1.Clinical Application of Polymerase Chain Reaction for Diagnosis of Pulmonary Tuberculosis in Pneumoconiotic Patient.
Jae Hee PARK ; Chul Jae LIM ; Kyung Hye LEE
Korean Journal of Occupational and Environmental Medicine 1998;10(1):20-28
Recent development in thepolymerase chain reaction (PCR) has brought an extraordinary opportunity for the rapid detection of M. tuberculosis in clinical specimens for the diagnosis of tuberculosis. Pneumoconiosis is a sort of pulmonary fibrosis consequent to inhalation of the respirable dust. The association between pulmonary tuberculosis and pneumoconiosis is well recognized. There is a 10-fold increase in the tuberculosis risk among the workers who have pneumoconiosis demonstrated by chest roentgenogram. The physicians managing the patients with pneumoconiosis have to maintain a high index of suspicion for the development of mycobacterial infection, since the diagnosis of tuberculosis is often difficult. Mycobacterium tuberculosis is a very slow growing organism and acid-fast bacillus (AFB) staining frequently shows false negative results, and therefore PCR would be a very rapid, easy and sensitive diagnostic method for the diagnosis of Mycobacterium tuberculosis in pneumoconiotic patients. To compare the PCR method with the conventional methods in diagnosing Mycobacterium tuberculosis in sputum, we used the sputa of 115 pneumoconiosis patients in Munkyeong Cheil Hospital. Of 32 pulmonary tuberculosis in the pneumoconiosis patients, 29 were PCR positive and were higher than 28, 20 positive by culture and AFB stain. Overall sensitivity, specificity, and which were 90.6, 91.5 % respectively for the PCR assay, 87.5, 100 % for the culture method ; 62.5, 98.7 % for the AFB stain. The PCR assay is a rapid, efficient, sensitive method which can detect M. tuberculosis directly in pneumoconiosis patients, and further study should be followed for the development of the easier method.
Bacillus
;
Diagnosis*
;
Dust
;
Humans
;
Inhalation
;
Mycobacterium tuberculosis
;
Pneumoconiosis
;
Polymerase Chain Reaction*
;
Pulmonary Fibrosis
;
Sensitivity and Specificity
;
Sputum
;
Thorax
;
Tuberculosis
;
Tuberculosis, Pulmonary*
2.A study on post-operative complications of radical abdominal hysterectomy with pelvic lymph node dissection.
Jeong Won KANG ; Chul Soo LIM ; Jae Hoon CHUNG
Korean Journal of Obstetrics and Gynecology 1991;34(2):245-252
No abstract available.
Hysterectomy*
;
Lymph Node Excision*
;
Lymph Nodes*
3.A study on post-operative complications of radical abdominal hysterectomy with pelvic lymph node dissection.
Jeong Won KANG ; Chul Soo LIM ; Jae Hoon CHUNG
Korean Journal of Obstetrics and Gynecology 1991;34(2):245-252
No abstract available.
Hysterectomy*
;
Lymph Node Excision*
;
Lymph Nodes*
4.Clinicopathologic study and ultrasonographic finding of pelvic mass.
Chul Soo LIM ; Yeon PARK ; Jae Hoon CHUNG
Korean Journal of Obstetrics and Gynecology 1991;34(1):70-80
No abstract available.
5.Application of a New Colostomy Device in Incontinent Dog Model.
Myeung Kook LIM ; Jae Hwang KIM ; Min Chul SHIM
Journal of the Korean Society of Coloproctology 1998;14(3):439-446
BACKGROUND: Recently developed electrically stimulated gracilis neosphicter or artificial sphincter is quite a promising trial in fecal incontinence However, surgical technique is not simple, the devices are expensive and only specialists can perform the procedures successfully. The aim of this study is to evaluate the efficacy of a newly developed simple silicon device in incontinent dog model. METHODS: A New Colostomy Device (NCD; US Patent No. 5,569,216) for fixing in the stoma or rectum of human body, includes an internal balloon, a ring figured extemal balloon surrounding the internal balloon, a connecting tube disposed under the both infernal and external balloons and supply tube containing a pair of air passages and an enema fluid passage. It is designed to be inserted into the rectum and is held in place by an inflatable external balloon and drains irrigated fecal matter through a thin collapsible connecting tube which exist in the anal canal. Six mongrel dog with 22~26 kg of body weight were prepared. Anal incontinence was made by bilateral severing of the internal and external sphincters and puborectalis muscle under the general anesthesia. Marlex mesh ring was applied to the anal canal as Thiersch wire for the prevention of NCD expulsion in straining. After then, NCD with 2.5 cm of luminal diameter was inserted to the rectum proximal to the Malex mesh ring. Daily irrigation and evacuation was done with 800~1000 cc of tepid water in each dogs. Daily food contained 30 gm of Psyllium dextrose. RESULTS: Initially 6 dogs were observed for 7 days. Daily irrigation made evacuation of fecal matter well in each dogs. There was no prolapse of device through the anal orifice. Anoscopic examination after 7 days showed no rectal and anal mucosal injury. Two dogs were kept for 40 days as same manner. Sometimes spontaneous bowel movement without water irrigation was noted when the stool were loose. Weelky anoscopic examination revealed no evidence of mucosal injuries for 40 days also. There was no septic or other complication. CONCLUSION: NCD evacuated fecal matter well enough to empty the rectum in all incontinence dog model. Adequate sized NCD could be used for clinical trials in selected incontinence patients.
