures. A new serological test, the gelatin particle agglutination test(PAT), was developed and reported as good test having the same sensitivity with ELISA, and simple and easy procedure. The purpose of this study is com parison of two screening tests, ELISA and PAT, for detection of antibodies to HIV In one hundred two prostitutes, who used to contact with foreigners such as U.S. army personels, 10 syphilitic patients in Chonnam University hospital and 3 HIV infected patients, the serological results were equal in both tests, so there. was 100% concordance rate of seroreactivity between ELISA and PAT. Among 13 serum samples with false positive in ELISA test, only one sample revealed also reactive in PAT, which suggest indirectly us for PAT to be more specific than ELISA. The quantitative test with PAT of 4 consecutive serums during 4 months in the AIDS patient with Kaposi's sarcoma. However, in overall serum titer, the AIDS patient was higher than asymptomatic infected person. Thus the PAT test should be also useful for the mass screcning and quantitative test of anti-HIV antibody, and is highly recommedable for detection of HIV infection because the test can be performed with simple procedure and techique in addition ecoomically low cost and shortened time for the test.
Agglutination ; Antibodies ; Emigrants and Immigrants ; Enzyme-Linked Immunosorbent Assay* ; Gelatin ; HIV ; HIV Infections ; Humans ; Jeollanam-do ; Mass Screening* ; Sarcoma, Kaposi ; Serologic Tests ; Sex Workers

Mycetoma is a clinical syndrome of localized, indolent, deforming, swollen lesions and sinuses, involving cutaneous and subcutaneous tissues, fascia, and bone. Its lesions. are composed of suppurat.ing abscesses, granulomata, and dra ning sinuses and the etiologic agents are wide variety of bacteria (actinomycotic mycetoma) and fungi(eumcotic mycetoma) from plant and soil. The patient was a 65-year-old female and a farnier. She was referred by the skin lesion loalized on the dorsum of her lefther left hand and wrist for three months. It showed multiple subcutaneclis nodules, abscesses, and discharging fitula based on the erythematous plaque. The skin biopsy frorn the lesion revealed the PAS positive hyphae in the granulocytic infiltration. Fungus cult,ure with a piece of tissue on sabouraud media shows hin, floccose, white colonies. Slide culture and biochemical idcrtification of pathogen led to the final diagnosis as Mycetoma caused by Pseudallescheria boydii(Monosporium apiospermum). The lesions disappeared gradualy following systemic oral administratior of Itraconazole 200mg daily for six weeks.
Abscess ; Aged ; Bacteria ; Biopsy ; Diagnosis ; Fascia ; Female ; Fungi ; Hand ; Humans ; Hyphae ; Itraconazole ; Mycetoma* ; Plants ; Pseudallescheria* ; Skin ; Soil ; Subcutaneous Tissue ; Wrist

Multiple satellite pyogenic granuloma developed on the left upper back of a 14-year-old boy after excision of a hemangioma-like lesion. He has had nevus flammeus on the left upper arm since birth with fine linear telangietasiae around the main lesions. Histopathology showed the capillary proliferation in the dermis, and transmission electron microscopy revealed multiple Weibel-Palade bodies, considered an early endothelial cell marker, in the cytoplasm of the endothelial cells. We believe this patient may have the propensity to develop different angiomatous lesions.
Adolescent ; Arm ; Capillaries ; Cytoplasm ; Dermis ; Endothelial Cells ; Granuloma, Pyogenic* ; Humans ; Male ; Microscopy, Electron, Transmission ; Parturition ; Port-Wine Stain ; Weibel-Palade Bodies

No abstract available.
Pulmonary Embolism*

Weber-Christian diaease is characterized by recurrent crops of subcutaneous nodules or plaques which occur during febrile periods and usually has spontaneous regression. Since the earlier case reports there have been instances of nodular panniculitis affecting visceral fat as well as the subcutaneous tissue. Death may rarely occur follow ing visceral involvement. We experienced a fatal case of Weber-Christian disease in a 32 year old female, who had prominent hepatomegaly and leukopenia accompanied by various general symptoms such as nausea, vomiting, abdominal pain, and cough. This case also had unusually large erythematous swelling of the face and aMomen in addition to multiple subcutaneous nodules in the extremities and trunk.
Abdominal Pain ; Adult ; Cough ; Extremities ; Female ; Hepatomegaly ; Humans ; Intra-Abdominal Fat ; Leukopenia ; Nausea ; Panniculitis ; Panniculitis, Nodular Nonsuppurative* ; Subcutaneous Tissue ; Vomiting

