1.The clinical observation and automatic function test in patients with abnormal sensation in the throat: measurement of coefficiencyof variation of R-R intervals in ECG.
Chun Keun PARK ; Seong Kook PARK ; Eun Pyo PARK
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(5):1018-1034
No abstract available.
Electrocardiography*
;
Humans
;
Pharynx*
;
Sensation*
2.Malingering test by evaluation of pure tone ascending-descending gap.
Chun Keun PARK ; Sang Cheol LEE ; Gun Joo LEE
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(1):53-60
No abstract available.
Malingering*
3.Clinical analysis of 8 cases of the head and neck reconstruction using pectoralis major myocutaneous flaps.
Jae Wook EOM ; Seong Kook PARK ; Eun Pyo PARK ; Chun Keun PARK
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(4):567-571
No abstract available.
Head*
;
Myocutaneous Flap*
;
Neck*
4.A case of malignant external otitis using scintigraphic study.
Chun Keun PARK ; Sang Hyeon KIM ; Eun Pyo PARK ; Seong Kook PARK
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(6):925-929
No abstract available.
Otitis Externa*
5.Taste function in the patients with chronic otitis media and changes after chorda tympanic nerve section.
Sang Cheol LEE ; Seong Kook PARK ; Gun Joo LEE ; Chun Keun PARK
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(6):1186-1194
No abstract available.
Humans
;
Otitis Media*
;
Otitis*
6.Effect of STEL-toluene on Metabolism of Benzene in Rats.
Jaehoon ROH ; Dong Chun SHIN ; Jung Gyun PARK ; Young Hahn MOON ; Ho Keun CHUNG
Korean Journal of Preventive Medicine 1988;21(1):152-162
Benzene and toluene, which are widely used aromatic hydrocarbons in workplace, are recently proved to cause health hazards due to their toxic effects. This study investigated the influence of toluene on the urinary excretion of benzene metabolite by administering short term exposure limit(STEL) of these compounds(i.e., 13.8mg/kg of benzene and 108.8mg/kg of toluene) intraperitoneally into Sprague-Dawley rats. After administration, urinary phenol concentration of rat was measured by gas chromatography for every three hours. Data were analyzed by non-parametric statistical methods using Kruskal-Wallis multi-sample test and Mann-Whitney U test. The following results were obtained: 1. Administration of STFL-benzene increased urinary phenol concentration in rats. 2. Urinary phenol concentration was increased logarithmically according to the dosage of benzene. 3. Excretion of phenol in urine was decreased when benzene and toluene were administered simultaneously compared with administering benzene alone. In Summary, these results reveal that administration of STEL of toluene has antagonistic effect of urinary excretion of benzene metabolite in rats.
Animals
;
Benzene*
;
Chromatography, Gas
;
Hydrocarbons, Aromatic
;
Metabolism*
;
Phenol
;
Rats*
;
Rats, Sprague-Dawley
;
Threshold Limit Values
;
Toluene
7.A Comparison Study of the Staphylococcal Exotoxins and Staphylococcal Enterotoxin A-specific IgE Antibody between Childhood and Adulthood Atopic Dermatitis.
