1.A Case of Delayed Intracerebellar Hematoma after Head Injury.
Sahng Hyun KIM ; Kum WHANG ; Jin Soo PYEN ; Chul HU ; Soon Ki HONG ; Young Pyo HAN
Journal of Korean Neurosurgical Society 2000;29(3):407-410
No abstract available.
Craniocerebral Trauma*
;
Head*
;
Hematoma*
2.Mediastinal tuberculous abscess: report of two cases.
Hyeon In PYO ; Ho Seong SHIN ; Byeong Joo KIM ; Hee Chul PARK ; Ki Woo HONG
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(8):830-835
No abstract available.
Abscess*
3.Clinical evaluation of 111 cases of open heart surgery.
Hyeon In PYO ; Ho Seong SHIN ; Byeong Joo KIM ; Hee Chul PARK ; Ki Woo HONG
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(9):870-880
No abstract available.
Heart*
;
Thoracic Surgery*
4.Two Cases of Extramammar Paget's Disease.
Duck Pyo HONG ; Eil Soo LEE ; Dong Chul KIM ; Kye Yong SONG
Korean Journal of Dermatology 1986;24(5):712-716
We have experienced two cases of extramammary Paget's disease. The first case was a 68-year-old male who showed erythematous, crusted, oozing, eczematoid patches on the scroturn, penile root and pubic area, and verrucous plaque on the left pubic area of 5 years' duration. The second case was a 60-year-old male who showed erythematous, oozing, hyperkeratotic plaque and nodular mass on the scrotum of 4 years' duration. In electron microscopic findings of the first case, the Paget's cells was suggested to be formed by pleuripotential germinative cells; well developed microvilli, numerous electron lucent secretory granules, a few electron dense granules, apocrine type secretion and well developed desmosome.
Aged
;
Desmosomes
;
Humans
;
Male
;
Microvilli
;
Middle Aged
;
Paget Disease, Extramammary
;
Scrotum
;
Secretory Vesicles
5.Drug resistance of mycobacterium tuberculosis in Korea.
Sang Jae KIM ; Young Pyo HONG ; Yong Chul HAN ; Sung Jin KIM
Tuberculosis and Respiratory Diseases 1991;38(2):99-107
No abstract available.
Drug Resistance*
;
Korea*
;
Mycobacterium tuberculosis*
;
Mycobacterium*
6.Clinical Analysis of Cranial Nerve Injuries in Craniocerebral Trauma.
Jang Soo YOO ; Young Pyo HAN ; Hun Joo KIM ; Soon Ki HONG ; Chul HU
Journal of Korean Neurosurgical Society 1991;20(1-3):20-27
The clinical analysis of cranial nerve injuries was performed on 435 cases with cranoicrerbral trauma. This prospective study included the correlation between cranial nerve injuries and risk factors such as intracranial hematoma, initial Glasgow Coma Scale(GCS) score, pneumocephalus, and other combined injuries. The results were revealed as follows : 1) 133 cranial nerve injuries(on 97 patients) were noted among 435 craniocerebral trauma victims(97/435=22.2%). 2) The order of frequent cranial nerve injuries was facial nerve(7.3%), olfactory nerve(6.9%), oculomotor nerve(4.4%), abducens nerve(3.9%), optic nerve(3.2%), etc. 3) Bilateral involvment of cranial nerve injuries was noted in 16.5%(22/133). 4) The incidence of immediate onset of cranial nerve injuries was 66.9%(89/133). 5) The incidence of cranial nerve injuries was significantly high in patients with pneumocephalus and low initial GCS score. 6) The functional recovery of injured cranial nerve within 3 months was noted in 30.1%(40/133).
Coma
;
Cranial Nerve Injuries*
;
Cranial Nerves*
;
Craniocerebral Trauma*
;
Hematoma
;
Humans
;
Incidence
;
Pneumocephalus
;
Prospective Studies
;
Risk Factors
7.Clinical Analysis of Interhemispheric Subdural Hemorrhage and Tentorial Hemorrhage.
Jang Soo YOO ; Chul HU ; Soon Ki HONG ; Hun Joo KIM ; Yong Pyo HAN
Journal of Korean Neurosurgical Society 1991;20(1-3):13-19
A propecive analysis of 50 patients with acute interhemisphric subdural hemorrhage and tentorial hemorrhage, an unusual pattern of acute subdural hematoma, who were managed in a uniform way was analyzed to related outcome to hemorrhagic site, initial Glasgow Coma Scale(GCS) and combined injuries. The incidence of acute interhemisphric subdural hemorrhage(ISH) and tentoria hemorrhage(TH) after head trauma was 3.83%, 50 cases among 1303 head injured cases. And 80% of the above hemorrhage disapperaed within two weeks after trauma. There was no significant relationship between feature of hemorrhage and intial GCS(P>0.05), but there was highly significant relationship between initial GCS and Glasgow Outcome Scale(GOS) (p<0.001). There noted significant relationship between initial combined injury and GOS(p<0.01), and also brainstem injury and GOS(p<0.001).
Brain Stem
;
Coma
;
Craniocerebral Trauma
;
Head
;
Hematoma, Subdural*
;
Hematoma, Subdural, Acute
;
Hemorrhage*
;
Humans
;
Incidence
8.Deep Vein Thrombosis and Pulmonary Embolism after Cementless Total Hip Arthroplasty.
