1.A study of care for diabetic patients in primary care setting.
Chang Hun CHOI ; Kyeung Yul KIM ; Chul Yung BAE ; Hang Soon SHIN ; Dong Hak SHIN
Journal of the Korean Academy of Family Medicine 1993;14(4):258-264
No abstract available.
Humans
;
Primary Health Care*
2.Total Knee Replacement in Gonarthrosis
Dae Kyung BAE ; Myung Chul YOO ; Song LEE ; Yung Yong KIM
The Journal of the Korean Orthopaedic Association 1986;21(5):915-922
We studied the results in forty-three knees in thirty patients-three male and twenty seven femalewho had rheumatoid arthritis, osteoarthritis, traumatic arthritis and osteonecrosis in the knee and were treated by total knee joint replacement. The average age of the patients was 56.7 years. The results were anaysed after follow-ups ranging from one year to three years and seven months, average being 23.6 months. The assessment was made upon the knee rating system of the Hospital for Special Surgery; the results were excellent in 29 knees, good in 12, fair in one and poor in one. The improvement of the flexion contractures was significant (postoperative average 1.7 degrees compared with preoperative average 20.1 degrees). The postoperative active flexion ranged from 70 degrees to 140 degrees (mean 110.2 degrees). One knee had a deep wound infection. The radiological loosening demonstrated in three cases, two of them had incomplete, nonprogressive radiolucent line, being less than one millimeter in width in the tibial component, one who had a deep infection showed three millimeters radiolucent line.
Arthritis
;
Arthritis, Rheumatoid
;
Arthroplasty
;
Arthroplasty, Replacement, Knee
;
Contracture
;
Follow-Up Studies
;
Humans
;
Knee
;
Knee Joint
;
Male
;
Osteoarthritis
;
Osteonecrosis
;
Wound Infection
3.A case of staphylococcal myocaridtis with complete atrioventricular block.
Ho Chul SONG ; Kee Bae SEUNG ; Jong Soon RAH ; Kyo Yung CHOO ; Won Yung LEE ; Dong Hun KANG ; Kyoo Bo CHOI ; Moon Won KANG
Korean Journal of Infectious Diseases 1993;25(4):383-386
No abstract available.
Atrioventricular Block*
4.The Application and Effect of the Brown-Roberts-Wells Stereotactic System in the Management of Intracranial Lesions.
Choong Bae MOON ; Wan Shup KIM ; Sam Kyu KO ; Jowa Hyuk IHM ; Seung Chan BAEK ; Yung Chul CHI ; Byung Yearn CHOI ; Soo Ho CHO
Yeungnam University Journal of Medicine 1986;3(1):53-62
In the past 10 years, modern technology has made deep seated obscure lesions visible. With development of computer technology and various stereotaxic techniques, many new procedures, refinement of old procedures, and development of new applications are possible. The authors are intended to provide a detailed description of our experience with the Brown-Roberts-Wells (BRW) stereotactic system in the evaluation and management of 90 patients with intracranial lesions, and to provide cases presentation of various inaccessible intracranial lesions.
Humans
;
Stereotaxic Techniques
5.The clinical usefulness of cardiac troponin I as a marker for severity in patients with congestive heart failure.
