The paratertiary butylphenol formaldehyde resin (PTBP-FR) is commonly used as a shoe adhesives because it sticks rapidly, is durable and pliable, and maintains good bond strength at raised temperature. We report two cases of allergic contact dermatitis due to PTBP-FR-containing shoes. Two women visited our department because of the skin rash on their .
Adhesives ; Dermatitis, Allergic Contact* ; Exanthema ; Female ; Formaldehyde* ; Humans ; Shoes*

No abstract available.
Heart* ; Thoracic Surgery*

No abstract available.
Humans* ; Keratinocytes* ; Minoxidil*

No abstract available.
Abscess*

No abstract available.
Adult* ; Humans ; Neck*

No abstract available.
Alleles* ; Humans

Moyamoya disease is characterized by progressive cerebrovascular occlusion at the peripheral internal carotid artery and development of abnormal collateral circulation at the cerebral basal region. Although abnormal thrombogenesis, inflammation and autoimmune process might be involved in the etiology, the genetic pathogenesis of Moyamoya disease is still unknown. To evaluate the association of Moyamoya disease with HLA alleles in the Korean population, we investigated HLA class I and class II alleles in 28 Moyamoya patients and 198 unrelated healthy controls. The frequency of HLA-B35 allele was significantly increased in the patients compared to the controls (32.1% vs. 10.1%, RR=4.2, p<0.008). Further analysis of HLA-B35 on onset age and sex showed that this allele was significantly increased compared to the controls in both late-onset and female group. Especially, HLA-B35 was the most significantly increased in female of late-onset group compared to the controls. These results suggest that HLA-B35 may be an useful genetic marker for Moyamoya disease, and particularly in females of late onset group in the Korean population.
Adolescent ; Adult ; Age of Onset ; Aged ; Child ; Child, Preschool ; Female ; Gene Frequency ; *Genes, MHC Class I ; *Genes, MHC Class II ; Genetic Markers ; Genetic Predisposition to Disease ; Genotype ; HLA Antigens/*genetics ; Human ; Korea ; Male ; Middle Aged ; Moyamoya Disease/*genetics/*immunology ; Retrospective Studies ; Support, Non-U.S. Gov't

212 cases of hypertensive intracerebral hematoma were treated and followed for more than 3 months. The outcome was analysed in point of comparison between conservative treatment and operative treatment. The precipitating factors on prognosis depend on size and site of hematoma, level of mental deterioration, and blood pressure on admisson. Operative treatment showed better outcome than conservative treatment in cases of severly mentally deteriorated patients, large hematoma, and pontine hematoma.
Blood Pressure ; Hematoma* ; Humans ; Precipitating Factors ; Prognosis

A prospective analysis of 106 patients with head injury whose initial Glasgow Coma Scale was 3 to 10, who were managed in a uniform way was analyzed to relate out come to initial Glasgow Coma Scale, combined injuries and secondary systemic insults characterized by serum electrolytes imbalance, arterial gas study, blood pressure, and hemoglobin and hematocrit. The good recovery or moderate disability were achieved by 37% of the patients. The remaining 63% resulted in severe disability, vegetable and death. The poor out come group in comparing with the good outcome group showed lower initial Glasgow Coma Scale and more combined injuries. The five week follow up of secondary systemic insults mean flow showed higher serum Na flow and lower arterial PaO2 flow in poor outcome group.
Blood Pressure ; Craniocerebral Trauma ; Electrolytes ; Follow-Up Studies ; Glasgow Coma Scale* ; Glasgow Outcome Scale ; Head* ; Hematocrit ; Humans ; Prospective Studies ; Vegetables

BACKGROUND: Psoriasis is an inflammatory skin disorder that is characterized by a marked proliferation of keratinocytes, vascular dilation and leukocyte infiltration. Cytokines play important roles in the pathogenesis of inflammatory disorders. An overexpression of proinflammatory cytokines was characterized in psoriasis plaque. Among these cytokines, IL-1beta is major pro-inflammatory cytokine synthesized during the infection and inflammatory process. The IL-1 receptor antagonist (IL-1Ra) competes for the same IL-1 receptor for IL-1alpha and -1beta, which prevents activation of the target cells. Three single nucleotide polymorphisms (SNPs) in the IL-1beta gene have been reported at position-31, -511 and +3954. Within the IL-1Ra gene (IL-1RN), there is a variable number of tandem repeats (VNTR) of an 86 bp length in intron 2. These polymorphisms related to cytokine production and associated with various diseases. METHODS: We investigated the polymorphisms of IL-1B (promoter -511 and +3954) and IL-1RN on 114 psoriasis patients and -311 healthy normal controls in Korean. We performed PCR-RFLP on single nucleotide polymorphisms (SNPs) of IL-1B (promoter -511 and +3954) and fragment analysis on IL-1RN 86 bp VNTR polymorphism. RESULTS: The frequency of IL-1B-511*1 allele (patients vs. controls; 50.0% vs. 42.3%, RR=1.4) was significantly increased and IL-1B -511*2 allele (patients vs. controls; 50.0% vs. 57.7%, RR=0.7) decreased in psoriasis patients compared to normal controls. We also analyzed the IL-1B -511 polymorphism according to patients' characters (age of onset, sex and family history). The IL-1B -511 alleles were significantly associated in patients with male and family history than health normal controls. There were no significant associations of IL-1B +3954 and IL-1RN polymorphisms with psoriasis patients. CONCLUSION: These results suggest that the polymorphism of IL-1B -511 could be genetic susceptibility to psoriasis in Koreans.
Alleles ; Cytokines ; Genetic Predisposition to Disease ; Humans ; Interleukin 1 Receptor Antagonist Protein ; Interleukin-1 ; Introns ; Keratinocytes ; Leukocytes ; Male ; Minisatellite Repeats ; Polymorphism, Single Nucleotide ; Psoriasis* ; Skin