1.Distribution of the muscarinic receptors and characterization in the brain of wistar rats and spontaneously hypertensive rats(SHR strain) by digital autoradiography.
In SOHN ; Myung Chul LEE ; Chang Soon KOH
Korean Journal of Nuclear Medicine 1993;27(1):28-34
No abstract available.
Autoradiography*
;
Brain*
;
Rats, Wistar*
;
Receptors, Muscarinic*
3.Combined Dexamethasone/Insulin-induced Hypoglyeemic Test in Manic and Schizophrenic Patients.
Si Yong SONG ; Chul Soo PARK ; Jin Wook SOHN
Journal of the Korean Society of Biological Psychiatry 1997;4(2):272-278
Many investigators are trying to elucidate the pathogenesis of psychiatric disorders on the basis of neuroendocrine responses to stimulation or perturbation. Dexamethasone(DEX) suppression has been the most widely utilized as the prototypical challenge test. Dexamethasone suppression test(DST) has proven to be valuable in diagnosing the depressive spectrum disorder. Reported specificity of diagnosis of depression is relatively high, but sensitivity is limited. Some researchers used the combination of dexamethasone and corticotropin releasing hormone(CRH) in order to improve the sensitivity. They reported that combined DEX/CRH test, i.e., we administered the insulin instead of CRH. Total subjects were 28(7 normal controls, 10 manic patients, 11 schizophrenic, patients). Subject were token DEX(1.5mg p.o.) at 11 p.m., insulin 16 hours later(0.1 unit/kg i.v.). Five blood samples for the determination of cortisol and ACTH were serially drawn at 15 minute interval. The results are as following : 1) The cortisol an ACTH levels of manic subjects increased following insulin administration. Manic subjects showed higher levels of cortisol and ACTH than schizophrenic and normal control subjects. The cortisol and ACTH levels of schizophrenic and normal control subjects did not show gross changes. 2) The sensitivity of the test was lower than that of reported DEX/CRH test.
Adrenocorticotropic Hormone
;
Depression
;
Dexamethasone
;
Diagnosis
;
Humans
;
Hydrocortisone
;
Insulin
;
Research Personnel
;
Sensitivity and Specificity
4.A Case of Surgically Extracted Cysticercus Cellulosae from the Anterior Chamber and Three Cases of Subconjunctival Cysticercosis Cellulosae.
Chung Kyoon SOHN ; Seung Ho HONG ; Kyung Chul LEE ; Joon Kiu CHOE
Journal of the Korean Ophthalmological Society 1967;8(1):25-29
The authors experienced a case of anterior uneitis associated with secondary glaucoma caused by a cycitsercosis cellulosae in the anterior chamber of the left eye of a 39-year-old Korean male. The cyst appeared from the posterior surface of the iris through the pupillary margin of 10-o'clock position and grew larger and larger with automatic active movements, filling finally the nasal upper one third of the anterior chamber, but the cyst did not change the position to the 6-o'clock chamber angle. The cysticercus grown for almost four months was extracted successfully with a teethless, serrated, curved forceps with some resistance after opening the anterior chamber from 7~11-o'clock position without iris prolapse and any damage to the anterior lens capsule. The extracted cyst with the size of 8 mm X 6 mm X 3 mm was confirmed as a cysticercus cellulosae by parasitological examinations (Fig. 2,3). After the extraction of the cysticercus the uveitis and the increased intraocular tension subsided completely, remaining some brownish fine keratic precipitates, pigment masses on the anterior surface of the lens and irregularly somewhat dilated pupil due to partial posterior synechia. The naked vision O.S., however, was 20/25 using pin hole, and the eye has been still quiet during last 3 and half years following surgical extraction. In addition the authors have recently seen three cases of subconjunctival cystiticercosis cellulosae. In the first case the cysticercus with the size of 8 mm X 7 mm X 4 mm appeared at the nasal superior part of the bulbar conjunctiva O.D. of a three-year-old Korean male. In the second case the cyst with the size of 7 mm X 5 mm X 3 mm was seen at the nasal inferior part of the bulbar conjunctiva O.S. of a 12-year old Korean female. In the last case the cyst with the size of 10 mm X 8 mm X 5 mm was located beneath the plica semilunaris of 3-o'clock position O.D. of a 58-year-old Korean female. All the cysts were extracted successfully without any rupture, and they were confirmed as the cysticercus cellulosae histologically.