Hyeon Gook LEE ; Woo Hyung BAE ; Seong Ho KIM ; Byung Jae AN ; Kook Jin CHUN ; Taek Jong HONG ; Byung Mann JO ; Han Chul SON ; Yung Woo SHIN
Korean Circulation Journal 2000;30(6):724-728
BACKGROUND AND OBJECTIVES: Spontaneous progression of severe congestive heart failure is structurally characterized by cellular degeneration and multiple foci of myocardial cell death. The cardiac troponin I (cTnI), one of the subunits of the troponin regulatory complex, binds to actin and inhibits interaction between actin and myosin. cTnI is uniquely expressed in the adult human myocardium, and an increase in its circulating levels is highly indicative of myocardial injury. In this study, we addressed the usefulness of cTnI as a sensitive and specific molecular marker for severity in patients with congestive heart failure. MethodscTnI, creatinin kinase-MB (CK-MB), and myoglobin were assessed in 59 patients with severe congestive heart failure diagnosed by the echo-cardiography and gated equilibrium blood pool heart scan. Also we assesed cTnI, creatinin kinase-MB (CK-MB), and myoglobin in 25 persons without cardiac disease in echocardiography. RESULTS: 1) The cTnI con-centration was 89.6+/-69.3 pg/mL in patients with congestive heart failure and its level was greater than that of the control group (22.4+/-17.1, p=0.001). 2) The cTnI level differed significantly according to left ventricular ejection fraction (EF), 117.3+/-73.8 pg/mL in patients with EF\<40% (28 patients), 66.3+/-44.5 pg/mL in patients with EF> or =40% (31 patients), 22.4+/-17.1 pg/mL in the control group (25 persons) (p=0.001). CONCLUSION: cTnI was useful as a specific and sensitive serum molecular marker in patients of congestive heart failure. And its level reflected the severity of congestive heart failure.
Actins
;
Adult
;
Cell Death
;
Echocardiography
;
Equidae
;
Estrogens, Conjugated (USP)*
;
Heart
;
Heart Diseases
;
Heart Failure*
;
Humans
;
Myocardium
;
Myoglobin
;
Myosins
;
Stroke Volume
;
Troponin I*
;
Troponin*
6.A study of geriatric inpatients.
Seon Wook KANG ; Kyung Min HAN ; Kyeong Yeol KIM ; Chang Hoon CHOI ; Eun Su KU ; Chul Yung BAE ; Dong Hak SHIN
Journal of the Korean Academy of Family Medicine 1993;14(11):715-724
No abstract available.
Humans
;
Inpatients*
7.A Case of Klippel-Trenaunay Syndrome with Acute Submassive Pulmonary Thromboembolism Treated with Thrombolytic Therapy.
Seong Taek CHU ; Yung Hee HAN ; Jung A KOH ; Seon Jae KIM ; Hak Cheol LEE ; Si Eun KIM ; Yong Chul SHIN ; Jung Ju SIR ; Seung Min CHOI ; Shin Bae JOO
Journal of Cardiovascular Ultrasound 2015;23(4):266-270
Klippel-Trenaunay syndrome is a rare congenital mesodermal abnormality characterized by varicose veins, cutaneous hemangiomas, soft tissue and bony hypertrophy of limb. Potential complications such as deep venous thrombosis and pulmonary thromboembolism have not been reported in Korea to date. We demonstrate the case of a 48-year-old woman with Klippel-Trenaunay syndrome with extensive varicose veins on right lower limb, hypertrophy of left big toe and basilar artery tip aneurysm, complicated with acute submassive pulmonary thromboembolism treated successfully with intravenous thrombolytic therapy.
Aneurysm
;
Basilar Artery
;
Extremities
;
Female
;
Heart Failure
;
Hemangioma
;
Humans
;
Hypertrophy
;
Intracranial Aneurysm
;
Klippel-Trenaunay-Weber Syndrome*
;
Korea
;
Lower Extremity
;
Mesoderm
;
Middle Aged
;
Pulmonary Embolism*
;
Thrombolytic Therapy*
;
Toes
;
Varicose Veins
;
Venous Thromboembolism
;
Venous Thrombosis
8.Conventional Treatments in Patients with Hodgkin's Disease.