Hyun Wook KIM ; Chun Wook PARK ; Cheol Heon LEE ; Won Keun SONG
Annals of Dermatology 2003;15(3):99-100
BACKGROUND: The skin of patients with atopic dermatitis (AD) exhibits a striking susceptibility to colonization with Staphylococcus aureus (S. aureus). Superantigens produced by S. aureus and their specific IgE antibodies are thought to be important precipitating factors of AD, but there are few reports evaluating these 2 factors at the same time, particularly in adult AD patients. OBJECTS: Our purpose was to investigate the differences in the culture degree of S. aureus from the lesion, non-lesion, and control group of child and adult AD patients, to research the correlation between the exotoxin production, total IgE, anti-SEA IgE and the disease severity by SCORAD index, to ascertain the differences between child and adult AD patients. METHODS: The clinical severity of 30 child (2 to 15 years of age) and 30 adult patients (16 to 40 years of age) with AD was evaluated by using SCORAD index. S. aureus was isolated from lesional and non-lesional skin of AD patients, and from healthy controls. Staphylococcal exotoxins were detected by using reversed passive latex agglutination toxin detection kits. Anti-SEA IgE antibody was determined by using AlaSTATt assay RESULTS: S. aureus colonizations were found in 11 (36.7%) of the lesional skin, in 5 (16.7%) of the non-lesional skin of 30 child AD patients, and in 26 (86.7%), in 20 (66.7%) of 30 adult AD patients, respectively. The colonization rates of S. aureus in child patients were much lower than those in adult patients, both form lesional skin and non-lesional skin. Staphylococcal exotoxins were detected in 5 (45.5%) of the 11 colonizations from lesional skin, in 2 (40%) of the 5 colonizations from non-lesional skin of children, and in 10 (38.5%) of the 26 colonizations, in 9 (45%) of the 20 colonizations of adults, respectively. Staphylococcal enterotoxin A (SEA) was most frequently detected in both groups. S. aureus colonization was correlated with the severity of AD in childhood, but not in adulthood. However, there were no statistical significances between severity of AD and others such as exotoxin production, and the level of total IgE and anti-SEA IgE in both groups. CONCLUSION: The colonization of S. aureus was more common in adult AD patients than child AD patients. Anti-SEA IgE level was much higher in adult AD patients than in child AD patients. It is tempting to speculate that the colonization of S. aureus and exotoxin production might be related to the disease. duration rather than clinical severity of AD.
Adult
;
Agglutination
;
Antibodies
;
Child
;
Colon
;
Dermatitis, Atopic*
;
Enterotoxins*
;
Exotoxins*
;
Humans
;
Immunoglobulin E*
;
Latex
;
Precipitating Factors
;
Skin
;
Staphylococcus aureus
;
Strikes, Employee
;
Superantigens
8.Favorable effect of chemotherapy with BAM-M in mycosis fungoides.
Sang Keun HA ; Min Ah PARK ; Young Ho WON ; Inn Ki CHUN
Korean Journal of Dermatology 1993;31(4):643-648
Mycosis fungoides is an unusual malignancy of helper T-lymphocyte origin which presents initiaily with skin disease and progresses to the lymph nodes, peripheral blood. and viseral organs, and frequently results in death. A 51-year-old woman was admitted to the hospital in October, 1930 for the evaluation of a painful reddish brown tumor with ulceration of 6 months duration on the abdomen. Lymphadenopathy was not present, and routine laboratory examinations revealed negative or, within normal limits. She was diagnosed as mycosis fungoides with stage IIb according to the commirtee on staging and classification of cutaneous T-cell lymphoma, and treated with chemotherapy;regimen, BAM-M consisted of Bleomycin, Adriamycin, Methotrexate and topical nitrogen mustard. she achieved complete remission of the tumor with five cycles of BAM-M chemotherapy. We report favorable response after BAM-M chemotherapy in a pacent with advanced stage of mycosis fungoides(TNM IIb).
Abdomen
;
Bleomycin
;
Classification
;
Doxorubicin
;
Drug Therapy*
;
Female
;
Humans
;
Lymph Nodes
;
Lymphatic Diseases
;
Lymphoma, T-Cell, Cutaneous
;
Mechlorethamine
;
Methotrexate
;
Middle Aged
;
Mycosis Fungoides*
;
Skin Diseases
;
T-Lymphocytes, Helper-Inducer
;
Ulcer
9.Clinical study on trophoblastic disease.
Sun Woo KIM ; Hee Song CHUN ; Hyung Sun KIM ; Young Lee KIM ; Shin Keun PARK
Korean Journal of Obstetrics and Gynecology 1993;36(7):1058-1067
No abstract available.
Trophoblasts*
10.Analysis of Viral Phenotype (SI / NSI) and V3 Domain Amino Acid Sequence in the Various HIV - 1 Subtype Isolates.
Jeong Gu NAM ; Chun KANG ; Sung Rae LEE ; Yong Keun PARK ; Joo Shil LEE
Journal of Bacteriology and Virology 2001;31(1):71-83
No abstract available.
Amino Acid Sequence*
;
HIV*
;
Phenotype*