Adult
;
Anterior Chamber*
;
Child
;
Conjunctiva
;
Cysticercosis*
;
Cysticercus*
;
Female
;
Glaucoma
;
Humans
;
Iris
;
Male
;
Middle Aged
;
Prolapse
;
Pupil
;
Rupture
;
Surgical Instruments
;
Uveitis
5.Results of Hook Plate Fixation of Unstable Distal Clavicle Fractures.
Hoon Sang SOHN ; Byung Chul JO
Journal of the Korean Fracture Society 2011;24(4):335-340
PURPOSE: This study evaluated the clinical and radiological outcomes of unstable distal clavicular fractures treated with an AO Hook plate. MATERIALS AND METHODS: From March 2009 to October 2010, sixteen patients with distal clavicular fractures underwent open plating using an AO Hook plate. The clinical outcomes were assessed by measuring the UCLA scores and KSS sores, and the radiological outcomes were evaluated using simple radiographs at the final follow-up. RESULTS: Fracture union was obtained in all patients at an average of 13.9 weeks (range, 9~20 weeks). The UCLA scoring system showed excellent results in 9 cases and good results in 7. The average KSS scores of distal clavicular fractures were 95.5. At the final follow-up, subacromial osteolysis developed in 11 cases (68.7%) of whom 3 suffered from pain around the acromion. Other complications occurred in 4 patients: one had a fracture adjacent to the plate proximally, two had a stiff shoulder with subacromial impingement, and one had hypoesthesia around the surgical wound. CONCLUSION: Unstable distal clavicular fractures treated with a Hook plate provided rigid fixation and satisfactory outcomes considering the high union rate. Nevertheless, potential postoperative complications related to morphometric properties of the plate should be considered.
Acromion
;
Clavicle
;
Follow-Up Studies
;
Humans
;
Hypesthesia
;
Osteolysis
;
Postoperative Complications
;
Shoulder
6.A Case of Mllerian adenosarcoma of vaginal stump after total abdominal hysterectomy.
Kyung Hee LEE ; Eun Mi KOH ; Man Chul PARK ; Yong Woo LEE ; Jin Hee SOHN
Korean Journal of Obstetrics and Gynecology 2000;43(6):1109-1113
Mllerian adenosarcoma of uterus usually present as pedunculated endometrial masses in postmenopausal women with vaginal bleeding. Extraendometrial variants are much less common. A 50-year-old woman, after total abdominal hysterectomy with bilateral salpingo-oophorectomy due to adenomyosis and benign ovarian mass, presented with protruding mass through vagina. The mass, originated from vaginal stump, was diagnosed as Mllerian adenosarcoma. We report a case of extrauterine Mllerian adenosarcoma with a review of literatures.
Adenomyosis
;
Adenosarcoma*
;
Female
;
Humans
;
Hysterectomy*
;
Middle Aged
;
Uterine Hemorrhage
;
Uterus
;
Vagina
7.A case report of sternocostoclavicular hyperostosis: scintigraphic and the confirmative radiographic and CT findings.
Young Min HAN ; Myung Hee SOHN ; Ho Young SONG ; Chong Soo KIM ; Ki Chul CHOI
Journal of the Korean Radiological Society 1992;28(6):973-976
Sternocostoclavicular hyperostosis is a benign ossifying diathetic disorder characterized by hyperostosis and soft tissue ossification of the clavicles, anterior portion of the first ribs, and manubrium, with variable hyperostosis or ankylosis in the spine and sacroiliac joints. A review of the literature and our own case describes the clinical findings and its characteristic features in RI, CT, and plain film.
Ankylosis
;
Clavicle
;
Hyperostosis
;
Hyperostosis, Sternocostoclavicular*
;
Manubrium
;
Ribs
;
Sacroiliac Joint
;
Spine
8.Effects of recombinant human erythropoietin therapy in hemodialysis patient.
Seong Soo CHO ; Jun Ho LEE ; Soo Ho SOHN ; Sung Bae PARK ; Hyun Chul KIM
Korean Journal of Nephrology 1993;12(1):68-75
No abstract available.
Erythropoietin*
;
Humans*
;
Renal Dialysis*
9.Hand-Washing Practices Followed by Health Care Workers in a Tertiary Care Hospital Depending on Their Carriage Status for Nasally Transmitted Methicillin-Resistant Staphylococcus aureus.