Jong Beom PARK ; Chul Won SEO ; Sang Hee KIM ; Kyung No LEE ; Hun Ho SONG ; Soon Seo PARK ; Hyo Jung KIM ; Yung Joo MIN ; Jin Hee PARK ; Sung Joon CHOE ; Jung Koon KIM ; Tae Won KIM ; Dae Yung JANG ; Je Hwan LEE ; Sung Bae KIM ; Sang Wee KIM ; Koo Hyung LEE ; Jung Sin LEE ; Woo Keon KIM
Journal of the Korean Cancer Association 1999;31(4):821-829
PURPOSE: We conducted this study to determine the efficacy of conventional treatments for patients with Hodgkin's disease and identify the patients who have poor prognosis and need high-dose chemotherapy and autologous stem cell transplantation. MATERIALS AND METHODS: Between Jun. 1989 and Dec. 1997, 50 patients were enrolled and 39 patients were evaluable. Patients were treated with radiotherapy (5 patients) or combination chemotherapy (21 patients) or combined chemotherapy and radiotherapy (13 patients) according to their disease stage. Chemotherapy regimens were C-MOPP (cyclo- phosphamide, vincristine, procarbazine, and prednisone), MOPP (mechlorethamine, vin- cristine, procarbazine, and prednisone), ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine), alternating C-MOPP/ABVD, and MOPP/ABV hybrid. Radiation therapy was performed when there was residual tumor after chemotherapy or bulky disease. The response to treatments was analyzed by clinical stage I-II and stage III-IV patients group, respectively. RESULTS: The complete response rate was 76.9% for total patients, 83.3% for stage I-II patients, and 71.4% for stage III-IV patients. Of the 30 patients achieving complete response, four (13.3%) relapsed at 6, 12, 22, and 28 months after complete response, respectively. The median follow-up duration was 24 months. Nine patients died. Four patients died of Hodgkins disease. Three-year overall survival rate was 72.9% for total patients, 72.5% for stage I-II patients, and 70% for stage III-IV patients. Two-year disease- free survival rate was 77.6% for total patients, 79% for stage I-II stage patients, and 73.9% for stage III-IV patients. The prognostic factor analysis showed that performance status affected the disease-free survival rate. CONCLUSION: Conventional treatments in patients with Hodgkins disease showed results comparable to previous studies. But we were unable to identify the patients, who need high-dose chemotherapy and autologous stem cell transplantation, because of small number of study patients and short follow up duration.
Bleomycin
;
Dimethoate
;
Disease-Free Survival
;
Drug Therapy
;
Drug Therapy, Combination
;
Follow-Up Studies
;
Hodgkin Disease*
;
Humans
;
Neoplasm, Residual
;
Procarbazine
;
Prognosis
;
Radiotherapy
;
Stem Cell Transplantation
;
Survival Rate
;
Vinblastine
;
Vincristine
9.Adult-to-Adult Living Donor Liver Transplantation.
Sung Gyu LEE ; Young Joo LEE ; Kwang Min PARK ; Hoon Bae JEON ; Shin HWANG ; Kang Hong LEE ; Rang Kee LEE ; Jung Joon LEE ; Jae Han JUNG ; Won Yong CHOI ; Jin Wook CHOI ; Chul Soo AHN ; Tae Yong HA ; Hoe Jung JUNG ; Byung Chan LEE ; Kyung Suck KOH ; Sang Hoon PARK ; Kyu Taek CHOI ; Yung Sang LEE ; Young Hwa CHUNG ; Dong Jin SUH ; Myung Hwan KIM ; Moon Gyu LEE ; Kyu Bo SUNG ; Mi Kyong KIM ; Hea Seon HA ; Pyung Chul MIN
Journal of the Korean Surgical Society 1998;55(5):719-725
BACKGROUNDS: Living-donor liver transplantation (LDLT) has been established as an efficacious option to resolve the shortage of cadaveric donor organs for pediatric recipients. This surgical innovation has significantly reduced the pretransplantation mortality for children, but the crisis of increasing scarcity of donor organs in our hospital has led us to extend LDLT to adult recipients. However, the extension of LDLT from pediatric recipients to adult recipients has been made only with limited success largely because of the inability of a relatively small-size left-lobe graft to meet the metabolic demands of an adult recipient. It has been postulated that a left-lobe graft smaller than 40% of the recipient's standard liver volume will not result in a successful adult-to-adult LDLT in chronic parenchymal liver disease. METHODS: From February 1997 to October 1997, 10 LDLTs, using 9 extended left-lobe grafts and 1 right-lobe graft, were performed on patients with end-stage parenchymal liver diseases (9 cases of B-hepatitis-induced cirrhosis with or without an associated hepatocellular carcinoma and 1 case of alcoholic cirrhosis) at the Department of Surgery, Asan Medical Center. The ratios of the graft to the standard liver volume of the recipients were in the range of 30% to 55%. RESULTS: All grafts showed immediate function, but delayed normalization of the serum total bilirubin was demonstrated in all recipients receiving left-lobe grafts. There were no mortalities and serious complications in donors. Two recipients died of sepsis 21 days and 40 days after transplantation, and 8 recipients (80%) are alive with good liver function at a median follow-up of 5.1 months (range 2~10 months). CONCLUSIONS: The aim of this article is to report our experience with adult-to-adult LDLT shows that a graft size greater than 30% of the recipient's standard liver volume is able to meet the metabolic demands of adult recipients with chronic parenchymal liver disease and that LDLT might open a new donor pool for adult recipients when the supply of cadaveric organs is severely restricted.
