We present a case of erosive adenomatosis of the nipple in a 22-year-old woman. The clinical features of erosive adenomatosis of the nipple are similar to Paget's disease in that it has erythematous erosions with oozing and fissured crusts on one nipple. However, histologic findings are characteristic, consisting of dilated tubular structures that are lined by a peripheral layer of cuboidal cells and a luminal layer of columnar cells showing secretary properties into the lumen. The clinical course is benign, so simple mastectomy is enough for treatment.
Female ; Humans ; Mastectomy, Simple ; Nipples* ; Phenobarbital ; Young Adult

Aneurysmal fibrous histiocytoma(AFH) is a histologic variant of dermatofibroma. The importance of the recognition of AFH as a variant of dermatofibroma lies in the differential diagnosis because the histologic appearance of AFH is very similar to dermatofibrosarcoma protuberans and other vascular malignancies, such as Kaposi's sarcoma and angiosarcoma. A 32-year-old man was seen for a nodular mass on the right popliteal fossa of 4 years' duration. The excisional biopsy specimen showed a relatively well circumscribed tumor mass in the dermis. In addition to compact storiform proliferation of spindle cells, there were multiple, irregular, blood-filled, aneurysmal tissue spaces that were devoid of lining of endothelial cells. Also, deposition of hemosiderin was prominent, particularly in the periphery of the aneurysmal spaces. Immunohistochemical stain for CD34 were negative to most tumor cells. After excisional therapy, there was no evidence of recurrence during the period of ten months' follow-up.
Adult ; Aneurysm* ; Biopsy ; Dermatofibrosarcoma ; Dermis ; Diagnosis, Differential ; Endothelial Cells ; Follow-Up Studies ; Hemangiosarcoma ; Hemosiderin ; Histiocytoma, Benign Fibrous* ; Humans ; Recurrence ; Sarcoma, Kaposi

Congenital branchial anomalies are developmental defects resulting from incomplete obliteration of branchial clefts, arches and pouches, and usually found as cysts, fistulas and sinuses. The sinus or fistula is usually noted during infancy and young childhood due to recurrent infection. We have experienced a case of branchial cleft fistula in a 12-year-old male. It was a skin colored, nontender nodule which had mucus secreting from a small opening pore. We performed complete surgical removal and histopathologically the lumen was lined by pseudostratified columnar cells and the stroma was composed of aggregates of lymphocytes with many germinal centers. So we finally diagnosed it as branchial cleft fistula of second type branchial anomaly.
Branchial Region* ; Child ; Fistula* ; Germinal Center ; Humans ; Lymphocytes ; Male ; Mucus ; Skin

PURPOSE: This study was to examine the effects of an exercise program on physical fitness, cardiopulmonary function and life satisfaction for adult women. METHOD: The exercise program combined dance and resistance training. The subject group consisted of 114 women aged between 33 and 60. Three 8-week sessions consisted of 55-80% HR max for 60-90 minutes a day and 3 times a week from March to November, 2004. Data were collected through pre- and post-exercise tests before and after each session. Data were collected with dynamometer, sphygmomamometer, spirometer and structured questionnaires. Data were analyzed employing descriptive statistics and paired t-test with SPSS/PC(10.0version) program. RESULTS: There were significantly positive changes in muscle strength, flexibility, balance quality, forced vital capacity and life satisfaction, but no significantly positive changes in agility and blood pressure. CONCLUSION: This study showed that an exercise program has partially positive effects for adult women. The results of this study suggest that there should be programs of continuous exercise at community health centers for adult women's health.
Adult* ; Blood Pressure ; Community Health Centers ; Female ; Humans ; Muscle Strength ; Physical Fitness* ; Pliability ; Resistance Training ; Vital Capacity ; Women's Health ; Surveys and Questionnaires

This study evaluated the antibacterial effects of a mixture of Sophorae radix and Glycyrrhiza uralensis Fischer (1 : 1) ethanol extracts (SGE) on mice infected with Streptococcus (S.) pyogenes. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration of SGE necessary for antibacterial effects against S. pyogenes were 20 microg/mL. Based on the time-kill curves for S. pyogenes, SGE was effective at 4x MIC after 16 h. On Day 12 after challenge, the survival rate of mice treated with 2.0 mg/kg SGE was 60%. In conclusion, SGE had potent in vitro and in vivo antibacterial activities against S. pyogenes.
Animals ; Complex Mixtures ; Ethanol* ; Glycyrrhiza uralensis* ; Mice* ; Microbial Sensitivity Tests ; Plants, Medicinal ; Sophora* ; Streptococcus ; Streptococcus pyogenes* ; Survival Rate ; Treatment Outcome

This study evaluated the antibacterial effects of a mixture of Sophorae radix and Glycyrrhiza uralensis Fischer (1 : 1) ethanol extracts (SGE) on mice infected with Streptococcus (S.) pyogenes. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration of SGE necessary for antibacterial effects against S. pyogenes were 20 microg/mL. Based on the time-kill curves for S. pyogenes, SGE was effective at 4x MIC after 16 h. On Day 12 after challenge, the survival rate of mice treated with 2.0 mg/kg SGE was 60%. In conclusion, SGE had potent in vitro and in vivo antibacterial activities against S. pyogenes.
Animals ; Complex Mixtures ; Ethanol* ; Glycyrrhiza uralensis* ; Mice* ; Microbial Sensitivity Tests ; Plants, Medicinal ; Sophora* ; Streptococcus ; Streptococcus pyogenes* ; Survival Rate ; Treatment Outcome

