This clinical and histopatholgical study was performed with 149 cases of acquired melanocyticnevi, which were obtained as surgical specimens from 1975 to 1985 at Depa.rtment of Clinical Pathology, Seoul Red Cross Hopital. The results were as follows: 1) Histologic subdivision of melanocytic nevus into junctional(,J), IJC, compound (C,"), ICI, and intradermal(I) is used. IJC is a lesion in an intermediate state between ,junctional and compound nevus, and ICI, between compound and intradermal nevus. 2) The age distribution of the excisional melanocytic nevus peaks during the third decade of life, with 47% of patients between 21 40 year old of age. 3) Of l49 specimens with excisional melanocytic nevus, the number of junctional, IJC, compound, ICI and intradermal nevus were 17, 4, 21, 32 and 75 in each group And so, it is likely that evolution of the melanocytic nevus have an increased opportunity for surgical excision. 4) Among the 17 cases of junctional nevus, one case is found in 5th and the other one in 7th decade. 5) In distvibution of melanocytic nevus, head including face is the most common site among the body area and then trunk, neck, lower and upper extremity in decreasing orders.
Adult ; Age Distribution ; Head ; Humans ; Neck ; Nevus ; Nevus, Intradermal ; Nevus, Pigmented* ; Pathology, Clinical ; Red Cross ; Seoul ; Upper Extremity

Eccrine angiomatous hamartoma or sudoriparous angioma is a hamartoma in which histologically, hyperplasia of eccrine sweat apparatus and vascular elements is present in the same lesion and clinically has tenderness and hyperhidrosis over the lesion. We present a case of eccrine angiomatous hamartoma developed on the medial side of the right knee in a 5-year-old female patient.
Child, Preschool ; Female ; Hamartoma* ; Hemangioma ; Humans ; Hyperhidrosis ; Hyperplasia ; Knee ; Sweat

No abstract available.
Female ; Menstrual Cycle* ; Pregnancy Rate* ; Pregnancy*

No abstract available.
R Factors* ; Shigella*

Isolated ACTH deficiency is a rare disorder, and usually characterized by its chronic course. The 59 year-old woman patient who had been healthy until 2 months ago, admitted because of abdomial pain, general weakness and loss of weight about 12kg for 2 months. She looked a little pallor but color of skin was not remarkable. Blood pressure, serum electrolyte, and glucose on admission were within normal range. Serum calcium was elevated with the value of 12.6mg/dL, which was normalized after hydration. Cortisol response to RI induced hypoglycemia did not show any response. Anterior pituitary hormone except ACTH showed normal response during combined pituitary hormone stimulation test. These clinical and laboratory finding reveals that isolated ACTH deficiency was developed in a short term period. There were no abnormalities in sellar MRI except pineal cyst. Her complaints were disappeared dramatically after hydroccetisone replacement at 4th. hospital day. Here we report a case of isolated ACTH deficiency, which was rapidly developed, with hypercalcemia, abdominal pain, and loss of weight about 12kg for 2 months.
Abdominal Pain ; Adrenocorticotropic Hormone* ; Blood Pressure ; Calcium ; Female ; Glucose ; Humans ; Hydrocortisone ; Hypercalcemia ; Hypoglycemia ; Magnetic Resonance Imaging ; Middle Aged ; Pallor ; Reference Values ; Skin ; Weight Loss

Benign prostatic hyperplasia and urethral stricture are common causes of urethral obstruction over 50 years of age. To evaluate the usefulness of the Gianturco expandable stent for dilatation of the urethra, 14 single stents were placed in the posterior urethra (2 in prostatic urethra, 12 in membranous urethra), 20 in the anterior urethra. And 4 six-eight connected stents ere positioned in the posterior urethra to straddle at the internal sphincter or external sphincter and followed up for 2 weeks (one dog), 1 month (two dog), 2 months (one dog), 3 months (one dog), 5 months (one dog), 9 months (three dogs), and 14 months (two dogs). Seven of 18 stents in the posterior urethra and 5 to 20 in the anterior urethra were migrated during the follow-up. By 2 weeks after placement. 100% expansion was achieved in the posterior urethra, but by 1 month in the anterior urethra. Partial or complete epithelial covering of the stents was observed 1 month after stent placement in the anterior urethra, but mucosal folds were observed in the anterior and posterior urethra. Urinary incontinence was not observed in all cases. Our experience suggests that Gianturco expandable stent can be used in dilating and maintaining the lumen of the prostatic urethra and urethral stricture.
Animals ; Dilatation ; Dogs* ; Follow-Up Studies ; Prostatic Hyperplasia ; Stents* ; Urethra* ; Urethral Obstruction ; Urethral Stricture ; Urinary Incontinence