Adult
;
Alcoholics
;
Bilirubin
;
Cadaver
;
Carcinoma, Hepatocellular
;
Child
;
Chungcheongnam-do
;
Fibrosis
;
Follow-Up Studies
;
Humans
;
Liver Diseases
;
Liver Transplantation*
;
Liver*
;
Living Donors*
;
Mortality
;
Sepsis
;
Tissue Donors
;
Transplants
10.Safety and Efficacy of Intravenous Thrombolysis in the 3- to 4.5-hour Window in Acute Ischemic Stroke Patients Who Have Both Diabetes Mellitus and History of Prior Stroke
Boyoung KIM ; Ji Sung LEE ; Hong-Kyun PARK ; Young Bok YUNG ; Ki Chang OH ; Jeong Joo PARK ; Yong-Jin CHO ; Kyusik KANG ; Soo Joo LEE ; Jae Guk KIM ; Jae-Kwan CHA ; Dae-Hyun KIM ; Hee-Joon BAE ; Tai Hwan PARK ; Sang-Soon PARK ; Kyung Bok LEE ; Jun LEE ; Byung-Chul LEE ; Minwoo LEE ; Joon-Tae KIM ; Kang-Ho CHOI ; Dong-Eog KIM ; Jay Chol CHOI ; Dong-Ick SHIN ; Jee-Hyun KWON ; Wook-Joo KIM ; Sung Il SOHN ; Jeong-Ho HONG ; Hyung Jong PARK ; Seong-Hwa JANG ; Kwang-Yeol PARK ; Sang-Hwa LEE ; Jong-Moo PARK ; Keun-Sik HONG
Journal of the Korean Neurological Association 2023;41(2):112-120
Background:
For acute ischemic stroke (AIS) patients with history of prior stroke (PS) and diabetes mellitus (DM), intravenous recombinant tissue plasminogen activator (IV-tPA) therapy in the 3- to 4.5-hour window is off-label in Korea. This study aimed to assess the safety and efficacy of IV-tPA in these patients.
Methods:
Using data from a prospective multicenter stroke registry between January 2009 and March 2021, we identified AIS patients who received IV-tPA in the 3- to 4.5-hour window, and compared the outcomes of symptomatic intracranial hemorrhage (SICH), 3-month mortality, 3-month modified Rankin Scale (mRS) score 0-1 and 3-month mRS distribution between patients with both PS and DM (PS/DM, n=56) versus those with neither PS nor DM, or with only one (non-PS/DM, n=927).
Results:
The PS/DM group versus the non-PS/DM group was more likely to have a prior disability, hypertension, hyperlipidemia, coronary heart disease and less likely to have atrial fibrillation. The PS/DM and the non-PS/DM groups had comparable rates of SICH (0% vs. 1.7%; p>0.999) and 3-month mortality (10.7% vs. 10.2%; p=0.9112). The rate of 3-month mRS 0-1 was non-significantly lower in the PS/DM group than in the non-PS/DM group (30.4% vs. 40.7%; adjusted odds ratio [95% confidence interval], 0.81 [0.41-1.59]).
Conclusions
In the 3- to 4.5-hour window, AIS patients with PS/DM, as compared to those with non-PS/DM, might benefit less from IV-tPA. However, given the similar risks of SICH and mortality, IV-tPA in the late time window could be considered in patients with both PS and DM.