2.A Case of Tsutsugamushi Disease.
Chul Ho YOO ; Seung Hun LEE ; Jeon Han PARK ; Soo Il CHUN
Korean Journal of Dermatology 1989;27(2):206-210
Tsutsugamushi disease, an infectious disease by Rickettsia(R.) tsntsugamushi, is characterized by eschar, fever and rash. Eschar caused by chigger bite, is pre sent on 47 94% of patients with documented R. tsutsugamushi. We recently noticed one case of R. tsutsugamushi infection. Patient had fever, heaclache, lymphadenopathy, erythematous maculopapules and eschar. The R. tsu tsugamushi was isolated from serum of the patient. Histopathologic findings of eschar show epidermal ulceration overlying a zone of coagulative necrosis of upper dermis and necrotizing vasculitis. E]ectron microscopic findings of endothelial cells of capillary show rickettsia with cell division.
Capillaries
;
Cell Division
;
Communicable Diseases
;
Dermis
;
Endothelial Cells
;
Exanthema
;
Fever
;
Humans
;
Lymphatic Diseases
;
Necrosis
;
Rickettsia
;
Scrub Typhus*
;
Trombiculidae
;
Ulcer
;
Vasculitis
3.Effects of sex hormones on the induction of glutathione S-transferase-P positive hyperplastic hepatic nodules in rats.
Sang Jeon LEE ; Soo Tae KIM ; Sang Chul PARK ; Kye Yong SONG
Journal of the Korean Cancer Association 1991;23(4):708-722
No abstract available.
Animals
;
Glutathione*
;
Gonadal Steroid Hormones*
;
Rats*
4.Fine Needle Aspiration Biopsy of the Lung in Children with Diffuse Pulmonary Lesions Suggesting Pneurnocystis carinii Pneumonia.
Yo Won CHOI ; Yong Soo KIM ; Seok Chol JEON ; Chang Kok HAHM ; Chul Seung CHOI
Journal of the Korean Radiological Society 1994;30(6):1147-1150
PURPOSE: The purpose of this study was to determine the following:the safety of fine needle aspiration biopsy in immunocompromized children with radiographic features of Pneumocystis car/nil pneumonia, its diagnostic rate in those groups and the appropriate radiographic stage for fine needle aspiration biopsy to prove the etiologic agent. METHODS AND MATERIALS: We retrospectively reviewed the patient records of 16 children with immune compromizing diseases who had undergone fine needle aspiration biopsy of the lung. They showed the infectious sign of the lung along with the radiographic pattern of diffuse pulmonary disease, suggesting Pneumocystis carlnil pneumonia. All patients had underlying lymphoreticular malignancies including 14 acute lymphocytic leukemia and 2 non Hodgkin's lymphoma. According to the radiographic pattern of biopsy site, parenchymal disease was categorized as fine reticulonodular density(n=4), ground-glass opacity(n=9) and compact consolidation(n=3). We assessed the diagnostic rate of Pneumocystis carinii pneumonia and complications in each of the three groups. RESULTS: A diagnosis of Pneumocystis carinii pneumonia was established by fine needle aspiration biopsy in 9 patients(56%) including 2 of 4 patients with fine reticulonodular density, 4 of 9 patients with ground-glass opacity, and all 3 patients with compact consolidation. Four patients(25%) developed pneumothorax, and three of them required tube insertion. There was no patient who developed hemoptysis. CONCLUSION: Fine needle aspiration biopsy is a safe and easy method that can yield Pneumocystis carinii organism at a relatively high rate in immunocompromized children with diffuse pulmonary lesions suopicions of Pneumocystis carinii pneumonia. We recommend performing fine needle aspiration biopsy regardlesss of radiographic patterns when Pneumocystis carinii pneumonia is suggested.
Biopsy*
;
Biopsy, Fine-Needle*
;
Child*
;
Diagnosis
;
Hemoptysis
;
Humans
;
Lung Diseases
;
Lung*
;
Lymphoma, Non-Hodgkin
;
Pneumocystis
;
Pneumocystis carinii
;
Pneumonia*
;
Pneumonia, Pneumocystis
;
Pneumothorax
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma
;
Retrospective Studies
5.Treatment of Tracheobronchial Stenosis with a Self-Expandable Metallic Stents.
Yo Won CHOI ; Yong Soo KIM ; Seok Chol JEON ; Chang Kok HAHM ; Chul Seung CHOI
Journal of the Korean Radiological Society 1994;31(1):35-41
PURPOSE: We analysed the role of modified Gianturco self-expandable stents in the treatment of tracheobronchial stenosis in 13 patients. MATERIALS AND METHODS: We inserted modified Gianturco self-expandable stents under the fluoroscopic and bronchoscopic guidance. There were stenosis in the trachea(n--2), the right main bronchus(n=2), and the left main bronchus(n=9). The causes of the stenosis were endobronchial tuberculosis(n=10), intubation granuloma (n=l), restenosis after surgical reconstruction(n=2). RESULTS: Dyspnea or wheezing was improved within 1 or 2 days following the procedure. There were 32% and 22% respective increase in average FEV1 and FVC. Lung perfusion scan showed 9.6% increase of perfusion in the involved lung. No complications related to the procedure were encountered. During follow-up period of up to 31 months, 2 patients showed tracheal or bronchial restenosis, at 3 and 6 months, retrospectively. There was a distal migration of the stents in one case. CONCLUSION: During the follow up period after stent insertion, improvement of the obstructive changes and dyspnea persisted in 10 out of 13 patients. The modified Gianturco self-expandable metallic stents may be a good choice for the treatment of tracheobronchial stenosis, either as a primary treatment, or when the reconstruction failed.