Myung Chul YOO ; Yoon Je CHO ; Chang Moo YIM ; Gyu Pyo HONG ; Jin Moon KIM
The Journal of the Korean Orthopaedic Association 1998;33(7):1672-1680
Thromboembolism is the most common serious complication following total hip arthroplasty and most common cause of death after total hip arthroplasty. A prospective randomized study in 170 cases of elective cementless total hip arthroplasty was carried out to examine the incidence of deep vein thrombosis and pulmonary embolism after cementless total hip arthroplasty from Aug. 1993 to May 1995. Laboratory study, clinical symptoms and signs, chest roentgenograph and precipitating factors were analysed. Venography and lung perfusion scan using radionuclide scan were used for this study. The weight, height, sex, habitus of alcohol and smoking, hypertension, diabetes mellitus, previous operation history of ipsilateral lower extremity, etiology of hip joint disease, and transfusion of blood were not precipitating factors, but the age over 40 and previous history of pulmonary embolism had a significant effect on the incidence of deep vein thrombosis. There was no significant relationship between the incidence of deep vein thrombosis and the laboratory assay, clinical symptoms and signs. Deep vein thrombosis was detected in 29 cases(17.0%), pulmonary embolism in 22 cases(12.9%), and fatal pulmonary embolism in 1 case(0.6%). The most common location of deep vein thrombosis was the popliteal area.
Arthroplasty, Replacement, Hip*
;
Cause of Death
;
Diabetes Mellitus
;
Hip Joint
;
Hypertension
;
Incidence
;
Lower Extremity
;
Lung
;
Perfusion
;
Phlebography
;
Precipitating Factors
;
Prospective Studies
;
Pulmonary Embolism*
;
Smoke
;
Smoking
;
Thorax
;
Thromboembolism
;
Venous Thrombosis*
9.Clinical Significance of Plasma TGF-β1 in Coal Workers' Pneumoconiosis.
Chong Ju KIM ; Won Yeon LEE ; Ae Ra HONG ; Pyo Jin SHIN ; Suk Joong YONG ; Kye Chul SHIN
Tuberculosis and Respiratory Diseases 2001;50(1):76-83
BACKGROUND: Coal workers' pneumoconiosis is a fibrotic lung disease resulting from chronic inhalation of coal dust. The precise mechanism of lung fibrosis in coal workers' pneumoconiosis is uncertain. However, a relationship between the stimulation of fibroblast proliferation and collagen production by mediators released from inflammatory and resident lung cells is thought to be a major factor. The transforming growth factor-β(TGF-β), a multifunctional cytokine and growth factor, plays a key role in the scarring and fibrotic processes due to its ability to induce extracellular matrix proteins and modulate the growth and immune function of many cell types. To determine the involvement of TGF-βin the development of lung fibrosis in coal workers' pneumoconiosis, the TGF-β1 level in plasma was measured in patients with coal workers' pneumoconiosis. METHODS: Plasma was collected from 40 patients with coal workers' pneumoconiosis (20 with simple coal workers' pneumoconiosis and 20 with complicated coal workers' pneumoconiosis) and from 10 normal controls. The ELISA method was used to measure the plasma TGF-β1 concentration. RESULTS: Compared to the control group (0.63±0.18 ng/mL), there was no significant difference in the plasma TGF-β1 level in patients with simple coal workers' pneumoconiosis (0.64±0.17 ng/mL) (p>.05). However, in patients with complicated coal workers' pneumoconiosis the plasma TGF-β1 level (0.79±0.18 ng/mL) was significantly higher than in patients with simple coal workers' pneumoconiosis and control group (p<0.05). CONCLUSION: The data suggests that TGF-β1 has some influence in the development of lung fibrosis in coal workers' pneumoconiosis.
Cicatrix
;
Coal*
;
Collagen
;
Dust
;
Enzyme-Linked Immunosorbent Assay
;
Extracellular Matrix Proteins
;
Fibroblasts
;
Fibrosis
;
Humans
;
Inhalation
;
Lung
;
Lung Diseases
;
Plasma*
;
Pneumoconiosis*
;
Pulmonary Fibrosis
10.Gastrointestinal Bleeding in Neurosurgical Patient.
Seng Yun KOH ; Soon Ki HONG ; Yong Pyo HAN ; Chul HU
Journal of Korean Neurosurgical Society 1988;17(6):1303-1308
After the definition of Cushing's ulcer, it is well recognized that neurosurgical patients have the high risk of acute gastrointestinal bleeding, especially in severe head trauma. Acute gastrointestinal bleeding after burn, respiratory failure, hepatic failure, renal failure and sepsis as "stress ulcer" also were studied. The prevention and management of bleeding was discussed in medico-surgical field for several years. Despite of these regimen, the prognosis of the bleeding have not significantly improved and bleeding affected the patient's outcome more than initial neurosurgical intervention. The authors experienced 25 cases of acute gastrointestinal bleeding among our neurosurgical patients between January, 1984 to June, 1988. We analysed these patients respectively and concluded as follows: 1) The incidence of acute gastrointestinal bleeding was 0.61%. 2) The bleeding developed on 12th day, average, and clinical manifestation were anemia, hematemesis and melena in order of frequency within the first 4-week in almost all cases. 3) The initial neurological sign such Glasgow Coma Scale may well predict the hallmark to suspect the acute gastrointestinal bleeding. 4) The systemic insults such as shock, renal failure, hepatic failure, respiratory failure and sepsis significantly affected to re-bleeding chance and rendered the patient's outcome poorer. 5) The overall mortality due to gastrointestinal bleeding was 32% and the operative mortality was 50%.
Anemia
;
Burns
;
Craniocerebral Trauma
;
Glasgow Coma Scale
;
Hematemesis
;
Hemorrhage*
;
Humans
;
Incidence
;
Liver Failure
;
Melena
;
Mortality
;
Prognosis
;
Renal Insufficiency
;
Respiratory Insufficiency
;
Sepsis
;
Shock
;
Ulcer