This study investigated the effects of LactoPlanta(R) (Lactobacillus plantarum (L. plantarum), 2.0 x 10(9) colony forming units (CFU)/kg) on reduction of noxious gas emission in pig houses as well as improvement of carcass weight and quality in finishing pigs. A total of 850 finishing pigs were assigned to four treatment groups: control (CON, basal diet) (n=190), LP-0.1, 0.1% LactoPlanta(R) (n=210), LP-0.2, 0.2% LactoPlanta(R) (n=230), and LP-0.4, 0.4% LactoPlanta(R) (n=220). Ammonia and hydrogen sulfide concentrations were significantly reduced in all treatment groups compared to CON. Mercaptan contents and carcass weights of LP-0.2 and LP-0.4 were significantly decreased compared to CON, whereas there were no significant differences between LP-0.1 and CON. Carcass weight of LP-0.1 was slightly higher than that of CON, but there was no significant difference. However, carcass weights of LP-0.2 and LP-0.4 were significantly higher than that of CON (P<0.05). The prevalence of grade A carcasses in groups administered with L. plantarum (46.7~63.3%) was higher than that in CON (43.3%) and increased in a dose-dependent manner. Based on the results of this study, L. plantarum could be an effective candidate to reduce noxious gas emissions in finishing pig houses as well as improve carcass weight and quality in finishing pigs.
Ammonia ; Hydrogen Sulfide ; Lactobacillus plantarum* ; Prevalence ; Stem Cells ; Swine* ; Weights and Measures

This study was conducted to analyze penicillin G (PEG), streptomycin (STR) and neomycin (NEO) residues in milk of healthy lactating cows. Milk samples were collected from all four quarters of 12 dairy cows 2–7 days after intramammary infusions of an ointment containing PEG, STR and NEO once (n = 4; group I) or twice (n = 4, group II) daily. Ultra-performance liquid chromatography coupled with electrospray tandem mass spectrometry was used to determine the antibiotic residues in the samples. The correlation coefficient (r 2) of the calibration curves for all antibiotics was > 0.999 and the limits of detection and quantification were 0.002–0.005 µg/mL and 0.007–0.02 µg/mL, respectively. Recovery rates were ranged from 75.5 to 92.3%. In group I, PEG, STR and NEO residues were detected in milk at 2, 3 and 2 days post-treatment, respectively, which were below the maximum residue limit (MRL). In group II, PEG, STR and NEO residues were detected in milk at 2, 3 and 3 days post-treatment, respectively, which were bellow the MRL. These results suggest that a 3-day for milk withdrawal period after the ointment treatment might be sufficient for reduction of the antibiotic residues below the MRL.

OBJECTIVES: To integrate the results of studies which assess an association between blood lead and blood pressure. METHODS: We surveyed the existing literature using a MEDLINE search with blood lead and blood pressure as key words, including reports published from January 1980 to December 2000. The criteria for quality evaluation were as follows: 1) the study subjects must have been workers exposed to lead, and 2) both blood pressure and blood lead must have been measured and presented with sufficient details so as to estimate or calculate the size of the association as a continuous variable. Among the 129 articles retrieved, 13 studies were selected for quantitative meta-analysis. Before the integration of each regression coefficient for the association between blood pressure and blood lead, a homogeneity test was conducted. RESULTS: As the homogeneity of studies was rejected in a fixed effect model, we used the results in a random effect model. Our quantitative meta-analysis yielded weighted regression coefficients of blood lead associated with systolic blood pressure and diastolic blood pressure results of 0.0047 (95% confidence interval [CI]: -0.0061, 0.0155) and 0.0004 (95% CI: -0.0031, 0.0039), respectively. CONCLUSIONS: The published evidence suggested that there may be a weak positive association between blood lead and blood pressure, but the association is not significant.
Blood Pressure*

BACKGROUND: Various regimens have been studied in extension of a preexisting labor epidural for emergency cesarean section. Lumbar epidural analgesia for delivery is safe and efficient. We compared retrospectively 0.5% ropivacaine with fentanyl and 0.75% ropivacaine in extension of a preexisting labor epidural for emergency cesarean section. METHODS: We investigated medical records of 61 parturients in extension of a preexisting labor epidural for emergency cesarean section. There were two regimens which was 0.5% ropivacaine with fentanyl (group 1) and 0.75% ropivacaine (group 2). We recorded demographic data, local anesthetic dose, surgical readiness time, maximum level of sensory block, surgery time, intravenous supplementation, number of hypotension and total dose of ephedrine between two groups. RESULTS: There were no differences between the study groups in demographic data, surgical readiness time, maximum sensory block level, intravenous supplementation, incidence of hypotension and total dose of ephedrine. Local anesthetic volume was larger in group 1 than group 2, but local anesthetic doses were lower in group 1 than group 2. CONCLUSIONS: 0.5% Ropivacaine with fentanyl regimen is as fast and efficacious as 0.75% ropivacaine in extension of a preexisting labor epidural for cesarean section and reduces the requiring total local anesthetic dose.
Analgesia, Epidural ; Cesarean Section* ; Emergencies* ; Ephedrine ; Female ; Fentanyl* ; Hypotension ; Incidence ; Medical Records ; Pregnancy ; Retrospective Studies*