Constriction, Pathologic*
;
Dyspnea
;
Follow-Up Studies
;
Granuloma
;
Humans
;
Intubation
;
Lung
;
Perfusion
;
Respiratory Sounds
;
Retrospective Studies
;
Stents*
6.Combination Chemotherapy with 5-Fluorouracil, Vinblastino and Cisplatin (FVF) in thc Advanced Non-Small Cell Lung Cancer.
Hong Jib CHOI ; Sung Rok KIM ; Sung Hyun YANG ; Soo Jeon CHOI ; Chul Soo KIM ; Re Hwe KIM
Korean Journal of Medicine 1997;53(1):69-75
The 5 year survival rate after surgical resection for stage III non-small cell lung cancer(NSCLC) remains short, only 10-19%. Radiotherapy seems to show some benefit for local control, but it does not reflect to prolongation of survival, as distant metastasis prevails. Vinblastine is one of the most active agent against NSCLC. 5-Fluorouracil(5-FU) and cisplatin are synergistic in anti-cancer activity in adenocarcinoma of gastrointestinal tract and squamous cell cancer of head and neck. We initiated a phase II trial for advanced NSCLC to determine the effect of FVP regimen in response rate, survival and toxicities. The therapy consisted of 5-FU 500mg/m2/12 hours continious IV infusion for 36 hours from day 1, vinblastine 3mg/m2 IV bolus day 1 and 2, cisplatin 75mg/m2 IV infusion over 2 hours day 1 and it was repeated every 3 weeks. Among the 45 patients entered into this study, 40 patients were evaluable for response. The objective response rate was 50%(CR;1/40, 2.5% PRi19/40, 47.5%). The median survival of all the patients was 42.9 weeks(8.4+ - 140.6 weeks); the responding patients survived longer than the non-responders(mediansurvival; 54.4 weeks vs 29.7 weeks, p<0.05). The toxicities of this regimen were acceptable but 1 patient died of pneumonia associated with granulocytopenia. We concluded that the FVP regimen is effective in the treatment of advanced non-small cell lung cancer and a prospective randomized trial and long- term follow up is warranted.
Adenocarcinoma
;
Agranulocytosis
;
Carcinoma, Non-Small-Cell Lung*
;
Cisplatin*
;
Dronabinol*
;
Drug Therapy
;
Drug Therapy, Combination*
;
Fluorouracil*
;
Follow-Up Studies
;
Gastrointestinal Tract
;
Head
;
Humans
;
Lung
;
Neck
;
Neoplasm Metastasis
;
Neoplasms, Squamous Cell
;
Pneumonia
;
Radiotherapy
;
Survival Rate
;
Vinblastine
7.Nursing Bottle Caries.
Dae Yeol LEE ; Soo Chul CHO ; Jung Soo KIM ; Kyu Cha KIM
Journal of the Korean Pediatric Society 1980;23(7):582-585
Feeding habits and sugar contents contents affect dental health and ultimately the total health of young chidren. Nursing bottle caries, nursing botte syndreme, bottle-propping caries are synonymous term for a devastaing condition that may render young children dental cripples. Typically, the primary maxillary incisors are affected most severely and mandibular incisors are seldom involved. We report 4 cases of nursing bottle caries with a brief review of related literatures and references.
Child
;
Humans
;
Incisor
;
Nursing*
8.A case of uterine arteriovenous malformation.
Jae Ho LE ; Sang Wook YI ; Chul Soo JEON ; Se Yong KIM ; Mi Kyung CHANG ; Eung Whan CHOE
Korean Journal of Obstetrics and Gynecology 2000;43(10):1828-1831
No abstract available.
Arteriovenous Malformations*
9.Evolution of serum ferritin levels after renal transplantation.
Sung Hae PARK ; Soo Hyeong LEE ; Hyun Chul KIM ; Won Hyun CHO ; Choal Hee PARK ; Dong Seok JEON
Korean Journal of Nephrology 1992;11(2):159-166
No abstract available.
Ferritins*
;
Kidney Transplantation*
10.Integrating-Types Biomedical Signal Communication System Combined Power Line and Radio Frequency Communication.
Sung Chul KANG ; Soo Young YE ; Gye Rok JEON ; Jae Hyung KIM ; Dong Keun JUNG
Journal of Korean Society of Medical Informatics 2008;14(3):303-309
OBJECTIVES: In order to devise the combination module transmitting bio signal and signal data remotely, as defect of wirewireless combination module was complemented by designing a single combination of wireless module and power supply module, a single system was implemented. METHODS: Currently in case of wireless transmission, it had various problems causing by some factors such as buildings, obstruction, and entanglement of wires and so on. In order to overcome problems of wireless transmission, a single combination module design was researched, which transmits vital signal and sign data using basic electric line installed in the inner building or between others. Even though it was also possible of wireless communication and the internet, in case of a power supply without them, it could be possible to transfer data to underground or top ground in the inner building without any special communication line. RESULTS: Bio signal data was transmitted through a power supply line, a noise problem occurred would be solved by the designed noise filter. The filter showed that noise was cut off about more than 90%. It was also confirmed that the used ECG signals was stably received on transmission experiment. An internal PCB antenna could make the system be wireless communication without the disclosure of an antenna. CONCLUSIONS: In this study, in order to implement a useful system transmitting bio signal and data through wire and wireless management for combination design of wireless module and electrical line module, bio signal transmission system was implemented by design of noise break filter circuit to reduce power noise and PCB internal antenna design.
Complement System Proteins
;
Disclosure
;
Electric Power Supplies
;
Electrocardiography
;
Internet
;
Noise
;
Vital Signs