3.Reconstruction of facial nerve defect in parotidectomy of parotid carcinoma using sternocleidomastoid muscle-great auricular nerve flap
Zhao-Hui WANG ; Chun-Hua LI ; Jin CHEN ; Wei WANG ;
Chinese Journal of Microsurgery 2006;0(05):-
Objective To develop the clinical application and the method for functional repair in fa- cial nerve defect in parotideetomy of parotid carainoma.Methods Defect of facial nerve in parotidectomy was repaired by transplantation of sternocleidomastoid muscle-great auricular nerve flap with anastomosis of great auricular nerve-facial nerve under microscope.Results Eight eases of facial nerve defect in parotid carcinoma were repaired by this method.The facial nerve function almost recovered and access to normal dur- ing 3 to 6 month after operation in this series.6 of 8 patients achieved a gradeⅡ,2 of 8 patients achieved a gradeⅢ.Conclusion Reconstruction of facial nerve defect using sternocleidomastoid muscle-great auricu- lar nerve flap can provide better blood supply for the plerosis and regeneration of nerve.The nerve flap also ac- celerate the functional recovery after nerve grafting.
4.Study of gene expression of heat shock protein70 induced by lead.
Jing ZHANG ; Ke-Ming LIU ; Chun-Hua WANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2008;26(12):752-754
Animals
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Cells, Cultured
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Female
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HSP70 Heat-Shock Proteins
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genetics
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metabolism
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Humans
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Lead
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pharmacokinetics
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toxicity
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Liver
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metabolism
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Male
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RNA, Messenger
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genetics
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Rats
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Rats, Wistar
5.Killing effect of IL-12-activated A-NK cells on human hepatocellular carcinoma HepG-2 cells in vitro.
Zhi-Hua WANG ; Dong-Lu ZHAO ; Chun-Yan ZHANG
Chinese Journal of Oncology 2007;29(6):423-424
Animals
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Carcinoma, Hepatocellular
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blood supply
;
pathology
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therapy
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Cell Line, Tumor
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Cells, Cultured
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Cytotoxicity, Immunologic
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immunology
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Female
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Humans
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Interleukin-12
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pharmacology
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Interleukin-2
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pharmacology
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Killer Cells, Natural
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cytology
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drug effects
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immunology
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Liver Neoplasms, Experimental
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blood supply
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pathology
;
therapy
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Lymphocyte Activation
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drug effects
;
immunology
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Male
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Mice
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Mice, Inbred BALB C
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Mice, Inbred C57BL
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Microcirculation
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drug effects
;
Random Allocation
;
Xenograft Model Antitumor Assays
7.Influence of Feeding Styles in Early Stage on Children′s Weight in Different Stages
he-ru, WANG ; chun-hua, JIN ; jian-na, ZHANG
Journal of Applied Clinical Pediatrics 2006;0(21):-
Objective To explore the influence of feeding styles in early stage on children′s weight in different stages.Methods A complete record of 918 healthy infants was selected and then divided into 3 feeding groups:breast feeding, mixed feeding and artificial fee-ding, according to the way of feeding in the first 6 months after birth. Their weights and heights were measured in the 3rd,5th,8th,12th,18th,24th,60th month to conduct the Z score of weight for age (WAZ), weight for height (WHZ) and the body mass index (BMI) of 60-month-old infants.An investigation on the time of adding auxiliary food was conducted.Results The heavier,WAZ and WHZ of breast feeding group in the 3rd month were higher than the other groups,and the differences were statistially significant(F=4.12, 5.66, 5.79 Pa
