We report three cases of hereditary hemorrhagic telangiectasia in one family. The punctiform, spider-like and nodular telangieectatic lesions were presented in these all patients, the father, son an daughter. But nevus flammeus-like lesion which was the unusual manifestation of hereditary hemorrhagic telangiectasia was noticed on daughters chest. There were no abnormal laboratory findings and no evidence of systemic disease. Histological findings showed only dilated telangiectatic blood vessels in the upper dermis.
Blood Vessels ; Dermis ; Fathers ; Humans ; Nevus ; Nuclear Family ; Telangiectasia, Hereditary Hemorrhagic* ; Thorax

No abstract available.
Neck* ; Urinary Bladder* ; Urinary Incontinence*

We described a 65-year-old woman with a papule on the left temple area of } year duration. The lesion showed typical findings of atypical fibroxanthoma and was located on the lesion of solar keratosis, So sunlight may be the most important one among the various insults to atypical fibroxanthoma of the skin.
Aged ; Female ; Humans ; Keratosis ; Skin ; Sunlight

No abstract available.
Bacillus* ; Humans ; Urinary Bladder Neoplasms* ; Urinary Bladder*

PURPOSE: We evaluated the effects of amitriptyline in patients with urinary frequency or pelvic pain syndrome and compared with propiverine hydrochloride (BUP-4(R)) and diazepam (Valium(R)). MATERIALS AND METHODS: One-hundred and sixty-eight patients with urinary frequency or pain were included and 38 out of 168 patients were lost to follow up. The patients with interstitial cystitis, UTI and neurogenic bladder were excluded. Amitriptyline group were instructed to take 25mg to 75mg of amitriptyline before bed. Propiverine hy drochloride and diazepam group were instructed to take 20mg, 4-6mg before bed, respectively. The clinical effects and side effects were evaluated after 4 weeks of medication. RESULTS: In the amitriptyline group, 73.1% in 78 patients with frequency, 68.3% in 60 pain, 65.6% in 32 nocturia, 53.8% in 26 weak urinary stream, 53.8% in 13 dysuria, 72.7% in 11 urgency showed symptom improvement. Urinary frequency and pain score were significantly decreased in the amitriptyline group. In the propiverine hydrochloride group, 66.7% in 21 patients with frequency, 38.8% in 18 pain showed symptom improvement. In the diazepam group, 37.5% in 24 patients with frequency, 31.3% in 16 pain showed symptom improvement. Side effects of amitriptyline had appeared in 24 (27.6%) out of 87 patients; 17 cases of dry mouth, 10 drowsiness, 2 agitation, 2 nausea, 1 constipation and 1 skin rash. CONCLUSIONS: Amitriptyline is useful in vague voiding symptoms especially in urinary frequency and chronic pelvic pain syndrome. It is equally effective in both men and women. Side effects are minimal and tolerable. A double-blind placebo-controlled trial is necessary for general acceptance in the future.
Amitriptyline* ; Constipation ; Cystitis, Interstitial ; Diazepam ; Dihydroergotamine ; Dysuria ; Exanthema ; Female ; Humans ; Lost to Follow-Up ; Male ; Mouth ; Nausea ; Nocturia ; Pelvic Pain* ; Rivers ; Sleep Stages ; Urinary Bladder, Neurogenic

No abstract available.
Busan* ; Cytogenetics*

Retroperitoneum is often the site of occurrence of schwannoma, but reports on schwanoma of the adrenal gland is exceptional and only 4 cases have been documented in the literature. This report is to add one such case occurred in a 53 year-old male who had anorexia, nausea and indigestion for one month. Whole body bone scan and abdominal CT scan revealed a 10 cm sized solid mass at upper pole of the left kidney. Under the impression of renal cell carcinoma, an operation was performed. The tumor was well encapsulated and appeared not to involve the kidney. The cut surfaces were light yellow and seemed to be composed of several hard lobules with areas of mucoid, cystic and calcific changes. No adrenal gland was identified grossly. But microscopically, the tumor was found to be partly surrounded by a small portion of adrenal cortical tissue. Histologically the tumor was a typical schwannoma with Verocay bodies, although modified in some extents by mucoid degeneration, cystic change, hyaline change and focal calcification. It is worthwhile to remember that the retroperitoneal schwannoma commonly had a huge size, sometimes involving the adjacent structures.
Male ; Humans

No abstract available.
Humans ; Prednisolone* ; Prostate* ; Prostatic Neoplasms*

No abstract available.
Skin* ; Spinal Cord Injuries* ; Spinal Cord*

The majority of injections intended to be intramuscular are actually delivered into fat in the area of thebuttock in most of the patients having a thick gluteal fat layer. Injections of some drugs can cause tissuenecrosis that ensues in scar formation and often in dystrophic calcifiation giving rise to ring-like densities inantero-posterior radiographs of the pelvis. We studied the incidence and characteristics of calcifications in thebuttocks frequently noted in pelvic radiographs and whether they have any relationship with thickness anddistribution pattern of the fat layer in the buttocks. Pelvic radiograms of 220 consecutive patients (110 malesand 110 females) with the age ranging from 16 to 76 years(average 39) were reviewed. The area of buttock was divided arbitrarily into four quadrants by the vertical line crossing the center of the head of each femur and thehorizontal line connecting the summit of each femoral head, and the upper outer quadrant was further divided into four quadrants(Fig. 1). We measured the thickness of the extraperitoneal fat layer at the level where it cross theiliac crest bilaterally. The results were as follows; 1. Thirty out of 220 cases(14%) showed calcifications in thebuttock. 2. Calcifications in the buttock were much more frequent in female than in male (p<0.01). 3. Theincidence of calcifications increased with age(P<0.01) and with increase in fat layer thickness(P<0.01). 4,Calcifications in the buttock were mostly located at the upper outer quadrant of the buttock (78%). 5. Inconclusion, we assume that calcifications in the buttock are result of fat necrosis after injection into fatinstead of muscle.
Buttocks ; Cicatrix ; Fat Necrosis ; Female ; Femur ; Head ; Humans ; Incidence ; Male ; Pelvis