We examined the hypothesis that mild hypothermia (rectal temperature 34 degrees C) results in the same survival time, whether induced spontaneously or intentionally, during untreated, lethal, uncontrolled hemorrhagic shock in rats. Sixty-four Sprague-Dawley male rats were randomly assigned to normothermia (Nth) (n=19), spontaneous mild hypothermia (Sp.Hth) (n=25) or controlled mild hypothermia (Con.Hth) (n=20) groups. After blood withdrawal of 3 mL/100 g over 15 minutes, followed by 75% tail amputation under spontaneous breathing and light anesthesia by i.p. injection of pentobarbital sodium, rats were observed without fluid resuscitation or hemostasis for 180 minutes or until death. The initial temperature of the Nth group was artificially maintained throughout the experiment. For the mild hypothermia groups, the Sp.Hth group was exposed to ambient temperature while the Con. Hth group was actively cooled to a target rectal temperature of 34 degrees C. In the Con.Hth group, all rats except one died before 180 minutes. All rats in the Nth group died within 38 minutes, and within 67 minutes in the Sp.Hth group. The average survival time was shortest in the Nth group at 20.3 +/- 5.3 minutes, followed by the Sp.Hth group at 30.1 +/- 13.5 minutes, and the Con.Hth group at 81.9 +/- 39.8 minutes (p 0.01). Tail bleed out volume was 0.51 +/- 0.19, 0.26 +/- 0.15 and 0.19 +/- 0.12 mL/100 g in the Nth, Sp.Hth and Con.Hth groups, respectively (p 0.05). In conclusion, spontaneous mild hypothermia did not prolong the survival time as much as controlled mild hypothermia in the rat model for untreated, lethal, uncontrolled hemorrhagic shock.
Animal ; Blood Pressure ; Body Temperature ; Hypothermia/*physiopathology ; *Hypothermia, Induced ; Male ; Rats ; Rats, Sprague-Dawley ; Shock, Hemorrhagic/*mortality/physiopathology/therapy

The authors have experienced a case of extrascleral extension of choroidal malignant melanoma. The patient has suffered from the ocular pain and proptosis of right eye. We performed Kronlein operation under the clinical impression of the retrobulbar mass and obtained the histopathological diagnosis of malignant melanoma. Fifteen days after the operation, we performed exenteration and the rotation flap of temporalis muscle was inserted into the right eye ball socket through the lateral wall of the orbit.
Choroid* ; Diagnosis ; Exophthalmos ; Humans ; Melanoma* ; Orbit

PURPOSE: This study was performed to evaluate the usefulness of propofol in radiology studies by comparing propofol sedation with midazolam for patients who do not comply with their doctor's requests and need an injection of a sedative to be treated for a safe and quick recovery without complications. METHODS: Among adult patients who were admitted and checked using CT and MRI in our emergency medical center from February 2001 to August 2001, the patients who required sedation because of the lack of cooperation with ER doctors were studied. Of 49 patients, 23 patients (Group M) were injected with midazolam, and 26 patients (Group P) were injected with propofol. RESULTS: In both groups, the systolic BP and the diastolic BP decreased, but group P's BP decreased more than group M's (p<0.05). In group M, the decrease of SPO2 w a s statistically significant, but neither of the groups required emergency care. Although, Group M didn't require emergency care for SpO2, they did require more emergency care for apnea than Group P did. Group P's time required for an examination to be performed was shorter than group M's. Group P's duration for occurrence of movement was shorter than Group M's, but this difference was not statistically significant. Regardless of which sedative was used, there was no difference in the satisfaction of the radiology technician with regards to group M and group P. CONCLUSION: When the patients were injected with a lowdosage of propofol, they showed effects similar to those observed in patients in injected with midazolam, and there were no complications that required emergency care. The usage of propofol is thought to be a good choice, except for contraindications, for short-time radiology examinations.
Adult ; Apnea ; Emergencies* ; Emergency Medical Services ; Humans ; Magnetic Resonance Imaging ; Midazolam* ; Propofol*

Aldosterone-producing adrenal adenoma can induce various clinical manifestations as a result of chronic exposure to aldosterone. We report a rare case of a 37-year-old man who complained of general weakness and polyuria. He was diagnosed with aldosterone-producing adrenal adenoma and nephrogenic diabetes insipidus. Aldosterone enhances the secretion of potassium in the collecting duct, which can lead to hypokalemia. By contrast, nephrogenic diabetes insipidus, which manifests as polyuria and polydipsia, can occur in several clinical conditions such as acquired tubular disease and those attributed to toxins and congenital causes. Among them, hypokalemia can also damage tubular structures in response to vasopressin. The patient's urine output was > 3 L/d and was diluted. Owing to the ineffectiveness of vasopressin, we eventually made a diagnosis of nephrogenic diabetes insipidus. Laparoscopic adrenalectomy and intraoperative kidney biopsy were subsequently performed. The pathologic finding of kidney biopsy revealed a decrease in aquaporin-2 on immunohistochemical stain.
Adenoma ; Adrenalectomy ; Adult ; Aldosterone ; Aquaporin 2 ; Biopsy ; Diabetes Insipidus ; Diabetes Insipidus, Nephrogenic* ; Diagnosis ; Humans ; Hyperaldosteronism* ; Hypokalemia ; Kidney ; Polydipsia ; Polyuria ; Potassium ; Vasopressins