The present report describes a case of VATER syndrome with situs inversus viscerum totalis in a newborn Korean male infant who died immediately after his birth. The disposition of all the organs in thoracic and abdominal cavities formed a complete mirror picture of normal disposition. In addition, the following abnormalities were also present : 1) Unsegmented bar of the 12th thoracic vertebra fused with 11th thoracic vertebra at left side and 1st lumbar vertebra at right side, 2) Imperforated anus (Type 3 of Ladd and Grorss classification), 3) Tracheoesophageal fistula with upper esophageal atresia, 4) Patent ductus arteriosus connected to the descending aorta, 5) Atrial septal defect, septum primum type, 6) Slightly enlarged ureter, 7) Translocation of cecum with appendix beneath the liver, 8) Coiled appendix, 9) Incomplete oblique fissure of the right lung.
Abdominal Cavity ; Anal Canal ; Aorta, Thoracic ; Appendix ; Cecum ; Ductus Arteriosus, Patent ; Esophageal Atresia ; Heart Septal Defects, Atrial ; Humans ; Infant* ; Infant, Newborn* ; Liver ; Lung ; Male* ; Parturition ; Situs Inversus* ; Spine ; Tracheoesophageal Fistula ; Ureter

No Abstract Available.
Amblyopia*

The isomorphic response of Koebner is a well-known phenomenon commonly associated with psoriafsis, but it has been also descrilbed in conjunction with a host of other disordered. We described five cases of erythema multiforme showing lesions of easily recognizsble Koebnei phenomena. Traumas to the skin do not cause erythema multiforme, however when a patient is in an active stage of the disease, physieal factor such as traumas occuring in normsl daly-life may contribute to the distribution of skin lesions as have been seen in our patients ; clinicians should aware of this point for better understanding of clinical features in erythema multiforme.
Erythema Multiforme ; Erythema* ; Humans ; Skin

No abstract available.

BACKGROUND: Several reports have demonstrated that TGFalpha and EGF are mitogenic for keratinocytes. Whenther its expression on epithelial tumors is a marker of malignancy or signifies an important step in the development of neoplasia is poorly understood. EGF receptors are also present in normal epidermis and epithelial tumors but their physiological roles are not yet understood. OBJECTIVE: Our purpose was to examine the staining patterns of TGFalpha, EGF and EGF receptors on the npithelial tumors of the skin, and to investigate kinetics of expression of EGF receptors. METHODS: We performed immunoperoxidase staining(ABC technique) with monoclonal anti-TGFalpha antibody, polyclonal anti-EGF antibody and polyclonal anti-EGF receptor antibody on the formalinfixed, paraffin-embedded tissue specimens of benign, premalignant and malignant skin tumors. RESULTS: The density of the expression of TGFalpha and EGF was not correlated with the degree of the malignancy of the epithelial tumors and is neither constant in any kind of the tumors. However the infiltrative type of basal cell carcinoma(BCC) is stronger that its solid type on the expression of TGFalpha and EGF. All benign tumors demonstrated a diffuse pattern within tumor lobules. pression of TGFalpha and EGF. All benign tumors demonstrated a diffuse pattern within tumor lobules. Focal TGFalpha immunostaining was seen in three of 10 squamous cell carcinomas(SCC) and four of 10 BCCs. TGFalpha immunostaining was absent from the outermost one to two layers of tumor lobules of all keratoacanthomas. The specimens which increased the expression of TGFalpha and EGF tended to decrease the expression of EGF receptor. CONCLUSION: These data suggest that the density of immunohistochemical expression of TGFalpha and EGF may be not dependent on the differentiation of tumor cells, and the pattern of immunohistochemical expression of TGFalpha can differentiate SCC from benign tumors such as keratoacanthoma. FGF receptor may be occupied by both of TGFalpha and EGF. With the receptors being occupied, a down regulation of the receptors may occur which results in decreased EGF receptor expression.
Down-Regulation ; Epidermal Growth Factor* ; Epidermis ; Keratinocytes ; Keratoacanthoma ; Kinetics ; Receptor, Epidermal Growth Factor* ; Receptors, Fibroblast Growth Factor ; Skin* ; Transforming Growth Factor alpha*

