A case of nevus spilus, treated by, dermabrasion, was presented with discussion about the entity of the nevus. The patient, a 20 years old healthy woman, had had a palm-sized brown macule speckled with multiple darker small spots on the lateral aspect of her letf calf since birth. The pigmented macule was removed successfully by dermabrasion.
Dermabrasion* ; Female ; Humans ; Nevus* ; Parturition ; Young Adult

Clinical, mycoIogical, histopathological and epidemiological studies were done on 26 cases of cutaneous sporotrichosis which were found during the last 5 years, from 1967 to 1971, at the out-patient clinic of department of dermatology of this hospital, and the results obtained were as follows: 1. Twenty two cases of ascending lympho-cutaneous sporotrichosis with nodules, abscesses and chancres, 2 cases of gummatous, and one of each verrucoid and impctiginous types were found in total 26 cases of the disease. 2. All the patients encountered were inhabitants in rural area, and most of them were farmers (21 cases: 81%)and children living in that area. The sources of the infection were considered as soil and plants contaminated with the causative organism. 3. Age distribution of the disease revealed highest incidence in the fourth and fifth decades (l8 cases: 69%), who were active workers in Korean farm.4. Analysis of primary focus and affected region of the body revealed highest involvement over the upper extremities (19 cases: 73%), especially right hand (9 cases: 35%) and right arm (3 cases: 12%). 5. Better culture results were obtained as following order: the best with culture material aspirated from the closed abscess with sterile needIe and syringe, the second: with embeding the tissue from the lesion in the media exposing about half, and the third: with the materials obtained from the chancre and gumrnatous lesiors. 6. Histopathological findings revealed frequently the chronic inflammatory granulomatous tissue reaction with polymorphic cellularity and occasionally some vascularity or small multiple focal necrosis in the lesions. 7. Differential diagnosis of the disease should be considered with Lepromatous leprosy, Cysticercosis cutis, Tuberculosis of the skin and other mycobacteriosis of the skin particularly in this country. 8. In Korea the rate of the incidences of the disease was found to be the highest in Chonnam province by comparing the result obtained from this study with those of the report by others. In Chonnam province the disease were distributed almost all the counties but there were some different rates of the incidence of the disease between each counties. 9. Frequency of the disease among the total number of out-patients (12. 208) was 0.2% or 1 to 500 and showed relatively high incidence of the disease in the farm workers in Chonnam province, Korea. Clinical, mycoIogical, histopathological and epidemiological studies were done on 26 cases of cutaneous sporotrichosis which were found during the last 5 years, from 1967 to 1971, at the out-patient clinic of department of dermatology of this hospital, and the results obtained were as follows: 1. Twenty two cases of ascending lympho-cutaneous sporotrichosis with nodules, abscesses and chancres, 2 cases of gummatous, and one of each verrucoid and impctiginous types were found in total 26 cases of the disease. 2. All the patients encountered were inhabitants in rural area, and most of them were farmers (21 cases: 81%)and children living in that area. The sources of the infection were considered as soil and plants contaminated with the causative organism. 3. Age distribution of the disease revealed highest incidence in the fourth and fifth decades (l8 cases: 69%), who were active workers in Korean farm.4. Analysis of primary focus and affected region of the body revealed highest involvement over the upper extremities (19 cases: 73%), especially right hand (9 cases: 35%) and right arm (3 cases: 12%). 5. Better culture results were obtained as following order: the best with culture material aspirated from the closed abscess with sterile needIe and syringe, the second: with embeding the tissue from the lesion in the media exposing about half, and the third: with the materials obtained from the chancre and gumrnatous lesiors. 6. Histopathological findings revealed frequently the chronic inflammatory granulomatous tissue reaction with polymorphic cellularity and occasionally some vascularity or small multiple focal necrosis in the lesions. 7. Differential diagnosis of the disease should be considered with Lepromatous leprosy, Cysticercosis cutis, Tuberculosis of the skin and other mycobacteriosis of the skin particularly in this country. 8. In Korea the rate of the incidences of the disease was found to be the highest in Chonnam province by comparing the result obtained from this study with those of the report by others. In Chonnam province the disease were distributed almost all the counties but there were some different rates of the incidence of the disease between each counties. 9. Frequency of the disease among the total number of out-patients (12. 208) was 0.2% or 1 to 500 and showed relatively high incidence of the disease in the farm workers in Chonnam province, Korea.
Abscess ; Age Distribution ; Arm ; Chancre ; Child ; Cysticercosis ; Dermatology ; Diagnosis, Differential ; Epidemiologic Studies* ; Fisheries* ; Hand ; Humans ; Incidence ; Jeollanam-do ; Korea* ; Leprosy, Lepromatous ; Necrosis ; Outpatients ; Skin ; Soil ; Sporotrichosis* ; Syringes ; Tuberculosis ; Upper Extremity