We report a case of a 41-year-old female with acrogeria. She was in good health except for the prominent atrophy over the hands and feet. On microscopic examination of a biopsy specimen from the atropl6c skin, elastic fibers were clumped and fragmented. Electronmicroscopy revealed amorphous and granulous pseudoelastin, which is presumed to be consistent with acrogeria. Our patient had acro-osteolysis and an extra chromosome in addition to the normal 23 pairs of chromosomes in one of 20 cells examined, which have been very rarely reported in the literature. Further studies are needed to find out whether this chromosomal aberration might contribute to the pathogenesis.
Acro-Osteolysis ; Adult ; Atrophy ; Biopsy ; Chromosome Aberrations ; Elastic Tissue ; Female ; Foot ; Hand ; Humans ; Skin

We present two cases of lymphangioma circumscriptum according to the clinical pattern and histopathological findings, one with lesions on the tongue and the other with lesions of the oral mucous membrane. The first case was a 5 year-old boy with a plaque of grouped transluscent vesicles resembling frog's spawn on ventral surface of the tongue of three years duration. The second case, also a 5 year-old boy, had a lymphangioma circumscriptum lesion in the right buccal mucous membrane which developed several months after birth and eventually produeed swelling of the right cheek. The histopathological findings of both cases showed variable-sized dilated lymphatic channels lined by one layer of normal endothelial cells, extending to the deep dermis, subcutaneous tissue and muscle layer and resembling the spongy type variant of classical lymphangoima circumscriptum using the classification of lymphangioma of Peacheyet al.
Cheek ; Child, Preschool ; Classification ; Dermis ; Endothelial Cells ; Humans ; Lymphangioma ; Male ; Mouth* ; Mucous Membrane ; Parturition ; Subcutaneous Tissue ; Tongue

No abstract available.
Hemorrhoids*

Cutis naarmorata telangiectatica congenita(CMTC) was first lesribed by Van Lohuizen in 1992. Cases of CMTC were reported later under various names, includir gan Lohuizens syndrome, congenital generalized phlebectasia. congential phlebectasia and reticulatever scular nevus. It is charaterized by persistent livedo reticularis, telangiectasia and phlectnsia from birch hand atrophy and superficial ulceration of the overlying skin are uncornmonly encountered. They have a steady improvement with time, however various congenital abnormalties, such as varicosities, hen ariomas, hypoplasia or hypertrophy of soft tissue and bones, rarely generalized congenital fibrornatos ectal and genital anomaliies may be associated in approxirnately 50 percent of patients. In case 1, the patient was 45-day-old female infant with reticulated mottling and atrophy of the skin on the right leg. In case 2, the patient was 30-day-old male infant who depressed, bluish, and reticulated patches on the both upprarms, right side trunk, buttock and loen leg. Decreased circumferences of the affected extremities vas observed in case 2. No other assotated anomalies were found in physical and X-ray examinatiorwlin both cases. The skin biiopsy of bothed similar findings, which revealed mild dilatation and proliferation of capillaries, mild inflammatoryel infiltration and extravasated red blood cells in the dermis. The clinical follow-up, alneast all of th lisions disappeared spont.anously in 1 year at case 1, and some of lesions also disappeared in 3 month, 11 case 2. In addition, we reviewed and summerized the reported cases in Korea.
Atrophy ; Betula ; Buttocks ; Capillaries ; Dermis ; Dilatation ; Erythrocytes ; Extremities ; Female ; Follow-Up Studies ; Hand ; Humans ; Hypertrophy ; Infant ; Korea ; Leg ; Livedo Reticularis ; Male ; Nevus ; Skin ; Telangiectasis ; Ulcer