The purpose of this study was to investigate the root resorption pattern in incisors in dog under intrusive orthodontic loadings of various magnitude and duration. Intrusive forces were generated by closed coil springs. Force magnitudes were 15-30gm, 50-60gm and 80-110gm. Durations were continuous and intermittent. Intermittent duration was applied at intervals of 12 hours. The readjustment of the force was done every 4 days. The forces were maintained for 30 days. All specimens were decalfied, embedded in paraffin and stained with hematoxylin-eosin stain. Observations were made with light microscope. The following results were obtained; 1. The continuity of root surface was ceased in all, except intermittent forced teeth with 25gm. 2. The root resorptions, cementoclasts and cemental lacunae, were increased around periapical regions and the destructive scope of bone was deeply extended as the exerted orthodontic forces increased. 3. It was inspected that, under the same forces, root resorption and bone destruction were more deeply appeared in the continuously forced teeth than the intermittently forced ones. 4. All of the alveolar bone, showed direct and undermining bone resorptions.
Animals ; Bone Resorption ; Dogs* ; Incisor* ; Osteoclasts ; Paraffin ; Root Resorption* ; Tooth

No abstract available.
Arthrography*

Injuries are serious problem common to all societies. Yet even within a single community, groups of injured persons differ as to the nature and severity of their injuries. The difficulty of adjusting for such variations has hampered scientific study of injured persons. Neverthless it is essential to take differences in severity of injury into account when comparing the morhidity & mortality of various groups for the purpose of evaluating their emergency & subsequent care. In order to provide the guidelines of mass emergency care & transportation, the authors analysed the 206 injured patients of train accident at Kyungsan, May 14th, 1981 and compared mortality with severity and body system of the injuries. The results were obtained as follows: l. Of 206 injured patients, most were young people & the ratio of male & female was about equal. 2. Extremities were the most frequently injured parts of body system & single injury was more common. 3. According to most severe injury of AIS, 78% of injured persons belonged to below AIS grade 3 and none was dead. 4. Average ISS of survival groups was 6 and that of death groups was 34. None was dead below average ISS of 15. 5. Death rate was higher for patients above 50 years of age, than that for young patients and there was no age difference in mortality for ISS of 50 and higher. 6. Majority of death group were invclved in multiple injuries and major cause of death were chest and head injuries. 7. Average ISS and age of hospital death group were less than those of DOA group. 8. The authors thought that it was necessary to estahlish Emergency Service System including training and education of both professionals and the pulic, hospital categorization, communication and transportation system for the mass emergency care.
Cause of Death ; Craniocerebral Trauma ; Education ; Emergencies ; Emergency Medical Services ; Extremities ; Female ; Gyeongsangbuk-do ; Humans ; Injury Severity Score ; Male ; Mass Casualty Incidents ; Mortality ; Multiple Trauma ; Thorax ; Transportation

No abstract available.
Sterilization, Tubal*

PURPOSE: Plasma fibronectin is thought to have important role in the inflammatory response and host defense. We performed this study to evaluate concentration in the full-term, healthy preterm, asphyxia and respiratory distress syndrome and how that correlated with gestational age and birth weight. METHODS: We evaluate 51 neonates who were delivered at Korea University Hospital from Jan. 1992 to Jul. 1992. In order to evaluate concentration of plasma fibronectin according to gestational age and birth weight in 51 neonates, we measured plasma fibronectin in healthy premature and term infants and investigated the alteration in plasma values in infants with perinatal asphyxia and respiratory distress syndrome. RESULTS: 1) The concentration of plasma fibronectin was lower in preterm infants(123+/-30ug/dl) than in term infants(151+/-26ug/dl). 2) There was a significant correlation between the plasma fibronectin concentration and both gestational age and weight (p<0.01). 3) The infant with perinatal asphyxia and respiratory distress syndrome had lower plasma fibronectin concentration than those in age matched healthy infant. CONCLUSIONS: This results shows that the plasma fibronectin correlate with gestational age and birth weight and suggests that deficiency of plasma fibronectin correlate with reticuloendothelial system hypofunction in infants with complicated birth.
Asphyxia ; Birth Weight ; Fibronectins* ; Gestational Age ; Humans ; Infant ; Infant, Newborn* ; Korea ; Mononuclear Phagocyte System ; Parturition ; Plasma*