Seung Eun LEE ; Min Ja KIM ; Jang Wook SOHN ; Byung Chul CHUN
Korean Journal of Nosocomial Infection Control 2011;16(1):18-28
BACKGROUND: Hospital-wide surveillance showed an up to 9% increase in the incidence rate of the nasal transmission of methicillin-resistant Staphylococcus aureus (MRSA) among health care workers (HCWs) in a tertiary care hospital where MRSA is endemic. The purpose of this study was to investigate the knowledge of and attitude towards nasal transmission of MRSA and hand-washing practice among HCWs and determine the behavioral factors associated with the nasal transmission of MRSA. METHODS: In a 750-bed tertiary care hospital, nasal swabs from HCWs were obtained, and questionnaires with 25 questions were distributed to HCWs who were divided into 2 different groups: MRSA carriers and non-carriers. The questionnaires focused on the HCWs' knowledge about the mode of MRSA transmission and precautions against MRSA infection and their self-reported compliance for hand hygiene. RESULTS: The total number of respondents for the surveillance culture and survey were 253 (51 MRSA carriers and 202 non-carriers). There was significant difference between the 2 groups on the knowledge of precautionary measures used for the MRSA patients in the hospital (P=0.026). Compared to the MRSA carriers, the non-carriers washed their hands significantly more frequently after ventilator care (P=0.004) and used more alcohol sanitizers (P=0.023). However, no significant difference was observed in hand-washing practices of both the groups before the medical procedures, their knowledge about the mode of transmission of MRSA, and the duration of hand washing. CONCLUSION: Non-carriers replied more accurately to the questions on knowledge about the management and treatment of MRSA, and they considered interventions such as surveillance cultures and questionnaires to be an effective method in lowering the incidence of nosocomial infections. Compared to the MRSA carriers, the non-carriers showed higher hand-washing compliance.
Compliance
;
Cross Infection
;
Cross-Sectional Studies
;
Surveys and Questionnaires
;
Delivery of Health Care
;
Drug Resistance
;
Hand
;
Hand Disinfection
;
Humans
;
Incidence
;
Methicillin Resistance
;
Methicillin-Resistant Staphylococcus aureus
;
Tertiary Healthcare
;
Ventilators, Mechanical
10.Clinical observation on prematurity subjected for EEG.
Chul Soon PARK ; Soon Wha KIM ; Don Hee AHN ; Keun Chan SOHN
Journal of the Korean Pediatric Society 1993;36(6):778-784
This study included fifty two premature babies in whom EEG was performed at National Medical Center, from Jan. 1990 to Jun. 1991. clinical and EEG records of all subjects were analyzed and the following results were obtained. 1) The day of first EEG performed were;11 cases within 10 days, 20 cases from 11 days to days, 13 cases from 21 days to 30 days and 8 cases beyond 31 days. 2) The results of first EEG were; within normal limit in 34 cases, mild abnormality in 3 cases, moderate abnormality in 11 cases and marked abnormality in 4 cases. 3) The abnormal EEG ratio according to the sex was higher in female than in male (43.5% vs 27.6%). 4) The abnormal EEG ratio according to the gestational age was higher in shorter gestational age group than in longer gestational age group (40.9% under 32 weeks of G.A. vs 30.0% beyond 33 weeks of G.A.). 5) The abnormal EEG ratio according to the birth weight was not significant. 6) The abnormal EEG ratio according to the ventilator use was higher in used group than in not used group (38.5% vs 30.8%). 7) Combined diseases in 18 cases of abnormal EEG group were jaundice (14 cases), hyaline membrane disease (7 cases), asphyxia (4 cases), anemia (4 cases), hydrocephalus, sepsis, PDA, hypocalcemia, UTI and IVH. 8) The mean apgar score in abnormal EEG group was lower than normal EEG group both in one minute and five minute. 9) Two cases among 18 cases of abnormal EEG group showed abnormal brain sonographic findings, but one case among 34 cases of normal EEG group showed abnormal brain sonographic finding. 10) Ten cases were followed up with serial EEG, six cases of which were treated with anticonvulsant. We observed normalization of the EEG in 5 cases of anticonvulsant treated group.
Anemia
;
Apgar Score
;
Asphyxia
;
Birth Weight
;
Brain
;
Electroencephalography*
;
Female
;
Gestational Age
;
Humans
;
Hyaline Membrane Disease
;
Hydrocephalus
;
Hypocalcemia
;
Infant, Newborn
;
Jaundice
;
Male
;
Sepsis
;
Ultrasonography
;
Ventilators, Mechanical