No abstract available.

BACKGROUND: Androgenetic alopecia (patterned baldness) occurs in both sexes showing different clinical features respectively. In men the hait thinning develops at about 20 years of age with a receding anterior hair line. In women it develops at about 30 years of age but the anterior hair liae is kept intact. Recently we have noticed female pattern baldness in young adult females in their early twenties. OBJECTIVE: The purpose of this study was to evaluate clinical and laboratory features of female patients with early onset patterned alopecia and to assess their therapeutic results. METHOD: Twenty-five cases of female pattern baldness who sought medical treatment for hair thinning before the age of 25 were examined for their clinical, laboratorial and treatment results. RESULTS: 1. 22.2 years was the average age at which the first medical care was sought and their onset of noticeable hair thinning was on average 18.3 years of age. 2. Aceording to Ludwigs classification, there were 76%(19 cases) with type I alopecia and 24%(6 cases) wit type II. Type III was not found. 3. A family history of patterned alopecia was seen in 56% of the first degree relatives. 4. Associated diseases were as follows: Seborrheic dermatitis(11 cases), hirsutism(9 cases), acne vulgaris(5 cases), menstrual irregularity(5 cases) and one case of each of polycystic ovarian disease, diabetes melitus and pulmonary tuberculosis. 5. Mild to moderate hirsutism was seen in 9(36%) cases in various anatomical locations. The most frequent location was in the linea alba area (6 cases), which was followed by the extremities and upper lip. 6. Serum iron and femtin levels were lower than the normal range in 10 cases(40%) and in 15 cases(60%) respectively, though hemoglobin levels were all normal. 7. Serum total testosterone and dehydroepiandrosterone sulfate(DHEAS) levels were increased in 52.1% and 52% patients respectively, compared to the normal range in Korean women. 8. In 12 cases who could be followed up for longer than 3 months, 11(90.2%) cases showed improvement in their hair volume on medical treatment. CONCLUSION: Androgenetic alopecia of females can occur as early as in males. The clinical and laboratory findings of such early female androgenetic alopecia were reported in 25 cases alongside their therapeutic outcomes.
Acne Vulgaris ; Alopecia* ; Classification ; Dehydroepiandrosterone ; Extremities ; Female* ; Hair ; Hirsutism ; Humans ; Iron ; Lip ; Male ; Ovarian Diseases ; Reference Values ; Testosterone ; Tuberculosis, Pulmonary ; Young Adult

Intralesional injection of adrenal corticosteroids has widely teen used in the treatment of alopecia areata. But the concentration of the drug and the intrval of the injection are greatly different among the physicians practicing the method. The author evaluated the therapeutie results and untoward effects of the intralesional injetions using two different concentrations on the same lesion devided into two or on the two simultaneousely occurred lesions in each patient, to make exact comparsion of the different concentrations in total 24 patients. Intralesional injections with triamcinolone acetonide 5mg/m a 2 week interval showed appreciable hair regrowing in 4 weeks in 62.5% while 1mg/ml of the drug at equal interval showed appreciable hair regrowing in 6 weeks in 66.7%. But, in the group of 5mg/ml, 16.7% of the lesions showed considerable delay of the hair growing because of the atropy of the skin and hair follicle while no such delay was found in the group 1mg/ml. With the above data, tlie best result would be expected by th concentration between 1mg/ml and 5mg/ml in case of triarncinolone acetonide intralesional injection at 2 week intervals,
Adolescent ; Adrenal Cortex Hormones ; Alopecia Areata* ; Alopecia* ; Hair ; Hair Follicle ; Humans ; Injections, Intralesional ; Skin ; Triamcinolone Acetonide