8.Correlation between ultrasonic characteristics of carotid artery plagues and risk factors of diabetes mellitus type 2
Zhen-zhen, CHENG ; Jian-hua, WANG ; Gui-chun, DING
Chinese Journal of Medical Ultrasound (Electronic Edition) 2013;(6):465-469
Objective To evaluate the relationship between carotid artery plagues and the clinical risk factors in patients with diabetes mellitus type 2 by observing the ultrasonic characteristics of carotid atherosclerosis plagues.Methods The ultrasound results of carotid arteries in 665 patients with diabetes mellitus type 2 from January 2009 to December 2011 in Beijing Amery General Hospital were retrospectively analyzed.The location and quantity of carotid atherosclerotic plaques were observed .The relationship between the occurrence and risk factors of diabetes such as hypertension ,family history of diabetes and age were analyzed.Single factor and multi-factor analysis were applied for the related risk factors .Results The ultrasonography showed 405 cases of carotid artery plaques.Most carotid artery plaques were located in the posterior wall of carotid sinus and were hyperechoic ,hypoechoic or isoechoic.The single factor analysis showed hypertension,family history of diabetes and age are risk factors of carotid atherosclerosis (χ2 =42.322,9.682 and 140.658,all P<0.01).Multi-factor logistic regression analysis showed age was an independent risk factor of carotid atherosclerosis in patients with diabetes mellitus type 2.The risk factors scores of patients who were less than 45 years,45-65 years and over 65 years of age were (3.50 ±1.16)scores,(3.46 ±0. 92)scores and (3.21 ±0.88)scores,and the difference was statistically significant (F=5.781,P<0.001). There were significant differences between risk factors scores of different age groups ( t =2.084,2.002, 3.786,3.474,2.877 and 2.504,all P<0.05).In patients more than 65 years of age,the risk of atherosclerosis plaques is 28.732 times higher than that of patients less than 45 years of age.After controlling the age factor,the possibility of atherosclerosis plaque increased 1.201 times for each additional one point of score. Conclusions Most carotid artery plaques in patients with diabetes mellitus type 2 are located in the posterior wall of carotid sinus and are hyperechoic ,hypoechoic or isoechoic.Age is an independent risk factor for the formation of carotid plaque.Patients more than 45 years of age should undergo early intervention to avoid the occurrence of major vascular complications .
9.The design and implementation of real-time MPEG-2 video transmission in telemedicine system.
Chinese Journal of Medical Instrumentation 2002;26(6):427-429
It is particularly important for telediagnosis to transmit diagnostic video in real time. Firstly, we introduce image compression, multithread and multicast technology, then a solution is provided for the real-time video transmission system based on TCP/IP LAN.
Computer Communication Networks
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Data Compression
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methods
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Diagnosis, Computer-Assisted
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Equipment Design
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Image Processing, Computer-Assisted
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Software
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Telemedicine
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instrumentation
;
trends
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Video Recording
;
instrumentation
10.The expression of Foxp3 and transforming growth factor-β1 is correlated with the activity of systemic lupus erythematosus
Hua YE ; Chenxian DAI ; Chun LI ; Shiyao WANG ; Zhanguo LI
Chinese Journal of Rheumatology 2009;13(9):592-594
Objective To clarify the relation between the expression of Foxp3 in peripheral blood and plasma transforming growth factor betal (TGF-β1) and the activity of systemic lupus erythematosus (SLE). Methods Foxp3 mRNA expression of 28 active SLE patients, 13 inactive SLE patients and 16 healthy controls was determined by polymerase chain reaction. Active SLE patients were followed up; Foxp3 mRNA expression of 20 active patients was measured in the stable status and the plasma TGF-β1 was measured by ELISA in the active and stable status. Results The active SLE patients showed reduced levels of Foxp3 mRNA than the inactive SLE patients (P<0.01) and the healthy controls(P<0.01). Expression of Foxp3 mRNA and the plasma level of TGF-β1 in 20 SLE patients were both higher in stable status than in active status, Conclusion The expressions of Foxp3 mRNA in peripheral blood and TGF-β1 in plasma has significant inverse corelation with disease activity, which suggests that regulatory T cells may play an important role in the pathogenesis of SLE.