Anal Canal
;
Anesthesia, General
;
Animals
;
Body Weight
;
Colostomy*
;
Dogs*
;
Enema
;
Fecal Incontinence
;
Glucose
;
Human Body
;
Humans
;
Phenobarbital
;
Polypropylenes
;
Prolapse
;
Psyllium
;
Rectum
;
Silicones
;
Specialization
;
Water
6.Congenital Pseudarthrosisof the Tibia: Treated with Free Vascularized Fibular Graft
Myung Chul YOO ; Shin Hyeok KANG ; Bong Keon KIM ; Jae Gong PARK ; Hong Chul LIM
The Journal of the Korean Orthopaedic Association 1981;16(3):745-752
It is notoriously difficult to obtain a sound bony union of congenital paeudarthrosis of tbe tibia with conventional methods. This paper is the results of using the free vascularized fibular graft for congenital pseudarthorsis of the tibia in 7 patients since 1978 in this hospital, which is the first attempt in Korea. During the follow-up periods from 9 months to 32 months, 5/7 patients(71%) had good or excellent bony union, 2 patients had bone resorption at tbe distal site of grafted bone and required a second supplementary cancellous bone graft with electrode insertion. So it is thought that the free vascularized fibular graft is one of good methods of treatment for congenital pseudarthrosis of the tibia.
Bone Resorption
;
Electrodes
;
Follow-Up Studies
;
Humans
;
Korea
;
Pseudarthrosis
;
Tibia
;
Transplants
7.Compartment Syndrome of the Upper Extremity Induced by Extravasation of Contrast Media after Computed Tomography: A Case Report.
Jae Won JUNG ; Young Jae LIM ; Beom Soo KIM ; Chul Hyun CHO
Clinics in Shoulder and Elbow 2017;20(4):240-243
The incidence of contrast media extravasation has been increasing gradually. Most contrast media extravasations only can cause pain, swelling and erythema. However, in more severe cases, skin necrosis, ulceration, or compartment syndrome may occur, often necessitating a surgery. Early diagnosis and treatment should be established on the spot in order to avoid such a severe damage. We present a case of 42-year-old woman with a compartment syndrome in the right upper extremity caused by extravasation of computed tomography contrast media.
Adult
;
Compartment Syndromes*
;
Contrast Media
;
Early Diagnosis
;
Erythema
;
Extravasation of Diagnostic and Therapeutic Materials*
;
Female
;
Humans
;
Incidence
;
Necrosis
;
Skin
;
Ulcer
;
Upper Extremity*
8.Serotype of rickettsia Tsutsugamushi isolated in Ulsan area.
Jae Seung KANG ; Byung Uk LIM ; Yong Lim KIM ; Dong Chul PARK ; Jun Tack JO ; Jin Kwan LEE
Korean Journal of Infectious Diseases 1992;24(3):179-182
No abstract available.
Orientia tsutsugamushi*
;
Rickettsia*
;
Ulsan*
9.Infantile Hypertrophic Pyloric Stenosis Treated with Intravenous Atropine Sulfate.
Jae Woo LIM ; Hee Sook SON ; Kye Shik SHIM ; Kyu Chul CHOEH ; Tae Il HAN
Journal of the Korean Pediatric Society 2000;43(6):763-768
PURPOSE: The pharmacologic effect of atropine on HPS can be considered to control pyloric muscle spasm. Therefore, we studied the effects of intravenous atropine sulfate on the clinical course of HPS, and periodically observed the ultrasonographic appearance of the pyloric muscles after atropine treatment. METHODS:From April 1998 to May 1999, 14 infants who were diagnosed with HPS were treated with intravenous atropine sulfate. Intravenous atropine sulfate was administered at an initial dose of 0.04mg/kg/day, which was divided into 8 equal doses. The daily dose was increased by 0.01 mg/kg/day until vomiting was controlled for an entire day while infants received unrestricted oral feeding. Ultrasonographic examinations were performed during hospitalization and repeated at least every 2 months until normalization of pyloric muscles was confirmed. RESULTS: Intravenous atropine was effective in 12 of 14 infants with HPS and the conditions of 9 of them improved. Two infants who were not free from vomiting despite a week of intravenous atropine sulfate treatment underwent pyloromyotomy. A series of ultrasonographic examinations were done after vomiting had improved with intravenous atropine sulfate. The ultrasonographic findings showed good passage of gastric contents through pyloric canals despite thickening of the pyloric muscles. CONCLUSION: Intravenous administration of atropine sulfate is an effective therapy for HPS and can be an alternative to pyloromyotomy. (J Korean Pediatr Soc 2000;43:763-768)
Administration, Intravenous
;
Atropine*
;
Hospitalization
;
Humans
;
Infant
;
Muscles
;
Pyloric Stenosis, Hypertrophic*
;
Spasm
;
Vomiting
10.A Clinical Study of Wet Lung Disease.
Soon Wook LIM ; Jae Seung YANG ; Chul LEE ; Dong Gwan HAN ; Chin Suck SUH
Journal of the Korean Pediatric Society 1985;28(9):852-860
No abstract available.
Pulmonary Edema*