Students of alopecia areata (AA) face confusion in the understanding of the follicular status of the lesion. This confusion partly is related to varing histopathological descriptions given by different authors. In an attempt to clarify these varing descriptions, we made our own observations on 45 scalp biopsies from the patients with AA. The lesions were devided into four groups by the duration of the alopecia. The results were as in the following. Initial stage (within 2 weeks after the onset, 5 cases) showed mostly the catagen stage of terminal hair follicles and pigmentary incontinence in all cases. Only 2 cases (40%) showed significant cellular infiltrate. Progressive stage (between 2 weeks and several months after onset, 11 cases) showed catagen follicles of terminal hair with the development of miniature follicles among them. Pigmentary incontinence and inflammatory cell infiltrate were seen in 9 cases (82%) and 8 cases (73%) respectively. In established stage (26 cases), miniature follicles were predominant with pigmentary incontinence (73%: 19 cases) and cellular infiltrate (69%: 18 cases). In recovery stage, there were normal anagen follicles with absent or decreased inflammatory cells and pigmentary incontinence. A proposal that hair follicles better be designated not only with their stages but also with their types is presented.
Alopecia Areata* ; Alopecia* ; Biopsy ; Hair ; Hair Follicle ; Humans ; Scalp

The linear IgA bullous dermatosis is a rare chronic vesicobullous disease resembling dermatitis herpetiformis or bullous pemphigoid. We report a case of linear IgA bullous dermatosis developed in a 16 year old female, whose cutaneous lesions were unusually acute. The urticarial wheals started on her buttock and spread to her entire body in two hours and generalized blistering de veloped within four days, The response by dapsone was also dramatic. Routine histological and both direct and indirect immunofluorescent microscopic findings were typical of linear IgA bullous dermatosis.
Adolescent ; Adult* ; Blister ; Buttocks ; Dapsone ; Dermatitis Herpetiformis ; Female ; Humans ; Linear IgA Bullous Dermatosis* ; Pemphigoid, Bullous

No abstract available.
Addison Disease*

Squamous cell carcinoma developed from the lesion of acne conglobata is very rare and none of the cases reported hitherto showed metastasis. A 42 year-old male with widespread lesions of acne conglobata complicated by giant ulcerative. squamous cell carcinoma on the sacral area is reported. It metastasized to both inguinal lymph nodes. Radiation therapy was tried but the patient died 3.5 years after the development of the carcinoma.
Acne Vulgaris* ; Adult ; Carcinoma, Squamous Cell* ; Humans ; Lymph Nodes ; Male ; Neoplasm Metastasis* ; Ulcer

Bowen's disease is intraepidermal squamous cell carcinoma involving skin and certain mucocutaneous junctions. The disease usually persues a slow relatively benign course but may progress to invasive squamous cell carcinoma. The present case, 67-years-old male, showed multiple dark brownish somewhat elevated horny lesions on the trunk and extremities including both palms. Some of the lesions had the appearance of small horns. Multiple biopsy specimens revealed typical histological findings of Bowen's disease or frank invasive squamous cell carcinoma. according to the each biopsy site. Authors treated all the lesions with surgical avulsion and electrodesiccation with curettage under general anestthesia and subsequent topical 5-FU ointment application.
Animals ; Biopsy ; Bowen's Disease* ; Carcinoma, Squamous Cell* ; Curettage ; Extremities ; Fluorouracil ; Horns* ; Humans ; Male ; Skin